Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00760

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
17	unknown peptidase	1-246	P	release of a signal peptide	NT	Mikes et al., 1966
23	rhizopuspepsin	18-246	N
23	candidapepsin SAP1	18-246	N
23	aspergillopepsin I	18-246	N
23	unknown peptidase	18-246	N
23	acid peptidase (Cladosporium)	18-246	N
23	enteropeptidase	18-246	P			Sadler, 2004
122	trypsin 1	18-246	P	normal turnover		Hubbard et al., 1991
148	trypsin 1	18-246	P	normal turnover		Hubbard et al., 1991