Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P07359

,


Click here to display alignment and conservation of cleavage sites of this sequence with close homologues.  This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
16 unknown peptidase 1-626 P release of a signal peptide NT Titani et al., 1987
291 cathepsin G 17-626 P Pidard et al., 1994
292 cathepsin G 1-626 P Gardiner et al., 2001
298 najalysin 17-626 N Evans, 2004
298 mocarhagin 17-626 N Andrews & Berndt, 2004
312 cathepsin G 17-626 P Pidard et al., 1994