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Literature for peptidase T01.013: proteasome subunit beta1i

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, A Assay, M Mutation, K Knockout, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Smrdel,L., Stanisic,S., Zajec,Z. and Gobec,M.
    Catalytic proteasome subunits are heterogeneously active in human platelets with beta1i playing a role in signaling and granule release
    Biochim Biophys Acta Mol Cell Res (2025) 1872, 119961-119961. PubMed  Europe PubMed DOI
    2. 2024
  2. Arai,Y., Shitama,H., Yamagishi,M., Ono,S., Kashima,A., Hiraizumi,M., Tsuda,N., Katayama,K., Tanaka,K., Koda,Y., Kato,S., Sakata,K., Nureki,O. and Miyazaki,H.
    Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 (beta5i)/LMP2 (beta1i) dual inhibitor
    Bioorg Med Chem (2024) 109, 117790-117790. PubMed  Europe PubMed DOI  I
  3. Hu,X., Hu,Z., Zhang,H., Zhang,N., Feng,H., Jia,X., Zhang,C. and Cheng,Q.
    Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses
    Cancer Lett (2024) 581, 216466-216466. PubMed  Europe PubMed DOI
    4. 2023
  4. Elhawary,N.A., Ekram,S.N., Abumansour,I.S., Azher,Z.A., AlJahdali,I.A., Alyamani,N.M., Naffadi,H.M., Sindi,I.A., Baazeem,A., Nassir,A.M. and Mufti,A.H.
    Sequence Variants in PSMB8/PSMB9 Immunoproteasome Genes and Risk of Urothelial Bladder Carcinoma
    Cureus (2023) 15, e36293-e36293. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Kim,M., Serwa,R.A., Samluk,L., Suppanz,I., Kodron,A., Stepkowski,T.M., Elancheliyan,P., Tsegaye,B., Oeljeklaus,S., Wasilewski,M., Warscheid,B. and Chacinska,A.
    Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction
    Nat Commun (2023) 14, 4092-4092. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Li,J., Hu,S., Johnson,H.W.B., Kirk,C.J., Xian,P., Song,Y., Li,Y., Liu,N., Groettrup,M. and Basler,M.
    Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis
    Cardiovasc Res (2023) 119, 1030-1045. PubMed  Europe PubMed DOI
    7. 2021
  7. Kanazawa,N., Hemmi,H., Kinjo,N., Ohnishi,H., Hamazaki,J., Mishima,H., Kinoshita,A., Mizushima,T., Hamada,S., Hamada,K., Kawamoto,N., Kadowaki,S., Honda,Y., Izawa,K., Nishikomori,R., Tsumura,M., Yamashita,Y., Tamura,S., Orimo,T., Ozasa,T., Kato,T., Sasaki,I., Fukuda-Ohta,Y., Wakaki-Nishiyama,N., Inaba,Y., Kunimoto,K., Okada,S., Taketani,T., Nakanishi,K., Murata,S., Yoshiura,K.I. and Kaisho,T.
    Heterozygous missense variant of the proteasome subunit beta-type 9 causes neonatal-onset autoinflammation and immunodeficiency
    Nat Commun (2021) 12, 6819-6819. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2020
  8. Bhattarai,D., Lee,M.J., Baek,A., Yeo,I.J., Miller,Z., Baek,Y.M., Lee,S., Kim,D.E., Hong,J.T. and Kim,K.B.
    LMP2 inhibitors as a potential treatment for Alzheimer's disease
    J Med Chem (2020) 63, 3763-3783. PubMed  Europe PubMed DOI  I
  9. Ghannam,K., Martinez Gamboa,L., Kedor,C., Spengler,L., Kuckelkorn,U., Haupl,T., Burmester,G. and Feist,E.
    Response to abatacept is associated with the inhibition of proteasome beta1i expression in T cells of patients with rheumatoid arthritis
    RMD Open (2020) 6 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Karim,M.R., Fisher,C.R., Kapphahn,R.J., Polanco,J.R. and Ferrington,D.A.
    Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
    PLoS ONE (2020) 15, e0231212-e0231212. PubMed  Europe PubMed DOI  PMC  EPMC  K
  11. Li,C., Dai,S., Yan,Z., Zhang,X., Liu,S., Wang,X., Wang,J., Shi,L. and Yao,Y.
    Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population
    Hum Immunol (2020) PubMed  Europe PubMed DOI  M
  12. Maurits,E., Degeling,C.G., Kisselev,A.F., Florea,B.I. and Overkleeft,H.S.
    Structure-Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
    Chembiochem (2020) PubMed  Europe PubMed DOI
  13. Shirazi,F., Jones,R.J., Singh,R.K., Zou,J., Kuiatse,I., Berkova,Z., Wang,H., Lee,H.C., Hong,S., Dick,L., Chattopadhyay,N. and Orlowski,R.Z.
    Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma
    Proc Natl Acad Sci U S A (2020) 117, 20004-20014. PubMed  Europe PubMed DOI
    14. 2019
  14. Allardyce,D.J., Bell,C.M. and Loizidou,E.Z.
    Argyrin B, a non-competitive inhibitor of the human immunoproteasome exhibiting preference for beta1i
    Chem Biol Drug Des (2019) 94, 1556-1567. PubMed  Europe PubMed DOI  I
  15. Ettari,R., Cerchia,C., Maiorana,S., Guccione,M., Novellino,E., Bitto,A., Grasso,S., Lavecchia,A. and Zappala,M.
    Development of novel amides as noncovalent inhibitors of immunoproteasomes
    ChemMedChem (2019) 14, 842-852. PubMed  Europe PubMed DOI  I
  16. Scarpino,A., Bajusz,D., Proj,M., Gobec,M., Sosic,I., Gobec,S., Ferenczy,G.G. and Keseru,G.M.
    Discovery of immunoproteasome inhibitors using large-scale covalent virtual screening
    Molecules (2019) 24 PubMed  Europe PubMed DOI  I
  17. Sun,C., Mo,M., Wang,Y., Yu,W., Song,C., Wang,X., Chen,S. and Liu,Y.
    Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone
    Neurotoxicology (2019) 73, 112-119. PubMed  Europe PubMed DOI
  18. Yeo,I.J., Lee,M.J., Baek,A., Miller,Z., Bhattarai,D., Baek,Y.M., Jeong,H.J., Kim,Y.K., Kim,D.E., Hong,J.T. and Kim,K.B.
    A dual inhibitor of the proteasome catalytic subunits LMP2 and Y attenuates disease progression in mouse models of Alzheimer's disease
    Sci Rep (2019) 9, 18393-18393. PubMed  Europe PubMed DOI  I
    19. 2018
  19. Basler,M., Maurits,E., de Bruin,G., Koerner,J., Overkleeft,H.S. and Groettrup,M.
    Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome
    Br J Pharmacol (2018) 175, 38-52. PubMed  Europe PubMed DOI  I
  20. Basler,M., Lindstrom,M.M., LaStant,J.J., Bradshaw,J.M., Owens,T.D., Schmidt,C., Maurits,E., Tsu,C., Overkleeft,H.S., Kirk,C.J., Langrish,C.L. and Groettrup,M.
    Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity
    EMBO Rep (2018) 19, e46512-e46512. PubMed  Europe PubMed DOI  I
  21. Chen,X., Zhang,X., Chen,T., Jiang,X., Wang,X., Lei,H. and Wang,Y.
    Inhibition of immunoproteasome promotes angiogenesis via enhancing hypoxia-inducible factor-1alpha abundance in rats following focal cerebral ischaemia
    Brain Behav Immun (2018) 73, 167-179. PubMed  Europe PubMed DOI  I
  22. Zanker,D., Pang,K., Oveissi,S., Lu,C., Faou,P., Nowell,C., Mbogo,G.W., Carotta,S., Quillici,C., Karupiah,G., Hibbs,M.L., Nutt,S.L., Neeson,P., Puthalakath,H. and Chen,W.
    LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins
    Immunol Cell Biol (2018) 96, 981-993. PubMed  Europe PubMed DOI  K
    23. 2017
  23. Hewings,D.S., Flygare,J.A., Wertz,I.E. and Bogyo,M.
    Activity-based probes for the multicatalytic proteasome
    FEBS J (2017) 284, 1540-1554. PubMed  Europe PubMed DOI  V  L  I
  24. Hovhannisyan,A.A., Pham,T.H., Bouvier,D., Tan,X., Touhar,S., Mkryan,G.G., Dallakyan,A.M., El Amri,C., Melikyan,G.S., Reboud-Ravaux,M. and Bouvier-Durand,M.
    Phenoxypropanolamine derivatives as selective inhibitors of the 20S proteasome beta1 and beta5 subunits
    Bioorg Med Chem Lett (2017) 27, 5172-5178. PubMed  Europe PubMed DOI  I
  25. Johnson,H.W.B., Anderl,J.L., Bradley,E.K., Bui,J., Jones,J., Arastu-Kapur,S., Kelly,L.M., Lowe,E., Moebius,D.C., Muchamuel,T., Kirk,C., Wang,Z. and McMinn,D.
    Discovery of highly selective inhibitors of the immunoproteasome low molecular mass polypeptide 2 (LMP2) subunit
    ACS Med Chem Lett (2017) 8, 413-417. PubMed  Europe PubMed DOI  PMC  EPMC  I
    26. 2016
  26. de Bruin,G., Xin,B.T., Kraus,M., van der Stelt,M., van der Marel,G.A., Kisselev,A.F., Driessen,C., Florea,B.I. and Overkleeft,H.S.
    A set of activity-based probes to visualize human (immuno)proteasome activities
    Angew Chem Int Ed Engl (2016) 55, 4199-4203. PubMed  Europe PubMed DOI  A  I
  27. Gvozdeva,O.V., Prassolov,V.S., Zenkova,M.A., Vlassov,V.V. and Chernolovskaya,E.L.
    Silencing of inducible immunoproteasome subunit expression by chemically modified siRNA and shRNA
    Nucleosides Nucleotides Nucleic Acids (2016) 35, 389-403. PubMed  Europe PubMed DOI  K
  28. Kuzina,E.S., Kudriaeva,A.A., Maltseva,D.V. and Belogurov AA Jr
    Peptidyl aldehyde specifically interacts with immunosubunit beta1i proteasome: in vitro and in vivo effects
    Bull Exp Biol Med (2016) 161, 69-71. PubMed  Europe PubMed DOI  I
    29. 2015
  29. Beilstein,F., Obiang,L., Raux,H. and Gaudin,Y.
    Characterization of the interaction between the matrix protein of vesicular stomatitis virus and the immunoproteasome subunit LMP2
    J Virol (2015) 89, 11019-11029. PubMed  Europe PubMed DOI
  30. Brehm,A., Liu,Y., Sheikh,A., Marrero,B., Omoyinmi,E., Zhou,Q., Montealegre,G., Biancotto,A., Reinhardt,A., Almeida de Jesus,A., Pelletier,M., Tsai,W.L., Remmers,E.F., Kardava,L., Hill,S., Kim,H., Lachmann,H.J., Megarbane,A., Chae,J.J., Brady,J., Castillo,R.D., Brown,D., Casano,A.V., Gao,L., Chapelle,D., Huang,Y., Stone,D., Chen,Y., Sotzny,F., Lee,C.C., Kastner,D.L., Torrelo,A., Zlotogorski,A., Moir,S., Gadina,M., McCoy,P., Wesley,R., Rother,K., Hildebrand,P.W., Brogan,P., Kruger,E., Aksentijevich,I. and Goldbach-Mansky,R.
    Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production
    J Clin Invest (2015) 125, 4196-4211. PubMed  Europe PubMed DOI  M
    31. 2014
  31. de Bruin,G., Huber,E.M., Xin,B.T., van Rooden,E.J., Al-Ayed,K., Kim,K.B., Kisselev,A.F., Driessen,C., van der Stelt,M., van der Marel,G.A., Groll,M. and Overkleeft,H.S.
