Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P26927

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
18	unknown peptidase	1-711	P	release of a signal peptide	NT	Yoshikawa et al., 1999
483	plasma kallikrein	19-711	P			Yoshikawa et al., 1999
483	hepatocyte growth factor activator	19-711	P	conversion to two-chain form	NT	Kawaguchi et al., 2009
483	macrophage-stimulating protein	19-711	P			Skeel & Leonard, 2001