Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P08237

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-780	P		NT	<%Agarwal et al., 2012[]%>
56	cathepsin L	48-66	N		MS	Biniossek et al., 2011
119	granzyme B (Homo sapiens-type)	2-780	N		MS	Van Damme et al., 2010
201	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
210	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
543	granzyme B (Homo sapiens-type)	2-780	P		MS	Van Damme et al., 2009
603	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
615	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
699	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
714	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
716	trypsin 1	2-780	N		MS	Schilling & Overall, 2008
727	trypsin 1	2-780	N		MS	Schilling & Overall, 2008