Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Sequence features for peptidase homologue M12.981: ADAM29 protein

Summary Alignment Tree Sequences Sequence features Distribution Literature

 

MERNUM Species Sequence length Peptidase unit Active site residues Metal ligands Source
MER0268040 Ailuropoda melanoleuca 819 209-395 H342 H341, H345, H351 GENBANK:XP_002922684
MER1220065 Aotus nancymaae 942 198-357 H333 H332, H336, H342 GENBANK:XP_021528474
MER0404953 Balaenoptera acutorostrata 729 195-392 Q128, H334 L127, H333, D131, H337, K137, H343 GENBANK:XP_007192843
MER0679522 Bison bison 711 194-391 H333, Q128 L127, H332, N131, H336, K137, H342 GENBANK:XP_010838564
MER0345477 Bos grunniens 711 209-390 H343 H342, H346, H352 UNIPROT:L8IQS2
MER0345477 Bos grunniens 711 209-390 H343 H342, H346, H352 UNIPROT:L8IQS2
MER0357348 Bos taurus 656 208-396 H342 H341, H345, H351 GENBANK:XP_002707937
MER1220221 Bos taurus 622 199-387 H333 H332, H336, H342 GENBANK:XP_015327879
MER0581409 Bubalus bubalis 728 194-391 Q128, H333 L127, H332, H336, N131, H342, K137 GENBANK:XP_006060336
MER0357366 Callithrix jacchus 928 242-418 H377 H376, H380, H386 GENBANK:XP_003732450
MER1220365 Callithrix jacchus 884 198-374 H333 H332, H336, H342 GENBANK:XP_017825959
MER1220331 Camelus bactrianus 728 200-364 H333 H332, H336, H342 GENBANK:XP_010971558
MER0676987 Camelus dromedarius 728 207-391 Q128, H333, D414 L127, H332, C413, D131, H336, S417, K423, K137, H342 GENBANK:XP_010994708
MER0386531 Camelus ferus 728 207-391 Q128, H333, D414 H332, C413, L127, D131, H336, S417, K137, H342, K423 GENBANK:XP_006189619
MER0829355 Camelus ferus 322 156-294 H288 H287, H291, V297 UNIPROT:S9Y092
MER0829355 Camelus ferus 322 156-294 H288 H287, H291, V297 UNIPROT:S9Y092
MER0168061 Canis lupus familiaris 1036 364-552 H497 H496, H500, H506 GENBANK:XP_003433407
MER0546832 Capra hircus 728 194-391 Q128, H333 L127, H332, N131, H336, K137, H342 GENBANK:XP_005683630
MER1220245 Castor canadensis 761 206-372 H341 H340, H344, H350 GENBANK:XP_020010801
MER0270856 Cavia porcellus 770 207-367 H343 H342, H346, H352 GENBANK:XP_003469226
MER1221022 Cavia porcellus 789 207-367 H343 H342, H346, H352 GENBANK:XP_023420577
MER1220937 Cebus capucinus 929 198-356 H333 H332, H336, H342 GENBANK:XP_017354030
MER0374266 Ceratotherium simum 896 194-389 Q833, Q128, H333 H332, L832, L127, H336, D836, N131, K137, H342, E842 GENBANK:XP_004444118
MER1221360 Cercocebus atys 845 198-386 H333, H332, H336, H342, GENBANK:XP_011941742
MER0584793 Cercopithecus sabaeus 818 194-389 Q128, H333, D412 H332, C411, L127, H336, P415, D131, H342, K421, K137 GENBANK:XP_007998486
MER0582877 Chinchilla lanigera 808 203-398 H342 H341, H345, H351 GENBANK:XP_005373585
MER0575779 Chrysochloris asiatica 803 177-390 E333 H332, H336, H342 GENBANK:XP_006864606
MER0670836 Colobus angolensis 750 194-389 Q128, H333 L127, H332, D131, H336, K137, H342 GENBANK:XP_011815186
MER1220510 Dipodomys ordii 749 199-376 H334 H333, H337, H343 GENBANK:XP_012879221
MER1219469 Enhydra lutris 865 209-383 H342 H341, H345, H351 GENBANK:XP_022367641
