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Peptidase

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MEROPS SUBMISSIONS

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information

Sequence features for peptidase M12.248: peptidase similar to ADAMTS-6 peptidase (Mus musculus-type)

Summary Alignment Tree Sequences Sequence features Distribution

 

MERNUM Species Sequence length Peptidase unit Active site residues Metal ligands Source
MER1221256 Acanthaster planci 1135 270-482 E422 H421, H425, H431 GENBANK:XP_022087716
MER0269964 Ailuropoda melanoleuca 1126 253-476 E412, P907 E906, H411, P910, H415, H421, D916 GENBANK:XP_002919349
MER0288555 Alligator mississippiensis 1119 247-470 E406 H405, H409, H415 GENBANK:XP_006259120
MER0293029 Alligator sinensis 1119 247-470 E406 H405, H409, H415 GENBANK:XP_006034788
MER0334618 Anas platyrhynchos 1119 246-464 R406 H405, H409, H415 GENBANK:XP_005013029
MER0225277 Anolis carolinensis 1105 249-468 E404 H403, H407, H413 GENBANK:XP_003216337
MER0687637 Apaloderma vittatum 458 246-458 E405 H404, H408, H414 GENBANK:XP_009864016
MER0625256 Aplysia californica 454 1-58 missing missing, missing, H3 GENBANK:XP_005113307
MER0687466 Aptenodytes forsteri 1118 246-469 E405 H404, H408, H414 GENBANK:XP_009270766
MER0685332 Aquila chrysaetos 1119 247-470 E406 H405, H409, H415 GENBANK:XP_011586848
MER0556230 Astatotilapia burtoni 1123 251-474 E410 H409, H413, H419 GENBANK:XP_005945767
MER0364840 Astyanax mexicanus 1002 130-353 E289 H288, H292, H298 GENBANK:XP_007255098
MER0398193 Balaenoptera acutorostrata 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007176095
MER0608470 Balearica regulorum 779 17-130 E66 H65, H69, H75 GENBANK:XP_010309264
MER0680091 Bison bison 1067 245-468 E404 H403, H407, H413 GENBANK:XP_010843828
MER0680092 Bison bison 1117 245-468 E404 H403, H407, H413 GENBANK:XP_010843826
MER0434976 Bos grunniens 1117 245-468 E404 H403, H407, H413 UNIPROT:L8IQ76
MER0434976 Bos grunniens 1117 245-468 E404 H403, H407, H413 UNIPROT:L8IQ76
MER0167551 Bos taurus 1117 249-468 E404 H403, N408, H413 GENBANK:XP_870614
MER1219532 Branchiostoma belcheri 863 18-201 E138 H137, H141, H147 GENBANK:XP_019634540
MER0137782 Branchiostoma floridae 972 82-300 E237 H236, H240, H246 GENBANK:EEA72915
MER0581017 Bubalus bubalis 1118 246-469 E405 H404, H408, H414 GENBANK:XP_006074200
MER0678532 Buceros rhinoceros 780 94-317 E253 H252, H256, H262 GENBANK:XP_010130199
MER0357522 Callithrix jacchus 1117 249-468 E404 H403, H407, H413 UNIPROT:F7HYN4
MER0357522 Callithrix jacchus 1117 249-468 E404 H403, H407, H413 UNIPROT:F7HYN4
MER0828912 Callithrix jacchus 860 269-420 E404 H403, H407, H413 GENBANK:-
MER0568106 Calypte anna 1118 246-469 E405 H404, H408, H414 GENBANK:XP_008501667
MER0677090 Camelus dromedarius 1117 245-468 E404 H403, H407, H413 GENBANK:XP_010973222
MER0522573 Camelus ferus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_006186146
MER0602341 Canis lupus familiaris 1117 245-468 E404 H403, H407, H413 UNIPROT:E2QXE2
MER0602341 Canis lupus familiaris 1117 245-468 E404 H403, H407, H413 UNIPROT:E2QXE2
MER0344985 Capitella teleta 1115 222-435 E371 H370, H374, H380 UNIPROT:R7UR77
MER0344985 Capitella teleta 1115 222-435 E371 H370, H374, H380 UNIPROT:R7UR77
MER0345584 Capitella teleta 657 202-423 E359 H358, H362, H368 UNIPROT:R7TSA1
