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Inhibitors

Peptidase

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MEROPS SUBMISSIONS

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information

Sequence features for peptidase homologue M38.974: dihydropyrimidinase related protein-1

Summary Alignment Tree Sequences Sequence features Distribution Structure

 

MERNUM Species Sequence length Peptidase unit Active site residues Metal ligands Source
MER0689856 Acanthisitta chloris 565 10-404 G325 N66, Y68, Q158, E207, K247 GENBANK:XP_009070958
MER0287418 Alligator mississippiensis 657 315-496 G417 missing, missing, missing, missing, K339 GENBANK:XP_006267379
MER0313740 Alligator sinensis 572 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_006017088
MER0290149 Anas platyrhynchos 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:R0JVB0
MER0290149 Anas platyrhynchos 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:R0JVB0
MER0686298 Apaloderma vittatum 582 27-421 G342 N83, Y85, Q175, E224, K264 GENBANK:XP_009877561
MER0687519 Aptenodytes forsteri 684 129-523 G444 N185, Y187, Q277, E326, K366 GENBANK:XP_009272032
MER0686506 Aquila chrysaetos 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_011589510
MER0556045 Astatotilapia burtoni 676 121-515 S436 N177, C179, Q269, G318, K358 GENBANK:XP_005942674
MER0376587 Astyanax mexicanus 573 18-412 G333 N74, C76, Q166, S215, R255 UNIPROT:W5K915
MER0376587 Astyanax mexicanus 573 18-412 G333 N74, C76, Q166, S215, R255 UNIPROT:W5K915
MER0402338 Balaenoptera acutorostrata 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_007191030
MER0682217 Balearica regulorum 382 1-306 G227 missing, missing, Q60, E109, K149 GENBANK:XP_010298293
MER0680156 Bison bison 613 58-452 S373 N114, Y116, Q206, E255, K295 GENBANK:XP_010846098
MER0432804 Bos grunniens 509 1-348 S269 N10, Y12, Q102, E151, K191 GENBANK:XP_005904381
MER0580502 Bubalus bubalis 572 17-411 S332 N73, Y75, Q165, E214, K254 GENBANK:XP_006051889
MER0678742 Buceros rhinoceros 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_010139750
MER0581625 Calypte anna 291 128-291 missing N184, Y186, Q276, missing, missing GENBANK:XP_008495710
MER0582187 Calypte anna 371 20-210 G131 missing, missing, missing, missing, K53 GENBANK:XP_008494023
MER0677106 Camelus dromedarius 652 97-491 G412 N153, Y155, Q245, E294, K334 GENBANK:XP_010973635
MER0372492 Camelus ferus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_006189108
MER0541318 Capra hircus 509 1-348 S269 N10, Y12, Q102, E151, K191 GENBANK:XP_005681946
MER0675800 Cariama cristata 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A091LZY8
MER0675800 Cariama cristata 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A091LZY8
MER0531147 Ceratotherium simum 687 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004432317
MER0587916 Cercopithecus sabaeus 686 131-525 G446 N187, Y189, Q279, D328, K368 GENBANK:XP_008016134
MER0673362 Chaetura pelagica 639 84-478 G399 N140, Y142, Q232, E281, K321 GENBANK:XP_010001443
MER0672128 Charadrius vociferus 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_009888839
MER0591272 Chelonia mydas 684 129-523 G444 N185, Y187, Q277, E326, K366 GENBANK:XP_007062995
MER0581207 Chinchilla lanigera 572 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_005408877
MER0577374 Chrysemys picta 684 129-523 G444 N185, Y187, Q277, E326, K366 GENBANK:XP_005300326
MER0575364 Chrysochloris asiatica 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_006877368
MER0671205 Colius striatus 424 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_010204288
