Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P30520

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-456	P		NT	<%Agarwal et al., 2012[]%>
5	glutamyl endopeptidase I	1-22	N		MS	Schilling & Overall, 2008
22	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
45	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
48	matrix metallopeptidase-2	45-59	N		MS	Schilling & Overall, 2008
59	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
140	cathepsin L	133-151	N		MS	Biniossek et al., 2011
164	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
173	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
303	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
324	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
362	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
373	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
403	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
416	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
430	trypsin 1	1-456	N		MS	Schilling & Overall, 2008
433	meprin alpha subunit	2-456	N		MS	Becker-Pauly et al., 2011
433	meprin beta subunit	2-456	N		MS	Becker-Pauly et al., 2011
441	trypsin 1	1-456	N		MS	Schilling & Overall, 2008