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Literature for peptidase S08.019: lactocepin I

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: K Knockout, P Specificity, I Inhibitor, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Zawawi,N.F., Mubarik,N.R. and Ambarsari,L.<br>Partial Purification, Characterisation and Gene Detection of Protease by Lacticaseibacillus paracasei IN17 from Inasua<br>Trop Life Sci Res (2025) 36, 159-177. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Christensen,L.F., Hoie,M.H., Bang-Berthelsen,C.H., Marcatili,P. and Hansen,E.B.<br>Comparative Structure Analysis of the Multi-Domain, Cell Envelope Proteases of Lactic Acid Bacteria<br>Microorganisms (2023) 11 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2020
  3. Hansen,E.B. and Marcatili,P.<br>Modeled Structure of the Cell Envelope Proteinase of Lactococcus lactis<br>Front Bioeng Biotechnol (2020) 8, 613986-613986. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2017
  4. Okondo,M.C., Johnson,D.C., Sridharan,R., Go,E.B., Chui,A.J., Wang,M.S., Poplawski,S.E., Wu,W., Liu,Y., Lai,J.H., Sanford,D.G., Arciprete,M.O., Golub,T.R., Bachovchin,W.W. and Bachovchin,D.A.<br>DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis<br>Nat Chem Biol (2017) 13, 46-53. PubMed  Europe PubMed DOI  I
    5. 2016
  5. Guo,T., Ouyang,X., Xin,Y., Wang,Y., Zhang,S. and Kong,J.<br>Characterization of a new cell envelope proteinase PrtP from Lactobacillus rhamnosus CGMCC11055<br>J Agric Food Chem (2016) 64, 6985-6992. PubMed  Europe PubMed DOI  P
  6. Vukotic,G., Strahinic,I., Begovic,J., Lukic,J., Kojic,M. and Fira,D.<br>Survey on proteolytic activity and diversity of proteinase genes in mesophilic lactobacilli<br>Microbiology (2016) 85, 33-41. DOI
    7. 2015
  7. Borsting,M.W., Qvist,K.B., Brockmann,E., Vindelov,J., Pedersen,T.L., Vogensen,F.K. and Ardo,Y.<br>Classification of Lactococcus lactis cell envelope proteinase based on gene sequencing, peptides formed after hydrolysis of milk, and computer modeling<br>J Dairy Sci (2015) 98, 68-77. PubMed  Europe PubMed DOI
  8. Vukotic,G., Mirkovic,N., Jovcic,B., Miljkovic,M., Strahinic,I., Fira,D., Radulovic,Z. and Kojic,M.<br>Proteinase PrtP impairs lactococcin LcnB activity in Lactococcus lactis BGMN1-501: new insights into bacteriocin regulation<br>Front Microbiol (2015) 6, 92-92. PubMed  Europe PubMed DOI  PMC  EPMC  K
    9. 2013
  9. Griffiths,M.W. and Tellez,A.M.<br>Lactobacillus helveticus: the proteolytic system<br>Front Microbiol (2013) 4, 30-30. PubMed  Europe PubMed DOI  PMC  EPMC  V
  10. Hormannsperger,G., von Schillde,M.A. and Haller,D.<br>Lactocepin as a protective microbial structure in the context of IBD<br>Gut Microbes (2013) 4, 152-157. PubMed  Europe PubMed DOI
    11. 2012
  11. Broadbent,J.R. and Steele,J.L.<br>Lactocepin: the cell envelope-associated endopeptidase of lactococci<br>[ISSN:978-0-12-407742-3] (2012) 3, 3188-3195. DOI
  12. van Huynegem,K. and Steidler,L.<br>Clinical development of lactocepin: a novel bacterial biologic?<br>Expert Rev Clin Immunol (2012) 8, 597-599. PubMed  Europe PubMed DOI
  13. von Schillde,M.A., Hormannsperger,G., Weiher,M., Alpert,C.A., Hahne,H., Bauerl,C., van Huynegem,K., Steidler,L., Hrncir,T., Perez-Martinez,G., Kuster,B. and Haller,D.<br>Lactocepin secreted by lactobacillus exerts anti-inflammatory effects by selectively degrading proinflammatory chemokines<br>Cell Host Microbe (2012) 11, 387-396. PubMed  Europe PubMed DOI  U
