Literature for subfamily S1A unassigned peptidases

Summary Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: P Specificity, I Inhibitor, K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Charoensapsri,W., Jearaphunt,M., Imjongjirak,C. and Amparyup,P. Clip-domain serine proteinases and their homologs: Role in crustacean immunity Dev Comp Immunol (2025) 172, 105465-105465. PubMed Europe PubMed DOI
Chen,Y., Zhao,H., Cao,S., Xie,H., Huang,J., Chen,X. and Cui,Z. Molecular characterization of large yellow croaker (Larimichthys crocea) coagulation factor VII-like and its function on macrophage proliferation and polarization Fish Shellfish Immunol (2025) 158, 110174-110174. PubMed Europe PubMed DOI
Gong,B., Zhang,S., Zheng,Y., Wang,Y., Teng,Y., Ni,K., Chen,M., Chen,J. and Chen,X. Molecular characterization and functional analysis of Granzyme B in large yellow croaker (Larimichthys crocea) Fish Shellfish Immunol (2025) 168, 110969-110969. PubMed Europe PubMed DOI
Guo,X., Zhang,X.Z., Zhang,Y., Zhang,R., Long,S.R., Dan Liu,R., Cui,J. and Wang,Z.Q. Characterization of a novel invasive virulence of chymotrypsin-like elastase family member 2A from Trichinella spiralis Acta Trop (2025) 270, 107803-107803. PubMed Europe PubMed DOI
Romanazzi,M., Filardi,E.T.M., Pires,G.M.M., Cerveja,M.F., Melo-Dos-Santos,G., Oliveira,I.S., Ferreira,I.G., Cerni,F.A., Santos-Filho,N.A., Monteiro,W.M., Almeida,J.R., Vaiyapuri,S. and Pucca,M.B. The Versatility of Serine Proteases from Brazilian Bothrops Venom: Their Roles in Snakebites and Drug Discovery Biomolecules (2025) 15 PubMed Europe PubMed DOI PMC EPMC V

2024

Asad,M., Liao,J., Chen,J., Munir,F., Pang,S., Abbas,A.N. and Yang,G. Exploring the role of the ovary-serine protease gene in the female fertility of the diamondback moth using CRISPR/Cas9 Pest Manag Sci (2024) PubMed Europe PubMed DOI
Cao,Y., Zhang,J., Wang,D., Zheng,Y., Cheng,J., Geng,M., Li,K., Yang,J. and Wei,X. Granzyme B secreted by T cells is involved in anti-bacterial immune response of tilapia Fish Shellfish Immunol (2024) 153, 109865-109865. PubMed Europe PubMed DOI
Li,T., Li,W., Guo,Y., Han,L., Zhang,W., Liu,R. and Feng,H. An optimization by response surface methodology for the enhanced production of rMBSP from Pichia pastoris and study of its application Prep Biochem Biotechnol (2024) , 1-9. PubMed Europe PubMed DOI
Liu,X.H., Liu,X.T., Wu,Y., Li,S.A., Ren,K.D., Cheng,M., Huang,B., Yang,Y. and Liu,P.P. Broadening Horizons: Exploring the Cathepsin Family as Therapeutic Targets for Alzheimer's Disease Aging Dis (2024) PubMed Europe PubMed DOI V
Ma,N., Lv,H., Boamah,S., Zhang,S. and Xu,B. Purification and Identification of the Nematicidal Activity of S1 Family Trypsin-Like Serine Protease (PRA1) from Trichoderma longibrachiatum T6 Through Prokaryotic Expression and Biological Function Assays Genes (Basel) (2024) 15 PubMed Europe PubMed DOI PMC EPMC
Rani,A., Pandey,D.M. and Pandey,J.P. Biomolecular characterization of Antheraea mylitta cocoonase: A secreted protease Anal Biochem (2024) 686, 115408-115408. PubMed Europe PubMed DOI
Saab,S.A., Zhang,X., Zeineddine,S., Morejon,B., Michel,K. and Osta,M.A. Insight into the structural hierarchy of the protease cascade that regulates the mosquito melanization response Microbes Infect (2024) 26, 105245-105245. PubMed Europe PubMed DOI
Song,T., Diao,X., Cheng,J., Man,Y., Chen,B., Zhang,H. and Wu,W. Recombinant Plasminogen Activator of the Sandworm (Perinereis aibuhitensis) Expression in Escherichia coli Bioengineering (Basel) (2024) 11 PubMed Europe PubMed DOI PMC EPMC
Wakuda,M., Sakamoto,T., Tanaka,A., Sugimura,S., Higashiura,Y., Nakazato,T., Bono,H. and Tabunoki,H. High expression of serine protease, Brachyurin in the posterior midgut of black soldier fly (Hermetia illucens) during horse dropping processing BMC Res Notes (2024) 17, 182-182. PubMed Europe PubMed DOI PMC EPMC

2023

Li,W., Dou,W. and Wang,J.J. BdcSP10 is a prophenoloxidase-activating protease in Bactrocera dorsalis Dev Comp Immunol (2023) 138, 104558-104558. PubMed Europe PubMed DOI K
Tsutsui,S., Yoshimura,A., Iwakuma,Y. and Nakamura,O. Discovery of Teleost Plasma Kallikrein/Coagulation Factor XI-Like Gene from Channel Catfish (Ictalurus punctatus) and the Evidence that the Protein Encoded by it Acts as a Lectin J Mol Evol (2023) 91, 536-551. PubMed Europe PubMed DOI
Vilca-Quispe,A., Alvarez-Risco,A., Gomes Heleno,M.A., Ponce-Fuentes,E.A., Vera-Gonzales,C., Zegarra-Aragon,H.F.E., Aquino-Puma,J.L., Talavera-Nunez,M.E., Del-Aguila-Arcentales,S., Yanez,J.A. and Ponce-Soto,L.A. Biochemical and hemostatic description of a thrombin-like enzyme TLBro from Bothrops roedingeri snake venom Front Chem (2023) 11, 1217329-1217329. PubMed Europe PubMed DOI PMC EPMC
Wei,P., Yang,W., Wang,W., Li,Y., Yan,X., Wu,W., Wang,S., Sun,J., Wang,L. and Song,L. A MASP-like functions as PRR to regulate the mRNA expressions of inflammatory factors in the Pacific oyster Crassostrea gigas Fish Shellfish Immunol (2023) 138, 108829-108829. PubMed Europe PubMed DOI

2022

Kim,E.Y., Jung,J.K., Kim,I.H. and Kim,Y. Chymotrypsin is a molecular target of insect resistance of three corn varieties against the Asian corn borer, Ostrinia furnacalis PLoS ONE (2022) 17, e0266751-e0266751. PubMed Europe PubMed DOI
Liang,H., Zhang,M., Shen,C., He,J., Lu,J. and Guo,Z. Cloning and functional analysis of a trypsin-like serine protease from Pinctada fucata martensii Fish Shellfish Immunol (2022) 126, 327-335. PubMed Europe PubMed DOI
Sakakura,M., Takata,Y., Kimura,C., Matsuda,S., Takamura,T. and Nagaoka,S. Limited proteolysis by a prostatic endopeptidase, the sperm-activating factor initiatorin, regulates the activation of pro-carboxypeptidase B in the seminal fluid of the silkworm, Bombyx mori Insect Biochem Mol Biol (2022) 148, 103819-103819. PubMed Europe PubMed DOI
Verma,R.K. and Teper,D. Immune recognition of the secreted serine protease ChpG restricts the host range of Clavibacter michiganensis from eggplant varieties Mol Plant Pathol (2022) 23, 933-946. PubMed Europe PubMed DOI PMC EPMC
Xiao,K., Zhang,S. and Li,C. The complement system and complement-like factors in sea cucumber Dev Comp Immunol (2022) 136, 104511-104511. PubMed Europe PubMed DOI V
You,Y., Sun,X., Ma,M., He,J., Li,L., Porto,F.W. and Lin,S. Trypsin is a coordinate regulator of N and P nutrients in marine phytoplankton Nat Commun (2022) 13, 4022-4022. PubMed Europe PubMed DOI PMC EPMC

