Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P17858

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-780	P		NT	<%Agarwal et al., 2012[]%>
129	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
144	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
201	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
210	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
345	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
356	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
542	granzyme B (Homo sapiens-type)	2-780	P		MS	Van Damme et al., 2009
698	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
713	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
715	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
718	cathepsin B	716-728	N		MS	Biniossek et al., 2011
726	trypsin 1	2-780	N		MS	Schilling & Overall, 2008