Literature for peptidase T01.013: proteasome subunit beta1i
(Topics flags: S Structure, A Assay, M Mutation, K Knockout, I Inhibitor, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)
-
Arai,Y., Shitama,H., Yamagishi,M., Ono,S., Kashima,A., Hiraizumi,M., Tsuda,N., Katayama,K., Tanaka,K., Koda,Y., Kato,S., Sakata,K., Nureki,O. and Miyazaki,H.
Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 (beta5i)/LMP2 (beta1i) dual inhibitor
Bioorg Med Chem109, 117790-117790. PubMed Europe PubMed DOI I -
Hu,X., Hu,Z., Zhang,H., Zhang,N., Feng,H., Jia,X., Zhang,C. and Cheng,Q.
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses
Cancer Lett581, 216466-216466. PubMed Europe PubMed DOI -
Elhawary,N.A., Ekram,S.N., Abumansour,I.S., Azher,Z.A., AlJahdali,I.A., Alyamani,N.M., Naffadi,H.M., Sindi,I.A., Baazeem,A., Nassir,A.M. and Mufti,A.H.
Sequence Variants in PSMB8/PSMB9 Immunoproteasome Genes and Risk of Urothelial Bladder Carcinoma
Cureus15, e36293-e36293. PubMed Europe PubMed DOI -
Li,J., Hu,S., Johnson,H.W.B., Kirk,C.J., Xian,P., Song,Y., Li,Y., Liu,N., Groettrup,M. and Basler,M.
Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis
Cardiovasc Res119, 1030-1045. PubMed Europe PubMed DOI -
Kanazawa,N., Hemmi,H., Kinjo,N., Ohnishi,H., Hamazaki,J., Mishima,H., Kinoshita,A., Mizushima,T., Hamada,S., Hamada,K., Kawamoto,N., Kadowaki,S., Honda,Y., Izawa,K., Nishikomori,R., Tsumura,M., Yamashita,Y., Tamura,S., Orimo,T., Ozasa,T., Kato,T., Sasaki,I., Fukuda-Ohta,Y., Wakaki-Nishiyama,N., Inaba,Y., Kunimoto,K., Okada,S., Taketani,T., Nakanishi,K., Murata,S., Yoshiura,K.I. and Kaisho,T.
Heterozygous missense variant of the proteasome subunit beta-type 9 causes neonatal-onset autoinflammation and immunodeficiency
Nat Commun12, 6819-6819. PubMed Europe PubMed DOI -
Bhattarai,D., Lee,M.J., Baek,A., Yeo,I.J., Miller,Z., Baek,Y.M., Lee,S., Kim,D.E., Hong,J.T. and Kim,K.B.
LMP2 inhibitors as a potential treatment for Alzheimer's disease
J Med Chem63, 3763-3783. PubMed Europe PubMed DOI I -
Ghannam,K., Martinez Gamboa,L., Kedor,C., Spengler,L., Kuckelkorn,U., Haupl,T., Burmester,G. and Feist,E.
Response to abatacept is associated with the inhibition of proteasome beta1i expression in T cells of patients with rheumatoid arthritis
RMD Open6, PubMed Europe PubMed DOI -
Karim,M.R., Fisher,C.R., Kapphahn,R.J., Polanco,J.R. and Ferrington,D.A.
Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
PLoS ONE15, e0231212-e0231212. PubMed Europe PubMed DOI K -
Li,C., Dai,S., Yan,Z., Zhang,X., Liu,S., Wang,X., Wang,J., Shi,L. and Yao,Y.
Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population
Hum Immunol PubMed Europe PubMed DOI M -
Maurits,E., Degeling,C.G., Kisselev,A.F., Florea,B.I. and Overkleeft,H.S.
Structure-Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
Chembiochem PubMed Europe PubMed DOI -
Shirazi,F., Jones,R.J., Singh,R.K., Zou,J., Kuiatse,I., Berkova,Z., Wang,H., Lee,H.C., Hong,S., Dick,L., Chattopadhyay,N. and Orlowski,R.Z.
Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma
Proc Natl Acad Sci U S A117, 20004-20014. PubMed Europe PubMed DOI -
Allardyce,D.J., Bell,C.M. and Loizidou,E.Z.
