Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P27694

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-616	P		NT	<%Agarwal et al., 2012[]%>
6	meprin beta subunit	3-16	N		MS	Becker-Pauly et al., 2011
16	trypsin 1	2-616	N		MS	Schilling & Overall, 2008
313	trypsin 1	2-616	N		MS	Schilling & Overall, 2008
324	trypsin 1	2-616	N		MS	Schilling & Overall, 2008
412	trypsin 1	2-616	N		MS	Schilling & Overall, 2008
431	trypsin 1	2-616	N		MS	Schilling & Overall, 2008
541	cathepsin S	514-551	N		MS	Biniossek et al., 2011