MER0669080 Colobus angolensis 566 34-235 missing N90, Y92, Q182, F231, missing GENBANK:XP_011790839
MER0579008 Columba livia 680 125-519 G440 N181, Y183, Q273, E322, K362 GENBANK:XP_005501390
MER0574396 Condylura cristata 612 186-451 G372 missing, missing, missing, E192, K232 GENBANK:XP_004681587
MER0572458 Corvus brachyrhynchos 897 342-736 G657 N398, Y400, Q490, E539, K579 GENBANK:XP_008626872
MER0668410 Corvus cornix 569 14-408 G329 N70, Y72, Q162, E211, K251 GENBANK:XP_010400212
MER0590092 Cricetulus griseus 1476 921-1315 G1236 N977, Y979, Q1069, E1118, K1158 GENBANK:XP_007624201
MER0590234 Cricetulus griseus 1615 1060-1454 G1375 N1116, Y1118, Q1208, E1257, K1297 GENBANK:XP_007650098
MER0665532 Cuculus canorus 580 25-419 G340 N81, Y83, Q173, E222, K262 UNIPROT:A0A091GAG7
MER0665532 Cuculus canorus 580 25-419 G340 N81, Y83, Q173, E222, K262 UNIPROT:A0A091GAG7
MER0567285 Cynoglossus semilaevis 670 117-511 A432 N173, C175, Q265, G314, R354 GENBANK:XP_008315216
MER0605976 Dasypus novemcinctus 707 131-548 I474 H187, H189, I279, E356, K396 GENBANK:XP_004447168
MER0606391 Dasypus novemcinctus 573 141-412 G333 missing, missing, Q166, G215, K255 GENBANK:XP_004459503
MER0599649 Echinops telfairi 562 7-401 G322 N63, Y65, Q155, E204, K244 GENBANK:XP_004715113
MER0664147 Egretta garzetta 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_009633797
MER0565572 Elephantulus edwardii 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_006893694
MER0564113 Eptesicus fuscus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_008149107
MER0241093 Equus caballus 624 67-463 C386 N125, Y127, Y219, G268, M308 GENBANK:XP_001917718
MER0561340 Equus przewalskii 348 1-181 G102 missing, missing, missing, missing, K24 GENBANK:XP_008508450
MER0562185 Equus przewalskii 310 18-237 missing N74, Y76, Q166, E215, missing GENBANK:XP_008537393
MER0616280 Erinaceus europaeus 509 1-348 A269 N10, Y12, Q102, A151, K191 GENBANK:XP_007538478
MER0662635 Esox lucius 685 129-523 A444 N185, C187, Q277, S326, K366 GENBANK:XP_010886422
MER0659026 Eurypyga helias 575 20-414 G335 N76, Y78, Q168, E217, K257 GENBANK:XP_010157273
MER0559851 Falco cherrug 643 88-482 G403 N144, Y146, Q236, E285, K325 GENBANK:XP_005433213
MER0545897 Falco peregrinus 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_005243136
MER0545898 Falco peregrinus 690 135-529 G450 N191, Y193, Q283, E332, K372 GENBANK:XP_005243137
MER0610935 Felis catus 641 86-480 G401 N142, Y144, Q234, E283, K323 GENBANK:XP_003985603
MER0569531 Ficedula albicollis 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_005045520
MER0656619 Fukomys damarensis 1742 1187-1581 G1502 N1243, Y1245, Q1335, E1384, K1424 GENBANK:XP_010640104
MER0656620 Fukomys damarensis 909 354-748 G669 N410, Y412, Q502, E551, K591 GENBANK:XP_010640105
MER0654779 Fulmarus glacialis 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A093IT94
MER0654779 Fulmarus glacialis 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A093IT94
MER0558742 Galeopterus variegatus 572 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_008564542
MER0043844 Gallus gallus 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:Q71SG4
MER0043844 Gallus gallus 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:Q71SG4
MER0653687 Gavia stellata 147 4-147 missing N60, Y62, missing, missing, missing GENBANK:XP_009818452
MER0653706 Gavia stellata 412 1-251 G172 missing, missing, Q5, E54, K94 GENBANK:XP_009819277
MER0559633 Geospiza fortis 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_005428114
MER0608766 Gorilla gorilla 572 17-411 S332 N73, Y75, Q165, E214, K254 GENBANK:XP_004038434