    Structure-based design of beta1i or beta5i specific inhibitors of human immunoproteasomes
    J Med Chem (2014) 57, 6197-6209. PubMed  Europe PubMed DOI  S  I
  32. Hovhannisyan,A., Pham,T.H., Bouvier,D., Piroyan,A., Dufau,L., Qin,L., Cheng,Y., Melikyan,G., Reboud-Ravaux,M. and Bouvier-Durand,M.
    New C(4)- and C(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
    Bioorg Med Chem Lett (2014) 24, 1571-1580. PubMed  Europe PubMed DOI  I
    33. 2013
  33. Dechavanne,V., Vilbois,F., Glez,L. and Antonsson,B.
    Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC-MS
    Protein Expr Purif (2013) 87, 100-110. PubMed  Europe PubMed DOI
  34. Miller,Z., Ao,L., Kim,K.B. and Lee,W.
    Inhibitors of the immunoproteasome: current status and future directions
    Curr Pharm Des (2013) 19, 4140-4151. PubMed  Europe PubMed  I
  35. Park,J.E., Ao,L., Miller,Z., Kim,K., Wu,Y., Jang,E.R., Lee,E.Y., Kim,K.B. and Lee,W.
    PSMB9 codon 60 polymorphisms have no impact on the activity of the immunoproteasome catalytic subunit B1i expressed in multiple types of solid cancer
    PLoS ONE (2013) 8, e73732-e73732. PubMed  Europe PubMed DOI  PMC  EPMC
  36. Tacchi,L., Misra,M. and Salinas,I.
    Anti-viral immune responses in a primitive lung: Characterization and expression analysis of interferon-inducible immunoproteasome subunits LMP2, LMP7 and MECL-1 in a sarcopterygian fish, the Nigerian spotted lungfish (Protopterus dolloi)
    Dev Comp Immunol (2013) 41, 657-665. PubMed  Europe PubMed DOI
    37. 2012
  37. Basler,M., Lauer,C., Moebius,J., Weber,R., Przybylski,M., Kisselev,A.F., Tsu,C. and Groettrup,M.
    Why the structure but not the activity of the immunoproteasome subunit low molecular mass polypeptide 2 rescues antigen presentation
    J Immunol (2012) 189, 1868-1877. PubMed  Europe PubMed DOI
  38. Basler,M. and Groettrup,M.
    Immunoproteasome-specific inhibitors and their application
    Methods Mol Biol (2012) 832, 391-401. PubMed  Europe PubMed DOI  I
  39. Grawert,M.A. and Groll,M.
    Eukaryotic 20S proteasome
    [ISSN:978-0-12-407742-3] (2012) 3, 3684-3691. DOI
  40. Haroon,N., Maksymowych,W.P., Rahman,P., Tsui,F.W., O'Shea,F.D. and Inman,R.D.
    Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the Spondyloarthritis Research Consortium of Canada cohort
    Arthritis Rheum (2012) 64, 1119-1126. PubMed  Europe PubMed DOI  M
  41. Wehenkel,M., Ban,J.O., Ho,Y.K., Carmony,K.C., Hong,J.T. and Kim,K.B.
    A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice
    Br J Cancer (2012) 107, 53-62. PubMed  Europe PubMed DOI  I
    42. 2011
  42. Hayashi,T., Horiuchi,A., Sano,K., Hiraoka,N., Kasai,M., Ichimura,T., Nagase,S., Ishiko,O., Shiozawa,T., Kanai,Y., Yaegashi,N., Aburatani,H., Tonegawa,S. and Konishi,I.
