Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Sequence features for C26.A31: GMP synthase (Pyrococcus furiosus)

Summary Alignment Tree Sequences Sequence features Distribution Structure

 

MERNUM Species Sequence length Peptidase unit Active site residues Source
MER0247086 Acidianus hospitalis 188 1-188 C79, H166, E168 UNIPROT:F4B8L6
MER0247086 Acidianus hospitalis 188 1-188 C79, H166, E168 UNIPROT:F4B8L6
MER0198361 Aciduliprofundum boonei 196 1-196 C87, H174, E176 UNIPROT:D3TCY2
MER0198361 Aciduliprofundum boonei 196 1-196 C87, H174, E176 UNIPROT:D3TCY2
MER0053222 Aeropyrum pernix 512 1-202 C87, H173, E175 UNIPROT:Q9Y933
MER0053222 Aeropyrum pernix 512 1-202 C87, H173, E175 UNIPROT:Q9Y933
MER0053222 Aeropyrum pernix 512 1-202 C87, H173, E175 UNIPROT:Q9Y933
MER0059747 Archaeoglobus fulgidus 183 1-183 C74, H161, E163 UNIPROT:O28949
MER0059747 Archaeoglobus fulgidus 183 1-183 C74, H161, E163 UNIPROT:O28949
MER0196754 Archaeoglobus profundus 184 1-184 C75, H162, E164 UNIPROT:D2RI69
MER0196754 Archaeoglobus profundus 184 1-184 C75, H162, E164 UNIPROT:D2RI69
MER0498111 Archaeoglobus sulfaticallidus 183 3-178 C74, H161, E163 UNIPROT:N0BKX7
MER0498111 Archaeoglobus sulfaticallidus 183 3-178 C74, H161, E163 UNIPROT:N0BKX7
MER0242662 Archaeoglobus veneficus 184 1-184 C75, H162, E164 UNIPROT:F2KSS2
MER0242662 Archaeoglobus veneficus 184 1-184 C75, H162, E164 UNIPROT:F2KSS2
MER0099910 Caldivirga maquilingensis 188 1-188 C81, H167, E169 UNIPROT:A8ME24
MER0099910 Caldivirga maquilingensis 188 1-188 C81, H167, E169 UNIPROT:A8ME24
MER0503430 Candidatus Methanomethylophilus alvus 191 2-188 C79, H166, E168 UNIPROT:M9S8T2
MER0503430 Candidatus Methanomethylophilus alvus 191 2-188 C79, H166, E168 UNIPROT:M9S8T2
MER0281220 Candidatus Methanoregula boonei 184 1-184 C75, H162, E164 UNIPROT:A7I661
MER0281220 Candidatus Methanoregula boonei 184 1-184 C75, H162, E164 UNIPROT:A7I661
MER0198080 Ferroglobus placidus 183 1-183 C74, H161, E163 UNIPROT:D3RWW1
MER0198080 Ferroglobus placidus 183 1-183 C74, H161, E163 UNIPROT:D3RWW1
MER0443418 Haladaptatus paucihalophilus 182 4-181 C73, H161, E163 GENBANK:ZP_08044705
MER0220069 Halalkalicoccus jeotgali 181 1-181 C72, H160, E162 UNIPROT:D8J6Z6
MER0220069 Halalkalicoccus jeotgali 181 1-181 C72, H160, E162 UNIPROT:D8J6Z6
MER0272564 Haloarcula hispanica 189 1-189 C73, H161, E163 UNIPROT:G0HWK4
MER0272564 Haloarcula hispanica 189 1-189 C73, H161, E163 UNIPROT:G0HWK4
MER0043357 Halobacterium salinarum 183 1-183 C74, H162, E164 UNIPROT:Q9HSH4