MER0653260 Haliaeetus albicilla 573 18-412 G333 N74, Y76, Q166, E215, K255 GENBANK:XP_009919346
MER0652440 Haliaeetus leucocephalus 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_010581766
MER0506942 Heterocephalus glaber 586 30-424 G345 N86, Y88, L178, E227, K267 GENBANK:XP_004885882
MER0592795 Heterocephalus glaber 686 131-525 G446 N187, Y189, L279, E328, K368 GENBANK:XP_004847366
MER0030143 Homo sapiens 572 17-411 G332 N73, Y75, Q165, E214, H289 UNIPROT:Q14194
MER0865752 Hyphomonas beringensis 471 59-132 missing H112, H114, A204, T243, V272 UNIPROT:A0A062UB76
MER0865752 Hyphomonas beringensis 471 59-132 missing H112, H114, A204, T243, V272 UNIPROT:A0A062UB76
MER0612299 Ictidomys tridecemlineatus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_005319032
MER0542286 Jaculus jaculus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_004669892
MER0649057 Larimichthys crocea 676 121-515 A436 N177, C179, Q269, G318, K358 GENBANK:XP_010735976
MER0611809 Latimeria chalumnae 714 127-553 G474 N183, Y185, Q275, E324, K364 GENBANK:XP_006007307
MER0553657 Lepisosteus oculatus 681 126-520 A441 N182, Y184, Q274, S323, K363 GENBANK:XP_006629666
MER0552694 Leptonychotes weddellii 342 1-181 G102 missing, missing, missing, missing, K24 GENBANK:XP_006740142
MER0553020 Leptonychotes weddellii 361 131-345 missing N187, Y189, Q279, E328, missing GENBANK:XP_006744873
MER0549635 Lipotes vexillifer 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_007462521
MER0622205 Loxodonta africana 989 131-828 S749 N187, Y189, missing, E631, K671 GENBANK:XP_003422961
MER0603850 Macaca fascicularis 572 17-411 G332 N73, Y75, Q165, D214, K254 GENBANK:XP_005554506
MER0647367 Manacus vitellinus 682 127-521 G442 N183, Y185, Q275, E324, K364 GENBANK:XP_008919155
MER0646682 Mandrillus leucophaeus 570 15-409 G330 N71, Y73, Q163, D212, K252 GENBANK:XP_011857523
MER0542837 Maylandia zebra 676 121-515 S436 N177, C179, Q269, G318, K358 GENBANK:XP_004564305
MER0623822 Meleagris gallopavo 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_003205985
MER0540902 Melopsittacus undulatus 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_005148555
MER0644159 Merops nubicus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_008943621
MER0642122 Mesitornis unicolor 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A091REY8
MER0642122 Mesitornis unicolor 560 5-399 G320 N61, Y63, Q153, E202, K242 UNIPROT:A0A091REY8
MER0543846 Mesocricetus auratus 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_005068893
MER0538809 Microtus ochrogaster 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_005366008
MER0030138 Mus musculus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:P97427
MER0030138 Mus musculus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:P97427
MER0030138 Mus musculus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:P97427
MER0601545 Mustela putorius 575 117-451 G372 N173, Y175, Q265, missing, missing GENBANK:XP_004770621
MER0601897 Mustela putorius 697 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004801588
MER0563254 Myotis brandtii 600 45-439 G360 N101, Y103, Q193, E242, K282 GENBANK:XP_005864622
MER0613704 Myotis davidii 561 29-400 G321 N85, Y87, Q177, E226, K266 GENBANK:XP_006766651
MER0166179 Myotis lucifugus 104 17-104 missing N73, Y75, missing, missing, missing GENBANK:XP_006107169
MER0175218 Myotis lucifugus 314 13-153 G74 missing, missing, missing, missing, missing GENBANK:XP_006107888
MER0641588 Nannospalax galili 524 57-363 G284 missing, missing, Q117, E166, K206 GENBANK:XP_008852036
MER0535477 Neolamprologus brichardi 375 27-289 missing N59, N61, L151, C232, K272 GENBANK:XP_006793428
