Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P06745

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-558	P		NT	<%Agarwal et al., 2012[]%>
66	cathepsin E	2-558	P		MS	Impens et al., 2010
67	cathepsin E	2-558	P		MS	Impens et al., 2010
68	cathepsin D	2-558	P		MS	Impens et al., 2010
68	cathepsin E	2-558	P		MS	Impens et al., 2010
168	cathepsin D	2-558	P		MS	Impens et al., 2010
169	cathepsin D	2-558	P		MS	Impens et al., 2010
351	cathepsin D	2-558	P		MS	Impens et al., 2010
351	cathepsin E	2-558	P		MS	Impens et al., 2010
406	cathepsin E	2-558	P		MS	Impens et al., 2010
429	cathepsin D	2-558	P		MS	Impens et al., 2010
429	cathepsin E	2-558	P		MS	Impens et al., 2010
430	cathepsin D	2-558	P		MS	Impens et al., 2010
430	cathepsin E	2-558	P		MS	Impens et al., 2010
432	cathepsin D	2-558	P		MS	Impens et al., 2010
433	cathepsin D	2-558	P		MS	Impens et al., 2010
435	cathepsin E	2-558	P		MS	Impens et al., 2010
436	cathepsin D	2-558	P		MS	Impens et al., 2010
436	cathepsin E	2-558	P		MS	Impens et al., 2010
545	cathepsin E	2-558	P		MS	Impens et al., 2010