Argyrin B, a non-competitive inhibitor of the human immunoproteasome exhibiting preference for beta1i
Chem Biol Drug Des94, 1556-1567. PubMed Europe PubMed DOI I -
Ettari,R., Cerchia,C., Maiorana,S., Guccione,M., Novellino,E., Bitto,A., Grasso,S., Lavecchia,A. and Zappala,M.
Development of novel amides as noncovalent inhibitors of immunoproteasomes
ChemMedChem14, 842-852. PubMed Europe PubMed DOI I -
Scarpino,A., Bajusz,D., Proj,M., Gobec,M., Sosic,I., Gobec,S., Ferenczy,G.G. and Keseru,G.M.
Discovery of immunoproteasome inhibitors using large-scale covalent virtual screening
Molecules24, PubMed Europe PubMed DOI I -
Sun,C., Mo,M., Wang,Y., Yu,W., Song,C., Wang,X., Chen,S. and Liu,Y.
Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone
Neurotoxicology73, 112-119. PubMed Europe PubMed DOI -
Yeo,I.J., Lee,M.J., Baek,A., Miller,Z., Bhattarai,D., Baek,Y.M., Jeong,H.J., Kim,Y.K., Kim,D.E., Hong,J.T. and Kim,K.B.
A dual inhibitor of the proteasome catalytic subunits LMP2 and Y attenuates disease progression in mouse models of Alzheimer's disease
Sci Rep9, 18393-18393. PubMed Europe PubMed DOI I -
Basler,M., Maurits,E., de Bruin,G., Koerner,J., Overkleeft,H.S. and Groettrup,M.
Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome
Br J Pharmacol175, 38-52. PubMed Europe PubMed DOI I -
Basler,M., Lindstrom,M.M., LaStant,J.J., Bradshaw,J.M., Owens,T.D., Schmidt,C., Maurits,E., Tsu,C., Overkleeft,H.S., Kirk,C.J., Langrish,C.L. and Groettrup,M.
Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity
EMBO Rep19, e46512-e46512. PubMed Europe PubMed DOI I -
Chen,X., Zhang,X., Chen,T., Jiang,X., Wang,X., Lei,H. and Wang,Y.
Inhibition of immunoproteasome promotes angiogenesis via enhancing hypoxia-inducible factor-1alpha abundance in rats following focal cerebral ischaemia
Brain Behav Immun73, 167-179. PubMed Europe PubMed DOI I -
Zanker,D., Pang,K., Oveissi,S., Lu,C., Faou,P., Nowell,C., Mbogo,G.W., Carotta,S., Quillici,C., Karupiah,G., Hibbs,M.L., Nutt,S.L., Neeson,P., Puthalakath,H. and Chen,W.
LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins
Immunol Cell Biol96, 981-993. PubMed Europe PubMed DOI K -
Hewings,D.S., Flygare,J.A., Wertz,I.E. and Bogyo,M.
Activity-based probes for the multicatalytic proteasome
FEBS J284, 1540-1554. PubMed Europe PubMed DOI V L I -
Hovhannisyan,A.A., Pham,T.H., Bouvier,D., Tan,X., Touhar,S., Mkryan,G.G., Dallakyan,A.M., El Amri,C., Melikyan,G.S., Reboud-Ravaux,M. and Bouvier-Durand,M.
Phenoxypropanolamine derivatives as selective inhibitors of the 20S proteasome beta1 and beta5 subunits
Bioorg Med Chem Lett27, 5172-5178. PubMed Europe PubMed DOI I -
Johnson,H.W.B., Anderl,J.L., Bradley,E.K., Bui,J., Jones,J., Arastu-Kapur,S., Kelly,L.M., Lowe,E., Moebius,D.C., Muchamuel,T., Kirk,C., Wang,Z. and McMinn,D.
Discovery of highly selective inhibitors of the immunoproteasome low molecular mass polypeptide 2 (LMP2) subunit
ACS Med Chem Lett8, 413-417. PubMed Europe PubMed DOI I -
de Bruin,G., Xin,B.T., Kraus,M., van der Stelt,M., van der Marel,G.A., Kisselev,A.F., Driessen,C., Florea,B.I. and Overkleeft,H.S.
