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Peptidase

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MEROPS SUBMISSIONS

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information

Sequence features for peptidase homologue M28.974: glutaminyl cyclase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

MERNUM Species Sequence length Peptidase unit Active site residues Metal ligands Source
MER0690171 Acanthisitta chloris 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009076227
MER0622326 Ailuropoda melanoleuca 360 58-360 D141, E200 H139, D158, E201, D247, H329 GENBANK:XP_002914890
MER0265643 Alligator mississippiensis 380 77-380 D160, E220 H158, D178, E221, D267, H349 GENBANK:XP_006270078
MER0311397 Alligator sinensis 380 77-380 D160, E220 H158, D178, E221, D267, H349 GENBANK:XP_006024561
MER0319676 Anas platyrhynchos 301 14-300 D80, E140 H78, D98, E141, D187, H269 GENBANK:XP_005021913
MER0687018 Apaloderma vittatum 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009863508
MER0687139 Aptenodytes forsteri 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009282073
MER0685359 Aquila chrysaetos 363 60-363 D143, E203 H141, D161, E204, D250, H332 GENBANK:XP_011587394
MER0556414 Astatotilapia burtoni 375 64-361 D146, E203 H144, D164, E204, D250, H332 GENBANK:XP_005922417
MER0380164 Astyanax mexicanus 354 48-346 D130, E187 H128, D148, E188, D234, H316 UNIPROT:W5K4E8
MER0380164 Astyanax mexicanus 354 48-346 D130, E187 H128, D148, E188, D234, H316 UNIPROT:W5K4E8
MER0387782 Balaenoptera acutorostrata 447 145-447 D228, E287 H226, D245, E288, D334, H416 GENBANK:XP_007167229
MER0682304 Balearica regulorum 178 1-178 missing, E19 missing, missing, E20, D66, H147 GENBANK:XP_010300104
MER0679421 Bison bison 384 82-384 D165, E224 H163, D182, E225, D271, H353 GENBANK:XP_010836923
MER0422344 Boiga dendrophila 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW2
MER0422344 Boiga dendrophila 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW2
MER0422344 Boiga dendrophila 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW2
MER0422343 Boiga irregularis 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW1
MER0422343 Boiga irregularis 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW1
MER0422343 Boiga irregularis 368 64-367 D146, E207 H144, D164, E208, D254, H336 UNIPROT:A7ISW1
MER0425595 Bombyx mori 338 54-336 D125, E176 H123, D139, E177, D220, H305 GENBANK:XP_004921989
MER0435338 Bos grunniens 392 90-392 D173, E232 H171, D190, E233, D279, H361 GENBANK:XP_005893809
MER0015096 Bos taurus 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:Q28120
MER0015096 Bos taurus 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:Q28120
MER0015096 Bos taurus 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:Q28120
MER0002549 Bothrops jararaca 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q9YIB5
MER0002549 Bothrops jararaca 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q9YIB5
MER0002549 Bothrops jararaca 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q9YIB5
MER0579672 Bubalus bubalis 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_006056896
MER0666284 Buceros rhinoceros 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010142158
MER0617998 Callithrix jacchus 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:F6PIC3
MER0617998 Callithrix jacchus 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:F6PIC3
MER0582106 Calypte anna 299 1-299 D78, E139 H76, D97, E140, D186, H268 GENBANK:XP_008492201
MER0678068 Camelus dromedarius 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_010995551
MER0346721 Camelus ferus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_006181129
MER0530764 Capra hircus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_005686555
MER0675692 Cariama cristata 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009696130
MER0675364 Cerapachys biroi 404 117-401 D188, E237 H186, D202, E238, D285, H370 GENBANK:XP_011333950
MER0533140 Ceratotherium simum 401 99-401 D182, E241 H180, D199, E242, D288, H370 GENBANK:XP_004418191
MER0585221 Cercopithecus sabaeus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_007969123
MER0673455 Chaetura pelagica 294 1-294 D75, E135 H73, D93, E136, D181, H263 GENBANK:XP_010002878
MER0671852 Charadrius vociferus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009878686
