Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P54652

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
14	matrix metallopeptidase-2	11-28	N		MS	Schilling & Overall, 2008
17	matrix metallopeptidase-2	8-26	N		MS	Schilling & Overall, 2008
22	cathepsin G	4-37	N		MS	Schilling & Overall, 2008
26	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
28	glutamyl endopeptidase I	1-639	N		MS	Schilling & Overall, 2008
37	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
50	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
57	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
139	matrix metallopeptidase-2	138-156	N		MS	Schilling & Overall, 2008
143	matrix metallopeptidase-2	142-156	N		MS	Schilling & Overall, 2008
156	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
223	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
230	cathepsin G	224-239	N		MS	Schilling & Overall, 2008
239	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
302	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
314	trypsin 1	1-639	N		MS	Schilling & Overall, 2008
335	meprin alpha subunit	332-345	N		MS	Becker-Pauly et al., 2011