Literature for peptidase S12.010: colibactin peptidase (Escherichia-type)

(Topics flags: S Structure, A Assay, T Target, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

2026
1. Ramos,M.A.A., Gutkin,S., David,M., Shabat,D. and Balskus,E.P.
   Chemiluminescent probes allow for the rapid identification of colibactin-producing bacteria
   bioRxiv (2026) PubMed  Europe PubMed DOI  PMC  EPMC
2024
2. Bayne,C., Boutard,M., Zaplana,T. and Tolonen,A.C.
   L-tryptophan and copper interactions linked to reduced colibactin genotoxicity in pks+ Escherichia coli
   mSystems (2024) , e0099224-e0099224. PubMed  Europe PubMed DOI
2019
3. Healy,A.R., Wernke,K.M., Kim,C.S., Lees,N.R., Crawford,J.M. and Herzon,S.B.
   Synthesis and reactivity of precolibactin 886
   Nat Chem (2019) 11, 890-898. PubMed  Europe PubMed DOI  PMC  EPMC
4. Hirayama,Y., Tsunematsu,Y., Yoshikawa,Y., Tamafune,R., Matsuzaki,N., Iwashita,Y., Ohnishi,I., Tanioka,F., Sato,M., Miyoshi,N., Mutoh,M., Ishikawa,H., Sugimura,H., Wakabayashi,K. and Watanabe,K.
   Activity-based probe for screening of high-colibactin producers from clinical samples
   Org Lett (2019) 21, 4490-4494. PubMed  Europe PubMed DOI  A
5. Volpe,M.R., Wilson,M.R., Brotherton,C.A., Winter,E.S., Johnson,S.E. and Balskus,E.P.
   In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe
   ACS Chem Biol (2019) 14, 1097-1101. PubMed  Europe PubMed DOI  A
2017
6. Healy,A.R. and Herzon,S.B.
   Molecular basis of gut microbiome-associated colorectal cancer: a synthetic perspective
   J Am Chem Soc (2017) 139, 14817-14824. PubMed  Europe PubMed DOI  K
7. Mousa,J.J., Newsome,R.C., Yang,Y., Jobin,C. and Bruner,S.D.
   ClbM is a versatile, cation-promiscuous MATE transporter found in the colibactin biosynthetic gene cluster
   Biochem Biophys Res Commun (2017) 482, 1233-1239. PubMed  Europe PubMed DOI
8. Trautman,E.P., Healy,A.R., Shine,E.E., Herzon,S.B. and Crawford,J.M.
   Domain-targeted metabolomics delineates the heterocycle assembly steps of colibactin biosynthesis
   J Am Chem Soc (2017) 139, 4195-4201. PubMed  Europe PubMed DOI
2016
9. Healy,A.R., Vizcaino,M.I., Crawford,J.M. and Herzon,S.B.
   Convergent and modular synthesis of candidate precolibactins. Structural revision of precolibactin A
   J Am Chem Soc (2016) 138, 5426-5432. PubMed  Europe PubMed DOI
2013
10. Brotherton,C.A. and Balskus,E.P.
    A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity
    J Am Chem Soc (2013) 135, 3359-3362. PubMed  Europe PubMed DOI
2012
11. Cougnoux,A., Gibold,L., Robin,F., Dubois,D., Pradel,N., Darfeuille-Michaud,A., Dalmasso,G., Delmas,J. and Bonnet,R.
    Analysis of structure-function relationships in the colibactin-maturating enzyme ClbP
    J Mol Biol (2012) 424, 203-214. PubMed  Europe PubMed DOI  T
2011
12. Dubois,D., Baron,O., Cougnoux,A., Delmas,J., Pradel,N., Boury,M., Bouchon,B., Bringer,M.A., Nougayrede,J.P., Oswald,E. and Bonnet,R.
    ClbP is a prototype of a peptidase subgroup involved in biosynthesis of nonribosomal peptides
    J Biol Chem (2011) 286, 35562-35570. PubMed  Europe PubMed DOI  S