MER0043357 Halobacterium salinarum 183 1-183 C74, H162, E164 UNIPROT:Q9HSH4
MER0043357 Halobacterium salinarum 183 1-183 C74, H162, E164 UNIPROT:Q9HSH4
MER0443338 Halobacterium sp. DL1 183 4-182 C74, H162, E164 GENBANK:ZP_09030058
MER0442927 Halobiforma lacisalsi 184 4-181 C73, H161, E163 GENBANK:ZP_09948484
MER0202296 Haloferax volcanii 183 1-183 C73, H161, E163 UNIPROT:D4GSQ7
MER0202296 Haloferax volcanii 183 1-183 C73, H161, E163 UNIPROT:D4GSQ7
MER0272873 halophilic archaeon DL31 184 1-184 C73, H161, E163 UNIPROT:G2MMS8
MER0272873 halophilic archaeon DL31 184 1-184 C73, H161, E163 UNIPROT:G2MMS8
MER0252119 Halopiger xanaduensis 184 1-184 C73, H161, E163 UNIPROT:F8D494
MER0252119 Halopiger xanaduensis 184 1-184 C73, H161, E163 UNIPROT:F8D494
MER0068734 Haloquadratum walsbyi 184 1-184 C75, H163, E165 UNIPROT:Q18KM8
MER0068734 Haloquadratum walsbyi 184 1-184 C75, H163, E165 UNIPROT:Q18KM8
MER0443368 Halorhabdus tiamatea 182 4-181 C73, H161, E163 GENBANK:ZP_08559832
MER0155277 Halorubrum lacusprofundi 184 1-184 C73, H161, E163 UNIPROT:B9LTN9
MER0155277 Halorubrum lacusprofundi 184 1-184 C73, H161, E163 UNIPROT:B9LTN9
MER0196644 Haloterrigena turkmenica 184 1-184 C73, H161, E163 UNIPROT:D2RQP4
MER0196644 Haloterrigena turkmenica 184 1-184 C73, H161, E163 UNIPROT:D2RQP4
MER0066169 Ignicoccus hospitalis 188 1-188 C79, H166, E168 UNIPROT:A8AC69
MER0066169 Ignicoccus hospitalis 188 1-188 C79, H166, E168 UNIPROT:A8AC69
MER0066169 Ignicoccus hospitalis 188 1-188 C79, H166, E168 UNIPROT:A8AC69
MER0244574 Metallosphaera cuprina 188 1-188 C79, H166, E168 UNIPROT:F4G2C6
MER0244574 Metallosphaera cuprina 188 1-188 C79, H166, E168 UNIPROT:F4G2C6
MER0060382 Metallosphaera sedula 189 1-189 C79, H166, E168 UNIPROT:A4YGH0
MER0060382 Metallosphaera sedula 189 1-189 C79, H166, E168 UNIPROT:A4YGH0
MER0441897 Metallosphaera yellowstonensis 188 9-186 C79, H166, E168 GENBANK:ZP_09705697
MER0240871 Methanobacterium sp. AL-21 190 1-190 C76, H163, E165 UNIPROT:F0T661
MER0240871 Methanobacterium sp. AL-21 190 1-190 C76, H163, E165 UNIPROT:F0T661
MER0248837 Methanobacterium sp. SWAN-1 188 1-188 C76, H163, E165 UNIPROT:F6D2J2
MER0248837 Methanobacterium sp. SWAN-1 188 1-188 C76, H163, E165 UNIPROT:F6D2J2
MER0197477 Methanobrevibacter ruminantium 188 1-188 C76, H163, E165 UNIPROT:D3E411
MER0197477 Methanobrevibacter ruminantium 188 1-188 C76, H163, E165 UNIPROT:D3E411
MER0438237 Methanobrevibacter smithii 190 3-183 C76, H163, E165 UNIPROT:D2ZS92
MER0438237 Methanobrevibacter smithii 190 3-183 C76, H163, E165 UNIPROT:D2ZS92