2021

Sun,J., Wang,L., Yang,W., Li,Y., Jin,Y., Wang,L. and Song,L. A novel C-type lectin activates the complement cascade in the primitive oyster Crassostrea gigas J Biol Chem (2021) 297, 101352-101352. PubMed Europe PubMed DOI PMC EPMC

2020

Cao,X., Lu,Y., Li,J., Xia,X., Gao,Q., Gu,W., Wang,W. and Meng,Q. An ShK-domain serine protease of Eriocheir sinensis regulates the PO activity to resist Spiroplasma eriocheiris infection Fish Shellfish Immunol (2020) PubMed Europe PubMed DOI K
de Almeida Barros,R., Merino-Cabrera,Y., Vital,C.E., da Silva Junior,N.R., de Oliveira,C.N., Lessa Barbosa,S., Marques Goncalves Assis,J.V., Ramos,H.J. and de Almeida Oliveira,M.G. Small peptides inhibit gut trypsin-like proteases and impair Anticarsia gemmatalis (Lepidoptera: Noctuidae) survival and development Pest Manag Sci (2020) PubMed Europe PubMed DOI I
Li,X., Liu,X., Pang,X., Yin,Y., Yu,H., Yuan,Y. and Li,B. Transcriptomic analysis reveals hub genes and subnetworks related to ROS metabolism in Hylocereus undatus through novel superoxide scavenger trypsin treatment during storage BMC Genomics (2020) 21, 437-437. PubMed Europe PubMed DOI PMC EPMC
Shi,J.Y., Pan,H.Y., Liu,K., Pan,M. and Si,G.J. Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability Arch Biochem Biophys (2020) 690, 108460-108460. PubMed Europe PubMed DOI
Xu,D., Tang,B., Wang,Y., Zhang,L., Qu,Z., Shi,W., Wang,X., Sun,Q., Sun,S. and Liu,M. The immune protection induced by a serine protease from the Trichinella spiralis adult administered as DNA and protein vaccine Acta Trop (2020) 211, 105622-105622. PubMed Europe PubMed DOI
Yang,F., Guo,K.X., Yang,D.Q., Liu,R.D., Long,S.R., Zhang,X., Jiang,P., Cui,J. and Wang,Z.Q. Functional analysis of Trichinella spiralis serine protease 1.2 by siRNA mediated RNA interference Trop Biomed (2020) 37, 458-470. PubMed Europe PubMed
Zhang,X., Li,M., El Moussawi,L., Saab,S., Zhang,S., Osta,M.A. and Michel,K. CLIPB10 is a Terminal Protease in the Regulatory Network That Controls Melanization in the African Malaria Mosquito Anopheles gambiae Front Cell Infect Microbiol (2020) 10, 585986-585986. PubMed Europe PubMed DOI PMC EPMC K
Zhang,Y., Zeng,J., Song,Y.Y., Long,S.R., Liu,R.D., Jiang,P., Zhang,X., Cui,J. and Wang,Z.Q. Vaccination of Mice with a Novel Trypsin from Trichinella spiralis Elicits the Immune Protection against Larval Challenge Vaccines (Basel) (2020) 8 PubMed Europe PubMed DOI

2019

Gao,L., Wang,L., Yang,X., Wang,Y., Liu,Z., Xu,B. and Guo,X. Role of a serine protease gene (AccSp1) from Apis cerana cerana in abiotic stress responses and innate immunity Cell Stress Chaperones (2019) 24, 29-43. PubMed Europe PubMed DOI
Saikhedkar,N.S., Joshi,R.S., Yadav,A.K., Seal,S., Fernandes,M. and Giri,A.P. Phyto-inspired cyclic peptides derived from plant Pin-II type protease inhibitor reactive center loops for crop protection from insect pests Biochim Biophys Acta Gen Subj (2019) 1863, 1254-1262. PubMed Europe PubMed DOI
Salah Eldein,E., Abdalla,M., Eltayb,W.A., El-Arabey,A.A., Ganash,M., Alshammari,F.D., Barreto,G. and Ashraf,G.M. Molecular cloning, expression, purification, and functional characterization of SP-22 gene from Bombyx mori J Cell Biochem (2019) 120, 15594-15603. PubMed Europe PubMed DOI
Wu,J.M., Zheng,R.E., Zhang,R.J., Ji,J.L., Yu,X.P. and Xu,Y.P. A Clip domain serine protease involved in egg production in Nilaparvata lugens: expression patterns and RNA interference Insects (2019) 10 PubMed Europe PubMed DOI
Ye,L., Wang,Y., Long,L., Luo,H., Shen,Q., Broughton,S., Wu,D., Shu,X., Dai,F., Li,C. and Zhang,G. A trypsin family protein gene controls tillering and leaf shape in barley Plant Physiol (2019) 181, 701-713. PubMed Europe PubMed DOI