MER0585921 Chelonia mydas 379 77-379 D159, E219 H157, D177, E220, D266, H348 GENBANK:XP_007058011
MER0579883 Chinchilla lanigera 395 93-395 D176, E235 H174, D193, E236, D282, H364 GENBANK:XP_005390931
MER0577082 Chrysemys picta 379 77-379 D159, E219 H157, D177, E220, D266, H348 GENBANK:XP_005296295
MER0574551 Chrysochloris asiatica 395 93-395 D176, E235 H174, D193, E236, D282, H364 GENBANK:XP_006839516
MER0666656 Colius striatus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010207651
MER0669100 Colobus angolensis 312 40-312 D93, E152 H91, D110, E153, D199, H281 GENBANK:XP_011791356
MER0669101 Colobus angolensis 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_011791355
MER0578635 Columba livia 364 61-364 D144, E204 H142, D162, E205, D251, H333 GENBANK:XP_005503827
MER0574087 Condylura cristata 357 55-357 D138, E197 H136, D155, E198, D244, H326 GENBANK:XP_004686347
MER0572311 Corvus brachyrhynchos 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_008638067
MER0667854 Corvus cornix 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010390041
MER0664754 Cuculus canorus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009567444
MER0566797 Cynoglossus semilaevis 375 56-354 D138, E195 H136, D156, E196, D242, H324 GENBANK:XP_008311794
MER0605828 Dasypus novemcinctus 347 45-347 D128, E187 H126, D145, E188, D234, H316 GENBANK:XP_004485163
MER0599510 Echinops telfairi 353 50-353 D133, E192 H131, D150, E193, D239, H322 GENBANK:XP_004711226
MER0657435 Egretta garzetta 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009635504
MER0564604 Elephantulus edwardii 496 193-496 D276, E335 H274, D293, E336, D382, H465 GENBANK:XP_006882452
MER0563106 Eptesicus fuscus 362 60-362 D143, E202 H141, D160, E203, D249, H331 GENBANK:XP_008160459
MER0098683 Equus caballus 396 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_001499890
MER0615819 Erinaceus europaeus 315 52-315 D135, E194 H133, D152, E195, D241, H284 GENBANK:XP_007521073
MER0661321 Esox lucius 400 95-400 D178, N240 H176, D201, E241, D287, H369 GENBANK:XP_010897140
MER0662227 Esox lucius 369 59-358 D141, E198 H139, D159, E199, D245, H327 GENBANK:XP_010877495
MER0657094 Eurypyga helias 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010151751
MER0560304 Falco cherrug 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_005445645
MER0545627 Falco peregrinus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_005238668
MER0610871 Felis catus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_003984367
MER0569423 Ficedula albicollis 357 54-357 D136, E197 H134, D154, E198, D244, H326 GENBANK:XP_005043348
MER0657070 Fukomys damarensis 343 41-343 D124, E183 H122, D141, E184, D230, H312 GENBANK:XP_010609732
MER0654673 Fulmarus glacialis 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009574198
MER0557272 Galeopterus variegatus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_008586467
MER0015102 Gallus gallus 233 2-193 D67, E126 H65, D84, E127, missing, missing UNIPROT:O73738
MER0015102 Gallus gallus 233 2-193 D67, E126 H65, D84, E127, missing, missing UNIPROT:O73738
MER0653867 Gavia stellata 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009805276
MER0559151 Geospiza fortis 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_005416296
MER0004032 Gloydius blomhoffi 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q90YA8
MER0004032 Gloydius blomhoffi 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q90YA8
MER0004032 Gloydius blomhoffi 368 63-368 D146, E207 H144, D164, E208, D254, H336 UNIPROT:Q90YA8
MER0608957 Gorilla gorilla 350 48-350 D131, E190 H129, D148, E191, D237, H319 GENBANK:XP_004029166
MER0653334 Haliaeetus albicilla 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009921011
MER0652325 Haliaeetus leucocephalus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010579545
MER0588821 Heterocephalus glaber 472 170-472 D253, E312 H251, D270, E313, D359, H441 GENBANK:XP_004839516
MER0015095 Homo sapiens 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:Q16769
MER0612565 Ictidomys tridecemlineatus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_005336598
MER0547638 Jaculus jaculus 409 107-409 D190, E249 H188, D207, E250, D296, H378 GENBANK:XP_004660240
MER0647855 Larimichthys crocea 400 56-387 D138, E195 H136, D156, E196, D242, H357 GENBANK:XP_010729618