MER0504773 Methanobrevibacter sp. AbM4 187 2-179 C76, H163, E165, UNIPROT:R9SL79
MER0504773 Methanobrevibacter sp. AbM4 187 2-179 C76, H163, E165, UNIPROT:R9SL79
MER0439014 Methanocaldococcus fervens 189 1-184 C76, H163, E165 UNIPROT:C7P5E7
MER0439014 Methanocaldococcus fervens 189 1-184 C76, H163, E165 UNIPROT:C7P5E7
MER0439385 Methanocaldococcus infernus 184 1-182 C73, H160, E162 UNIPROT:D5VTB0
MER0439385 Methanocaldococcus infernus 184 1-182 C73, H160, E162 UNIPROT:D5VTB0
MER0045294 Methanocaldococcus jannaschii 188 1-188 C76, H163, E165 UNIPROT:Q58970
MER0045294 Methanocaldococcus jannaschii 188 1-188 C76, H163, E165 UNIPROT:Q58970
MER0045294 Methanocaldococcus jannaschii 188 1-188 C76, H163, E165 UNIPROT:Q58970
MER0198601 Methanocaldococcus sp. FS406-22 188 1-188 C76, H163, E165 UNIPROT:D3S770
MER0198601 Methanocaldococcus sp. FS406-22 188 1-188 C76, H163, E165 UNIPROT:D3S770
MER0194855 Methanocaldococcus vulcanius 187 1-187 C76, H163, E165 UNIPROT:C9REW9
MER0194855 Methanocaldococcus vulcanius 187 1-187 C76, H163, E165 UNIPROT:C9REW9
MER0231454 Methanocella arvoryzae 189 1-189 C78, H165, E167 UNIPROT:Q0W700
MER0231454 Methanocella arvoryzae 189 1-189 C78, H165, E167 UNIPROT:Q0W700
MER0148507 Methanocella conradii 188 16-188 C78, H165, E167 UNIPROT:H8I998
MER0148507 Methanocella conradii 188 16-188 C78, H165, E167 UNIPROT:H8I998
MER0441525 Methanocella paludicola 188 6-185 C78, H165, E167 UNIPROT:D1Z2J6
MER0441525 Methanocella paludicola 188 6-185 C78, H165, E167 UNIPROT:D1Z2J6
MER0440538 Methanococcoides burtonii 189 6-186 C79, H166, E168 UNIPROT:Q12UJ5
MER0440538 Methanococcoides burtonii 189 6-186 C79, H166, E168 UNIPROT:Q12UJ5
MER0059831 Methanococcus vannielii 189 1-189 C76, H163, E165 UNIPROT:A6UQ90
MER0059831 Methanococcus vannielii 189 1-189 C76, H163, E165 UNIPROT:A6UQ90
MER0212120 Methanococcus voltae 188 1-188 C76, H163, E165 UNIPROT:D7DQK5
MER0212120 Methanococcus voltae 188 1-188 C76, H163, E165 UNIPROT:D7DQK5
MER0441668 Methanohalobium evestigatum 189 6-186 C79, H166, E168 UNIPROT:D7EB13
MER0441668 Methanohalobium evestigatum 189 6-186 C79, H166, E168 UNIPROT:D7EB13
MER0203499 Methanohalophilus mahii 191 1-191 C79, H166, E168 UNIPROT:D5E9C4
MER0203499 Methanohalophilus mahii 191 1-191 C79, H166, E168 UNIPROT:D5E9C4
MER0444618 Methanolinea tarda 187 4-184 C75, H162, E164 GENBANK:ZP_09042516
MER0443969 Methanoplanus limicola 186 4-184 C75, H162, E164 GENBANK:ZP_09701054
MER0223452 Methanoplanus petrolearius 186 1-186 C75, H162, E164 UNIPROT:E1RIE4
MER0223452 Methanoplanus petrolearius 186 1-186 C75, H162, E164 UNIPROT:E1RIE4