2018

Cherifi,F., Saoud,S. and Laraba-Djebari,F. Molecular modeling, biochemical characterization, and pharmacological properties of Cc3 -SPase: a platelet-aggregating thrombin-like enzyme purified from Cerastes cerastes venom J Biochem Mol Toxicol (2018) , e22165-e22165. PubMed Europe PubMed DOI
Costa,C.R.C., Belchor,M.N., Rodrigues,C.F.B., Toyama,D.O., de Oliveira,M.A., Novaes,D.P. and Toyama,M.H. Edema induced by a Crotalus durissus terrificus venom serine protease (Cdtsp 2) involves the PAR pathway and PKC and PLC activation Int J Mol Sci (2018) 19 PubMed Europe PubMed DOI
Fu,Z., Thorpe,M., Akula,S., Chahal,G. and Hellman,L.T. Extended cleavage specificity of human neutrophil elastase, human proteinase 3, and their distant ortholog clawed frog PR3-three elastases with similar primary but different extended specificities and stability Front Immunol (2018) 9, 2387-2387. PubMed Europe PubMed DOI PMC EPMC P
He,Y., Wang,Y., Hu,Y. and Jiang,H. Manduca sexta hemolymph protease-2 (HP2) activated by HP14 generates prophenoloxidase-activating protease-2 (PAP2) in wandering larvae and pupae Insect Biochem Mol Biol (2018) 101, 57-65. PubMed Europe PubMed DOI
Lange,J., Demir,F., Huesgen,P.F., Baumann,U., von Elert,E. and Pichlo,C. Heterologous expression and characterization of a novel serine protease from Daphnia magna: a possible role in susceptibility to toxic cyanobacteria Aquat Toxicol (2018) 205, 140-147. PubMed Europe PubMed DOI
Langenegger,N., Koua,D., Schurch,S., Heller,M., Nentwig,W. and Kuhn-Nentwig,L. Identification of a precursor processing protease from the spider Cupiennius salei essential for venom neurotoxin maturation J Biol Chem (2018) 293, 2079-2090. PubMed Europe PubMed DOI
Leontovyc,A., Ulrychova,L., O'Donoghue,A.J., Vondrasek,J., Maresova,L., Hubalek,M., Fajtova,P., Chanova,M., Jiang,Z., Craik,C.S., Caffrey,C.R., Mares,M., Dvorak,J. and Horn,M. SmSP2: a serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties PLoS Negl Trop Dis (2018) 12, e0006446-e0006446. PubMed Europe PubMed DOI
Sun,G.G., Song,Y.Y., Jiang,P., Ren,H.N., Yan,S.W., Han,Y., Liu,R.D., Zhang,X., Wang,Z.Q. and Cui,J. Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool PLoS Negl Trop Dis (2018) 12, e0006485-e0006485. PubMed Europe PubMed DOI
Sun,G.G., Ren,H.N., Liu,R.D., Song,Y.Y., Qi,X., Hu,C.X., Yang,F., Jiang,P., Zhang,X., Wang,Z.Q. and Cui,J. Molecular characterization of a putative serine protease from Trichinella spiralis and its elicited immune protection Vet Res (2018) 49, 59-59. PubMed Europe PubMed DOI PMC EPMC
Yang,J., Vrettou,C., Connelley,T. and Morrison,W.I. Identification and annotation of bovine granzyme genes reveals a novel granzyme encoded within the trypsin-like locus Immunogenetics (2018) 70, 585-597. PubMed Europe PubMed DOI
Zhou,T., Wang,X., Yan,J. and Li,Y. Gene analysis and structure prediction for the cold-adaption mechanism of trypsin from the krill Euphausia superba (Dana, 1852) J Sci Food Agric (2018) 98, 3049-3056. PubMed Europe PubMed DOI

2017

Albaum,D., Broehan,G., Muthukrishnan,S. and Merzendorfer,H. Functional analysis of TcCTLP-5C2, a chymotrypsin-like serine protease needed for molting in Tribolium castaneum Insect Biochem Mol Biol (2017) 86, 20-28. PubMed Europe PubMed DOI
Cao,X., Gulati,M. and Jiang,H. Serine protease-related proteins in the malaria mosquito, Anopheles gambiae Insect Biochem Mol Biol (2017) 88, 48-62. PubMed Europe PubMed DOI
He,Y., Wang,Y., Yang,F. and Jiang,H. Manduca sexta hemolymph protease-1, activated by an unconventional non-proteolytic mechanism, mediates immune responses Insect Biochem Mol Biol (2017) 84, 23-31. PubMed Europe PubMed DOI
Hu,J.J., Chen,Y.L., Duan,X.K., Jin,T.C., Li,Y., Zhang,L.J., Liu,G.M. and Cao,M.J. Involvement of clip-domain serine protease in the anti-Vibrio immune response of abalone (Haliotis discus hannai). Molecular cloning, characterization and functional analysis Fish Shellfish Immunol (2017) 72, 210-219. PubMed Europe PubMed DOI
Liu,M., Liu,Y., Hui,M., Song,C. and Cui,Z. Polymorphisms of clip domain serine proteinase and serine proteinase homolog in the swimming crab Portunus trituberculatus and their association with Vibrio alginolyticus Chin J Oceanol Limnol (2017) 35, 235-243. DOI
Shukla,E., Agrawal,S.B. and Gaikwad,S.M. Conformational and functional transitions and in silico analysis of a serine protease from Conidiobolus brefeldianus (MTCC 5185) Int J Biol Macromol (2017) 98, 387-397. PubMed Europe PubMed DOI
Sun,Y., Wang,Y., Liu,W., Zhou,J.L., Zeng,J., Wang,X.H., Jiang,Y.R., Li,D.H. and Qin,L. Upregulation of a trypsin-like serine protease gene in Antheraea pernyi (Lepidoptera: Saturniidae) strains exposed to different pathogens J Econ Entomol (2017) 110, 941-948. PubMed Europe PubMed DOI
Yeon,S.J., Shim,K.H., Hong,J.S. and Shin,H.S. Identification of a new serine protease from polychaeta, Marphysa sanguinea, for its thrombolytic and anticoagulant activity Korean J Chem Eng (2017) 34, 781-786. DOI

2016

de Oliveira,F., de Sousa,B.B., Mamede,C.C., de Morais,N.C., de Queiroz,M.R., da Cunha Pereira,D.F., Matias,M.S. and Homi Brandeburgo,M.I. Biochemical and functional characterization of BmooSP, a new serine protease from Bothrops moojeni snake venom Toxicon (2016) 111, 130-138. PubMed Europe PubMed DOI
Murray,A.S., Varela,F.A. and List,K. Type II transmembrane serine proteases as potential targets for cancer therapy Biol Chem (2016) 397, 815-826. PubMed Europe PubMed DOI
Poppel,A.K., Kahl,M., Baumann,A., Wiesner,J., Gokcen,A., Beckert,A., Preissner,K.T., Vilcinskas,A. and Franta,Z. A Jonah-like chymotrypsin from the therapeutic maggot Lucilia sericata plays a role in wound debridement and coagulation Insect Biochem Mol Biol (2016) 70, 138-147. PubMed Europe PubMed DOI
Wang,D., Zhang,Y., Dong,Z., Guo,P., Ma,S., Guo,K., Xia,Q. and Zhao,P. Serine protease P-IIc is responsible for the digestion of yolk proteins at the late stage of silkworm embryogenesis Insect Biochem Mol Biol (2016) 74, 42-49. PubMed Europe PubMed DOI
Yang,F., Wang,Y., He,Y. and Jiang,H. In search of a function of Manduca sexta hemolymph protease-1 in the innate immune system Insect Biochem Mol Biol (2016) 76, 1-10. PubMed Europe PubMed DOI

2015

Bibo-Verdugo,B., Rojo-Arreola,L., Navarrete-Del-Toro,M.A. and Garcia-Carreno,F. A chymotrypsin from the digestive tract of California spiny lobster, Panulirus interruptus: purification and biochemical characterization Mar Biotechnol (NY) (2015) 17, 416-427. PubMed Europe PubMed DOI
Boldrini-Franca,J., Rodrigues,R.S., Santos-Silva,L.K., de Souza,D.L., Gomes,M.S., Cologna,C.T., de Pauw,E., Quinton,L., Henrique-Silva,F., de Melo Rodrigues,V. and Arantes,E.C. Expression of a new serine protease from Crotalus durissus collilineatus venom in Pichia pastoris and functional comparison with the native enzyme Appl Microbiol Biotechnol (2015) 99, 9971-9986. PubMed Europe PubMed DOI
Borges-Veloso,A., Saboia-Vahia,L., Dias-Lopes,G., Domont,G.B., Britto,C., Cuervo,P. and De Jesus,J.B. In-depth characterization of trypsin-like serine peptidases in the midgut of the sugar fed Culex quinquefasciatus Parasit Vectors (2015) 8, 373-373. PubMed Europe PubMed DOI PMC EPMC
Chernyshenko,V.O. Limited proteolysis of fibrinogen by fibrinogenase from Echis multisquamatis venom Protein J (2015) 34, 130-134. PubMed Europe PubMed DOI
Villas Boas,I.M., Pidde-Queiroz,G., Magnoli,F.C., Goncalves-de-Andrade,R.M., Van Den Berg,C.W. and Tambourgi,D.V. A serine protease isolated from the bristles of the amazonic caterpillar, Premolis semirufa, is a potent complement system activator PLoS ONE (2015) 10, e0118615-e0118615. PubMed Europe PubMed DOI PMC EPMC

