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Literature for peptidase T01.006: HslV component of HslUV peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, K Knockout, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Hamid,M., Salar,U., Rashid,Y., Azim,M.K., Khan,K.M., Naz,S., Aziz,T., Alharbi,M., Alshammari,A. and Alasmari,A.F.
    Determining the 3-substituted Coumarins inhibitory potential against the HslV protease of E. coli
    Eur Rev Med Pharmacol Sci27, 9169-9182. PubMed  Europe PubMed DOI  I
    2. 2019
  2. Chang,C.Y., Weng,Y.T., Hwang,L.Y., Hu,H.T., Shih,P.S., Kuan,J.E., Wu,K.F. and Wu,W.F.
    Specific regions of the SulA protein recognized and degraded by the ATP-dependent ClpYQ (HslUV) protease in Escherichia coli
    Microbiol Res220, 21-31. PubMed  Europe PubMed DOI
  3. Fuchs,A.C.D. and Hartmann,M.D.
    On the origins of symmetry and modularity in the proteasome family: symmetry transitions are pivotal in the evolution and functional diversification of self-compartmentalizing proteases
    Bioessayse1800237-e1800237. PubMed  Europe PubMed DOI
    4. 2018
  4. Yu,Y., Yan,F., He,Y., Qin,Y., Chen,Y., Chai,Y. and Guo,J.H.
    The ClpY-ClpQ protease regulates multicellular development in Bacillus subtilis
    Microbiology (Reading)164, 848-862. PubMed  Europe PubMed DOI
    5. 2017
  5. Baytshtok,V., Chen,J., Glynn,S.E., Nager,A.R., Grant,R.A., Baker,T.A. and Sauer,R.T.
    Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation
    J Biol Chem292, 5695-5704. PubMed  Europe PubMed DOI
  6. Dong,S.L., Hu,W.L., Ge,Y.M., Ojcius,D.M., Lin,X. and Yan,J.
    A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis
    Emerg Microbes Infect6, e105-e105. PubMed  Europe PubMed DOI
  7. Tsai,C.H., Ho,Y.H., Sung,T.C., Wu,W.F. and Chen,C.S.
    Escherichia coli proteome microarrays identified the substrates of ClpYQ protease
    Mol Cell Proteomics16, 113-120. PubMed  Europe PubMed DOI  P
    8. 2016
  8. Chang,C.Y., Hu,H.T., Tsai,C.H. and Wu,W.F.
    The degradation of RcsA by ClpYQ(HslUV) protease in Escherichia coli
    Microbiol Res184, 42-50. PubMed  Europe PubMed DOI
    9. 2014
  9. Hwang,L.-Y., Hu,H.-T., Tsai,C.-H. and Wu,W.-F.
    The Escherichia coli ClpYQ protease recognizes the C-terminal tail of SulA
    Taiwanese J Agric Chem Food Sci52, 48-58.  P
  10. Shi,L. and Kay,L.E.
    Tracing an allosteric pathway regulating the activity of the HslV protease
    Proc Natl Acad Sci U S A111, 2140-2145. PubMed  Europe PubMed DOI
    11. 2013
  11. Jain,S., Rathore,S., Asad,M., Hossain,M.E., Sinha,D., Datta,G. and Mohmmed,A.
    The prokaryotic ClpQ protease plays a key role in growth and development of mitochondria in Plasmodium falciparum
    Cell Microbiol15, 1660-1673. PubMed  Europe PubMed DOI
  12. Park,E., Lee,J.W., Yoo,H.M., Ha,B.H., An,J.Y., Jeon,Y.J., Seol,J.H., Eom,S.H. and Chung,C.H.
    Structural alteration in the pore motif of the bacterial 20S proteasome homolog HslV leads to uncontrolled protein degradation