MER0345584 Capitella teleta 657 202-423 E359 H358, H362, H368 UNIPROT:R7TSA1
MER0551941 Capra hircus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_005694695
MER0537466 Ceratotherium simum 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004422927
MER0585722 Cercopithecus sabaeus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007972071
MER0673519 Chaetura pelagica 1119 247-470 E406 H405, H409, H415 GENBANK:XP_010003666
MER0671801 Charadrius vociferus 808 1-159 E95 H94, H98, H104 GENBANK:XP_009893813
MER0672469 Charadrius vociferus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_009884392
MER0591077 Chelonia mydas 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007059053
MER0583569 Chinchilla lanigera 1118 246-469 E405 H404, H408, H414 GENBANK:XP_005392689
MER0575267 Chrysochloris asiatica 1014 142-365 E301 H300, H304, H310 GENBANK:XP_006875360
MER0045277 Ciona intestinalis 1208 332-553 E489 H488, H492, H498 GENBANK:XP_002127703
MER0829356 Ciona savignyi 1095 194-351 E328 H327, H331, H337 UNIPROT:H2YPL9
MER0829578 Ciona savignyi 816 41-144 E121 H120, H124, H130 UNIPROT:H2YPM0
MER0829738 Ciona savignyi 1032 123-305 E282 H281, H285, H291 UNIPROT:H2YPL8
MER0671211 Colius striatus 908 36-259 E195 H194, H198, H204 GENBANK:XP_010204381
MER0669352 Colobus angolensis 738 1-89 E25 H24, H28, H34 GENBANK:XP_011785515
MER0578758 Columba livia 1118 246-469 E405 H404, H408, H414 GENBANK:XP_005506024
MER0574235 Condylura cristata 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004678324
MER0572352 Corvus brachyrhynchos 1118 246-469 E405 H404, H408, H414 GENBANK:XP_008641767
MER0667974 Corvus cornix 738 1-89 E25 H24, H28, H34 GENBANK:XP_010393627
MER0345838 Crassostrea gigas 1101 235-450 E385 H384, H388, H394 UNIPROT:K1RVI0
MER0345838 Crassostrea gigas 1101 235-450 E385 H384, H388, H394 UNIPROT:K1RVI0
MER1220110 Crassostrea virginica 1106 241-455 E390 H389, H393, H399 GENBANK:XP_022313706
MER0357502 Cricetulus griseus 1117 249-468 E404 H403, H407, H413 GENBANK:XP_003507981
MER0664933 Cuculus canorus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_009557878
MER0568213 Cynoglossus semilaevis 1132 260-483 E419 H418, H422, H428 GENBANK:XP_008323759
MER0829059 Danio rerio 1116 268-423 E403 H402, H406, H412 GENBANK:-
MER0829540 Danio rerio 1117 268-424 E404 H403, H407, H413 GENBANK:-
MER1221185 Danio rerio 644 248-467 E403 H402, H406, H412 GENBANK:XP_021334950
MER0605808 Dasypus novemcinctus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_004465633
MER0605809 Dasypus novemcinctus 576 246-469 E405 H404, H408, H414 GENBANK:XP_004465636
MER0605810 Dasypus novemcinctus 590 246-469 E405 H404, H408, H414 GENBANK:XP_004465635
MER0599145 Echinops telfairi 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004703631
MER0522446 Egretta garzetta 1118 246-469 E405 H404, H408, H414 GENBANK:XP_009645174
MER0565325 Elephantulus edwardii 1117 245-468 E404 H403, H407, H413 GENBANK:XP_006899427
MER0563094 Eptesicus fuscus 1114 241-464 E400 H399, H403, H409 GENBANK:XP_008160088
MER0098442 Equus caballus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_001492944
MER0561176 Equus przewalskii 1117 245-468 E404 H403, H407, H413 GENBANK:XP_008521828
MER0661666 Esox lucius 1170 273-496 E432 H431, H435, H441 GENBANK:XP_010862076
