Literature for peptidase S06.010: EspC peptidase

(Topics flags: P Specificity. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Chen,Y., Gilliland,A., Liang,Q., Han,X., Yang,H., Chan,J., Levesque,D., Moon,K.M., Daneshgar,P., Boisvert,F.M., Foster,L., Zandberg,W.F., Bergstrom,K., Yu,H.B. and Vallance,B.A. Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus Gut Microbes (2025) 17, 2494717-2494717. PubMed Europe PubMed DOI PMC EPMC
Pilapitiya,A.U., Hor,L., Pan,J., Wijeyewickrema,L.C., Pike,R.N., Leyton,D.L., Paxman,J.J. and Heras,B. The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity Gut Microbes (2025) 17, 2483777-2483777. PubMed Europe PubMed DOI PMC EPMC

2016

Serapio-Palacios,A. and Navarro-Garcia,F. EspC, an autotransporter protein secreted by enteropathogenic Escherichia coli, causes apoptosis and necrosis through caspase and calpain activation, including direct procaspase-3 cleavage MBio (2016) 7 PubMed Europe PubMed DOI PMC EPMC

2015

Chua,E.G., Al-Hasani,K., Scanlon,M., Adler,B. and Sakellaris,H. Determinants of proteolysis and cell-binding for the Shigella flexneri cytotoxin, SigA Curr Microbiol (2015) 71, 613-617. PubMed Europe PubMed DOI
Guignot,J., Segura,A. and Tran Van Nhieu,G. The serine protease EspC from enteropathogenic Escherichia coli regulates pore formation and cytotoxicity mediated by the type III secretion system PLoS Pathog (2015) 11, e1005013-e1005013. PubMed Europe PubMed DOI

2014

Navarro-Garcia,F., Serapio-Palacios,A., Vidal,J.E., Salazar,M.I. and Tapia-Pastrana,G. EspC promotes epithelial cell detachment by enteropathogenic Escherichia coli via sequential cleavages of a cytoskeletal protein and then focal adhesion proteins Infect Immun (2014) 82, 2255-2265. PubMed Europe PubMed DOI P

2010

Navarro-Garcia,F., Sonnested,M. and Teter,K. Host-toxin interactions involving EspC and Pet, two serine protease autotransporters of the Enterobacteriaceae Toxins (Basel) (2010) 2, 1134-1147. PubMed Europe PubMed DOI PMC EPMC P

2009

Salinger,N., Kokona,B., Fairman,R. and Okeke,I.N. The plasmid-encoded regulator activates factors conferring lysozyme resistance on enteropathogenic Escherichia coli strains Appl Environ Microbiol (2009) 75, 275-280. PubMed Europe PubMed DOI PMC EPMC

2006

Drago-Serrano,M.E., Parra,S.G. and Manjarrez-Hernandez,H.A. EspC, an autotransporter protein secreted by enteropathogenic Escherichia coli (EPEC), displays protease activity on human hemoglobin FEMS Microbiol Lett (2006) 265, 35-40. PubMed Europe PubMed DOI

2004

Henderson,I.R., Navarro-Garcia,F., Desvaux,M., Fernandez,R.C. and Ala'Aldeen,D. Type V protein secretion pathway: the autotransporter story Microbiol Mol Biol Rev (2004) 68, 692-744. PubMed Europe PubMed DOI PMC EPMC
Navarro-Garcia,F., Canizalez-Roman,A., Sui,B.Q., Nataro,J.P. and Azamar,Y. The serine protease motif of EspC from enteropathogenic Escherichia coli produces epithelial damage by a mechanism different from that of Pet toxin from enteroaggregative E. coli Infect Immun (2004) 72, 3609-3621. PubMed Europe PubMed DOI PMC EPMC

2001

Mellies,J.L., Navarro-Garcia,F., Okeke,I., Frederickson,J., Nataro,J.P. and Kaper,J.B. espC pathogenicity island of enteropathogenic Escherichia coli encodes an enterotoxin Infect Immun (2001) 69, 315-324. PubMed Europe PubMed DOI PMC EPMC

2000

Al-Hasani,K., Henderson,I.R., Sakellaris,H., Rajakumar,K., Grant,T., Nataro,J.P., Robins-Browne,R. and Adler,B. The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation Infect Immun (2000) 68, 2457-2463. PubMed Europe PubMed DOI PMC EPMC

1997

Rajakumar,K., Sasakawa,C. and Adler,B. Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins Infect Immun (1997) 65, 4606-4614. PubMed Europe PubMed PMC EPMC

1996

Stein,M., Kenny,B., Stein,M.A. and Finlay,B.B. Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins J Bacteriol (1996) 178, 6546-6554. PubMed Europe PubMed PMC EPMC