Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P24369

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
33	unknown peptidase	1-216	P		NT	<%Agarwal et al., 2012[]%>
49	cathepsin D	34-216	P		MS	Impens et al., 2010
49	cathepsin E	34-216	P		MS	Impens et al., 2010
50	cathepsin E	34-216	P		MS	Impens et al., 2010
100	cathepsin D	34-216	P		MS	Impens et al., 2010
100	cathepsin E	34-216	P		MS	Impens et al., 2010
161	matrix metallopeptidase-2	34-216	N		MS	auf dem Keller et al., 2010