Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00037

,


Click here to display alignment and conservation of cleavage sites of this sequence with close homologues.  This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
1 mitochondrial methionyl aminopeptidase 1-108 P release of an initiating methionine NT Chan & Margoliash, 1966
10 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
13 trypsin 1 1-108 N Chan et al., 1966
15 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
18 trypsin 1 1-108 N Chan et al., 1966
30 trypsin 1 1-108 N Chan et al., 1966
31 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
32 trypsin 1 1-108 N Chan et al., 1966
36 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
38 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
40 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
41 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
43 trypsin 1 1-108 N Chan et al., 1966
44 trypsin 1 1-108 N Chan et al., 1966
51 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
53 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
57 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
58 trypsin 1 1-108 N Chan et al., 1966
60 trypsin 1 1-108 N Chan et al., 1966
64 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
70 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
72 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
73 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
77 trypsin 1 1-108 N Chan et al., 1966
78 trypsin 1 1-108 N Chan et al., 1966
79 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
84 trypsin 1 1-108 N Chan et al., 1966
85 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
87 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
90 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
91 trypsin 1 1-108 N Chan et al., 1966
92 trypsin 1 1-108 N Chan et al., 1966
96 trypsin 1 1-108 N Chan et al., 1966
99 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
102 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
103 chymotrypsin A (cattle-type) 1-108 N Chan et al., 1966
104 trypsin 1 1-108 N Chan et al., 1966