2014

Arockiaraj,J., Palanisamy,R., Kumaresan,V., Bhatt,P., Chaurasia,M.K., Kasi,M., Pasupuleti,M. and Gnanam,A.J. Striped murrel S1 family serine protease: immune characterization, antibacterial property and enzyme activities Biologia (2014) 69, 1065-1078. DOI
Chernyshenko,V., Platonova,T., Makogonenko,Y., Rebriev,A., Mikhalovska,L., Chernyshenko,T. and Komisarenko,S. Fibrin(ogen)olytic and platelet modulating activity of a novel protease from the Echis multisquamatis snake venom Biochimie (2014) 105, 76-83. PubMed Europe PubMed DOI
Fu,G.H., Wan,Z.Y., Xia,J.H., Liu,F., Liu,X.J. and Yue,G.H. The MCP-8 gene and its possible association with resistance to Streptococcus agalactiae in tilapia Fish Shellfish Immunol (2014) 40, 331-336. PubMed Europe PubMed DOI
Horn,M., Fajtova,P., Rojo Arreola,L., Ulrychova,L., Bartosova-Sojkova,P., Franta,Z., Protasio,A.V., Opavsky,D., Vondrasek,J., McKerrow,J.H., Mares,M., Caffrey,C.R. and Dvorak,J. Trypsin- and chymotrypsin-like serine proteases in Schistosoma mansoni - 'the undiscovered country' PLoS Negl Trop Dis (2014) 8, e2766-e2766. PubMed Europe PubMed DOI PMC EPMC
Ju,J.Y., Chu,J.X. and Zhao,C.L. Cloning and activity analysis of a new protease from Arenicola cristata Adv Mater Res (2014) 998-999, 206-209. DOI
Kurtovic,T., Brgles,M., Leonardi,A., Lang Balija,M., Sajevic,T., Krizaj,I., Allmaier,G., Marchetti-Deschmann,M. and Halassy,B. VaSP1, catalytically active serine proteinase from Vipera ammodytes ammodytes venom with unconventional active site triad Toxicon (2014) 77, 93-104. PubMed Europe PubMed DOI
Mizuno,T., Nanko,A., Maehara,Y., Shinoda,S. and Miyoshi,S. A novel extracellular protease of Vibrio mimicus that mediates maturation of an endogenous hemolysin Microbiol Immunol (2014) 58, 503-512. PubMed Europe PubMed DOI
Pichu,S., Ribeiro,J.M., Mather,T.N. and Francischetti,I.M. Purification of a serine protease and evidence for a protein C activator from the saliva of the tick, Ixodes scapularis Toxicon (2014) 77, 32-39. PubMed Europe PubMed DOI
van der Plas,M.J., Andersen,A.S., Nazir,S., van Tilburg,N.H., Oestergaard,P.R., Krogfelt,K.A., van Dissel,J.T., Hensbergen,P.J., Bertina,R.M. and Nibbering,P.H. A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis PLoS ONE (2014) 9, e92096-e92096. PubMed Europe PubMed DOI PMC EPMC
Wang,S., Xu,X., Gao,S., Zhu,S., Rong,R. and Li,B. Purification and partial characterization of a novel fibrinogenase from the venom of Deinagkistrodon acutus: inhibition of platelet aggregation Protein Expr Purif (2014) 99, 99-105. PubMed Europe PubMed DOI
Yang,Q.Z., Yang,Z.J., Zhang,Y., Li,X.L. and Zhang,W. Molecular characteristic and expression analysis of collagenolytic serine protease from the Chinese mitten crab Eriocheir sinensis with defense response to Vibrio anguillarum challenge Genet Mol Res (2014) 13, 3885-3894. PubMed Europe PubMed DOI
Zhao,C. and Ju,J. Molecular cloning, expression, and anti-tumor activity of a novel serine protease from Arenicola cristata Acta Biochim Biophys Sin (Shanghai) (2014) 46, 450-459. PubMed Europe PubMed DOI
Zhao,C.L., Yu,W.J. and Ju,J.Y. Anti-tumor effects of a newly cloned serine protease from the marine annelid, Arenicola cristata Adv Mater Res (2014) 998-999, 183-186. DOI E
Zhao,C.L., Y,W.J. and Ju,J.Y. Cloning and expression of a novel protease with fibrinolytic activity from Arenicola cristata Adv Mater Res (2014) 998-999, 210-213. DOI

