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Literature for peptidase S24.003: UmuD protein

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Candra,B., Cook,D. and Hare,J.
    Repression of Acinetobacter baumannii DNA damage response requires DdrR-assisted binding of UmuDAb dimers to atypical SOS box
    J Bacteriol (2024) , e0043223-e0043223. PubMed  Europe PubMed DOI
    2. 2023
  2. Cook,D., Flannigan,M.D., Chariker,J.H. and Hare,J.M.
    DNA damage response coregulator ddrR affects many cellular pathways and processes in Acinetobacter baumannii 17978
    Front Cell Infect Microbiol (2023) 13, 1324091-1324091. PubMed  Europe PubMed DOI  PMC  EPMC
  3. Gao,B., Liang,L., Su,L., Wen,A., Zhou,C. and Feng,Y.
    Structural basis for regulation of SOS response in bacteria
    Proc Natl Acad Sci U S A (2023) 120, e2217493120-e2217493120. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2022
  4. Cook,D., Flannigan,M.D., Candra,B.V., Compton,K.D. and Hare,J.M.
    The DdrR Coregulator of the Acinetobacter baumannii Mutagenic DNA Damage Response Potentiates UmuDAb Repression of Error-Prone Polymerases
    J Bacteriol (2022) 204, e0016522-e0016522. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Gregg-Jolly,L.A.
    Locking down SOS Mutagenesis Repression in a Dynamic Pathogen
    J Bacteriol (2022) 204, e0022022-e0022022. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Pavlin,A., Bajc,G., Fornelos,N., Browning,D.F. and Butala,M.
    The Small DdrR Protein Directly Interacts with the UmuDAb Regulator of the Mutagenic DNA Damage Response in Acinetobacter baumannii
    J Bacteriol (2022) 204, e0060121-e0060121. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2021
  7. Henrikus,S.S., van Oijen,A.M. and Robinson,A.
    Single-molecule fluorescence microscopy reveals modulation of DNA polymerase IV-binding lifetimes by UmuD (K97A) and UmuD'
    Curr Genet (2021) PubMed  Europe PubMed DOI
    8. 2020
  8. Jin,H., Kim,R. and Bhaya,D.
    Deciphering proteolysis pathways for the error-prone DNA polymerase in cyanobacteria
    Environ Microbiol (2020) PubMed  Europe PubMed DOI
    9. 2017
  9. Murison,D.A., Ollivierre,J.N., Huang,Q., Budil,D.E. and Beuning,P.J.
    Altering the N-terminal arms of the polymerase manager protein UmuD modulates protein interactions
    PLoS ONE (2017) 12, e0173388-e0173388. PubMed  Europe PubMed DOI
  10. Murison,D.A., Timson,R.C., Koleva,B.N., Ordazzo,M. and Beuning,P.J.
    Identification of the dimer exchange interface of the bacterial DNA damage response protein UmuD
    Biochemistry (2017) 56, 4773-4785. PubMed  Europe PubMed DOI
    11. 2013
  11. Chandani,S. and Loechler,E.L.
    Structural model of the Y-family DNA polymerase V/RecA mutasome
    J Mol Graph Model (2013) 39, 133-144. PubMed  Europe PubMed DOI
  12. Ollivierre,J.N., Sikora,J.L. and Beuning,P.J.
    Dimer exchange and cleavage specificity of the DNA damage response protein UmuD
    Biochim Biophys Acta (2013) 1834, 611-620. PubMed  Europe PubMed DOI
    13. 2012
  13. Hare,J.M., Adhikari,S., Lambert,K.V., Hare,A.E. and Grice,A.N.
    The Acinetobacter regulatory UmuDAb protein cleaves in response to DNA damage with chimeric LexA/UmuD characteristics
    FEMS Microbiol Lett (2012) 334, 57-65. PubMed  Europe PubMed DOI
  14. Paetzel,M. and Woodgate,R.
    UmuD and UmuD' proteins
    [ISSN:978-0-12-407742-3] (2012) 3, 3487-3492. DOI
    15. 2011
  15. Ollivierre,J.N., Sikora,J.L. and Beuning,P.J.
    The dimeric SOS mutagenesis protein UmuD is active as a monomer
    J Biol Chem (2011) 286, 3607-3617. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Ollivierre,J.N., Budil,D.E. and Beuning,P.J.