MER0535736 Neolamprologus brichardi 676 121-515 S436 N177, C179, Q269, G318, K358 GENBANK:XP_006787353
MER0638420 Nestor notabilis 724 169-563 G484 N225, Y227, Q317, E366, K406 GENBANK:XP_010016515
MER0636602 Nipponia nippon 684 129-523 G444 N185, Y187, Q277, E326, K366 GENBANK:XP_009469398
MER0599992 Nomascus leucogenys 571 17-410 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_003258522
MER0179418 Notothenia coriiceps 676 121-515 A436 N177, C179, Q269, G318, K358 GENBANK:XP_010782914
MER0534058 Ochotona princeps 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004579279
MER0533187 Octodon degus 686 131-525 S446 N187, Y189, Q279, E328, K368 GENBANK:XP_004624635
MER0531240 Odobenus rosmarus 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004413792
MER0633930 Opisthocomus hoazin 704 149-543 G464 N205, Y207, Q297, E346, K386 GENBANK:XP_009934672
MER0529354 Orcinus orca 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004269671
MER0597807 Oreochromis niloticus 679 124-518 S439 N180, C182, Q272, G321, K361 GENBANK:XP_003452246
MER0619057 Ornithorhynchus anatinus 209 1-205 G165 missing, missing, missing, E47, K87 GENBANK:XP_007664056
MER0619763 Ornithorhynchus anatinus 106 4-91 missing N60, Y62, missing, missing, missing GENBANK:XP_001519486
MER0620128 Ornithorhynchus anatinus 137 19-59 missing missing, missing, missing, missing, missing GENBANK:XP_003429989
MER0528593 Orycteropus afer 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_007955693
MER0603008 Oryctolagus cuniculus 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_002724379
MER0619834 Oryzias latipes 687 132-526 S447 N188, C190, Q280, G329, K369 GENBANK:XP_004085348
MER0594833 Otolemur garnettii 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_003800240
MER0619377 Ovis aries 509 1-348 S269 N10, Y12, Q102, E151, K191 GENBANK:XP_004010036
MER0593818 Pan paniscus 566 11-405 G326 N67, Y69, Q159, E208, K248 GENBANK:XP_003816521
MER0624209 Pan troglodytes 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_003310286
MER0624214 Pan troglodytes 683 596-683 missing N652, Y654, missing, missing, missing GENBANK:XP_001174805
MER0519049 Panthera tigris 561 6-400 G321 N62, Y64, Q154, E203, K243 GENBANK:XP_007075854
MER0517049 Pantholops hodgsonii 509 1-348 S269 N10, Y12, Q102, E151, K191 GENBANK:XP_005962201
MER0525762 Papio anubis 447 1-286 G227 missing, missing, Q60, D109, K149 GENBANK:XP_003919628
MER0633024 Pelecanus crispus 147 4-147 missing N60, Y62, missing, missing, missing GENBANK:XP_009481055
MER0633162 Pelecanus crispus 164 1-88 G9 missing, missing, missing, missing, missing GENBANK:XP_009483479
MER0633184 Pelecanus crispus 155 1-155 missing missing, missing, missing, E47, K87 GENBANK:XP_009483907
MER0524808 Pelodiscus sinensis 684 129-523 G444 N185, N187, Q277, E326, K366 UNIPROT:K7FDD7
MER0524808 Pelodiscus sinensis 684 129-523 G444 N185, N187, Q277, E326, K366 UNIPROT:K7FDD7
MER0632163 Phaethon lepturus 559 4-398 G319 N60, Y62, Q152, E201, K241 GENBANK:XP_010291259
MER0631642 Phalacrocorax carbo 631 76-470 G391 N132, Y134, Q224, E273, K313 GENBANK:XP_009512307
MER0520495 Physeter catodon 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_007114892
MER0581115 Picoides pubescens 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:A0A093GLL1
MER0581115 Picoides pubescens 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:A0A093GLL1
MER0522670 Poecilia formosa 676 121-515 A436 N177, C179, Q269, E318, K358 UNIPROT:A0A087YFF1
MER0522670 Poecilia formosa 676 121-515 A436 N177, C179, Q269, E318, K358 UNIPROT:A0A087YFF1
