Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P18583

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-2426	P		NT	<%Agarwal et al., 2012[]%>
153	granzyme B (Homo sapiens-type)	2-2426	N		MS	Van Damme et al., 2010
1640	unknown peptidase		P		MS	Mahrus et al., 2008
1660	cathepsin L	1626-1672	N		MS	Biniossek et al., 2011
1660	cathepsin B	1626-1672	N		MS	Biniossek et al., 2011
1749	granzyme A	1-2426	N			Van Damme et al., 2010
1760	granzyme B (Homo sapiens-type)	2-2426	N		MS	Van Damme et al., 2010
1765	granzyme A	1-2426	N			Van Damme et al., 2010