Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P00025

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	mitochondrial methionyl aminopeptidase	1-104	P	release of an initiating methionine	NT	Nakayama et al., 1971
6	trypsin 1	1-104	N			Nakayama et al., 1971
8	trypsin 1	1-104	N			Nakayama et al., 1971
9	trypsin 1	1-104	N			Nakayama et al., 1971
11	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
14	trypsin 1	1-104	N			Nakayama et al., 1971
26	trypsin 1	1-104	N			Nakayama et al., 1971
28	trypsin 1	1-104	N			Nakayama et al., 1971
37	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
39	trypsin 1	1-104	N			Nakayama et al., 1971
47	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
54	trypsin 1	1-104	N			Nakayama et al., 1971
56	trypsin 1	1-104	N			Nakayama et al., 1971
60	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
69	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
73	trypsin 1	1-104	N			Nakayama et al., 1971
75	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
80	trypsin 1	1-104	N			Nakayama et al., 1971
83	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
87	trypsin 1	1-104	N			Nakayama et al., 1971
89	trypsin 1	1-104	N			Nakayama et al., 1971
92	trypsin 1	1-104	N			Nakayama et al., 1971
95	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
98	chymotrypsin A (cattle-type)	1-104	N			Nakayama et al., 1971
100	trypsin 1	1-104	N			Nakayama et al., 1971