Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P17931

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-250	P		NT	<%Agarwal et al., 2012[]%>
62	matrix metallopeptidase-2	2-250	P	normal turnover		Ochieng et al., 1994
62	matrix metallopeptidase-9	2-250	P			Ochieng et al., 1994
62	matrix metallopeptidase-7	2-250	P		NT	Puthenedam et al., 2011
62	membrane-type matrix metallopeptidase-1	2-250	P			Nangia-Makker et al., 2007
76	matrix metallopeptidase-7	2-250	P		NT	Puthenedam et al., 2011
113	matrix metallopeptidase-7	2-250	P		NT	Puthenedam et al., 2011