MER1221121 Esox lucius 1145 277-496 E432 H431, H435, H441 GENBANK:XP_012992469
MER0559835 Falco cherrug 1119 247-470 E406 H405, H409, H415 GENBANK:XP_005432747
MER0545742 Falco peregrinus 1119 247-470 E406 H405, H409, H415 GENBANK:XP_005240703
MER0346158 Felis catus 1117 249-468 E404 H403, H407, H413 GENBANK:XP_003981062
MER0569856 Ficedula albicollis 1118 246-469 E405 H404, H408, H414 GENBANK:XP_005060746
MER0655698 Fukomys damarensis 807 7-116 E52 H51, H55, H61 GENBANK:XP_010635647
MER0829871 Fukomys damarensis 751 19-73 E52 H51, H55, H61 UNIPROT:A0A091D9L1
MER0829871 Fukomys damarensis 751 19-73 E52 H51, H55, H61 UNIPROT:A0A091D9L1
MER0557661 Galeopterus variegatus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_008565981
MER0606887 Gallus gallus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_004937336
MER0606889 Gallus gallus 1003 247-470 E406 H405, H409, H415 GENBANK:XP_004937337
MER0559712 Geospiza fortis 1119 247-470 E406 H405, H409, H415 GENBANK:XP_005429354
MER0346057 Gorilla gorilla 1117 249-468 E404 H403, H407, H413 UNIPROT:G3RJ61
MER0346057 Gorilla gorilla 1117 249-468 E404 H403, H407, H413 UNIPROT:G3RJ61
MER0653342 Haliaeetus albicilla 505 246-469 E405 H404, H408, H414 GENBANK:XP_009921127
MER0652297 Haliaeetus leucocephalus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_010578833
MER0504480 Heterocephalus glaber 645 246-469 E405 H404, H408, H414 GENBANK:XP_004884427
MER0594425 Heterocephalus glaber 1118 246-469 E405 H404, H408, H414 GENBANK:XP_004862932
MER0547165 Jaculus jaculus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004671258
MER0650225 Larimichthys crocea 639 248-463 G405 G405, G405, H408 GENBANK:XP_010752321
MER0553483 Lepisosteus oculatus 1121 249-472 E408 H407, H411, H417 GENBANK:XP_006627092
MER0546485 Leptonychotes weddellii 977 245-468 E404 H403, H407, H413 GENBANK:XP_006732603
MER1221404 Leptosomus discolor 612 251-470 E406 H405, H409, H415 GENBANK:XP_009951942
MER1219437 Limulus polyphemus 711 191-409 E345 H344, H348, H354 GENBANK:XP_022240084
MER0548986 Lipotes vexillifer 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007457174
MER0829658 Lottia gigantea 1077 208-378 E360 H359, H363, H369 UNIPROT:V4A015
MER0829658 Lottia gigantea 1077 208-378 E360 H359, H363, H369 UNIPROT:V4A015
MER0357774 Macaca fascicularis 763 15-114 E50 H49, H53, H59 UNIPROT:G7P7M0
MER0357774 Macaca fascicularis 763 15-114 E50 H49, H53, H59 UNIPROT:G7P7M0
MER0127127 Macaca mulatta 1117 245-468 E404 H403, H407, H413 GENBANK:XP_001084793
MER0829163 Macaca mulatta 858 268-422 E404 H403, H407, H413 UNIPROT:F7ECB0
MER0647588 Manacus vitellinus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_008922945
MER0646865 Mandrillus leucophaeus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_011822151
MER0542955 Maylandia zebra 1123 251-474 E410 H409, H413, H419 GENBANK:XP_004566944
MER0829822 Meleagris gallopavo 752 1-53 E32 H31, H35, H41 UNIPROT:G3URR6
MER0541151 Melopsittacus undulatus 1118 246-469 E405 H404, H408, H414 GENBANK:XP_005151972
MER1221257 Meriones unguiculatus 519 249-468 E404 H403, H407, H413 GENBANK:XP_021505110
MER0644135 Merops nubicus 541 246-469 E405 H404, H408, H414 GENBANK:XP_008939374
MER0545176 Mesocricetus auratus 1011 245-468 E404 H403, H407, H413 GENBANK:XP_005065538