MER0043560 Methanopyrus kandleri 187 1-187 C76, H164, E166 UNIPROT:Q8TXV8
MER0043560 Methanopyrus kandleri 187 1-187 C76, H164, E166 UNIPROT:Q8TXV8
MER0043560 Methanopyrus kandleri 187 1-187 C76, H164, E166 UNIPROT:Q8TXV8
MER0243703 Methanosaeta concilii 188 1-188 C79, H166, E168 UNIPROT:F4BZ84
MER0243703 Methanosaeta concilii 188 1-188 C79, H166, E168 UNIPROT:F4BZ84
MER0123240 Methanosaeta harundinacea 181 13-181 C72, H159, E161 UNIPROT:G7WM63
MER0123240 Methanosaeta harundinacea 181 13-181 C72, H159, E161 UNIPROT:G7WM63
MER0071337 Methanosaeta thermophila 181 1-181 C72, H159, E161 UNIPROT:A0B5J1
MER0071337 Methanosaeta thermophila 181 1-181 C72, H159, E161 UNIPROT:A0B5J1
MER0071337 Methanosaeta thermophila 181 1-181 C72, H159, E161 UNIPROT:A0B5J1
MER0252392 Methanosalsum zhilinae 189 1-189 C79, H166, E168 UNIPROT:F7XL71
MER0252392 Methanosalsum zhilinae 189 1-189 C79, H166, E168 UNIPROT:F7XL71
MER0043568 Methanosarcina acetivorans 189 1-189 C79, H166, E168 UNIPROT:Q8THC7
MER0043568 Methanosarcina acetivorans 189 1-189 C79, H166, E168 UNIPROT:Q8THC7
MER0043568 Methanosarcina acetivorans 189 1-189 C79, H166, E168 UNIPROT:Q8THC7
MER0068592 Methanosarcina barkeri 189 1-189 C79, H166, E168 UNIPROT:Q46E00
MER0068592 Methanosarcina barkeri 189 1-189 C79, H166, E168 UNIPROT:Q46E00
MER0043583 Methanosarcina mazei 189 1-189 C79, H166, E168 UNIPROT:Q8PXF0
MER0059663 Methanosphaera stadtmanae 186 1-186 C76, H163, E165 UNIPROT:Q2NER5
MER0059663 Methanosphaera stadtmanae 186 1-186 C76, H163, E165 UNIPROT:Q2NER5
MER0152475 Methanosphaerula palustris 185 1-185 C75, H162, E164 UNIPROT:B8GIP7
MER0152475 Methanosphaerula palustris 185 1-185 C75, H162, E164 UNIPROT:B8GIP7
MER0442710 Methanospirillum hungatei 188 4-182 C75, H162, E164 UNIPROT:Q2FL30
MER0442710 Methanospirillum hungatei 188 4-182 C75, H162, E164 UNIPROT:Q2FL30
MER0223045 Methanothermobacter marburgensis 186 1-186 C75, H162, E164 UNIPROT:D9PWU5
MER0223045 Methanothermobacter marburgensis 186 1-186 C75, H162, E164 UNIPROT:D9PWU5
MER0439061 Methanothermococcus okinawensis 189 1-184 C76, H163, E165 UNIPROT:F8ANH8
MER0439061 Methanothermococcus okinawensis 189 1-184 C76, H163, E165 UNIPROT:F8ANH8
MER0227272 Methanothermus fervidus 184 1-184 C75, H162, E164 UNIPROT:E3GYC8
MER0227272 Methanothermus fervidus 184 1-184 C75, H162, E164 UNIPROT:E3GYC8
MER0439119 Methanotorris formicicus 189 1-184 C76, H163, E165 GENBANK:ZP_09708029
MER0248957 Methanotorris igneus 189 1-189 C76, H163, E165 UNIPROT:F6BBT4
