Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O76076

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
23	unknown peptidase	1-250	P	release of a signal peptide	NT	Zhang & Henzel, 2004
177	membrane-type matrix metallopeptidase-1	1-250	P			Overall et al., 2004
183	membrane-type matrix metallopeptidase-1	1-250	P			Overall et al., 2004
215	kallikrein-related peptidase 12	24-250	P		NT	Guillon-Munos et al., 2011