    J Mol Biol425, 2940-2954. PubMed  Europe PubMed DOI
    13. 2012
  13. Chrobak,M., Forster,S., Meisel,S., Pfefferkorn,R., Forster,F. and Clos,J.
    Leishmania donovani HslV does not interact stably with HslU proteins
    Int J Parasitol42, 329-339. PubMed  Europe PubMed DOI
  14. Park,E., Yoo,S.J., Seong,I.S., Goldberg,A.L. and Chung,C.H.
    HslVU protease
    [ISSN:978-0-12-407742-3]3, 3677-3683. DOI
  15. Rashid,Y., Kamran Azim,M., Saify,Z.S., Khan,K.M. and Khan,R.
    Small molecule activators of proteasome-related HslV peptidase
    Bioorg Med Chem Lett22, 6089-6094. PubMed  Europe PubMed DOI  I
  16. Sundar,S., Baker,T.A. and Sauer,R.T.
    The I domain of the AAA+ HslUV protease coordinates substrate binding, ATP hydrolysis, and protein degradation
    Protein Sci21, 188-198. PubMed  Europe PubMed DOI
    17. 2011
  17. Rathore,S., Jain,S., Sinha,D., Gupta,M., Asad,M., Srivastava,A., Narayanan,M.S., Ramasamy,G., Chauhan,V.S., Gupta,D. and Mohmmed,A.
    Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death
    Cell Death Dis2, e231-e231. PubMed  Europe PubMed DOI
  18. Sauer,R.T. and Baker,T.A.
    AAA+ Proteases: ATP-fueled machines of protein destruction
    Annu Rev Biochem80, 587-612. PubMed  Europe PubMed DOI
    19. 2010
  19. Sundar,S., McGinness,K.E., Baker,T.A. and Sauer,R.T.
    Multiple sequence signals direct recognition and degradation of protein substrates by the AAA+ protease HslUV
    J Mol Biol403, 420-429. PubMed  Europe PubMed DOI  P
    20. 2009
  20. Koodathingal,P., Jaffe,N.E., Kraut,D.A., Prakash,S., Fishbain,S., Herman,C. and Matouschek,A.
    ATP-dependent proteases differ substantially in their ability to unfold globular proteins
    J Biol Chem284, 18674-18684. PubMed  Europe PubMed DOI
  21. Lee,J.W., Park,E., Jeong,M.S., Jeon,Y.J., Eom,S.H., Seol,J.H. and Chung,C.H.
    HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis
    J Biol Chem284, 33475-33484. PubMed  Europe PubMed DOI
    22. 2008
  22. Inobe,T. and Matouschek,A.
    Protein targeting to ATP-dependent proteases
    Curr Opin Struct Biol18, 43-51. PubMed  Europe PubMed DOI  V
  23. Park,E., Lee,J.W., Eom,S.H., Seol,J.H. and Chung,C.H.
    Binding of MG132 or deletion of the Thr active sites in HslV subunits increases the affinity of HslV protease for HslU ATPase and makes this interaction nucleotide-independent
    J Biol Chem283, 33258-33266. PubMed  Europe PubMed DOI  I
  24. Yakamavich,J.A., Baker,T.A. and Sauer,R.T.
    Asymmetric nucleotide transactions of the HslUV protease
    J Mol Biol380, 946-957. PubMed  Europe PubMed DOI
    25. 2007
  25. Azim,M.K. and Noor,S.
    Characterization of protomer interfaces in HslV protease; the bacterial homologue of 20S proteasome
    Protein J26, 213-219. PubMed  Europe PubMed DOI
  26. Lee,J.W., Park,E., Bang,O., Eom,S.H., Cheong,G.W., Chung,C.H. and Seol,J.H.
    Nucleotide triphosphates inhibit the degradation of unfolded proteins by HslV peptidase
    Mol Cells23, 252-257. PubMed  Europe PubMed
    27. 2006
  27. [YEAR:4-10-2006]Ruiz-Gonzalez,M.X. and Marin,I.
    Proteasome-related HslU and HslV genes typical of eubacteria are widespread in eukaryotes
    J Mol Evol63, 504-512. PubMed  Europe PubMed DOI
    28. 2005
  28. Azim,M.K., Goehring,W., Song,H.K., Ramachandran,R., Bochtler,M. and Goettig,P.
    Characterization of the HsIU chaperone affinity for HsIV protease (vol 14, pg 1357, 2005)
    Protein Sci14, 2484-2484. PubMed  Europe PubMed DOI
  29. [YEAR:31-3-2005]Azim,M.K., Goehring,W., Song,H.K., Ramachandran,R., Bochtler,M. and Goettig,P.