A set of activity-based probes to visualize human (immuno)proteasome activities
Angew Chem Int Ed Engl55, 4199-4203. PubMed Europe PubMed DOI A I -
Gvozdeva,O.V., Prassolov,V.S., Zenkova,M.A., Vlassov,V.V. and Chernolovskaya,E.L.
Silencing of inducible immunoproteasome subunit expression by chemically modified siRNA and shRNA
Nucleosides Nucleotides Nucleic Acids35, 389-403. PubMed Europe PubMed DOI K -
Kuzina,E.S., Kudriaeva,A.A., Maltseva,D.V. and Belogurov AA Jr
Peptidyl aldehyde specifically interacts with immunosubunit beta1i proteasome: in vitro and in vivo effects
Bull Exp Biol Med161, 69-71. PubMed Europe PubMed DOI I -
Beilstein,F., Obiang,L., Raux,H. and Gaudin,Y.
Characterization of the interaction between the matrix protein of vesicular stomatitis virus and the immunoproteasome subunit LMP2
J Virol89, 11019-11029. PubMed Europe PubMed DOI -
Brehm,A., Liu,Y., Sheikh,A., Marrero,B., Omoyinmi,E., Zhou,Q., Montealegre,G., Biancotto,A., Reinhardt,A., Almeida de Jesus,A., Pelletier,M., Tsai,W.L., Remmers,E.F., Kardava,L., Hill,S., Kim,H., Lachmann,H.J., Megarbane,A., Chae,J.J., Brady,J., Castillo,R.D., Brown,D., Casano,A.V., Gao,L., Chapelle,D., Huang,Y., Stone,D., Chen,Y., Sotzny,F., Lee,C.C., Kastner,D.L., Torrelo,A., Zlotogorski,A., Moir,S., Gadina,M., McCoy,P., Wesley,R., Rother,K., Hildebrand,P.W., Brogan,P., Kruger,E., Aksentijevich,I. and Goldbach-Mansky,R.
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production
J Clin Invest125, 4196-4211. PubMed Europe PubMed DOI M -
de Bruin,G., Huber,E.M., Xin,B.T., van Rooden,E.J., Al-Ayed,K., Kim,K.B., Kisselev,A.F., Driessen,C., van der Stelt,M., van der Marel,G.A., Groll,M. and Overkleeft,H.S.
Structure-based design of beta1i or beta5i specific inhibitors of human immunoproteasomes
J Med Chem57, 6197-6209. PubMed Europe PubMed DOI S I -
Hovhannisyan,A., Pham,T.H., Bouvier,D., Piroyan,A., Dufau,L., Qin,L., Cheng,Y., Melikyan,G., Reboud-Ravaux,M. and Bouvier-Durand,M.
New C(4)- and C(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform
Bioorg Med Chem Lett24, 1571-1580. PubMed Europe PubMed DOI I -
Dechavanne,V., Vilbois,F., Glez,L. and Antonsson,B.
Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC-MS
Protein Expr Purif87, 100-110. PubMed Europe PubMed DOI -
Miller,Z., Ao,L., Kim,K.B. and Lee,W.
Inhibitors of the immunoproteasome: current status and future directions
Curr Pharm Des19, 4140-4151. PubMed Europe PubMed I -
Park,J.E., Ao,L., Miller,Z., Kim,K., Wu,Y., Jang,E.R., Lee,E.Y., Kim,K.B. and Lee,W.
PSMB9 codon 60 polymorphisms have no impact on the activity of the immunoproteasome catalytic subunit B1i expressed in multiple types of solid cancer
PLoS ONE8, e73732-e73732. PubMed Europe PubMed DOI -
Tacchi,L., Misra,M. and Salinas,I.
Anti-viral immune responses in a primitive lung: Characterization and expression analysis of interferon-inducible immunoproteasome subunits LMP2, LMP7 and MECL-1 in a sarcopterygian fish, the Nigerian spotted lungfish (Protopterus dolloi)
Dev Comp Immunol41, 657-665. PubMed Europe PubMed DOI -
Basler,M. and Groettrup,M.
Immunoproteasome-specific inhibitors and their application
Methods Mol Biol832, 391-401. PubMed Europe PubMed DOI I -
Basler,M., Lauer,C., Moebius,J., Weber,R., Przybylski,M., Kisselev,A.F., Tsu,C. and Groettrup,M.