MER0514840 Poecilia reticulata 676 121-515 A436 N177, C179, Q269, E318, K358 GENBANK:XP_008415202
MER0617330 Pongo abelii 40 1-40 missing missing, missing, missing, missing, missing GENBANK:XP_003776473
MER0617331 Pongo abelii 116 1-95 missing missing, missing, missing, E7, K47 GENBANK:XP_002814608
MER0617332 Pongo abelii 168 1-37 missing missing, missing, missing, missing, missing GENBANK:XP_002814609
MER0591795 Pterocles gutturalis 559 4-398 G319 N60, Y62, Q152, E201, K241 GENBANK:XP_010076316
MER0515514 Pteropus alecto 572 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_006919061
MER0594440 Pteropus vampyrus 552 27-391 G312 N57, Y59, K149, G195, R235 GENBANK:XP_011372967
MER0346720 Python bivittatus 567 11-405 G326 N67, S69, Q159, A208, K248 GENBANK:XP_007440165
MER0037363 Rattus norvegicus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:Q62950
MER0037363 Rattus norvegicus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:Q62950
MER0037363 Rattus norvegicus 572 17-411 G332 N73, Y75, Q165, E214, K254 UNIPROT:Q62950
MER0574422 Rhinopithecus roxellana 572 17-411 G332 N73, Y75, Q165, D214, K254 GENBANK:XP_010368353
MER0512484 Saimiri boliviensis 572 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_003934707
MER0621808 Sarcophilus harrisii 659 189-498 G419 missing, missing, Q252, E301, K341 GENBANK:XP_003773444
MER0548279 Serinus canaria 690 135-529 G450 N191, Y193, Q283, E332, K372 GENBANK:XP_009097611
MER0597300 Sorex araneus 1234 679-1073 G994 N735, S737, Q827, E876, K916 GENBANK:XP_004617541
MER0475886 Stegastes partitus 676 121-515 S436 N177, C179, Q269, G318, K358 GENBANK:XP_008274245
MER0495030 Struthio camelus 576 21-415 G336 N77, Y79, Q169, E218, K258 GENBANK:XP_009684531
MER0607799 Sus scrofa 202 1-197 G118 missing, missing, missing, missing, K40 GENBANK:XP_005666576
MER0607800 Sus scrofa 729 200-568 G489 N230, Y232, Q322, E371, K411 GENBANK:XP_003128882
MER0608014 Sus scrofa 233 70-215 missing N126, Y128, missing, missing, missing GENBANK:XP_005658326
MER0201330 synthetic construct 573 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:AAP36144
MER0561563 Taeniopygia guttata 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:H0ZIB9
MER0561563 Taeniopygia guttata 683 128-522 G443 N184, Y186, Q276, E325, K365 UNIPROT:H0ZIB9
MER0595829 Tarsius syrichta 509 1-348 G269 N10, C12, Q102, E151, K191 GENBANK:XP_008064568
MER0347455 Tauraco erythrolophus 529 1-368 G289 N30, Y32, Q122, E171, K211 GENBANK:XP_009976803
MER0472321 Tinamus guttatus 682 127-521 G442 N183, Y185, Q275, E324, K364 GENBANK:XP_010215543
MER0480575 Trichechus manatus 686 131-525 G446 N187, Y189, Q279, E328, K368 GENBANK:XP_004383549
MER0598425 Tupaia chinensis 573 17-411 G332 N73, Y75, Q165, E214, K254 GENBANK:XP_006163257
MER0622906 Tursiops truncatus 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_004319243
MER0452678 Tyto alba 561 6-400 G321 N62, Y64, Q154, E203, K243 GENBANK:XP_009973500
MER0304249 Ursus maritimus 679 124-518 G439 N180, Y182, Q272, E321, K361 GENBANK:XP_008684042
MER0616507 Vicugna pacos 509 1-348 G269 N10, Y12, Q102, E151, K191 GENBANK:XP_006216428
MER0609815 Xenopus tropicalis 680 125-519 G440 N181, Y183, Q273, E322, K362 UNIPROT:Q0V9W2
MER0609815 Xenopus tropicalis 680 125-519 G440 N181, Y183, Q273, E322, K362 UNIPROT:Q0V9W2
MER0453323 Xiphophorus maculatus 676 121-515 A436 N177, C179, Q269, E318, K358 UNIPROT:M4AD17
MER0453323 Xiphophorus maculatus 676 121-515 A436 N177, C179, Q269, E318, K358 UNIPROT:M4AD17
MER0445274 Zonotrichia albicollis 683 128-522 G443 N184, Y186, Q276, E325, K365 GENBANK:XP_005485802

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