Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P24821

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-1564	P	release of a signal peptide	NT	Siri et al., 1991
64	ADAMTS5 peptidase	23-2201	P			Zhen et al., 2008
70	ADAMTS5 peptidase	23-2201	P			Zhen et al., 2008
89	ADAMTS5 peptidase	23-2201	P			Zhen et al., 2008
98	meprin beta subunit	23-2201	P		NT	Ambort et al., 2009
150	meprin beta subunit	23-2201	P		NT	Ambort et al., 2009
155	matrix metallopeptidase-7	23-2201	P			Siri et al., 1995
1340	matrix metallopeptidase-2	23-2201	P			Siri et al., 1995
1705	matrix metallopeptidase-7	23-2201	P			Siri et al., 1995
1708	meprin beta subunit	23-2201	P		NT	Ambort et al., 2009
1821	meprin beta subunit	23-2201	P		NT	Ambort et al., 2009