    Electron spin labeling reveals the highly dynamic N-terminal arms of the SOS mutagenesis protein UmuD
    Mol Biosyst (2011) 7, 3183-3186. PubMed  Europe PubMed DOI  S
    17. 2010
  17. Fang,J., Rand,K.D., Silva,M.C., Wales,T.E., Engen,J.R. and Beuning,P.J.
    Conformational dynamics of the Escherichia coli DNA polymerase manager proteins UmuD and UmuD'
    J Mol Biol (2010) 398, 40-53. PubMed  Europe PubMed DOI
    18. 2009
  18. Beuning,P.J., Chan,S., Waters,L.S., Addepalli,H., Ollivierre,J.N. and Walker,G.C.
    Characterization of novel alleles of the Escherichia coli umuDC genes identifies additional interaction sites of UmuC with the beta clamp
    J Bacteriol (2009) 191, 5910-5920. PubMed  Europe PubMed DOI  PMC  EPMC
    19. 2004
  19. Fuchs,R.P., Fujii,S. and Wagner,J.
    Properties and functions of Escherichia coli: Pol IV and Pol V
    Adv Protein Chem (2004) 69, 229-264. PubMed  Europe PubMed DOI
  20. Paetzel,M. and Woodgate,R.
    UmuD and UmuD' proteins
    [ISSN:0-12-079610-4] (2004) 2, 1976-1981.  V
    21. 2003
  21. [YEAR:11-11-2003]Neher,S.B., Sauer,R.T. and Baker,T.A.
    Distinct peptide signals in the UmuD and UmuD' subunits of UmuD/D' mediate tethering and substrate processing by the ClpXP protease
    Proc Natl Acad Sci U S A (11-11-2003) 100, 13219-13224. PubMed  Europe PubMed DOI  PMC  EPMC
    22. 2002
  22. Gonzalez,M. and Woodgate,R.
    The "tale" of UmuD and its role in SOS mutagenesis
    Bioessays (2002) 24, 141-148. PubMed  Europe PubMed DOI
  23. [YEAR:22-1-2002]Sutton,M.D., Guzzo,A., Narumi,I., Costanzo,M., Altenbach,C., Ferentz,A.E., Hubbell,W.L. and Walker,G.C.
    A model for the structure of the Escherichia coli SOS-regulated UmuD2 protein
    DNA Repair (Amst) (22-1-2002) 1, 77-93. PubMed  Europe PubMed DOI
    24. 2001
  24. [YEAR:1-8-2001]Ferentz,A.E., Walker,G.C. and Wagner,G.
    Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C)
    EMBO J (1-8-2001) 20, 4287-4298. PubMed  Europe PubMed DOI  PMC  EPMC
  25. [YEAR:1-3-2001]Yasuda,T., Morimatsu,K., Kato,R., Usukura,J., Takahashi,M. and Ohmori,H.
    Physical interactions between DinI and RecA nucleoprotein filament for the regulation of SOS mutagenesis
    EMBO J (1-3-2001) 20, 1192-1202. PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2000
  26. [YEAR:2-10-2000]Gonzalez,M., Rasulova,F., Maurizi,M.R. and Woodgate,R.
    Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability
    EMBO J (2-10-2000) 19, 5251-5258. PubMed  Europe PubMed DOI  PMC  EPMC
  27. Sutton,M.D., Smith,B.T., Godoy,V.G. and Walker,G.C.
    The SOS response: recent insights into umuDC-dependent mutagenesis and DNA damage tolerance
    Annu Rev Genet (2000) 34, 479-497. PubMed  Europe PubMed DOI
    28. 1999
  28. [YEAR:5-2-1999]McDonald,J.P., Peat,T.S., Levine,A.S. and Woodgate,R.
