Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P08727

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
72 meprin beta subunit 1-400 N MS Becker-Pauly et al., 2011
113 meprin alpha subunit 1-400 N MS Becker-Pauly et al., 2011
113 meprin beta subunit 1-400 N MS Becker-Pauly et al., 2011
238 granzyme B (Homo sapiens-type) 1-400 N MS Van Damme et al., 2010
280 meprin beta subunit 1-400 N MS Becker-Pauly et al., 2011