2013

Amparyup,P., Promrungreang,K., Charoensapsri,W., Sutthangkul,J. and Tassanakajon,A. A serine proteinase PmClipSP2 contributes to prophenoloxidase system and plays a protective role in shrimp defense by scavenging lipopolysaccharide Dev Comp Immunol (2013) 41, 597-607. PubMed Europe PubMed DOI
Bi,Q., Chu,J., Feng,Y., Jiang,Z., Han,B. and Liu,W. Purification and characterization of a new serine protease with fibrinolytic activity from the marine invertebrate, Urechis unicinctus Appl Biochem Biotechnol (2013) 170, 525-540. PubMed Europe PubMed DOI
Bi,Q., Han,B., Liu,W., Feng,Y. and Jiang,Z. UFEIII, a fibrinolytic protease from the marine invertebrate, Urechis unicinctus Biotechnol Lett (2013) 35, 1115-1120. PubMed Europe PubMed DOI
Bi,Q., Han,B., Feng,Y., Jiang,Z., Yang,Y. and Liu,W. Antithrombotic effects of a newly purified fibrinolytic protease from Urechis unicinctus Thromb Res (2013) 132, e135-e144. PubMed Europe PubMed DOI
Fang,D.A., Huang,X.M., Zhang,Z.Q., Xu,D.P., Zhou,Y.F., Zhang,M.Y., Liu,K., Duan,J.R. and Shi,W.G. Molecular cloning and expression analysis of chymotrypsin-like serine protease from the redclaw crayfish (Cherax quadricarinatus): A possible role in the junior and adult innate immune systems Fish Shellfish Immunol (2013) 34, 1546-1552. PubMed Europe PubMed DOI
Guo,C., Liu,S., Zheng,T. and Sun,M.-Z. A novel thrombin-like gene obtained from Chinese Gloydius shedaoensis shedaoensis J Anim Plant Sci (2013) 23, 1398-1406.
Kumar,R.V., Yariswamy,M., Joshi,V., Dharmappa,K.K., Venkatesha,S.H., Sharath,B.K. and Vishwanath,B.S. Malabarase, a serine protease with anticoagulant activity from Trimeresurus malabaricus venom Comp Biochem Physiol B Biochem Mol Biol (2013) 164, 111-116. PubMed Europe PubMed DOI
Li,X., Yao,J.P., Pan,A.H., Liu,W., Hu,X.C., Wu,Z.D. and Zhou,X.W. An antigenic recombinant serine protease from Trichinella spiralis induces protective immunity in BALB/c mice Parasitol Res (2013) 112, 3229-3238. PubMed Europe PubMed DOI E
Menaldo,D.L., Bernardes,C.P., Pereira,J.C., Silveira,D.S.C., Mamede,C.C.N., Stanziola,L., Oliveira,F.D., Pereira-Crott,L.S., Faccioli,L.H. and Sampaio,S.V. Effects of two serine proteases from Bothrops pirajai snake venom on the complement system and the inflammatory response Int Immunopharmacol (2013) 15, 764-771. PubMed Europe PubMed DOI
Mukherjee,A.K. and Mackessy,S.P. Biochemical and pharmacological properties of a new thrombin-like serine protease (russelobin) from the venom of Russell's viper (Daboia russelii russelii) and assessment of its therapeutic potential Biochim Biophys Acta (2013) 1830, 3476-3488. PubMed Europe PubMed DOI
Patino,A.C., Pereanez,J.A., Gutierrez,J.M. and Rucavado,A. Biochemical and biological characterization of two serine proteinases from Colombian Crotalus durissus cumanensis snake venom Toxicon (2013) 63, 32-43. PubMed Europe PubMed DOI
Song,C., Cui,Z., Liu,Y., Li,Q., Li,X., Shi,G. and Wang,C. Characterization and functional analysis of serine proteinase and serine proteinase homologue from the swimming crab Portunus trituberculatus Fish Shellfish Immunol (2013) 35, 231-239. PubMed Europe PubMed DOI
Vivas-Ruiz,D.E., Sandoval,G.A., Mendoza,J., Inga,R.R., Gontijo,S., Richardson,M., Eble,J.A., Yarleque,A. and Sanchez,E.F. Coagulant thrombin-like enzyme (barnettobin) from Bothrops barnetti venom: Molecular sequence analysis of its cDNA and biochemical properties Biochimie (2013) 95, 1476-1486. PubMed Europe PubMed DOI
Wang,B., Wang,Z.Q., Jin,J., Ren,H.J., Liu,L.N. and Cui,J. Cloning, expression and characterization of a Trichinella spiralis serine protease gene encoding a 35.5kDa protein Exp Parasitol (2013) 134, 148-154. PubMed Europe PubMed DOI E

2012

Arockiaraj,J., Easwvaran,S., Vanaraja,P., Singh,A., Othman,R.Y. and Bhassu,S. Prophenoloxidase activating enzyme-III from giant freshwater prawn Macrobrachium rosenbergii: characterization, expression and specific enzyme activity Mol Biol Rep (2012) 39, 1377-1386. PubMed Europe PubMed DOI
Feng,W. and Zhang,S. A trypsin homolog in amphioxus: expression, enzymatic activity and evolution Mol Biol Rep (2012) 39, 1745-1753. PubMed Europe PubMed DOI
Ghorbanpour,M., Zokaee Ashtiani,F., Zare Mirakabadi,A. and Zolfagharian,H. Purification and partial characterization of a thrombin-like enzyme (AH144) from venom of iranian snake Agkistrodon halys Iran J Chem Chem Eng (2012) 31, 103-109.
He,Q., Li,H., Zhou,B., Wen,H., Li,J., Xiao,B., Zhang,K., Hodgson,W.C. and Yu,X. TA-2, a thrombin-like enzyme from the Chinese white-lipped green pitviper (Trimeresurus albolabris): isolation, biochemical and biological characterization Blood Coagul Fibrinolysis (2012) 23, 445-453. PubMed Europe PubMed DOI
Jitonnom,J., Lomthaisong,K. and Lee,V.S. Computational design of peptide inhibitor based on modifications of proregion from Plutella xylostella midgut trypsin Chem Biol Drug Des (2012) 79, 583-593. PubMed Europe PubMed DOI I
Li,Q., Cui,Z., Liu,Y., Wang,S. and Song,C. Three clip domain serine proteases (cSPs) and one clip domain serine protease homologue (cSPH) identified from haemocytes and eyestalk cDNA libraries of swimming crab Portunus trituberculatus Fish Shellfish Immunol (2012) 32, 565-571. PubMed Europe PubMed DOI
Li,Q., Cui,Z., Liu,Y., Wang,S. and Song,C. Identification and characterization of two novel types of non-clip domain serine proteases (PtSP and PtSPH1) from cDNA haemocytes library of swimming crab Portunus trituberculatus Fish Shellfish Immunol (2012) 32, 683-692. PubMed Europe PubMed DOI
Menaldo,D.L., Bernardes,C.P., Santos-Filho,N.A., Moura,L., Fuly,A.L., Arantes,E.C. and Sampaio,S.V. Biochemical characterization and comparative analysis of two distinct serine proteases from Bothrops pirajai snake venom Biochimie (2012) 94, 2545-2558. PubMed Europe PubMed DOI
Yuan,Z., Dahms,H.U., Han,L.L., Li,Q.Y., Zhang,Q.Z., Wu,R.J., Tan,J., Zou,X.Y. and Hou,L. Cloning and characterization of a trypsin-like serine protease gene, a novel regeneration-related gene from Apostichopus japonicus Gene (2012) 502, 46-52. PubMed Europe PubMed DOI
Zhang,Y., Xu,W., Ma,B., Huang,K., Song,M., Zhang,N., Zhang,Y., Wang,Y., Dai,Y. and Luo,Y. Isolation and characterisation of a kallikrein-like enzyme from Agkistrodon halys pallas snake venom J Sci Food Agric (2012) 92, 1497-1503. PubMed Europe PubMed DOI
Zhong,L., Zhang,F. and Chang,Y. Gene cloning and function analysis of complement B factor-2 of Apostichopus japonicus Fish Shellfish Immunol (2012) 33, 504-513. PubMed Europe PubMed DOI

