Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00027

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	mitochondrial methionyl aminopeptidase	1-105	P	release of an initiating methionine	NT	Goldstone & Smith, 1967
11	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
27	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
36	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
37	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
47	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
49	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
53	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
60	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
65	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
68	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
75	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
81	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
83	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
86	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
95	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
98	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967
99	chymotrypsin A (cattle-type)	1-105	N			Goldstone et al., 1967