Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence O08736

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
94 caspase-7 1-419 P Rao et al., 2001
132 calpain-2 1-419 P Nakagawa & Yuan, 2000
158 calpain-2 1-419 P Nakagawa & Yuan, 2000
318 caspase-12 1-419 P Fujita et al., 2002
341 caspase-12 1-419 P Rao et al., 2001