MER0552549 Leptonychotes weddellii 362 60-362 D143, E202 H141, D160, E203, D249, H331 GENBANK:XP_006737519
MER0549222 Lipotes vexillifer 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_007445848
MER0603364 Macaca fascicularis 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_005576166
MER0647044 Manacus vitellinus 297 1-297 D78, E138 H76, D96, E139, D184, H266 GENBANK:XP_008931010
MER0646208 Mandrillus leucophaeus 328 26-328 D109, E168 H107, D126, E169, D215, H297 GENBANK:XP_011823035
MER0542944 Maylandia zebra 375 64-361 D146, E203 H144, D164, E204, D250, H332 GENBANK:XP_004566583
MER0623787 Meleagris gallopavo 354 51-354 D134, E194 H132, D152, E195, D241, H323 GENBANK:XP_003204033
MER0540740 Melopsittacus undulatus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_005146085
MER0644338 Merops nubicus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_008935335
MER0643791 Mesitornis unicolor 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010177128
MER0540317 Microplitis demolitor 348 60-346 D131, E182 H129, D145, E183, D230, H315 GENBANK:XP_008544376
MER0602473 Mustela putorius 362 60-362 D143, E202 H141, D160, E203, D249, H331 UNIPROT:M3YFS3
MER0602473 Mustela putorius 362 60-362 D143, E202 H141, D160, E203, D249, H331 UNIPROT:M3YFS3
MER0563436 Myotis brandtii 343 27-319 D110, E169 H108, D127, E170, D216, H298 GENBANK:XP_005864892
MER0613904 Myotis davidii 401 99-401 D182, E241 H180, D199, E242, D288, H370 UNIPROT:L5MBW1
MER0613904 Myotis davidii 401 99-401 D182, E241 H180, D199, E242, D288, H370 UNIPROT:L5MBW1
MER0241872 Myotis lucifugus 401 99-401 D182, E241 H180, D199, E242, D288, H370 GENBANK:XP_006083512
MER0535031 Neolamprologus brichardi 281 89-267 missing, E109 missing, missing, E110, D156, H238 GENBANK:XP_006800749
MER0638725 Nestor notabilis 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010010847
MER0636193 Nipponia nippon 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009462682
MER0599982 Nomascus leucogenys 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:G1S2M5
MER0599982 Nomascus leucogenys 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:G1S2M5
MER0512990 Notothenia coriiceps 389 77-375 D160, E217 H158, D178, E218, D264, H346 GENBANK:XP_010783655
MER0634416 Notothenia coriiceps 183 9-181 missing, E23 missing, missing, E24, D70, H152 GENBANK:XP_010787652
MER0533401 Octodon degus 300 11-300 D81, E140 H79, D98, E141, D187, H269 GENBANK:XP_004627779
MER0531605 Odobenus rosmarus 362 60-362 D143, E202 H141, D160, E203, D249, H331 GENBANK:XP_004410046
MER0633838 Opisthocomus hoazin 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009932694
MER0529106 Orcinus orca 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_004265096
MER0585949 Oreochromis niloticus 375 64-361 D146, E203 H144, D164, E204, D250, H332 GENBANK:XP_003446267
MER0097766 Ornithorhynchus anatinus 369 67-369 D150, E209 H148, D167, E210, D256, H338 GENBANK:XP_001509099
MER0528178 Orycteropus afer 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_007943256
MER0620748 Oryzias latipes 342 31-329 D113, E170 H111, D131, E171, D217, H299 GENBANK:XP_004082682
MER0594732 Otolemur garnettii 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:H0WL14
MER0594732 Otolemur garnettii 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:H0WL14
MER0015100 Ovis aries 239 5-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O62712
MER0015100 Ovis aries 239 5-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O62712
MER0593839 Pan paniscus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_003817696
MER0624029 Pan troglodytes 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:H2QHR8
MER0624029 Pan troglodytes 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:H2QHR8
MER0519429 Panthera tigris 341 39-341 D122, E181 H120, D139, E182, D228, H310 GENBANK:XP_007082548
MER0517689 Pantholops hodgsonii 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_005978121
MER0526003 Papio anubis 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:A0A096NRF7
MER0526003 Papio anubis 361 59-361 D142, E201 H140, D159, E202, D248, H330 UNIPROT:A0A096NRF7
MER0632794 Pelecanus crispus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009476959
MER0524425 Pelodiscus sinensis 367 65-367 D147, E207 H145, D165, E208, D254, H336 UNIPROT:K7FEB7