MER0248957 Methanotorris igneus 189 1-189 C76, H163, E165 UNIPROT:F6BBT4
MER0198970 Natrialba magadii 184 1-184 C73, H161, E163 UNIPROT:D3SXQ5
MER0198970 Natrialba magadii 184 1-184 C73, H161, E163 UNIPROT:D3SXQ5
MER0058889 Natronomonas pharaonis 184 1-184 C73, H161, E163 UNIPROT:Q3ITY2
MER0058889 Natronomonas pharaonis 184 1-184 C73, H161, E163 UNIPROT:Q3ITY2
MER0058889 Natronomonas pharaonis 184 1-184 C73, H161, E163 UNIPROT:Q3ITY2
MER0056673 Picrophilus torridus 188 1-188 C79, H166, E168 UNIPROT:Q6KZC5
MER0056673 Picrophilus torridus 188 1-188 C79, H166, E168 UNIPROT:Q6KZC5
MER0056673 Picrophilus torridus 188 1-188 C79, H166, E168 UNIPROT:Q6KZC5
MER0093000 Pyrobaculum arsenaticum 505 1-192 C80, H164, E166 UNIPROT:A4WLQ6
MER0093000 Pyrobaculum arsenaticum 505 1-192 C80, H164, E166 UNIPROT:A4WLQ6
MER0143158 Pyrobaculum oguniense 505 1-215 C80, H164, E166 UNIPROT:H6Q7N0
MER0143158 Pyrobaculum oguniense 505 1-215 C80, H164, E166 UNIPROT:H6Q7N0
MER0044382 Pyrococcus abyssi 188 1-188 C78, H165, E167 UNIPROT:Q9V0I6
MER0044382 Pyrococcus abyssi 188 1-188 C78, H165, E167 UNIPROT:Q9V0I6
MER0044382 Pyrococcus abyssi 188 1-188 C78, H165, E167 UNIPROT:Q9V0I6
MER0043537 Pyrococcus furiosus 188 1-188 C78, H165, E167 UNIPROT:Q8U0R9
MER0043537 Pyrococcus furiosus 188 1-188 C78, H165, E167 UNIPROT:Q8U0R9
MER0043537 Pyrococcus furiosus 188 1-188 C78, H165, E167 UNIPROT:Q8U0R9
MER0044755 Pyrococcus horikoshii 189 1-189 C79, H166, E168 UNIPROT:O59071
MER0044755 Pyrococcus horikoshii 189 1-189 C79, H166, E168 UNIPROT:O59071
MER0044755 Pyrococcus horikoshii 189 1-189 C79, H166, E168 UNIPROT:O59071
MER0245413 Pyrococcus sp. NA2 188 1-188 C78, H165, E167 UNIPROT:F4HLN3
MER0245413 Pyrococcus sp. NA2 188 1-188 C78, H165, E167 UNIPROT:F4HLN3
MER0252918 Pyrococcus yayanosii 188 1-188 C78, H165, E167 UNIPROT:F8AES2
MER0252918 Pyrococcus yayanosii 188 1-188 C78, H165, E167 UNIPROT:F8AES2
MER0274340 Pyrolobus fumarii 190 13-190 C81, H168, E170 UNIPROT:G0ECN6
MER0274340 Pyrolobus fumarii 190 13-190 C81, H168, E170 UNIPROT:G0ECN6
MER0441833 Selenomonas artemidis 519 9-234 C87, H175, E177 GENBANK:ZP_08030239
MER0069561 Sulfolobus acidocaldarius 188 1-188 C79, H166, E168 GENBANK:YP_255237
MER0069561 Sulfolobus acidocaldarius 188 1-188 C79, H166, E168 GENBANK:YP_255237
MER0069561 Sulfolobus acidocaldarius 188 1-188 C79, H166, E168 GENBANK:YP_255237
MER0069561 Sulfolobus acidocaldarius 188 1-188 C79, H166, E168 GENBANK:YP_255237
MER0182042 Sulfolobus islandicus 188 1-188 C79, H166, E168 UNIPROT:C4KKS7
MER0182042 Sulfolobus islandicus 188 1-188 C79, H166, E168 UNIPROT:C4KKS7
