Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O88569

,


Click here to display alignment and conservation of cleavage sites of this sequence with close homologues.  This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
27 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
28 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
46 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
66 cathepsin E 1-353 P MS Impens et al., 2010
69 cathepsin D 1-353 P MS Impens et al., 2010
72 cathepsin D 1-353 P MS Impens et al., 2010
72 cathepsin E 1-353 P MS Impens et al., 2010
117 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
118 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
130 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
203 matrix metallopeptidase-2 1-353 N MS auf dem Keller et al., 2010
317 cathepsin E 1-353 P MS Impens et al., 2010