MER0538845 Microtus ochrogaster 1117 245-468 E404 H403, H407, H413 GENBANK:XP_005366642
MER1221377 Miniopterus natalensis 1116 248-467 E403 H402, H406, H412 GENBANK:XP_016054250
MER1220045 Mizuhopecten yessoensis 1154 284-498 E433 H432, H436, H442 GENBANK:XP_021359804
MER0188234 Monodelphis domestica 1118 246-469 E405 H404, H408, H414 GENBANK:XP_001366544
MER0026931 Mus musculus 1117 245-468 E404 H403, H407, H413 UNIPROT:D3Z1A5
MER0026931 Mus musculus 1117 245-468 E404 H403, H407, H413 UNIPROT:D3Z1A5
MER0602434 Mustela putorius 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004764606
MER0602436 Mustela putorius 1067 245-468 E404 H403, H407, H413 GENBANK:XP_004764608
MER0602438 Mustela putorius 973 245-468 E404 H403, H407, H413 GENBANK:XP_004764609
MER0576928 Myotis brandtii 1115 242-465 E401 H400, H404, H410 GENBANK:XP_005857996
MER1220660 Myotis brandtii 1138 245-464 E400 H399, H403, H409 GENBANK:XP_014404481
MER0346836 Myotis davidii 952 198-372 E357 H356, H360, H360 UNIPROT:L5LYV1
MER0346836 Myotis davidii 952 198-372 E357 H356, H360, H360 UNIPROT:L5LYV1
MER1220673 Myotis lucifugus 1114 245-464 E400 H399, H403, H409 GENBANK:XP_014307909
MER0638968 Nannospalax galili 1118 246-469 E405 H404, H408, H414 GENBANK:XP_008854389
MER0534705 Neolamprologus brichardi 1123 251-474 E410 H409, H413, H419 GENBANK:XP_006804802
MER0638724 Nestor notabilis 457 246-457 E405 H404, H408, H414 GENBANK:XP_010010781
MER0634409 Notothenia coriiceps 827 260-483 E419 H418, H422, H428 GENBANK:XP_010787360
MER0533752 Ochotona princeps 1120 245-457 E404 H403, H407, H413 GENBANK:XP_004583870
MER0533113 Octodon degus 1061 246-469 E405 H404, H408, H414 GENBANK:XP_004623266
MER0531758 Odobenus rosmarus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004402292
MER0357335 Oikopleura dioica 1151 237-452 E386 H385, H389, H395 UNIPROT:E4YH14
MER0357335 Oikopleura dioica 1151 237-452 E386 H385, H389, H395 UNIPROT:E4YH14
MER0829826 Ophiophagus hannah 893 346-503 E482 H481, H485, H491 UNIPROT:V8P507
MER0829826 Ophiophagus hannah 893 346-503 E482 H481, H485, H491 UNIPROT:V8P507
MER0633731 Opisthocomus hoazin 1118 246-469 E405 H404, H408, H414 GENBANK:XP_009942011
MER0529429 Orcinus orca 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004270794
MER0357523 Oreochromis niloticus 1123 255-474 E410 H409, H413, H419 GENBANK:XP_003455202
MER0097886 Ornithorhynchus anatinus 903 246-469 E405 H404, H408, H414 GENBANK:XP_001513889
MER0528932 Orycteropus afer 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007951044
MER0110091 Oryctolagus cuniculus 1116 248-467 E403 H402, H406, H412 UNIPROT:G1SFL4
MER0110091 Oryctolagus cuniculus 1116 248-467 E403 H402, H406, H412 UNIPROT:G1SFL4
MER0357469 Otolemur garnettii 1117 249-468 E404 H403, H407, H413 UNIPROT:H0X3E9
MER0357469 Otolemur garnettii 1117 249-468 E404 H403, H407, H413 UNIPROT:H0X3E9
MER0346184 Ovis aries 1117 249-468 E404 H403, H407, H413 GENBANK:XP_004016986
MER0357505 Pan paniscus 1117 249-468 E404 H403, H407, H413 GENBANK:XP_003827475
MER0357510 Pan troglodytes 1117 249-468 E404 H403, H407, H413 UNIPROT:H2R5K7
MER0357510 Pan troglodytes 1117 249-468 E404 H403, H407, H413 UNIPROT:H2R5K7
MER0519326 Panthera tigris 1117 245-468 E404 H403, H407, H413 GENBANK:XP_007079962