    14. 2011
  14. Lozo,J., Strahinic,I., Dalgalarrondo,M., Chobert,J.M., Haertle,T. and Topisirovic,L.<br>Comparative analysis of beta-casein proteolysis by PrtP proteinase from Lactobacillus paracasei subsp. paracasei BGHN14, PrtR proteinase from Lactobacillus rhamnosus BGT10 and PrtH proteinase from Lactobacillus helveticus BGRA43<br>Int Dairy J (2011) 21, 863-868. DOI  P
    15. 2009
  15. Nikolic,M., Tolinacki,M., Fira,D., Golic,N. and Topisirovic,L.<br>Variation in specificity of the PrtP extracellular proteinases in Lactococcus lactis and Lactobacillus paracasei subsp. paracasei<br>Folia Microbiol (Praha) (2009) 54, 188-194. PubMed  Europe PubMed DOI
    16. 2007
  16. Habimana,O., Le Goff,C., Juillard,V., Bellon-Fontaine,M.N., Buist,G., Kulakauskas,S. and Briandet,R.<br>Positive role of cell wall anchored proteinase PrtP in adhesion of lactococci<br>BMC Microbiol (2007) 7, 36-36. PubMed  Europe PubMed DOI  PMC  EPMC
    17. 2006
  17. Broadbent,J.R., Rodriguez,B.T., Joseph,P., Smith,E.A. and Steele,J.L.<br>Conversion of Lactococcus lactis cell envelope proteinase specificity by partial allele exchange<br>J Appl Microbiol (2006) 100, 1307-1317. PubMed  Europe PubMed DOI
    18. 2004
  18. Reid,J.R. and Coolbear,T.<br>Lactocepin: the cell envelope-associated endopeptidase of lactococci<br>[ISSN:0-12-079610-4] (2004) 2, 1803-1808.  V
    19. 2001
  19. Christensson,C., Pillidge,C.J., Ward,L.J.H. and O'Toole,P.W.<br>Nucleotide sequence and characterization of the cell envelope proteinase plasmid in Lactococcus lactis subsp. cremoris HP<br>J Appl Microbiol (2001) 91, 334-343. PubMed  Europe PubMed DOI
    20. 2000
  20. Bruinenberg,P.G., de Vos,W.M. and Siezen,R.J.<br>Deletion of various carboxy-terminal domains of Lactococcus lactis SK11 proteinase: Effects on activity, specificity, and stability of the truncated enzyme<br>Appl Environ Microbiol (2000) 66, 2859-2865. PubMed  Europe PubMed DOI  PMC  EPMC
  21. Flambard,B. and Juillard,V.<br>The autoproteolysis of Lactococcus lactis lactocepin III affects its specificity towards beta-casein<br>Appl Environ Microbiol (2000) 66, 5134-5140. PubMed  Europe PubMed DOI  PMC  EPMC
    22. 1999
  22. Exterkate,F.A. and Alting,A.C.<br>Role of calcium in activity and stability of the Lactococcus lactis cell envelope proteinase<br>Appl Environ Microbiol (1999) 65, 1390-1396. PubMed  Europe PubMed  PMC  EPMC
  23. Reid,J.R. and Coolbear,T.<br>Specificity of Lactococcus lactis subsp. cremoris SK11 proteinase, lactocepin III, in low-water-activity, high-salt- concentration humectant systems and its stability compared with that of lactocepin I<br>Appl Environ Microbiol (1999) 65, 2947-2953. PubMed  Europe PubMed  PMC  EPMC
  24. Siezen,R.J.<br>Multi-domain, cell-envelope proteinases of lactic acid bacteria<br>Antonie Van Leeuwenhoek (1999) 76, 139-155. PubMed  Europe PubMed DOI
    25. 1998
  25. Kunji,E.R., Fang,G., Jeronimus-Stratingh,C.M., Bruins,A.P., Poolman,B. and Konings,W.N.<br>Reconstruction of the proteolytic pathway for use of beta-casein by Lactococcus lactis<br>Mol Microbiol (1998) 27, 1107-1118. PubMed  Europe PubMed DOI
  26. Reid,J.R. and Coolbear,T.<br>Altered specificity of lactococcal proteinase P(I) (lactocepin I) in humectant systems reflecting the water activity and salt content of cheddar cheese<br>Appl Environ Microbiol (1998) 64, 588-593. PubMed  Europe PubMed  PMC  EPMC
    27. 1995