Why the structure but not the activity of the immunoproteasome subunit low molecular mass polypeptide 2 rescues antigen presentation
J Immunol189, 1868-1877. PubMed Europe PubMed DOI -
Grawert,M.A. and Groll,M.
Eukaryotic 20S proteasome
[ISSN:978-0-12-407742-3]3, 3684-3691. DOI -
Haroon,N., Maksymowych,W.P., Rahman,P., Tsui,F.W., O'Shea,F.D. and Inman,R.D.
Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the Spondyloarthritis Research Consortium of Canada cohort
Arthritis Rheum64, 1119-1126. PubMed Europe PubMed DOI M -
Wehenkel,M., Ban,J.O., Ho,Y.K., Carmony,K.C., Hong,J.T. and Kim,K.B.
A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice
Br J Cancer107, 53-62. PubMed Europe PubMed DOI I -
Hayashi,T., Horiuchi,A., Sano,K., Hiraoka,N., Kasai,M., Ichimura,T., Nagase,S., Ishiko,O., Shiozawa,T., Kanai,Y., Yaegashi,N., Aburatani,H., Tonegawa,S. and Konishi,I.
Involvement of proteasome beta1i subunit, LMP2, on development of uterin leiomyosarcma
North Am J Med Sci3, 394-399. PubMed Europe PubMed DOI -
Kuhn,D.J., Orlowski,R.Z. and Bjorklund,C.C.
Second generation proteasome inhibitors: carfilzomib and immunoproteasome-specific inhibitors (IPSIs)
Curr Cancer Drug Targets11, 285-295. PubMed Europe PubMed DOI I -
Lee,W. and Kim,K.B.
The immunoproteasome: an emerging therapeutic target
Curr Top Med Chem11, 2923-2930. PubMed Europe PubMed -
Sijts,E.J. and Kloetzel,P.M.
The role of the proteasome in the generation of MHC class I ligands and immune responses
Cell Mol Life Sci68, 1491-1502. PubMed Europe PubMed DOI V -
Hayashi,T., Horiuchi,A., Sano,K., Hiraoka,N., Kanai,Y., Shiozawa,T., Tonegawa,S. and Konishi,I.
Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma
Protein Cell1, 711-717. PubMed Europe PubMed DOI K -
Lei,B., Abdul Hameed,M.D.M., Hamza,A., Wehenkel,M., Muzyka,J.L., Yao,X.J., Kim,K.B. and Zhan,C.G.
Molecular basis of the selectivity of the immunoproteasome catalytic subunit LMP2-specific inhibitor revealed by molecular modeling and dynamics simulations
J Phys Chem B114, 12333-12339. PubMed Europe PubMed DOI I -
Kuhn,D.J., Hunsucker,S.A., Chen,Q., Voorhees,P.M., Orlowski,M. and Orlowski,R.Z.
Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors
Blood113, 4667-4676. PubMed Europe PubMed DOI I -
Ho,Y.K., Bargagna-Mohan,P., Wehenkel,M., Mohan,R. and Kim,K.B.
LMP2-Specific inhibitors: chemical genetic tools for proteasome biology
Chem Biol14, 419-430. PubMed Europe PubMed DOI I -
[YEAR:1-6-2006]Areste,C. and Blackbourn,D.J.
HIV Tat-mediated transcriptional regulation of proteasome protein cleavage specificity
Biochem J396, e13-e15. PubMed Europe PubMed DOI -
Ding,Q., Martin,S., Dimayuga,E., Bruce-Keller,A.J. and Keller,J.N.
LMP2 knock-out mice have reduced proteasome activities and increased levels of oxidatively damaged proteins
Antioxid Redox Signal8, 130-135. PubMed Europe PubMed DOI K -
[YEAR:15-9-2004]Basler,M., Youhnovski,N., Van Den Broek,M., Przybylski,M. and Groettrup,M.
Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus
J Immunol173, 3925-3934. PubMed Europe PubMed -
Seemuller,E., Dolenc,I. and Lupas,A.
Eukaryotic 20S proteasome
[ISSN:0-12-079610-4]2, 2068-2077. V -
Kesmir,C., van Noort,V., de Boer,R.J. and Hogeweg,P.
Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome
Immunogenetics55, 437-449. PubMed Europe PubMed DOI -
Kruger,E., Kuckelkorn,U., Sijts,A. and Kloetzel,P.M.