    Intermolecular cleavage by UmuD-like enzymes: identification of residues required for cleavage and substrate specificity
    J Mol Biol (5-2-1999) 285, 2199-2209. PubMed  Europe PubMed DOI
  29. [YEAR:3-8-1999]Opperman,T., Murli,S., Smith,B.T. and Walker,G.C.
    A model for a umuDC-dependent prokaryotic DNA damage checkpoint
    Proc Natl Acad Sci U S A (3-8-1999) 96, 9218-9223. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Paetzel,M. and Strynadka,N.C.
    Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism
    Protein Sci (1999) 8, 2533-2536. PubMed  Europe PubMed DOI  PMC  EPMC  S
  31. [YEAR:5-11-1999]Reuven,N.B., Arad,G., Maor-Shoshani,A. and Livneh,Z.
    The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication
    J Biol Chem (5-11-1999) 274, 31763-31766. PubMed  Europe PubMed DOI
  32. [YEAR:8-6-1999]Smith,C.K., Baker,T.A. and Sauer,R.T.
    Lon and Clp family proteases and chaperones share homologous substrate-recognition domains
    Proc Natl Acad Sci U S A (8-6-1999) 96, 6678-6682. PubMed  Europe PubMed  PMC  EPMC
  33. [YEAR:3-8-1999]Tang,M., Shen,X., Frank,E.G., O'Donnell,M., Woodgate,R. and Goodman,M.F.
    UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V
    Proc Natl Acad Sci U S A (3-8-1999) 96, 8919-8924. PubMed  Europe PubMed  PMC  EPMC
    34. 1998
  34. [YEAR:20-2-1998]Konola,J.T., Guzzo,A., Gow,J.B., Walker,G.C. and Knight,K.L.
    Differential cleavage of LexA and UmuD mediated by recA pro67 mutants: Implications for common LexA and UmuD binding sites on RecA
    J Mol Biol (20-2-1998) 276, 405-415. PubMed  Europe PubMed DOI
  35. [YEAR:2-2-1998]Kulaeva,O.I., Koonin,E.V., Wootton,J.C., Levine,A.S. and Woodgate,R.
    Unusual insertion element polymorphisms in the promoter and terminator regions of the mucAB-like genes of R471a and R446b
    Mutat Res (2-2-1998) 397, 247-262. PubMed  Europe PubMed DOI
  36. [YEAR:2-10-1998]McDonald,J.P., Maury,E.E., Levine,A.S. and Woodgate,R.
    Regulation of UmuD cleavage: role of the amino-terminal tail
    J Mol Biol (2-10-1998) 282, 721-730. PubMed  Europe PubMed DOI
  37. [YEAR:17-2-1998]McDonald,J.P., Frank,E.G., Levine,A.S. and Woodgate,R.
    Intermolecular cleavage by UmuD-like mutagenesis proteins
    Proc Natl Acad Sci U S A (17-2-1998) 95, 1478-1483. PubMed  Europe PubMed DOI  PMC  EPMC
  38. [YEAR:18-8-1998]Tang,M., Bruck,I., Eritja,R., Turner,J., Frank,E.G., Woodgate,R., O'Donnell,M. and Goodman,M.F.
    Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein
    Proc Natl Acad Sci U S A (18-8-1998) 95, 9755-9760. PubMed  Europe PubMed  PMC  EPMC
    39. 1997
  39. Ferentz,A.E., Opperman,T., Walker,G.C. and Wagner,G.
    Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis
    Nat Struct Biol (1997) 4, 979-983. PubMed  Europe PubMed
    40. 1996
  40. [YEAR:3-5-1996]Bruck,I., Woodgate,R., McEntee,K. and Goodman,M.F.
    Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA
    J Biol Chem (3-5-1996) 271, 10767-10774. PubMed  Europe PubMed DOI
  41. Frank,E.G., Gonzalez,M., Ennis,D.G., Levine,A.S. and Woodgate,R.
    In vivo stability of the Umu mutagenesis proteins: a major role for RecA
    J Bacteriol (1996) 178, 3550-3556. PubMed  Europe PubMed  PMC  EPMC
  42. Peat,T.S., Frank,E.G., Woodgate,R. and Hendrickson,W.A.
    Production and crystallization of a selenomethionyl variant of UmuD', an Escherichia coli SOS response protein
    Proteins (1996) 25, 506-509. PubMed  Europe PubMed DOI  S
  43. [YEAR:15-12-1996]Peat,T.S., Frank,E.G., McDonald,J.P., Levine,A.S., Woodgate,R. and Hendrickson,W.A.
