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Literature for peptidase T02.004: taspase-1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, V Review, M Mutation, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Hommel,K., Kauth,A.A., Kirupakaran,A., Theisen,S., Hayduk,M., Niemeyer,F.C., Beuck,C., Zadmard,R., Bayer,P., Ravoo,B.J., Voskuhl,J., Schrader,T. and Knauer,S.K.
    Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1
    Chemistrye202401542-e202401542. PubMed  Europe PubMed DOI
    2. 2022
  2. Hensel,A., Stahl,P., Moews,L., Konig,L., Patwardhan,R., Hoing,A., Schulze,N., Nalbant,P., Stauber,R.H. and Knauer,S.K.
    The Taspase1/Myosin1f-axis regulates filopodia dynamics
    iScience25, 104355-104355. PubMed  Europe PubMed DOI
  3. Hoing,A., Kirupakaran,A., Beuck,C., Porschke,M., Niemeyer,F.C., Seiler,T., Hartmann,L., Bayer,P., Schrader,T. and Knauer,S.K.
    Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers
    Biomacromolecules23, 4504-4518. PubMed  Europe PubMed DOI
    4. 2021
  4. Hoing,A., Zimmermann,A., Moews,L., Killa,M., Heimann,M., Hensel,A., Voskuhl,J. and Knauer,S.K.
    A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin alpha Interaction
    ChemMedChem PubMed  Europe PubMed DOI
    5. 2020
  5. van den Boom,J., Hensel,A., Trusch,F., Matena,A., Siemer,S., Guel,D., Docter,D., Hoing,A., Bayer,P., Stauber,R.H. and Knauer,S.K.
    The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent manner
    Nanoscale12, 19093-19103. PubMed  Europe PubMed DOI
  6. Wang,F., Li,P., Shao,Y., Li,Y., Zhang,K., Li,M., Wang,R., Zheng,S., Wang,Y., Song,S., Feng,S., Liu,F., Xiao,W. and Li,X.
    Site-specific proteolytic cleavage prevents ubiquitination and degradation of human REV3L, the catalytic subunit of DNA polymerase zeta
    Nucleic Acids Res48, 3619-3637. PubMed  Europe PubMed DOI
  7. Zhang,Y., Du,P., Li,Y., Zhu,Q., Song,X., Liu,S., Hao,J., Liu,L., Liu,F., Hu,Y., Jiang,L., Ma,Q., Lu,W. and Liu,Y.
    TASP1 Promotes gallbladder cancer cell proliferation and metastasis by up-regulating FAM49B via PI3K/AKT pathway
    Int J Biol Sci16, 739-751. PubMed  Europe PubMed DOI
    8. 2019
  8. Balkin,D.M., Poranki,M., Forester,C.M., Dorsey,M.J., Slavotinek,A. and Pomerantz,J.H.
    TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia
    Mol Genet Genomic Mede818-e818. PubMed  Europe PubMed DOI  M
  9. Suleiman,J., Riedhammer,K.M., Jicinsky,T., Mundt,M., Werner,L., Gusic,M., Burgemeister,A.L., Alsaif,H.S., Abdulrahim,M., Moghrabi,N.N., Nicolas-Jilwan,M., AlSayed,M., Bi,W., Sampath,S., Alkuraya,F.S. and El-Hattab,A.W.
    Homozygous loss-of-function variants of TASP1, a gene encoding an activator of the histone methyltransferases KMT2A and KMT2D, cause a syndrome of developmental delay, happy demeanor, distinctive facial features, and congenital anomalies
    Hum Mutat40, 1985-1992. PubMed  Europe PubMed DOI  M
  10. Zhao,Z., Wang,L., Volk,A.G., Birch,N.W., Stoltz,K.L., Bartom,E.T., Marshall,S.A., Rendleman,E.J., Nestler,C.M., Shilati,J., Schiltz,G.E., Crispino,J.D. and Shilatifard,A.
    Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia
    Genes Dev33, 61-74. PubMed  Europe PubMed DOI  K
    11. 2018
  11. Schrenk,C., Fetz,V., Vallet,C., Heiselmayer,C., Schroder,E., Hensel,A., Hahlbrock,A., Wunsch,D., Goesswein,D., Bier,C., Habtemichael,N., Schneider,G., Stauber,R.H. and Knauer,S.K.
    TFIIA transcriptional activity is controlled by a 'cleave-and-run' exportin-1/taspase 1-switch
    J Mol Cell Biol10, 33-47. PubMed  Europe PubMed DOI
  12. Suleiman,J., Mundt,M., Sampath,S. and El-Hattab,A.W.
    TASP1 is deleted in an infant with developmental delay, microcephaly, distinctive facial features, and multiple congenital anomalies
    Clin Genet94, 170-173. PubMed  Europe PubMed DOI  M
    13. 2017
  13. Gribko,A., Hahlbrock,A., Strieth,S., Becker,S., Hagemann,J., Deichelbohrer,M., Hildebrandt,A., Habtemichael,N. and Wu Nsch,D.