2011

Balti,R., Bougherra,F., Bougatef,A., Hayet,B.K., Nedjar-Arroume,N., Dhulster,P., Guillochon,D. and Nasri,M. Chymotrypsin from the hepatopancreas of cuttlefish (Sepia officinalis) with high activity in the hydrolysis of long chain peptide substrates: purification and biochemical characterisation Food Chem (2011) 130, 475-484. DOI
Charoensapsri,W., Amparyup,P., Hirono,I., Aoki,T. and Tassanakajon,A. PmPPAE2, a new class of crustacean prophenoloxidase (proPO)-activating enzyme and its role in PO activation Dev Comp Immunol (2011) 35, 115-124. PubMed Europe PubMed DOI
Georgieva,D., Greunke,K., Arni,R.K. and Betzel,C. Three-dimensional modelling of honeybee venom allergenic proteases: relation to allergenicity Z Naturforsch C J Biosci (2011) 66, 305-312. PubMed Europe PubMed
Jang,I.K., Pang,Z., Yu,J., Kim,S.K., Seo,H.C. and Cho,Y.R. Selectively enhanced expression of prophenoloxidase activating enzyme 1 (PPAE1) at a bacteria clearance site in the white shrimp, Litopenaeus vannamei BMC Immunol (2011) 12, 70-70. PubMed Europe PubMed DOI
Ji,R.S., Sun,Q.Y. and Yi,Y. Purification and characterization of a novel double-stranded serine protease from Protobothrops mucrosquamatus venom Chin Pharmacol Bull (2011) 27, 818-823. DOI
Konarev,A.V., Beaudoin,F., Marsh,J., Vilkova,N.A., Nefedova,L.I., Sivri,D., Koksel,H., Shewry,P.R. and Lovegrove,A. Characterization of a glutenin-specific serine proteinase of Sunn bug Eurygaster integricepts Put J Agric Food Chem (2011) 59, 2462-2470. PubMed Europe PubMed DOI
Ramazanova,A.S., Fil'Kin,S.Yu., Starkov,V.G. and Utkin,Y. Molecular cloning and sequence analysis of cDNAs coding for a serine proteinase and a Kunitz-type inhibitor in the venom gland of the Vipera nikolskii viper Russ J Bioorg Chem (2011) 37, 333-343. DOI
Shin,S.W., Zou,Z. and Raikhel,A.S. A new factor in the Aedes aegypti immune response: CLSP2 modulates melanization EMBO Rep (2011) 12, 938-943. PubMed Europe PubMed DOI
Sinha,D.K., Lakshmi,M., Anuradha,G., Rahman,S.J., Siddiq,E.A., Bentur,J.S. and Nair,S. Serine proteases-like genes in the asian rice gall midge show differential expression in compatible and incompatible interactions with rice Int J Mol Sci (2011) 12, 2842-2852. PubMed Europe PubMed DOI
Soares,T.S., Watanabe,R.M., Lemos,F.J. and Tanaka,A.S. Molecular characterization of genes encoding trypsin-like enzymes from Aedes aegypti larvae and identification of digestive enzymes Gene (2011) 489, 70-75. PubMed Europe PubMed DOI
Vaiyapuri,S., Wagstaff,S.C., Harrison,R.A., Gibbins,J.M. and Hutchinson,E.G. Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros PLoS ONE (2011) 6, e21532-e21532. PubMed Europe PubMed DOI PMC EPMC
Zhao,L., Chen,J., Becnel,J.J., Kline,D.L., Clark,G.G. and Linthicum,K.J. Identification and transcription profiling of trypsin in Aedes taeniorhynchus (Diptera: Culicidae): developmental regulation, blood feeding, and permethrin exposure J Med Entomol (2011) 48, 546-553. PubMed Europe PubMed DOI

2010

Amparyup,P., Wiriyaukaradecha,K., Charoensapsri,W. and Tassanakajon,A. A clip domain serine proteinase plays a role in antibacterial defense but is not required for prophenoloxidase activation in shrimp Dev Comp Immunol (2010) 34, 168-176. PubMed Europe PubMed DOI
Brackney,D.E., Isoe,J., Black,W.C.4., Zamora,J., Foy,B.D., Miesfeld,R.L. and Olson,K.E. Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegypti J Insect Physiol (2010) 56, 736-744. PubMed Europe PubMed DOI
Broehan,G., Arakane,Y., Beeman,R.W., Kramer,K.J., Muthukrishnan,S. and Merzendorfer,H. Chymotrypsin-like peptidases from Tribolium castaneum: a role in molting revealed by RNA interference Insect Biochem Mol Biol (2010) 40, 274-283. PubMed Europe PubMed DOI
Chernyshenko,V.O., Gornytska,O.V., Platonova,T.M. and Sokolovska,L.I. A new fibrinogenase from Echis multisquamatis venom is a perspective agent for limited proteolysis and defibrinogenation Adv.Biosci.Biotechnol. (2010) 1, 91-96.
Hasson,S.S., Mothana,R.A., Sallam,T.A., Al-balushi,M.S., Rahman,M.T. and Al-Jabri,A.A. Serine protease variants encoded by Echis ocellatus venom gland cDNA: cloning and sequencing analysis J Biomed Biotechnol (2010) 2010, 134232-134232. PubMed Europe PubMed DOI PMC EPMC
Meiser,C.K., Piechura,H., Meyer,H.E., Warscheid,B., Schaub,G.A. and Balczun,C. A salivary serine protease of the haematophagous reduviid Panstrongylus megistus: sequence characterization, expression pattern and characterization of proteolytic activity Insect Mol Biol (2010) 19, 409-421. PubMed Europe PubMed DOI
Sun,T., Zhang,S. and Ji,G. Identification and expression of an elastase homologue in Branchiostoma belcheri with implications to the origin of vertebrate pancreas Mol Biol Rep (2010) 37, 3303-3309. PubMed Europe PubMed DOI
Tan,N.H. Isolation and characterization of the thrombin-like enzyme from Cryptelytrops purpureomaculatus venom Comp Biochem Physiol C Toxicol Pharmacol (2010) 151, 131-136. PubMed Europe PubMed DOI
Toubarro,D., Lucena-Robles,M., Nascimento,G., Santos,R., Montiel,R., Verissimo,P., Pires,E., Faro,C., Coelho,A.V. and Simoes,N. Serine protease-mediated host invasion by the parasitic nematode Steinernema carpocapsae J Biol Chem (2010) 285, 30666-30675. PubMed Europe PubMed DOI
Vaiyapuri,S., Harrison,R.A., Bicknell,A.B., Gibbins,J.M. and Hutchinson,G. Purification and functional characterisation of rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros PLoS ONE (2010) 5, e9687-e9687. PubMed Europe PubMed DOI PMC EPMC

2009

Balasubramanian,N., Hao,Y.J., Toubarro,D., Nascimento,G. and Simoes,N. Purification, biochemical and molecular analysis of a chymotrypsin protease with prophenoloxidase suppression activity from the entomopathogenic nematode Steinernema carpocapsae Int J Parasitol (2009) 39, 975-984. PubMed Europe PubMed DOI
Gai,Y., Qiu,L., Wang,L., Song,L., Mu,C., Zhao,J., Zhang,Y. and Li,L. A clip domain serine protease (cSP) from the Chinese mitten crab Eriocheir sinensis: cDNA characterization and mRNA expression Fish Shellfish Immunol (2009) 27, 670-677. PubMed Europe PubMed DOI
Hao,Y.J., Montiel,R., Nascimento,G., Toubarro,D. and Simoes,N. Identification and expression analysis of the Steinernema carpocapsae elastase-like serine protease gene during the parasitic stage Exp Parasitol (2009) 122, 51-60. PubMed Europe PubMed DOI
Isoe,J., Rascon,A.A., Jr., Kunz,S. and Miesfeld,R.L. Molecular genetic analysis of midgut serine proteases in Aedes aegypti mosquitoes Insect Biochem Mol Biol (2009) 39, 903-912. PubMed Europe PubMed DOI
Klomklao,S., Kishimura,H., Nonami,Y. and Benjakul,S. Biochemical properties of two isoforms of trypsin purified from the intestine of skipjack tuna (Katsuwonus pelamis) Food Chem (2009) 115, 155-162. DOI
Liao,E.C., Hsu,E.L., Tsai,J.J. and Ho,C.M. Immunologic characterization and allergenicity of recombinant Tyr p 3 allergen from the storage mite Tyrophagus putrescentiae Int Arch Allergy Immunol (2009) 150, 15-24. PubMed Europe PubMed DOI
Liu,M. and Zhang,S. A kringle-containing protease with plasminogen-like activity in the basal chordate Branchiostoma belcheri Biosci Rep (2009) 29, 385-395. PubMed Europe PubMed DOI
Ren,Q., Xu,Z.L., Wang,X.W., Zhao,X.F. and Wang,J.X. Clip domain serine protease and its homolog respond to Vibrio challenge in Chinese white shrimp, Fenneropenaeus chinensis Fish Shellfish Immunol (2009) 26, 787-798. PubMed Europe PubMed DOI
Skern-Mauritzen,R., Frost,P., Dalvin,S., Kvamme,B.O., Sommerset,I. and Nilsen,F. A trypsin-like protease with apparent dual function in early Lepeophtheirus salmonis (Kroyer) development BMC Mol Biol (2009) 10, 44-44. PubMed Europe PubMed DOI PMC EPMC
Tang,S.S., Zhang,J.H., Tang,B.S., Tang,Z.H., Li,H.Z., Yuan,H.J., Chui,S.L. and Zhao,E.Y. Biochemical and hemostatic mechanism of a novel thrombin-like enzyme Thromb Res (2009) 124, 631-639. PubMed Europe PubMed DOI
Toubarro,D., Lucena-Robles,M., Nascimento,G., Costa,G., Montiel,R., Coelho,A.V. and Simoes,N. An apoptosis-inducing serine protease secreted by the entomopathogenic nematode Steinernema carpocapsae Int J Parasitol (2009) 39, 1319-1330. PubMed Europe PubMed DOI

