Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00044

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	mitochondrial methionyl aminopeptidase	1-109	P	release of an initiating methionine	NT	Narita & Titani, 1969
5	trypsin 1	1-109	N			Narita et al., 1969
10	trypsin 1	1-109	N			Narita et al., 1969
11	trypsin 1	1-109	N			Narita et al., 1969
19	trypsin 1	1-109	N			Narita et al., 1969
28	trypsin 1	1-109	N			Narita et al., 1969
33	trypsin 1	1-109	N			Narita et al., 1969
44	trypsin 1	1-109	N			Narita et al., 1969
60	trypsin 1	1-109	N			Narita et al., 1969
61	trypsin 1	1-109	N			Narita et al., 1969
79	trypsin 1	1-109	N			Narita et al., 1969
92	trypsin 1	1-109	N			Narita et al., 1969
93	trypsin 1	1-109	N			Narita et al., 1969
95	trypsin 1	1-109	N			Narita et al., 1969
97	trypsin 1	1-109	N			Narita et al., 1969
105	trypsin 1	1-109	N			Narita et al., 1969
106	trypsin 1	1-109	N			Narita et al., 1969