    Disease-relevant signalling-pathways in head and neck cancer: taspase1's proteolytic activity fine-tunes TFIIA function
    Sci Rep7, 14937-14937. PubMed  Europe PubMed DOI
    14. 2016
  14. Hahlbrock,A., Goesswein,D., Kunzel,J., Wunsch,D. and Stauber,R.H.
    Threonine aspartase1: an unexplored protease with relevance for oral oncology?
    Oral Oncol54, e10-e12. PubMed  Europe PubMed DOI  I
  15. Stauber,R.H., Hahlbrock,A., Knauer,S.K. and Wunsch,D.
    Cleaving for growth: threonine aspartase 1-a protease relevant for development and disease
    FASEB J30, 1012-1022. PubMed  Europe PubMed DOI  V
  16. van den Boom,J., Trusch,F., Hoppstock,L., Beuck,C. and Bayer,P.
    Structural characterization of the loop at the alpha-subunit C-terminus of the mixed lineage leukemia protein activating protease taspase1
    PLoS ONE11, e0151431-e0151431. PubMed  Europe PubMed DOI
  17. Wunsch,D., Hahlbrock,A., Jung,S., Schirmeister,T., van den Boom,J., Schilling,O., Knauer,S.K. and Stauber,R.H.
    Taspase1: a 'misunderstood' protease with translational cancer relevance
    Oncogene35, 3351-3364. PubMed  Europe PubMed DOI  V
    18. 2015
  18. Malecova,B., Caputo,V.S., Lee,D.F., Hsieh,J.J. and Oelgeschlager,T.
    Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID
    Transcription6, 21-32. PubMed  Europe PubMed DOI
  19. Niizuma,H., Cheng,E.H. and Hsieh,J.J.
    Taspase 1: a protease with many biological surprises
    Mol Cell Oncol2, e999513-e999513. PubMed  Europe PubMed DOI  T
  20. Wunsch,D., Hahlbrock,A., Heiselmayer,C., Backer,S., Heun,P., Goesswein,D., Stocker,W., Schirmeister,T., Schneider,G., Kramer,O.H., Knauer,S.K. and Stauber,R.H.
    Fly versus man: evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's taspase1
    FASEB J29, 1973-1985. PubMed  Europe PubMed DOI
  21. Wunsch,D., Hahlbrock,A., Heiselmayer,C., Backer,S., Schrenk,C., Benne,F., Schilling,O. and Knauer,S.K.
    Evolutionary divergence of threonine aspartase1 leads to species-specific substrate recognition
    Biol Chem396, 367-376. PubMed  Europe PubMed DOI
    22. 2014
  22. Dong,Y., Van Tine,B.A., Oyama,T., Wang,P.I., Cheng,E.H. and Hsieh,J.J.
    Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis
    Cell Res24, 1354-1366. PubMed  Europe PubMed DOI  K
  23. van den Boom,J., Mamic,M., Baccelliere,D., Zweerink,S., Kaschani,F., Knauer,S., Bayer,P. and Kaiser,M.
    Peptidyl succinimidyl peptides as taspase 1 inhibitors
    Chembiochem15, 2233-2237. PubMed  Europe PubMed DOI  I
    24. 2013
  24. Freiman,R.N.
    Processing the complexities of transcription
    Dev Cell27, 123-124. PubMed  Europe PubMed DOI
  25. Oyama,T., Sasagawa,S., Takeda,S., Hess,R.A., Lieberman,P.M., Cheng,E.H. and Hsieh,J.J.
    Cleavage of TFIIA by taspase1 activates TRF2-specified mammalian male germ cell programs
    Dev Cell27, 188-200. PubMed  Europe PubMed DOI
  26. Stauber,R.H. and Knauer,S.K.
    Protease research: Taspase 1 - license to cut
    BioSpektrum19, 134-136. DOI
    27. 2012
  27. Bier,C., Hecht,R., Kunst,L., Scheiding,S., Wunsch,D., Goesswein,D., Schneider,G., Kramer,O.H., Knauer,S.K. and Stauber,R.H.
    Overexpression of the catalytically impaired taspase1 T234V or taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cells
    PLoS ONE7, e34142-e34142. PubMed  Europe PubMed DOI
  28. Bier,C., Knauer,S.K., Wunsch,D., Kunst,L., Scheiding,S., Kaiser,M., Ottmann,C., Kramer,O.H. and Stauber,R.H.
    Allosteric inhibition of taspase1's pathobiological activity by enforced dimerization in vivo
    FASEB J26, 3421-3429. PubMed  Europe PubMed DOI
  29. Chen,D.Y., Lee,Y., Van Tine,B.A., Searleman,A.C., Westergard,T.D., Liu,H., Tu,H.C., Takeda,S., Dong,Y., Piwnica-Worms,D.R., Oh,K.J., Korsmeyer,S.J., Hermone,A., Gussio,R., Shoemaker,R.H., Cheng,E.H. and Hsieh,J.J.