  27. Juillard,V., Laan,H., Kunji,E.R., Jeronimus-Stratingh,C.M., Bruins,A.P. and Konings,W.N.<br>The extracellular PI-type proteinase of Lactococcus lactis hydrolyzes beta-casein into more than one hundred different oligopeptides<br>J Bacteriol (1995) 177, 3472-3478. PubMed  Europe PubMed  PMC  EPMC
  28. Reid,J.R., Coolbear,T., Moore,C.H., Harding,D.R. and Pritchard,G.G.<br>Involvement of enzyme-substrate charge interactions in the caseinolytic specificity of lactococcal cell envelope-associated proteinases<br>Appl Environ Microbiol (1995) 61, 3934-3939. PubMed  Europe PubMed  PMC  EPMC
    29. 1994
  29. Bruinenberg,P.G., Doesburg,P., Alting,A.C., Exterkate,F.A., de Vos,W.M. and Siezen,R.J.<br>Evidence for a large dispensable segment in the subtilisin-like catalytic domain of the Lactococcus lactis cell-envelope proteinase<br>Protein Eng (1994) 7, 991-996. PubMed  Europe PubMed
  30. Reid,J.R., Coolbear,T., Pillidge,C.J. and Pritchard,G.G.<br>Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains<br>Appl Environ Microbiol (1994) 60, 801-806. PubMed  Europe PubMed  PMC  EPMC
  31. Visser,S., Slangen,C.J., Robben,A.J., van Dongen,W.D., Heerma,W. and Haverkamp,J.<br>Action of a cell-envelope proteinase (CEPIII-type) from Lactococcus lactis subsp. cremoris AM1 on bovine kappa-casein<br>Appl Microbiol Biotechnol (1994) 41, 644-651. PubMed  Europe PubMed DOI
    32. 1993
  32. Exterkate,F.A., Alting,A.C. and Bruinenberg,P.G.<br>Diversity of cell envelope proteinase specificity among strains of Lactococcus lactis and its relationship to charge characteristics of the substrate-binding region<br>Appl Environ Microbiol (1993) 59, 3640-3647. PubMed  Europe PubMed  PMC  EPMC
  33. Exterkate,F.A. and Alting,A.C.<br>The conversion of the alpha(s1)-casein-(1-23)-fragment by the free and bound form of the cell-envelope proteinase of Lactococcus lactis subsp. cremoris under conditions prevailing in cheese<br>Syst Appl Microbiol (1993) 16, 1-8.  P
  34. Siezen,R.J., Bruinenberg,P.G., Vos,P., van Alen-Boerrigter,I., Nijhuis,M., Alting,A.C., Exterkate,F.A. and de Vos,W.M.<br>Engineering of the substrate-binding region of the subtilisin-like, cell-envelope proteinase of Lactococcus lactis<br>Protein Eng (1993) 6, 927-937. PubMed  Europe PubMed
  35. Tan,P.S., Poolman,B. and Konings,W.N.<br>Proteolytic enzymes of Lactococcus lactis<br>J Dairy Res (1993) 60, 269-286. PubMed  Europe PubMed
    36. 1992
  36. Coolbear,T., Reid,J.R. and Pritchard,G.G.<br>Stability and specificity of the cell wall-associated proteinase from Lactococcus lactis subsp. cremoris H2 released by treatment with lysozyme in the presence of calcium ions<br>Appl Environ Microbiol (1992) 58, 3263-3270. PubMed  Europe PubMed  PMC  EPMC
  37. Law,J., Vos,P., Hayes,F., Daly,C., de Vos,W.M. and Fitzgerald,G.<br>Cloning and partial sequencing of the proteinase gene complex from Lactococcus lactis subsp. lactis UC317<br>J Gen Microbiol (1992) 138, 709-718. PubMed  Europe PubMed
  38. Monnet,V., Ley,J.P. and Gonzalez,S.<br>Substrate specificity of the cell envelope-located proteinase of Lactococcus lactis subsp. lactis NCDO 763<br>Int J Biochem (1992) 24, 707-718. PubMed  Europe PubMed DOI
    39. 1991
  39. Kojic,M., Fira,D., Banina,A. and Topisirovic,L.<br>Characterization of the cell wall-bound proteinase of Lactobacillus casei HN14<br>Appl Environ Microbiol (1991) 57, 1753-1757. PubMed  Europe PubMed  PMC  EPMC