2008

Broehan,G., Kemper,M., Driemeier,D., Vogelpohl,I. and Merzendorfer,H. Cloning and expression analysis of midgut chymotrypsin-like proteinases in the tobacco hornworm J Insect Physiol (2008) 54, 1243-1252. PubMed Europe PubMed DOI
Liu,S., Sun,M.Z., Sun,C., Zhao,B., Greenaway,F.T. and Zheng,Q. A novel serine protease from the snake venom of Agkistrodon blomhoffii ussurensis Toxicon (2008) 52, 760-768. PubMed Europe PubMed DOI
Ma,B., Zhang,Y., Wu,D., Jia,J., Xu,W. and Luo,Y. Affinity-purification of fibrinogenase with high proteolytic activity from Agkistrodon halys (Chinese) venom Arch Pharm Res (2008) 31, 1129-1136. PubMed Europe PubMed DOI
Miyoshi,T., Tsuji,N., Islam,M.K., Alim,M.A., Hatta,T., Huang,X. and Fujisaki,K. A set of serine proteinase paralogs are required for blood-digestion in the ixodid tick Haemaphysalis longicornis Parasitol Int (2008) 57, 499-505. PubMed Europe PubMed DOI
Zhu,L., Song,L., Mao,Y., Zhao,J., Li,C. and Xu,W. A novel serine protease with clip domain from scallop Chlamys farreri Mol Biol Rep (2008) 35, 257-264. PubMed Europe PubMed DOI

2007

Brioschi,D., Nadalini,L.D., Bengtson,M.H., Sogayar,M.C., Moura,D.S. and Silva-Filho,M.C. General up regulation of Spodoptera frugiperda trypsins and chymotrypsins allows its adaptation to soybean proteinase inhibitor Insect Biochem Mol Biol (2007) 37, 1283-1290. PubMed Europe PubMed DOI
Hwang,J.Y., Hirono,I. and Aoki,T. Cloning and expression of a novel serine protease from Japanese flounder, Paralichthys olivaceus Dev Comp Immunol (2007) 31, 587-595. PubMed Europe PubMed DOI
Jin,Y., Lee,W.H. and Zhang,Y. Molecular cloning of serine proteases from elapid snake venoms Toxicon (2007) 49, 1200-1207. PubMed Europe PubMed DOI
Magalhaes,C.P., Fragoso,R.R., Souza,D.S., Barbosa,A.E., Silva,C.P., Finardi-Filho,F., da Silva,M.C., Rocha,T.L., Franco,O.L. and Grossi-de-Sa,M.F. Molecular and structural characterization of a trypsin highly expressed in larval stage of Zabrotes subfasciatus Arch Insect Biochem Physiol (2007) 66, 169-182. PubMed Europe PubMed DOI
Wang,D., Liu,W., Han,B. and Xu,R. Biochemical and enzymatic properties of a novel marine fibrinolytic enzyme from Urechis unicinctus Appl Biochem Biotechnol (2007) 136, 251-264. PubMed Europe PubMed DOI
Wei,Z., Yin,Y., Zhang,B., Wang,Z., Peng,G., Cao,Y. and Xia,Y. Cloning of a novel protease required for the molting of Locusta migratoria manilensis Dev Growth Differ (2007) 49, 611-621. PubMed Europe PubMed DOI

2006

[YEAR:9-12-2006]Abdallah,J., Kern,R., Malki,A., Eckey,V. and Richarme,G. Cloning, expression, and purification of the general stress protein YhbO from Escherichia coli Protein Expr Purif (9-12-2006) 47, 455-460. PubMed Europe PubMed DOI
Paskewitz,S.M., Andreev,O. and Shi,L. Gene silencing of serine proteases affects melanization of Sephadex beads in Anopheles gambiae Insect Biochem Mol Biol (2006) 36, 701-711. PubMed Europe PubMed DOI
[YEAR:9-2-2006]Praveen,K., Leary,J.H., III, Evans,D.L. and Jaso-Friedmann,L. Molecular characterization and expression of a granzyme of an ectothermic vertebrate with chymase-like activity expressed in the cytotoxic cells of Nile tilapia (Oreochromis niloticus) Immunogenetics (9-2-2006) 58, 41-55. PubMed Europe PubMed DOI
[YEAR:29-8-2006]Praveen,K., Leary,J.H., III, Evans,D.L. and Jaso-Friedmann,L. Nonspecific cytotoxic cells of teleosts are armed with multiple granzymes and other components of the granule exocytosis pathway Mol Immunol (29-8-2006) 43, 1152-1162. PubMed Europe PubMed DOI
Srinivasan,A., Giri,A.P. and Gupta,V.S. Structural and functional diversities in lepidopteran serine proteases Cell Mol Biol Lett (2006) 11, 132-154. PubMed Europe PubMed DOI
Xu,J., Baldwin,D., Kindrachuk,C. and Hegedus,D.D. Serine proteases and metalloproteases associated with pathogenesis but not host specificity in the Entomophthoralean fungus Zoophthora radicans Can J Microbiol (2006) 52, 550-559. PubMed Europe PubMed DOI
[YEAR:17-2-2006]Yan,J.B., Wang,G.Q., Du,P., Zhu,D.X., Wang,M.W. and Jiang,X.Y. High-level expression and purification of Escherichia coli oligopeptidase B Protein Expr Purif (17-2-2006) 47, 645-650. PubMed Europe PubMed DOI E

