Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P29692

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-281	P		NT	<%Agarwal et al., 2012[]%>
24	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
38	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
62	cathepsin L	60-83	N		MS	Biniossek et al., 2011
70	cathepsin K	63-83	N		MS	Schilling & Overall, 2008
72	cathepsin B	60-83	N		MS	Biniossek et al., 2011
83	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
95	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
99	meprin beta subunit	2-281	N		MS	Becker-Pauly et al., 2011
107	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
111	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
117	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
164	meprin beta subunit	2-281	N		MS	Becker-Pauly et al., 2011
200	meprin alpha subunit	2-281	N		MS	Becker-Pauly et al., 2011
210	caspase-7	195-219	N		MS	Schilling & Overall, 2008
219	trypsin 1	2-281	N		MS	Schilling & Overall, 2008
257	granzyme B (Homo sapiens-type)	2-281	N		MS	Van Damme et al., 2010