The components of the proteasome system and their role in MHC class I antigen processing
Rev Physiol Biochem Pharmacol148, 81-104. PubMed Europe PubMed DOI -
[YEAR:15-9-2002]Singh,S., Awasthi,N., Egwuagu,C.E. and Wagner,B.J.
Immunoproteasome expression in a nonimmune tissue, the ocular lens
Arch Biochem Biophys405, 147-153. PubMed Europe PubMed DOI -
Unno,M., Mizushima,T., Morimoto,Y., Tomisugi,Y., Tanaka,K., Yasuoka,N. and Tsukihara,T.
The structure of the mammalian 20S proteasome at 2.75 A resolution
Structure10, 609-618. PubMed Europe PubMed DOI S -
[YEAR:2-7-2001]Toes,R.E., Nussbaum,A.K., Degermann,S., Schirle,M., Emmerich,N.P., Kraft,M., Laplace,C., Zwinderman,A., Dick,T.P., Muller,J., Schonfisch,B., Schmid,C., Fehling,H.J., Stevanovic,S., Rammensee,H.G. and Schild,H.
Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
J Exp Med194, 1-12. PubMed Europe PubMed DOI -
[YEAR:15-10-2000]Clark,M.S., Pontarotti,P., Gilles,A., Kelly,A. and Elgar,G.
Identification and characterization of a beta proteasome subunit cluster in the Japanese pufferfish (Fugu rubripes)
J Immunol165, 4446-4452. PubMed Europe PubMed -
[YEAR:4-8-2000]Kingsbury,D.J., Griffin,T.A. and Colbert,R.A.
Novel propeptide function in 20 S proteasome assembly influences beta subunit composition
J Biol Chem275, 24156-24162. PubMed Europe PubMed DOI -
[YEAR:19-5-2000]Kisselev,A.F., Songyang,Z. and Goldberg,A.L.
Why does threonine, and not serine, function as the active site nucleophile in proteasomes?
J Biol Chem275, 14831-14837. PubMed Europe PubMed DOI I -
[YEAR:15-7-2000]Schwarz,K., Van Den Broek,M., Kostka,S., Kraft,R., Soza,A., Schmidtke,G., Kloetzel,P.M. and Groettrup,M.
Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope
J Immunol165, 768-778. PubMed Europe PubMed -
[YEAR:5-1-1998]Griffin,T.A., Nandi,D., Cruz,M., Fehling,H.J., Van Kaer,L., Monaco,J.J. and Colbert,R.A.
Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits
J Exp Med187, 97-104. PubMed Europe PubMed DOI -
Eleuteri,A.M., Kohanski,R.A., Cardozo,C. and Orlowski,M.
Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity
J Biol Chem272, 11824-11831. PubMed Europe PubMed DOI -
Hughes,A.L.
Evolution of the proteasome components
Immunogenetics46, 82-92. PubMed Europe PubMed DOI -
Nonaka,M., Namikawa-Yamada,C., Sasaki,M., Salter-Cid,L. and Flajnik,M.F.
Evolution of proteasome subunits delta and LMP2: complementary DNA cloning and linkage analysis with MHC in lower vertebrates
J Immunol159, 734-740. PubMed Europe PubMed -
Coux,O., Tanaka,K. and Goldberg,A.L.
Structure and functions of the 20S and 26S proteasomes
Annu Rev Biochem65, 801-847. PubMed Europe PubMed DOI -
[YEAR:6-10-1995]Groettrup,M., Ruppert,T., Kuehn,L., Seeger,M., Standera,S., Koszinowski,U. and Kloetzel,P.M.
The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro
J Biol Chem270, 23808-23815. PubMed Europe PubMed DOI -
Sibille,C., Gould,K.G., Willard-Gallo,K., Thomson,S., Rivett,A.J., Powis,S., Butcher,G.W. and De Baetselier,P.
LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes
Curr Biol5, 923-930. PubMed Europe PubMed K -
Woodward,E.C. and Monaco,J.J.
Characterization and mapping of the gene encoding mouse proteasome subunit DELTA (Lmp19)
Immunogenetics42, 28-34. PubMed Europe PubMed DOI
2024
2023
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2007
2006
2004
2003
2002
2001
2000
1998
1997
1996
1995
