Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00794

,


Click here to display alignment and conservation of cleavage sites of this sequence with close homologues.  This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
16 unknown peptidase 1-381 P release of a signal peptide NT Harris et al., 1982
43 chymosin 17-381 P NT Pedersen et al., 1979
58 unknown peptidase 1-381 P NT <%Agarwal et al., 2012[]%>
301 chymosin 59-381 P NT Danley et al., 1988
304 chymosin 302-381 P NT Danley et al., 1988