Literature for peptidase S54.006: rhomboid like 3 peptidase (Homo sapiens)

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2025
1. Bhaduri,S., Braza,M.K.E., Stanchev,S., Tauber,M., Al-Bawab,R., Liu,L.J., Trujillo,D.F., Solorio-Kirpichyan,K., Srivastava,A., Sanlley-Hernandez,J., O'Donoghue,A.J., Lemberg,M.K., Amaro,R., Strisovsky,K. and Neal,S.E.
   An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
   J Biol Chem108275-108275. PubMed  Europe PubMed DOI
2. Penalva,Y.C.M., Paschkowsky,S., Yang,J., Recinto,S.J., Cinkornpumin,J.K., Ruelas,M., Xiao,B., Nitu,A., Kwon,S.Y., Wu,H.Y., Munter,H.M., Michalski,B., Fahnestock,M., Pastor,W.A., Bennett,D.A. and Munter,L.M.
   Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model
   Cell Death Dis16, 280-280. PubMed  Europe PubMed DOI
2024
3. Bhaduri,S., Braza,M.K.E., Stanchev,S., Tauber,M., Al-Bawab,R., Liu,L.J., Trujillo,D.F., Solorio-Kirpichyan,K., Srivastava,A., Sanlley-Hernandez,J., O'Donoghue,A.J., Lemberg,M.K., Amario,R., Strisovsky,K. and Neal,S.E.
   An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
   bioRxiv PubMed  Europe PubMed DOI
4. Knopf,J.D., Steigleder,S.S., Korn,F., Kuhnle,N., Badenes,M., Tauber,M., Theobald,S.J., Rybniker,J., Adrain,C. and Lemberg,M.K.
   RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling
   Nat Commun15, 1528-1528. PubMed  Europe PubMed DOI
5. Penalva,Y.C.M., Paschkowsky,S., Recinto,S.J., Duchesne,A., Hammond,T., Spiegler,P., Jansen,G., Levet,C., Charron,F., Freeman,M., McKinney,R.A., Trempe,J.F. and Munter,L.M.
   Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4
   J Biol Chem107541-107541. PubMed  Europe PubMed DOI
6. Penalva,Y.C.M., Paschkowsky,S., Yang,J., Recinto,S.J., Cinkorpumin,J., Xiao,B., Nitu,A., Wu,H., Munter,H.M., Michalski,B., Fahnestock,M., Pastor,W., Bennett,D.A. and Munter,L.M.
   Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model
   bioRxiv PubMed  Europe PubMed DOI
2022
7. Lastun,V.L., Levet,C. and Freeman,M.
   The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets
   J Biol Chem298, 101935-101935. PubMed  Europe PubMed DOI
8. Shibuya,K., Ebihara,K., Ebihara,C., Sawayama,N., Isoda,M., Yamamuro,D., Takahashi,M., Nagashima,S. and Ishibashi,S.
   AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4
   J Biol Chem298, 101936-101936. PubMed  Europe PubMed DOI  K
2020
9. Knopf,J.D., Landscheidt,N., Pegg,C.L., Schulz,B.L., Kuhnle,N., Chao,C.W., Huck,S. and Lemberg,M.K.
   Intramembrane protease RHBDL4 cleaves oligosaccharyltransferase subunits to target them for ER-associated degradation
   J Cell Sci PubMed  Europe PubMed DOI
2019
10. Ikeda,K.N. and Freeman,M.
    Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4
    J Biol Chem294, 11486-11497. PubMed  Europe PubMed DOI
2018
11. Paschkowsky,S., Recinto,S.J., Young,J.C., Bondar,A.N. and Munter,L.M.
    Membrane cholesterol as regulator of human rhomboid protease RHBDL4
    J Biol Chem293, 15556-15568. PubMed  Europe PubMed DOI
2016
12. Lim,J.J., Lee,Y., Ly,T.T., Kang,J.Y., Lee,J.G., An,J.Y., Youn,H.S., Park,K.R., Kim,T.G., Yang,J.K., Jun,Y. and Eom,S.H.
    Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4
    Biochem J473, 2863-2880. PubMed  Europe PubMed DOI
13. Paschkowsky,S., Hamze,M., Oestereich,F. and Munter,L.M.
    Alternative processing of the amyloid precursor protein family by rhomboid protease RHBDL4
    J Biol Chem291, 21903-21912. PubMed  Europe PubMed DOI
14. Wunderle,L., Knopf,J.D., Kuhnle,N., Morle,A., Hehn,B., Adrain,C., Strisovsky,K., Freeman,M. and Lemberg,M.K.
    Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFalpha
    Sci Rep6, 27342-27342. PubMed  Europe PubMed DOI
2013
15. Kumar,A., Gibbs,J.R., Beilina,A., Dillman,A., Kumaran,R., Trabzuni,D., Ryten,M., Walker,R., Smith,C., Traynor,B.J., Hardy,J., Singleton,A.B. and Cookson,M.R.
    Age-associated changes in gene expression in human brain and isolated neurons
    Neurobiol Aging34, 1199-1209. PubMed  Europe PubMed DOI
2012
16. Fleig,L., Bergbold,N., Sahasrabudhe,P., Geiger,B., Kaltak,L. and Lemberg,M.K.
    Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins
    Mol Cell47, 558-569. PubMed  Europe PubMed DOI
17. Greenblatt,E.J., Olzmann,J.A. and Kopito,R.R.
    Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD
    Nat Struct Mol Biol19, 979-981. PubMed  Europe PubMed DOI
18. Tsai,Y.C. and Weissman,A.M.
    A ubiquitin-binding rhomboid protease aimed at ERADication
    Dev Cell23, 454-456. PubMed  Europe PubMed DOI
19. Urban,S.
    Mammalian rhomboid proteases
    [ISSN:978-0-12-407742-3]3, 3573-3581. DOI
2002
20. Jaszai,J. and Brand,M.
    Cloning and expression of Ventrhoid, a novel vertebrate homologue of the Drosophila EGF pathway gene rhomboid
    Mech Dev113, 73-77. PubMed  Europe PubMed