MER0517362 Pantholops hodgsonii 1117 245-468 E404 H403, H407, H413 GENBANK:XP_005972009
MER0347698 Papio anubis 407 249-407 E404 H403, H407, missing GENBANK:XP_003899792
MER0525800 Papio anubis 761 53-112 missing missing, missing, H57 GENBANK:XP_003899782
MER1221271 Patagioenas fasciata 577 251-470 E406 H405, H409, H415 GENBANK:OPJ90547
MER0633316 Pelecanus crispus 542 247-470 E406 H405, H409, H415 GENBANK:XP_009486271
MER0519857 Physeter catodon 423 21-134 E70 H69, H73, H79 GENBANK:XP_007120140
MER0629836 Picoides pubescens 804 45-155 E91 H90, H94, H100 GENBANK:XP_009901306
MER0521413 Poecilia formosa 1121 258-472 E408 H407, H411, H417 GENBANK:XP_007570859
MER0513720 Poecilia reticulata 1121 249-472 E408 H407, H411, H417 GENBANK:XP_008421602
MER0357773 Pongo abelii 782 34-133 E69 H68, H72, H78 GENBANK:XP_002815648
MER0590141 Pterocles gutturalis 602 1-182 E118 H117, H121, H127 GENBANK:XP_010073631
MER0346027 Pteropus alecto 975 177-396 E332 H331, H335, H341 UNIPROT:L5KKW7
MER0346027 Pteropus alecto 975 177-396 E332 H331, H335, H341 UNIPROT:L5KKW7
MER0440249 Python bivittatus 1119 247-470 E406 H405, H409, H415 GENBANK:XP_007420181
MER0188216 Rattus norvegicus 1164 249-468 E404 H403, H407, H413 GENBANK:XP_003753577
MER0357511 Rattus norvegicus 1117 249-468 E404 H403, H407, H413 GENBANK:XP_003749223
MER0555769 Rhinopithecus roxellana 1117 245-468 E404 H403, H407, H413 GENBANK:XP_010366583
MER0357460 Saccoglossus kowalevskii 1107 239-457 E393 H392, H396, H402 GENBANK:XP_002736385
MER0346130 Saimiri boliviensis 1015 147-366 E302 H301, H305, H311 GENBANK:XP_003926002
MER1221406 Salmo salar 1121 250-469 E405, H404, H408, H414, GENBANK:XP_013994031
MER0357504 Sarcophilus harrisii 1099 250-469 E405 H404, H408, H414 GENBANK:XP_003759452
MER0550957 Serinus canaria 1119 247-470 E406 H405, H409, H415 GENBANK:XP_009096426
MER0597512 Sorex araneus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004608535
MER0468754 Stegastes partitus 602 258-481 E417 H416, H420, H426 GENBANK:XP_008299052
MER0176553 Strongylocentrotus purpuratus 1320 363-584 E524 H523, H527, H533 GENBANK:XP_001180742
MER0513959 Struthio camelus 1119 247-470 E406 H405, H409, H415 GENBANK:XP_009677453
MER0357535 Sus scrofa 970 102-321 E257 H256, H260, H266 GENBANK:XP_003134060
MER0829359 Takifugu rubripes 827 284-438 E419 H418, H422, H428 UNIPROT:H2VD19
MER0596658 Tarsius syrichta 644 245-468 E404 H403, H407, H413 GENBANK:XP_008047971
MER0829218 Tetraodon nigroviridis 1095 238-395 E375 H374, H378, H384 GENBANK:-
MER0474066 Tinamus guttatus 988 152-375 E311 H310, H314, H320 GENBANK:XP_010226544
MER0483101 Tinamus guttatus 458 247-458 E406 H405, H409, H415 GENBANK:XP_010220924
MER0482948 Trichechus manatus 1117 245-468 E404 H403, H407, H413 GENBANK:XP_004374604
MER0598957 Tupaia chinensis 961 245-468 E404 H403, H407, H413 GENBANK:XP_006170484
MER0101327 Ursus maritimus 807 48-158 E94 H93, H97, H103 GENBANK:XP_008689891
MER0260023 Vicugna pacos 1117 245-468 E404 H403, H407, H413 GENBANK:XP_006197580
MER0346194 Xenopus tropicalis 1079 243-462 E398 H397, H401, H407 GENBANK:XP_002934253
MER0455371 Xiphophorus maculatus 1121 249-472 E408 H407, H411, H417 GENBANK:XP_005802513
MER0448704 Zonotrichia albicollis 1119 247-470 E406 H405, H409, H415 GENBANK:XP_005493039

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