MER0564347 Eptesicus fuscus 771 191-386 Q125, H330 L124, H329, D128, H333, K134, H339 GENBANK:XP_008153475
MER1219109 Equus asinus 793 215-392 H348 H347, H351, H357 GENBANK:XP_014697617
MER0098537 Equus caballus 785 201-396 H340 H339, H343, H349 GENBANK:XP_001496199
MER1219149 Equus caballus 793 215-392 H348 H347, H351, H357 GENBANK:XP_023492041
MER0562700 Equus przewalskii 793 209-404 Q145, H348 L144, H347, H351, S148, H357, E154 GENBANK:XP_008541100
MER0616294 Erinaceus europaeus 747 194-389 Q128, H333 L127, H332, D131, H336, K137, H342 GENBANK:XP_007538568
MER0346210 Felis catus 745 200-377 H333 H332, H336, H342 GENBANK:XP_004001485
MER0651737 Fukomys damarensis 742 203-398 Q137, H342 L136, H341, H345, Y140, H351, M146 GENBANK:XP_010628195
MER0558745 Galeopterus variegatus 839 250-443 Q184, H389 H388, L183, H392, G187, K193, H398 GENBANK:XP_008564558
MER0344932 Gorilla gorilla 908 198-386 H333 H332, H336, H342 GENBANK:XP_004040702
MER1221184 Hipposideros armiger 723 199-357 H333 H332, H336, H342 GENBANK:XP_019491668
MER0006267 Homo sapiens 820 194-389 H333 H332, H336, H342 GENBANK:AAI66695
MER0006267 Homo sapiens 820 194-389 H333 H332, H336, H342 GENBANK:AAI66695
MER0006267 Homo sapiens 820 194-389 H333 H332, H336, H342 GENBANK:AAI66695
MER0006267 Homo sapiens 820 194-389 H333 H332, H336, H342 GENBANK:AAI66695
MER0612920 Ictidomys tridecemlineatus 787 203-397 E137, H342 H341, L136, H345, N140, M146, H351 GENBANK:XP_005325599
MER0548538 Lipotes vexillifer 715 194-391 Q128, H333 L127, H332, D131, H336, K137, H342 GENBANK:XP_007471187
MER0258320 Loxodonta africana 855 261-438 E395 H394, H398, H404 GENBANK:XP_003415896
MER1220247 Loxodonta africana 797 203-380 E337 H336, H340, H346 GENBANK:XP_010593953
MER0091093 Macaca fascicularis 827 194-389 H333 H332, H336, H342 UNIPROT:Q4R3D7
MER0091093 Macaca fascicularis 827 194-389 H333 H332, H336, H342 UNIPROT:Q4R3D7
MER0172405 Macaca mulatta 845 194-389 H333 H332, H336, H342 GENBANK:XP_001088195
MER0645896 Mandrillus leucophaeus 845 194-389 Q128, H333 H332, L127, H336, D131, K137, H342 GENBANK:XP_011850515
MER1219780 Marmota marmota 787 207-396 H342 H341, H345, H351 GENBANK:XP_015341490
MER1220910 Microcebus murinus 781 198-377 H333 H332, H336, H342 GENBANK:XP_012626152
MER1220830 Miniopterus natalensis 825 195-357 H333 H332, H336, H342 GENBANK:XP_016055736
MER0571948 Myotis brandtii 759 194-389 Q128, H333 L127, H332, D131, H336, H342, K137 GENBANK:XP_005882760
MER0613460 Myotis davidii 748 194-389 Q128, H333 L127, H332, H336, D131, H342, K137 GENBANK:XP_006770805
MER0237156 Myotis lucifugus 770 194-389 Q128, H333 L127, H332, H336, D131, H342, K137 UNIPROT:G1Q0Q4
MER0237156 Myotis lucifugus 770 194-389 Q128, H333 L127, H332, H336, D131, H342, K137 UNIPROT:G1Q0Q4
MER0188214 Nomascus leucogenys 864 280-424 E407 E406, E410, L416 GENBANK:XP_003258076
MER0534043 Ochotona princeps 749 199-392 H137, H338 H337, L136, H341, N140, M146, H347 GENBANK:XP_004579323
MER0534045 Ochotona princeps 684 199-392 H137, H338 L136, H337, H341, N140, H347, M146 GENBANK:XP_004579324
MER1220722 Ochotona princeps 752 203-382 H338 H337, H341, H347 GENBANK:XP_012786846
