Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P54252

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
145	caspase-3	1-376	P	normal turnover		Ellerby et al., 1999
171	caspase-3	1-376	P	normal turnover		Ellerby et al., 1999
228	caspase-3	1-376	P	normal turnover		Ellerby et al., 1999
241	caspase-1	1-364	P		MU	Berke et al., 2004
244	caspase-1	1-364	P		MU	Berke et al., 2004
248	caspase-1	1-364	P		MU	Berke et al., 2004