Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P18075

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
29	unknown peptidase	1-431	P		NT	<%Agarwal et al., 2012[]%>
135	meprin alpha subunit	293-431	N		MS	Becker-Pauly et al., 2011
135	meprin beta subunit	30-431	N		MS	Becker-Pauly et al., 2011
292	unknown peptidase	1-431	P		NT	<%Agarwal et al., 2012[]%>
299	kallikrein-related peptidase 4	1-431	P		CS	Matsumura et al., 2005