MER0532367 Octodon degus 810 194-389 Q128, H333, D412 H332, C411, L127, H336, A415, N131, H342, E421, M137 GENBANK:XP_004640307
MER1220319 Odocoileus virginianus 737 208-388 H342 H341, H345, H351 GENBANK:XP_020732847
MER0529885 Orcinus orca 722 194-391 Q128, H333 H332, L127, D131, H336, K137, H342 GENBANK:XP_004278747
MER0528773 Orycteropus afer 751 194-385 E333, Q128 L127, H332, D131, H336, K137, H342 GENBANK:XP_007948549
MER0357477 Oryctolagus cuniculus 755 203-393 H338 H337, H341, H347 GENBANK:XP_002709369
MER0603191 Oryctolagus cuniculus 737 199-393 Y137, H338 L136, H337, N140, H341, M146, H347 GENBANK:XP_008248172
MER1221164 Otolemur garnettii 809 207-395 H342 H341, H345, H351 GENBANK:XP_023370685
MER0345452 Ovis aries 737 211-399 H345 H344, H348, H354 GENBANK:XP_004005386
MER0357307 Pan paniscus 943 251-439 H386 H385, H389, H395 GENBANK:XP_003823553
MER1219685 Pan paniscus 890 198-386 H333 H332, H336, H342 GENBANK:XP_008975325
MER0357312 Pan troglodytes 935 198-377 H333 H332, H336, H342 UNIPROT:G2HEY7
MER0357312 Pan troglodytes 935 198-377 H333 H332, H336, H342 UNIPROT:G2HEY7
MER0518588 Panthera tigris 772 203-398 Q137, H342 H341, L136, H345, D140, H351, E146 GENBANK:XP_007097260
MER0517647 Pantholops hodgsonii 728 194-391 Q128, H333 H332, L127, N131, H336, K137, H342 GENBANK:XP_005977621
MER0345891 Papio anubis 845 198-386 H333 H332, H336, H342 GENBANK:XP_003899425
MER0519779 Physeter catodon 728 194-391 Q128, H333 L127, H332, D131, H336, H342, K137 GENBANK:XP_007128202
MER1220026 Piliocolobus tephrosceles 839 198-386 H333 H332, H336, H342 GENBANK:XP_023082548
MER0357303 Pongo abelii 863 198-386 H333 H332, H336, H342 GENBANK:XP_002832847
MER1219617 Pongo abelii 785 198-386 H333 H332, H336, H342 GENBANK:PNJ24077
MER0346835 Pteropus alecto 648 200-357 H333 H332, H336, H342 GENBANK:ELK17545
MER0515994 Pteropus alecto 315 1-91 missing missing, missing, missing GENBANK:XP_006925298
MER0597937 Pteropus vampyrus 584 167-362 Q101, H306 L100, H305, H309, N104, H315, K110 GENBANK:XP_011358642
MER1220275 Rhinolophus sinicus 923 206-384 H340 H339, H343, H349 GENBANK:XP_019588637
MER1219917 Rhinopithecus bieti 827 198-386 H333 H332, H336, H342 GENBANK:XP_017734625
MER0569765 Rhinopithecus roxellana 845 194-389 H333 H332, H336, H342 GENBANK:XP_010382383
MER0345242 Saimiri boliviensis 888 198-374 H333 H332, H336, H342 GENBANK:XP_003933927
MER1220090 Saimiri boliviensis 833 198-374 H333 H332, H336, H342 GENBANK:XP_010342733
MER0179693 Sus scrofa 722 194-391 H333 H332, H336, H342 GENBANK:XP_001927636
MER0596618 Tarsius syrichta 775 194-389 Q128, H333 H332, L127, H336, D131, K137, H342 GENBANK:XP_008047118
MER1220873 Trichechus manatus 813 208-385 E342 H341, H345, H351 GENBANK:XP_023598687
MER0598145 Tupaia chinensis 751 199-394 Q137, Y338 F136, H337, G140, H341, Q146, H347 GENBANK:XP_006165600
MER0622864 Tursiops truncatus 722 194-391 Q128, H333 L127, H332, D131, H336, K137, H342 GENBANK:XP_004317423
MER0146128 Ursus maritimus 957 203-395 Q137, H342 H341, L136, D140, H345, K146, H351 GENBANK:XP_008703288

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use