MER0524425 Pelodiscus sinensis 367 65-367 D147, E207 H145, D165, E208, D254, H336 UNIPROT:K7FEB7
MER0631823 Phaethon lepturus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010284386
MER0603836 Phalacrocorax carbo 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009500471
MER0520951 Physeter catodon 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_007103440
MER0629715 Picoides pubescens 297 1-297 D78, E137 H76, D95, E138, D184, H266 GENBANK:XP_009899219
MER0609281 Plutella xylostella 348 64-346 D135, E186 H133, D149, E187, D230, H315 GENBANK:XP_011557757
MER0522521 Poecilia formosa 375 63-361 D146, E203 H144, D164, E204, D250, H332 UNIPROT:A0A087XCQ9
MER0522521 Poecilia formosa 375 63-361 D146, E203 H144, D164, E204, D250, H332 UNIPROT:A0A087XCQ9
MER0513060 Poecilia reticulata 375 63-361 D146, E203 H144, D164, E204, D250, H332 GENBANK:XP_008397772
MER0616925 Pongo abelii 384 82-384 D165, E224 H163, D182, E225, D271, H353 GENBANK:XP_002812167
MER0589559 Pterocles gutturalis 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010072825
MER0515344 Pteropus alecto 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_006910458
MER0598199 Pteropus vampyrus 349 59-349 D142, E201 H140, D159, E202, D248, H318 GENBANK:XP_011359729
MER0442908 Python bivittatus 121 1-120 missing, missing missing, missing, missing, D7, H89 GENBANK:XP_007435419
MER0015099 Rattus norvegicus 239 5-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O70288
MER0015099 Rattus norvegicus 239 5-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O70288
MER0555977 Rhinopithecus roxellana 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_010371344
MER0512155 Saimiri boliviensis 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_003926857
MER0621600 Sarcophilus harrisii 369 67-369 D150, E209 H148, D167, E210, D256, H338 UNIPROT:G3W588
MER0621600 Sarcophilus harrisii 369 67-369 D150, E209 H148, D167, E210, D256, H338 UNIPROT:G3W588
MER0547930 Serinus canaria 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009090095
MER0597259 Sorex araneus 351 54-349 D136, E189 H134, D152, E190, D236, H318 GENBANK:XP_004616156
MER0476028 Stegastes partitus 375 64-362 D146, E203 H144, D164, E204, D250, H332 GENBANK:XP_008275082
MER0495138 Struthio camelus 366 64-366 D146, E206 H144, D164, E207, D253, H335 GENBANK:XP_009684933
MER0015107 Sus scrofa 230 2-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O62710
MER0015107 Sus scrofa 230 2-196 D70, E129 H68, D87, E130, missing, missing UNIPROT:O62710
MER0607666 Sus scrofa 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_003481293
MER0608032 Sus scrofa 407 135-407 D218, E295 X216, D235, E296, D342, missing GENBANK:XP_005674414
MER0561231 Taeniopygia guttata 356 54-356 D136, E196 H134, D154, E197, D243, H325 GENBANK:XP_002189357
MER0418108 Tarsius syrichta 328 26-328 D109, E168 H107, D126, E169, D215, H297 GENBANK:XP_008056940
MER0380363 Tauraco erythrolophus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_009977969
MER0199656 Tetraodon nigroviridis 316 19-316 D101, E157 H99, D118, E158, D204, H286 UNIPROT:Q4RP01
MER0199656 Tetraodon nigroviridis 316 19-316 D101, E157 H99, D118, E158, D204, H286 UNIPROT:Q4RP01
MER0474602 Tinamus guttatus 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_010209536
MER0484510 Trichechus manatus 361 59-361 D142, E201 H140, D159, E202, D248, H330 GENBANK:XP_004369610
MER0597639 Tupaia chinensis 360 58-360 D141, E200 H139, D158, E201, D247, H329 GENBANK:XP_006151404
MER0622784 Tursiops truncatus 324 59-324 D142, missing H140, D159, missing, missing, H293 GENBANK:XP_004314042
MER0456484 Tyto alba 272 1-251 D78, E138 H76, D96, E139, D185, missing GENBANK:XP_009963633
MER0233742 Ursus maritimus 363 61-363 D144, E203 H142, D161, E204, D250, H332 GENBANK:XP_008698442
MER0408595 Wasmannia auropunctata 264 5-261 D46, E95 H44, D60, E96, D142, H227 GENBANK:XP_011686771
MER0609368 Xenopus tropicalis 390 60-311 D142, E199 H140, D160, E200, D246, missing GENBANK:XP_004914940
MER0453039 Xiphophorus maculatus 375 63-361 D146, E203 H144, D164, E204, D250, H332 UNIPROT:M4AXK3
MER0453039 Xiphophorus maculatus 375 63-361 D146, E203 H144, D164, E204, D250, H332 UNIPROT:M4AXK3
MER0448652 Zonotrichia albicollis 298 1-298 D78, E138 H76, D96, E139, D185, H267 GENBANK:XP_005492721

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