    Involvement of proteasome beta1i subunit, LMP2, on development of uterin leiomyosarcma
    North Am J Med Sci (2011) 3, 394-399. PubMed  Europe PubMed DOI
  43. Kuhn,D.J., Orlowski,R.Z. and Bjorklund,C.C.
    Second generation proteasome inhibitors: carfilzomib and immunoproteasome-specific inhibitors (IPSIs)
    Curr Cancer Drug Targets (2011) 11, 285-295. PubMed  Europe PubMed DOI  I
  44. Lee,W. and Kim,K.B.
    The immunoproteasome: an emerging therapeutic target
    Curr Top Med Chem (2011) 11, 2923-2930. PubMed  Europe PubMed
  45. Sijts,E.J. and Kloetzel,P.M.
    The role of the proteasome in the generation of MHC class I ligands and immune responses
    Cell Mol Life Sci (2011) 68, 1491-1502. PubMed  Europe PubMed DOI  V
    46. 2010
  46. Hayashi,T., Horiuchi,A., Sano,K., Hiraoka,N., Kanai,Y., Shiozawa,T., Tonegawa,S. and Konishi,I.
    Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma
    Protein Cell (2010) 1, 711-717. PubMed  Europe PubMed DOI  K
  47. Lei,B., Abdul Hameed,M.D.M., Hamza,A., Wehenkel,M., Muzyka,J.L., Yao,X.J., Kim,K.B. and Zhan,C.G.
    Molecular basis of the selectivity of the immunoproteasome catalytic subunit LMP2-specific inhibitor revealed by molecular modeling and dynamics simulations
    J Phys Chem B (2010) 114, 12333-12339. PubMed  Europe PubMed DOI  I
    48. 2009
  48. Kuhn,D.J., Hunsucker,S.A., Chen,Q., Voorhees,P.M., Orlowski,M. and Orlowski,R.Z.
    Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors
    Blood (2009) 113, 4667-4676. PubMed  Europe PubMed DOI  I
    49. 2007
  49. Ho,Y.K., Bargagna-Mohan,P., Wehenkel,M., Mohan,R. and Kim,K.B.
    LMP2-Specific inhibitors: chemical genetic tools for proteasome biology
    Chem Biol (2007) 14, 419-430. PubMed  Europe PubMed DOI  I
    50. 2006
  50. [YEAR:1-6-2006]Areste,C. and Blackbourn,D.J.
    HIV Tat-mediated transcriptional regulation of proteasome protein cleavage specificity
    Biochem J (1-6-2006) 396, e13-e15. PubMed  Europe PubMed DOI  PMC  EPMC
  51. Ding,Q., Martin,S., Dimayuga,E., Bruce-Keller,A.J. and Keller,J.N.
    LMP2 knock-out mice have reduced proteasome activities and increased levels of oxidatively damaged proteins
    Antioxid Redox Signal (2006) 8, 130-135. PubMed  Europe PubMed DOI  K
    52. 2004
  52. [YEAR:15-9-2004]Basler,M., Youhnovski,N., Van Den Broek,M., Przybylski,M. and Groettrup,M.
    Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus
    J Immunol (15-9-2004) 173, 3925-3934. PubMed  Europe PubMed
  53. Seemuller,E., Dolenc,I. and Lupas,A.
    Eukaryotic 20S proteasome
    [ISSN:0-12-079610-4] (2004) 2, 2068-2077.  V
    54. 2003
  54. Kesmir,C., van Noort,V., de Boer,R.J. and Hogeweg,P.
    Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome
    Immunogenetics (2003) 55, 437-449. PubMed  Europe PubMed DOI
  55. Kruger,E., Kuckelkorn,U., Sijts,A. and Kloetzel,P.M.
    The components of the proteasome system and their role in MHC class I antigen processing
    Rev Physiol Biochem Pharmacol (2003) 148, 81-104. PubMed  Europe PubMed DOI
    56. 2002
  56. [YEAR:15-9-2002]Singh,S., Awasthi,N., Egwuagu,C.E. and Wagner,B.J.