MER0043458 Sulfolobus solfataricus 188 1-188 C79, H166, E168 UNIPROT:Q97VZ9
MER0043458 Sulfolobus solfataricus 188 1-188 C79, H166, E168 UNIPROT:Q97VZ9
MER0043458 Sulfolobus solfataricus 188 1-188 C79, H166, E168 UNIPROT:Q97VZ9
MER0044785 Sulfolobus tokodaii 188 1-188 C79, H166, E168 GENBANK:BAB65573
MER0044785 Sulfolobus tokodaii 188 1-188 C79, H166, E168 GENBANK:BAB65573
MER0230763 Thermococcus barophilus 188 1-188 C78, H165, E167 UNIPROT:F0LLH5
MER0230763 Thermococcus barophilus 188 1-188 C78, H165, E167 UNIPROT:F0LLH5
MER0182391 Thermococcus gammatolerans 188 1-188 C78, H165, E167 UNIPROT:C5A4V3
MER0182391 Thermococcus gammatolerans 188 1-188 C78, H165, E167 UNIPROT:C5A4V3
MER0438963 Thermococcus litoralis 188 1-188 C78, H165, E167 GENBANK:ZP_09729634
MER0145073 Thermococcus onnurineus 188 1-188 C78, H165, E167 UNIPROT:B6YVR1
MER0145073 Thermococcus onnurineus 188 1-188 C78, H165, E167 UNIPROT:B6YVR1
MER0182472 Thermococcus sibiricus 188 1-188 C78, H165, E167 UNIPROT:C6A0H0
MER0182472 Thermococcus sibiricus 188 1-188 C78, H165, E167 UNIPROT:C6A0H0
MER0255687 Thermococcus sp. 4557 189 1-189 C78, H165, E167 UNIPROT:G0HJB5
MER0255687 Thermococcus sp. 4557 189 1-189 C78, H165, E167 UNIPROT:G0HJB5
MER0439038 Thermococcus sp. AM4 188 1-188 C78, H165, E167 UNIPROT:B7R039
MER0439038 Thermococcus sp. AM4 188 1-188 C78, H165, E167 UNIPROT:B7R039
MER0498787 Thermofilum sp. 1910b 523 7-204 C90, H177, E179 GENBANK:YP_008432393
MER0044643 Thermoplasma acidophilum 200 1-200 C80, H167, E169 UNIPROT:Q9HJM3
MER0044643 Thermoplasma acidophilum 200 1-200 C80, H167, E169 UNIPROT:Q9HJM3
MER0044643 Thermoplasma acidophilum 200 1-200 C80, H167, E169 UNIPROT:Q9HJM3
MER0044783 Thermoplasma volcanium 202 1-202 C81, H168, E170 UNIPROT:Q979P8
MER0044783 Thermoplasma volcanium 202 1-202 C81, H168, E170 UNIPROT:Q979P8
MER0044783 Thermoplasma volcanium 202 1-202 C81, H168, E170 UNIPROT:Q979P8
MER0443540 Thermosphaera aggregans 521 2-238 C91, H179, E181 UNIPROT:D5U1Q3
MER0443540 Thermosphaera aggregans 521 2-238 C91, H179, E181 UNIPROT:D5U1Q3
MER0442493 uncultured marine group II euryarchaeote 174 2-167 C59, H147, E149 GENBANK:EHR75711
MER0442733 Vulcanisaeta distributa 189 5-186 C80, H166, E168 UNIPROT:E1QV85
MER0442733 Vulcanisaeta distributa 189 5-186 C80, H166, E168 UNIPROT:E1QV85
MER0442817 Vulcanisaeta moutnovskia 187 5-186 C80, H166, E168 UNIPROT:F0QT54
MER0442817 Vulcanisaeta moutnovskia 187 5-186 C80, H166, E168 UNIPROT:F0QT54

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use