Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O15042

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-1029	P	release of an initiating methionine	MS	Flikka et al., 2006
142	meprin alpha subunit	1-1029	N		MS	Becker-Pauly et al., 2011
142	meprin beta subunit	1-1029	N		MS	Becker-Pauly et al., 2011
522	granzyme B (Homo sapiens-type)	1-1029	N		MS	Van Damme et al., 2010
737	caspase-1	1-1029	N		MS	Agard et al., 2010
950	lysyl endopeptidase (bacteria)	1-1029	N		MS
962	lysyl endopeptidase (bacteria)	1-1029	N		MS