    Immunoproteasome expression in a nonimmune tissue, the ocular lens
    Arch Biochem Biophys (15-9-2002) 405, 147-153. PubMed  Europe PubMed DOI
  57. Unno,M., Mizushima,T., Morimoto,Y., Tomisugi,Y., Tanaka,K., Yasuoka,N. and Tsukihara,T.
    The structure of the mammalian 20S proteasome at 2.75 A resolution
    Structure (2002) 10, 609-618. PubMed  Europe PubMed DOI  S
    58. 2001
  58. [YEAR:2-7-2001]Toes,R.E., Nussbaum,A.K., Degermann,S., Schirle,M., Emmerich,N.P., Kraft,M., Laplace,C., Zwinderman,A., Dick,T.P., Muller,J., Schonfisch,B., Schmid,C., Fehling,H.J., Stevanovic,S., Rammensee,H.G. and Schild,H.
    Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
    J Exp Med (2-7-2001) 194, 1-12. PubMed  Europe PubMed DOI  PMC  EPMC
    59. 2000
  59. [YEAR:15-10-2000]Clark,M.S., Pontarotti,P., Gilles,A., Kelly,A. and Elgar,G.
    Identification and characterization of a beta proteasome subunit cluster in the Japanese pufferfish (Fugu rubripes)
    J Immunol (15-10-2000) 165, 4446-4452. PubMed  Europe PubMed
  60. [YEAR:4-8-2000]Kingsbury,D.J., Griffin,T.A. and Colbert,R.A.
    Novel propeptide function in 20 S proteasome assembly influences beta subunit composition
    J Biol Chem (4-8-2000) 275, 24156-24162. PubMed  Europe PubMed DOI
  61. [YEAR:19-5-2000]Kisselev,A.F., Songyang,Z. and Goldberg,A.L.
    Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
    J Biol Chem (19-5-2000) 275, 14831-14837. PubMed  Europe PubMed DOI  I
  62. [YEAR:15-7-2000]Schwarz,K., Van Den Broek,M., Kostka,S., Kraft,R., Soza,A., Schmidtke,G., Kloetzel,P.M. and Groettrup,M.
    Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope
    J Immunol (15-7-2000) 165, 768-778. PubMed  Europe PubMed
    63. 1998
  63. [YEAR:5-1-1998]Griffin,T.A., Nandi,D., Cruz,M., Fehling,H.J., Van Kaer,L., Monaco,J.J. and Colbert,R.A.
    Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits
    J Exp Med (5-1-1998) 187, 97-104. PubMed  Europe PubMed DOI  PMC  EPMC
    64. 1997
  64. Eleuteri,A.M., Kohanski,R.A., Cardozo,C. and Orlowski,M.
    Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity
    J Biol Chem (1997) 272, 11824-11831. PubMed  Europe PubMed DOI
  65. Hughes,A.L.
    Evolution of the proteasome components
    Immunogenetics (1997) 46, 82-92. PubMed  Europe PubMed DOI
  66. Nonaka,M., Namikawa-Yamada,C., Sasaki,M., Salter-Cid,L. and Flajnik,M.F.
    Evolution of proteasome subunits delta and LMP2: complementary DNA cloning and linkage analysis with MHC in lower vertebrates
    J Immunol (1997) 159, 734-740. PubMed  Europe PubMed
    67. 1996
  67. Coux,O., Tanaka,K. and Goldberg,A.L.
    Structure and functions of the 20S and 26S proteasomes
    Annu Rev Biochem (1996) 65, 801-847. PubMed  Europe PubMed DOI
    68. 1995
  68. [YEAR:6-10-1995]Groettrup,M., Ruppert,T., Kuehn,L., Seeger,M., Standera,S., Koszinowski,U. and Kloetzel,P.M.
    The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro
    J Biol Chem (6-10-1995) 270, 23808-23815. PubMed  Europe PubMed DOI
  69. Sibille,C., Gould,K.G., Willard-Gallo,K., Thomson,S., Rivett,A.J., Powis,S., Butcher,G.W. and De Baetselier,P.
    LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes
    Curr Biol (1995) 5, 923-930. PubMed  Europe PubMed  K
  70. Woodward,E.C. and Monaco,J.J.
    Characterization and mapping of the gene encoding mouse proteasome subunit DELTA (Lmp19)
    Immunogenetics (1995) 42, 28-34. PubMed  Europe PubMed DOI

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