Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P23582

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
23	unknown peptidase	1-126	P		NT	<%Agarwal et al., 2012[]%>
73	unknown peptidase	1-126	P		NT	<%Agarwal et al., 2012[]%>
110	neprilysin	105-126	P			Watanabe et al., 1997
112	neprilysin	105-126	P			Watanabe et al., 1997
114	neprilysin	105-126	P			Watanabe et al., 1997
117	neprilysin	105-126	P			Watanabe et al., 1997
120	neprilysin	105-126	P			Watanabe et al., 1997
123	neprilysin	105-126	P			Watanabe et al., 1997