    A pharmacologic inhibitor of the protease taspase1 effectively inhibits breast and brain tumor growth
    Cancer Res72, 736-746. PubMed  Europe PubMed DOI  K  I
  30. Cunha,L., Tong,L. and Hsieh,J.J.D.
    Taspase 1
    [ISSN:978-0-12-407742-3]3, 3723-3728. DOI
  31. Wunsch,D., Fetz,V., Heider,D., Tenzer,S., Bier,C., Kunst,L., Knauer,S. and Stauber,R.
    Chemico-genetic strategies to inhibit the leukemic potential of threonine aspartase-1
    Blood Cancer J2, e77-e77. PubMed  Europe PubMed DOI  I
    32. 2011
  32. Bier,C., Knauer,S.K., Docter,D., Schneider,G., Kramer,O.H. and Stauber,R.H.
    The importin-alpha/nucleophosmin switch controls taspase1 protease function
    Traffic12, 703-714. PubMed  Europe PubMed DOI
  33. Bier,C., Knauer,S.K., Klapthor,A., Schweitzer,A., Rekik,A., Kramer,O.H., Marschalek,R. and Stauber,R.H.
    Cell-based analysis of structure-function activity of threonine aspartase 1
    J Biol Chem286, 3007-3017. PubMed  Europe PubMed DOI
  34. Knauer,S.K., Fetz,V., Rabenstein,J., Friedl,S., Hofmann,B., Sabiani,S., Schroder,E., Kunst,L., Proschak,E., Thines,E., Kindler,T., Schneider,G., Marschalek,R., Stauber,R.H. and Bier,C.
    Bioassays to monitor taspase1 function for the identification of pharmacogenetic inhibitors
    PLoS ONE6, e18253-e18253. PubMed  Europe PubMed DOI  A
    35. 2010
  35. Chen,D.Y., Liu,H., Takeda,S., Tu,H.C., Sasagawa,S., Van Tine,B.A., Lu,D., Cheng,E.H. and Hsieh,J.J.
    Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis
    Cancer Res70, 5358-5367. PubMed  Europe PubMed DOI
    36. 2009
  36. Lee,J.T., Chen,D.Y., Yang,Z., Ramos,A.D., Hsieh,J.J. and Bogyo,M.
    Design, syntheses, and evaluation of taspase1 inhibitors
    Bioorg Med Chem Lett19, 5086-5090. PubMed  Europe PubMed DOI  I
    37. 2007
  37. Capotosti,F., Hsieh,J.J. and Herr,W.
    Species selectivity of Mixed-Lineage Leukemia/Trithorax and HCF proteolytic maturation pathways
    Mol Cell Biol27, 7063-7072. PubMed  Europe PubMed DOI  P
  38. Hoiby,T., Zhou,H., Mitsiou,D.J. and Stunnenberg,H.G.
    A facelift for the general transcription factor TFIIA
    Biochim Biophys Acta1769, 429-436. PubMed  Europe PubMed DOI
    39. 2006
  39. [YEAR:1-9-2006]Takeda,S., Chen,D.Y., Westergard,T.D., Fisher,J.K., Rubens,J.A., Sasagawa,S., Kan,J.T., Korsmeyer,S.J., Cheng,E.H. and Hsieh,J.J.
    Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression
    Genes Dev20, 2397-2409. PubMed  Europe PubMed DOI  K  T
  40. Zhou,H., Spicuglia,S., Hsieh,J.J., Mitsiou,D.J., Hoiby,T., Veenstra,G.J., Korsmeyer,S.J. and Stunnenberg,H.G.
    Uncleaved TFIIA is a substrate for taspase 1 and active in transcription
    Mol Cell Biol26, 2728-2735. PubMed  Europe PubMed DOI  P
    41. 2005
  41. Khan,J.A., Dunn,B.M. and Tong,L.
    Crystal structure of human taspase1, a crucial protease regulating the function of MLL
    Structure13, 1443-1452. PubMed  Europe PubMed DOI  S
    42. 2003
  42. [YEAR:31-10-2003]Gilliland,D.G.
    Proteolytic processing in development and leukemogenesis
    Cell115, 248-250. PubMed  Europe PubMed
  43. [YEAR:31-10-2003]Hsieh,J.J., Cheng,E.H. and Korsmeyer,S.J.
    Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression
    Cell115, 293-303. PubMed  Europe PubMed DOI
  44. Hsieh,J.J., Ernst,P., Erdjument-Bromage,H., Tempst,P. and Korsmeyer,S.J.
    Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization
    Mol Cell Biol23, 186-194. PubMed  Europe PubMed DOI

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