    Characterization of the HslU chaperone affinity for HslV protease
    Protein Sci14, 1357-1362. PubMed  Europe PubMed DOI
  30. [YEAR:6-2-2005]Burton,R.E., Baker,T.A. and Sauer,R.T.
    Nucleotide-dependent substrate recognition by the AAA+ HslUV protease
    Nat Struct Mol Biol12, 245-251. PubMed  Europe PubMed DOI
  31. [YEAR:21-4-2005]Frees,D., Thomsen,L.E. and Ingmer,H.
    Staphylococcus aureus ClpYQ plays a minor role in stress survival
    Arch Microbiol183, 286-291. PubMed  Europe PubMed DOI  K
  32. [YEAR:22-4-2005]Park,E., Rho,Y.M., Koh,O.J., Ahn,S.W., Seong,I.S., Song,J.J., Bang,O., Seol,J.H., Wang,J., Eom,S.H. and Chung,C.H.
    Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase
    J Biol Chem280, 22892-22898. PubMed  Europe PubMed DOI
  33. Wang,J., Rho,S.H., Park,H.H. and Eom,S.H.
    Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects
    Acta Crystallogr D Biol Crystallogr61, 932-941. PubMed  Europe PubMed DOI  S
    34. 2004
  34. Huang,H.C., Goldberg,A.L., Yoo,S.J., Seong,I.S. and Chung,C.H.
    HslVU protease
    [ISSN:0-12-079610-4]2, 2064-2068.  V
  35. Kwon,A.R., Trame,C.B. and McKay,D.B.
    Kinetics of protein substrate degradation by HslUV
    J Struct Biol146, 141-147. PubMed  Europe PubMed DOI
    36. 2003
  36. [YEAR:4-7-2003]Kwon,A.R., Kessler,B.M., Overkleeft,H.S. and McKay,D.B.
    Structure and reactivity of an asymmetric complex between HslV and I-domain deleted HslU, a prokaryotic homolog of the eukaryotic proteasome
    J Mol Biol330, 185-195. PubMed  Europe PubMed DOI
  37. Lee,Y.Y., Chang,C.F., Kuo,C.L., Chen,M.C., Yu,C.H., Lin,P.I. and Wu,W.F.
    Subunit oligomerization and substrate recognition of the Escherichia coli ClpYQ (HslUV) protease implicated by in vivo protein-protein interactions in the yeast two-hybrid system
    J Bacteriol185, 2393-2401. PubMed  Europe PubMed DOI
  38. [YEAR:23-10-2003]Nishii,W. and Takahashi,K.
    Determination of the cleavage sites in SulA, a cell division inhibitor, by the ATP-dependent HslVU protease from Escherichia coli
    FEBS Lett553, 351-354. PubMed  Europe PubMed DOI
    39. 2002
  39. [YEAR:28-5-2002]Ramachandran,R., Hartmann,C., Song,H.K., Huber,R. and Bochtler,M.
    Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)
    Proc Natl Acad Sci U S A99, 7396-7401. PubMed  Europe PubMed DOI
  40. [YEAR:19-7-2002]Seong,I.S., Kang,M.S., Choi,M.K., Lee,J.W., Koh,O.J., Wang,J., Eom,S.H. and Chung,C.H.
    The C-terminal tails of HslU ATPase act as a molecular switch for activation of HslV peptidase
    J Biol Chem277, 25976-25982. PubMed  Europe PubMed DOI
  41. [YEAR:3-5-2002]Sousa,M.C., Kessler,B.M., Overkleeft,H.S. and McKay,D.B.