    The UmuD' protein filament and its potential role in damage induced mutagenesis
    Structure (15-12-1996) 4, 1401-1412. PubMed  Europe PubMed
  44. Peat,T.S., Frank,E.G., McDonald,J.P., Levine,A.S., Woodgate,R. and Hendrickson,W.A.
    Structure of the UmuD' protein and its regulation in response to DNA damage
    Nature (1996) 380, 727-730. PubMed  Europe PubMed DOI  S
    45. 1993
  45. [YEAR:1-9-1993]Frank,E.G., Hauser,J., Levine,A.S. and Woodgate,R.
    Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA protein
    Proc Natl Acad Sci U S A (1-9-1993) 90, 8169-8173. PubMed  Europe PubMed  PMC  EPMC
    46. 1991
  46. Nohmi,T., Hakura,A., Nakai,Y., Watanabe,M., Murayama,S.Y. and Sofuni,T.
    Salmonella typhimurium has two homologous but different umuDC operons: Cloning of a new umuDC-like operon (samAB) present in a 60-megadalton cryptic plasmid of S. typhimurium
    J Bacteriol (1991) 173, 1051-1063. PubMed  Europe PubMed  PMC  EPMC
  47. Woodgate,R., Levine,A.S., Koch,W.H., Cebula,T.A. and Eisenstadt,E.
    Induction and cleavage of Salmonella typhimurium UmuD protein
    Mol Gen Genet (1991) 229, 81-85. PubMed  Europe PubMed
    48. 1990
  48. Battista,J.R., Ohta,T., Nohmi,T., Sun,W. and Walker,G.C.
    Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis
    Proc Natl Acad Sci U S A (1990) 87, 7190-7194. PubMed  Europe PubMed  PMC  EPMC
    49. 1989
  49. Woodgate,R., Rajagopalan,M., Lu,C. and Echols,H.
    UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'
    Proc Natl Acad Sci U S A (1989) 86, 7301-7305. PubMed  Europe PubMed  PMC  EPMC
    50. 1988
  50. Burckhardt,S.E., Woodgate,R., Scheuermann,R.H. and Echols,H.
    UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA
    Proc Natl Acad Sci U S A (1988) 85, 1811-1815. PubMed  Europe PubMed DOI  PMC  EPMC
  51. Nohmi,T., Battista,J.R., Dodson,L.A. and Walker,G.C.
    RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation
    Proc Natl Acad Sci U S A (1988) 85, 1816-1820. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Shinagawa,H., Iwasaki,H., Kato,T. and Nakata,A.
    RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis
    Proc Natl Acad Sci U S A (1988) 85, 1806-1810. PubMed  Europe PubMed DOI  PMC  EPMC
    53. 1985
  53. Kitagawa,Y., Akaboshi,E., Shinagawa,H., Horii,T., Ogawa,H. and Kato,T.
    Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli
    Proc Natl Acad Sci U S A (1985) 82, 4336-4340. PubMed  Europe PubMed  PMC  EPMC
  54. Perry,K.L., Elledge,S.J., Mitchell,B.B., Marsh,L. and Walker,G.C.
    umuDC and mucAB operons whose products are required for UV light-and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology
    Proc Natl Acad Sci U S A (1985) 82, 4331-4335. PubMed  Europe PubMed  PMC  EPMC
    55. 1981
  55. Bagg,A., Kenyon,C.J. and Walker,G.C.
    Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli
    Proc Natl Acad Sci U S A (1981) 78, 5749-5753. PubMed  Europe PubMed  PMC  EPMC
    56. 1977
  56. [YEAR:14-11-1977]Kato,T. and Shinoura,Y.
    Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light
    Mol Gen Genet (14-11-1977) 156, 121-131. PubMed  Europe PubMed

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