  40. Laan,H. and Konings,W.N.<br>Autoproteolysis of the extracellular serine proteinase of Lactococcus lactis subsp. cremoris Wg2<br>Appl Environ Microbiol (1991) 57, 2586-2590. PubMed  Europe PubMed  PMC  EPMC
    41. 1989
  41. Laan,H. and Konings,W.N.<br>Mechanism of proteinase release from Lactococcus lactis subsp. cremoris Wg2<br>Appl Environ Microbiol (1989) 55, 3101-3106. PubMed  Europe PubMed  PMC  EPMC
    42. 1988
  42. Kok,J., Hill,D., Haandrikman,A.J., de Reuver,M.J., Laan,H. and Venema,G.<br>Deletion analysis of the proteinase gene of Streptococcus cremoris Wg2<br>Appl Environ Microbiol (1988) 54, 239-244. PubMed  Europe PubMed  PMC  EPMC  K
  43. Laan,H., Smid,E.J., De Leij,L., Schwander,E. and Konings,W.N.<br>Monoclonal antibodies to the cell-wall-associated proteinase of Lactococcus lactis subsp. cremoris Wg2<br>Appl Environ Microbiol (1988) 54, 2250-2256. PubMed  Europe PubMed  PMC  EPMC
  44. Visser,S., Slangen,C.J., Exterkate,F.A. and de Veer,G.J.C.M.<br>Action of a cell wall proteinase (PI) from Streptococcus cremoris HP on bovine beta-casein<br>Appl Microbiol Biotechnol (1988) 29, 61-66. DOI
    45. 1987
  45. Exterkate,F.A. and deVeer,G.J.C.M.<br>Complexity of the native cell wall proteinase of Lactococcus lactis subsp. cremoris HP and purification of the enzyme<br>Syst Appl Microbiol (1987) 9, 183-191.
  46. Monnet,V., Lebars,D., Neviani,E. and Gripon,J.C.<br>Partial characterization and comparison of cell wall proteinases from 5 strains of Streptococcus lactis<br>Le Lait (1987) 67, 51-61.
    47. 1986
  47. Monnet,V., Le Bars,D. and Gripon,J.C.<br>Specificity of a cell wall proteinase from Streptococcus lactis NCDO763 towards bovine beta-casein<br>FEMS Microbiol Lett (1986) 36, 127-131.
  48. Visser,S., Exterkate,F.A., Slangen,C.J. and de Veer,G.J.<br>Comparative study of action of cell wall proteinases from various strains of Streptococcus cremoris on bovine alpha(s1)-, beta-, and kappa-casein<br>Appl Environ Microbiol (1986) 52, 1162-1166. PubMed  Europe PubMed  PMC  EPMC
    49. 1985
  49. Geis,A., Bockelmann,W. and Teuber,M.<br>Simultaneous extraction and purification of a cell wall-associated peptidase and beta-casein specific protease from Streptococcus cremoris AC1<br>Appl Microbiol Biotechnol (1985) 23, 79-84.
    50. 1984
  50. Hugenholtz,J., Exterkate,F. and Konings,W.N.<br>The proteolytic systems of Streptococcus cremoris: an immunological analysis<br>Appl Environ Microbiol (1984) 48, 1105-1110. PubMed  Europe PubMed  PMC  EPMC
    51. 1979
  51. Exterkate,F.A.<br>Accumulation of proteinase in the cell wall of Streptococcus cremoris strain AM1 and regulation of its production<br>Arch Microbiol (1979) 120, 247-254. DOI
    52. 1976
  52. Efstathiou,J.D. and McKay,L.L.<br>Plasmids in Streptococcus lactis: evidence that lactose metabolism and proteinase activity are plasmid linked<br>Appl Environ Microbiol (1976) 32, 38-44. PubMed  Europe PubMed  PMC  EPMC
    53. 1975
  53. McKay,L.L. and Baldwin,K.A.<br>Plasmid distribution and evidence for a proteinase plasmid in Streptococcus lactis C2-1<br>Appl Microbiol (1975) 29, 546-548. PubMed  Europe PubMed  PMC  EPMC
    54. 1971
  54. Westhoff,D.C., Cowman,R.A. and Speck,M.L.<br>Isolation and partial characterization of a particulate proteinase from a slow acid producing mutant of Streptococcus lactis<br>J Dairy Sci (1971) 54, 1253-1258. PubMed  Europe PubMed DOI

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