    Crystal structure of HslUV complexed with a vinyl sulfone inhibitor: corroboration of a proposed mechanism of allosteric activation of HslV by HslU
    J Mol Biol318, 779-785. PubMed  Europe PubMed DOI  S  I
    42. 2001
  42. Bochtler,M., Song,H.K., Hartmann,C., Ramachandran,R. and Huber,R.
    The quaternary arrangement of HslU and HslV in a cocrystal: a response to Wang, Yale
    J Struct Biol135, 281-293. PubMed  Europe PubMed DOI  S
  43. Sousa,M.C. and McKay,D.B.
    Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site
    Acta Crystallogr D Biol Crystallogr57, 1950-1954. PubMed  Europe PubMed DOI
  44. Wang,J.
    A corrected quaternary arrangement of the peptidase HslV and ATPase HslU in a cocrystal structure
    J Struct Biol134, 15-24. PubMed  Europe PubMed DOI  S
  45. Wang,J., Song,J.J., Franklin,M.C., Kamtekar,S., Im,Y.J., Rho,S.H., Seong,I.S., Lee,C.S., Chung,C.H. and Eom,S.H.
    Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism
    Structure9, 177-184. PubMed  Europe PubMed DOI  S
    46. 2000
  46. [YEAR:17-2-2000]Bochtler,M., Hartmann,C., Song,H.K., Bourenkov,G.P., Bartunik,H.D. and Huber,R.
    The structures of HsIU and the ATP-dependent protease HsIU-HsIV
    Nature403, 800-805. PubMed  Europe PubMed DOI  S
  47. [YEAR:21-7-2000]Seong,I.S., Oh,J.Y., Lee,J.W., Tanaka,K. and Chung,C.H.
    The HslU ATPase acts as a molecular chaperone in prevention of aggregation of SulA, an inhibitor of cell division in Escherichia coli
    FEBS Lett477, 224-229. PubMed  Europe PubMed DOI
  48. [YEAR:10-11-2000]Sousa,M.C., Trame,C.B., Tsuruta,H., Wilbanks,S.M., Reddy,V.S. and McKay,D.B.
    Crystal and solution structures of an HslUV protease-chaperone complex
    Cell103, 633-643. PubMed  Europe PubMed  S
    49. 1999
  49. Kanemori,M., Yanagi,H. and Yura,T.
    The ATP-dependent HslVU/ClpQY protease participates in turnover of cell division inhibitor SulA in Escherichia coli
    J Bacteriol181, 3674-3680. PubMed  Europe PubMed
  50. Schmidt,M., Lupas,A.N. and Finley,D.
    Structure and mechanism of ATP-dependent proteases
    Curr Opin Chem Biol3, 584-591. PubMed  Europe PubMed DOI
  51. [YEAR:30-7-1999]Seong,I.S., Oh,J.Y., Yoo,S.J., Seol,J.H. and Chung,C.H.
    ATP-dependent degradation of SulA, a cell division inhibitor, by the HslVU protease in Escherichia coli
    FEBS Lett456, 211-214. PubMed  Europe PubMed DOI
  52. Wu,W.F., Zhou,Y. and Gottesman,S.
    Redundant in vivo proteolytic activities of Escherichia coli lon and the ClpYQ (HslUV) protease
    J Bacteriol181, 3681-3687. PubMed  Europe PubMed
    53. 1998
  53. [YEAR:2-1-1998]Hilliard,J.J., Maurizi,M.R. and Simon,L.D.
    Isolation and characterization of the phage T4 PinA protein, an inhibitor of the ATP-dependent Lon protease of Escherichia coli
    J Biol Chem273, 518-523. PubMed  Europe PubMed DOI
  54. [YEAR:4-9-1998]Yoo,S.J., Kim,H.H., Shin,D.H., Lee,C.S., Seong,I.S., Seol,J.H., Shimbara,N., Tanaka,K. and Chung,C.H.
    Effects of the Cys mutations on structure and function of the ATP-dependent HslVU protease in Escherichia coli. The Cys287 to Val mutation in HslU uncouples the ATP-dependent proteolysis by HslVU from ATP hydrolysis
    J Biol Chem273, 22929-22935. PubMed  Europe PubMed DOI
    55. 1997
  55. [YEAR:10-6-1997]Bochtler,M., Ditzel,L., Groll,M. and Huber,R.
    Crystal structure of heat shock locus V (HslV) from Escherichia coli
    Proc Natl Acad Sci U S A94, 6070-6074. PubMed  Europe PubMed DOI
  56. [YEAR:24-6-1997]Bogyo,M., McMaster,J.S., Gaczynska,M., Tortorella,D., Goldberg,A.L. and Ploegh,H.
    Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors
    Proc Natl Acad Sci U S A94, 6629-6634. PubMed  Europe PubMed  I
  57. Goldberg,A.L., Akopian,T.N., Kisselev,A.F., Lee,D.H. and Rohrwild,M.
    New insights into the mechanisms and importance of the proteasome in intracellular protein degradation
    Biol Chem378, 131-140. PubMed  Europe PubMed
  58. [YEAR:22-8-1997]Huang,H. and Goldberg,A.L.
    Proteolytic activity of the ATP-dependent protease HslVU can be uncoupled from ATP hydrolysis
    J Biol Chem272, 21364-21372. PubMed  Europe PubMed DOI
  59. Khattar,M.M.
    Overexpression of the hslVU operon suppresses SOS-mediated inhibition of cell division in Escherichia coli
    FEBS Lett414, 402-404. PubMed  Europe PubMed DOI
  60. Rohrwild,M., Pfeifer,G., Santarius,U., Muller,S.A., Huang,H.C., Engel,A., Baumeister,W. and Goldberg,A.L.
    The ATP-dependent HslVU protease from Escherichia coli is a four-ring structure resembling the proteasome
    Nat Struct Biol4, 133-139. PubMed  Europe PubMed DOI  S
  61. Yoo,S.J., Shim,Y.K., Seong,I.S., Seol,J.H., Kang,M.S. and Chung,C.H.
    Mutagenesis of two N-terminal Thr and five Ser residues in HslV, the proteolytic component of the ATP-dependent HslVU protease
    FEBS Lett412, 57-60. PubMed  Europe PubMed DOI
    62. 1996
  62. Kessel,M., Wu,W., Gottesman,S., Kocsis,E., Steven,A.C. and Maurizi,M.R.
    Six-fold rotational symmetry of ClpQ, the E. coli homolog of the 20S proteasome, and its ATP-dependent activator, ClpY
    FEBS Lett398, 274-278. PubMed  Europe PubMed DOI
  63. Missiakas,D., Schwager,F., Betton,J.M., Georgopoulos,C. and Raina,S.
    Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli
    EMBO J15, 6899-6909. PubMed  Europe PubMed
  64. Rohrwild,M., Coux,O., Huang,H.C., Moerschell,R.P., Yoo,S.J., Seol,J.H., Chung,C.H. and Goldberg,A.L.
    HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome
    Proc Natl Acad Sci U S A93, 5808-5813. PubMed  Europe PubMed
  65. Shin,D.H., Yoo,S.J., Shim,Y.K., Seol,J.H., Kang,M.S. and Chung,C.H.
    Mutational analysis of the ATP-binding site in HslU, the ATPase component of HslVU protease in Escherichia coli
    FEBS Lett398, 151-154. PubMed  Europe PubMed DOI
  66. Yoo,S.J., Seol,J.H., Shin,D.H., Rohrwild,M., Kang,M.S., Tanaka,K., Goldberg,A.L. and Chung,C.H.
    Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli
    J Biol Chem271, 14035-14040. PubMed  Europe PubMed DOI
  67. Yoo,S.J., Seol,J.H., Kang,M.S. and Chung,C.H.
    Poly-L-lysine activates both peptide and ATP hydrolysis by the ATP-dependent HslVU protease in Escherichia coli
    Biochem Biophys Res Commun229, 531-535. PubMed  Europe PubMed DOI
    68. 1995
  68. Gottesman,S., Wickner,S., Jubete,Y., Singh,S.K., Kessel,M. and Maurizi,M.
    Selective, energy-dependent proteolysis in Escherichia coli
    Cold Spring Harb Symp Quant Biol60, 533-548. PubMed  Europe PubMed
    69. 1993
  69. [YEAR:30-11-1993]Chuang,S.E., Burland,V., Plunkett,G., III, Daniels,D.L. and Blattner,F.R.
    Sequence analysis of four new heat-shock genes constituting the hslTS/ibpAB and hslVU operons in Escherichia coli
    Gene134, 1-6. PubMed  Europe PubMed DOI
  70. [YEAR:25-10-1993]Gottesman,S., Clark,W.P., de Crecy-Lagard,V. and Maurizi,M.R.
    ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities
    J Biol Chem268, 22618-22626. PubMed  Europe PubMed

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