2005

[YEAR:9-11-2005]Cal,S., Quesada,V., Llamazares,M., Diaz-Perales,A., Garabaya,C. and Lopez-Otin,C. Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain J Biol Chem (9-11-2005) 280, 1953-1961. PubMed Europe PubMed DOI
[YEAR:10-2-2005]Chen,B., Kayukawa,T., Jiang,H., Monteiro,A., Hoshizaki,S. and Ishikawa,Y. DaTrypsin, a novel clip-domain serine proteinase gene up-regulated during winter and summer diapauses of the onion maggot, Delia antiqua Gene (10-2-2005) 347, 115-123. PubMed Europe PubMed DOI
[YEAR:19-4-2005]Elpidina,E.N., Tsybina,T.A., Dunaevsky,Y.E., Belozersky,M.A., Zhuzhikov,D.P. and Oppert,B. A chymotrypsin-like proteinase from the midgut of Tenebrio molitor larvae Biochimie (19-4-2005) 87, 771-779. PubMed Europe PubMed DOI
Fragoso,R.R., Batista,J.A., Neto,O.B. and Grossi de Sa,M.F. Isolation and characterization of a cDNA encoding a serine proteinase from the root-knot nematode Meloidogyne incognita Exp Parasitol (2005) 110, 123-133. PubMed Europe PubMed DOI
[YEAR:9-4-2005]Gong,M., Shen,B., Gu,Y., Tian,H., Ma,L., Li,X., Yang,M., Hu,Y., Sun,Y., Hu,X., Li,J. and Zhu,C. Serine proteinase over-expression in relation to deltamethrin resistance in Culex pipiens pallens Arch Biochem Biophys (9-4-2005) 438, 53-62. PubMed Europe PubMed DOI
Gupta,S., Wang,Y. and Jiang,H. Purification and characterization of Manduca sexta prophenoloxidase-activating proteinase-1, an enzyme involved in insect immune responses Protein Expr Purif (2005) 39, 261-268. PubMed Europe PubMed DOI
Gupta,S., Wang,Y. and Jiang,H. Manduca sexta prophenoloxidase (proPO) activation requires proPO-activating proteinase (PAP) and serine proteinase homologs (SPHs) simultaneously Insect Biochem Mol Biol (2005) 35, 241-248. PubMed Europe PubMed DOI PMC EPMC
[YEAR:5-5-2005]Kvamme,B.O., Kongshaug,H. and Nilsen,F. Organisation of trypsin genes in the salmon louse (Lepeophtheirus salmonis, Crustacea, copepoda) genome Gene (5-5-2005) 352, 63-74. PubMed Europe PubMed DOI
Li,J., Choo,Y.M., Lee,K.S., Je,Y.H., Woo,S.D., Kim,I., Sohn,H.D. and Jin,B.R. A serine protease gene from the firefly, Pyrocoelia rufa: gene structure, expression, and enzyme activity Biotechnol Lett (2005) 27, 1051-1057. PubMed Europe PubMed DOI
Ock,M.S., Kim,B.J., Kim,S.M. and Byun,K.H. Cloning and expression of trypsin-encoding cDNA from Blattella germanica and its possibility as an allergen Korean J Parasitol (2005) 43, 101-110. PubMed Europe PubMed PMC EPMC
Ohkubo,M., Osatomi,K., Hara,K., Ishihara,T. and Aranishi,F. A novel type of myofibril-bound serine protease from white croaker (Argyrosomus argentatus) Comp Biochem Physiol B Biochem Mol Biol (2005) 141, 231-236. PubMed Europe PubMed DOI
[YEAR:15-4-2005]Szenthe,B., Frost,C., Szilagyi,L., Patthy,A., Naude,R. and Graf,L. Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site Biochim Biophys Acta (15-4-2005) 1748, 35-42. PubMed Europe PubMed DOI
Tsybina,T.A., Dunaevsky,Y.E., Belozersky,M.A., Zhuzhikov,D.P., Oppert,B. and Elpidina,E.N. Digestive proteinases of Yellow mealworm (Tenebrio molitor) larvae: purification and characterization of a trypsin-like proteinase Biochemistry (Mosc) (2005) 70, 300-305. PubMed Europe PubMed DOI

2004

Behrens,M., Bufe,B., Schmale,H. and Meyerhof,W. Molecular cloning and characterisation of DESC4, a new transmembrane serine protease Cell Mol Life Sci (2004) 61, 2866-2877. PubMed Europe PubMed DOI
[YEAR:3-8-2004]Johns,M.E., Tai,P.C. and Derby,C.D. Serine proteases in the spiny lobster olfactory organ: their functional expression along a developmental axis, and the contribution of a CUB-serine protease J Neurobiol (3-8-2004) 61, 377-391. PubMed Europe PubMed DOI
Kvamme,B.O., Skern,R., Frost,P. and Nilsen,F. Molecular characterisation of five trypsin-like peptidase transcripts from the salmon louse (Lepeophtheirus salmonis) intestine Int J Parasitol (2004) 34, 823-832. PubMed Europe PubMed DOI
[YEAR:26-1-2004]Okamoto,Y., Takai,S. and Miyazaki,M. Significance of chymase inhibition for prevention of adhesion formation Eur J Pharmacol (26-1-2004) 484, 357-359. PubMed Europe PubMed DOI I
Oliveira-Neto,O.B., Batista,J.A., Rigden,D.J., Fragoso,R.R., Silva,R.O., Gomes,E.A., Franco,O.L., Dias,S.C., Cordeiro,C.M., Monnerat,R.G. and Grossi-de-Sa,M.F. A diverse family of serine proteinase genes expressed in cotton boll weevil (Anthonomus grandis): implications for the design of pest-resistant transgenic cotton plants Insect Biochem Mol Biol (2004) 34, 903-918. PubMed Europe PubMed DOI
Praveen,K., Evans,D.L. and Jaso-Friedmann,L. Evidence for the existence of granzyme-like serine proteases in teleost cytotoxic cells J Mol Evol (2004) 58, 449-459. PubMed Europe PubMed DOI

2003

Nagano,I., Wu,Z., Nakada,T., Boonmars,T. and Takahashi,Y. Molecular cloning and characterization of a serine proteinase gene of Trichinella spiralis J Parasitol (2003) 89, 92-98. PubMed Europe PubMed DOI
[YEAR:1-2-2003]Rao,V.S., Joseph,J.S. and Kini,R.M. Group D prothrombin activators from snake venom are structural homologues of mammalian blood coagulation factor Xa Biochem J (1-2-2003) 369, 635-642. PubMed Europe PubMed DOI PMC EPMC

2002

[YEAR:1-4-2002]Roach,J.C. A clade of trypsins found in cold-adapted fish Proteins (1-4-2002) 47, 31-44. PubMed Europe PubMed DOI
Rojas,A. and Doolittle,R.F. The occurrence of type S1A serine proteases in sponge and jellyfish J Mol Evol (2002) 55, 790-794.
Yang,Q., Hu,X.J., Xu,X.M., An,L.J., Yuan,X.D. and Su,Z.G. Cloning, expression and purification of gussurobin, a thrombin-like enzyme from the snake venom of Gloydius ussuriensis Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2002) 34, 6-10. PubMed Europe PubMed
Zeng,F., Zhu,Y. and Cohen,A. Partial characterization of trypsin-like protease and molecular cloning of a trypsin-like precursor cDNA in salivary glands of Lygus lineolaris Comp Biochem Physiol B Biochem Mol Biol (2002) 131, 453-463. PubMed Europe PubMed DOI

2001

[YEAR:1-3-2001]Gorman,M.J. and Paskewitz,S.M. Serine proteases as mediators of mosquito immune responses Insect Biochem Mol Biol (1-3-2001) 31, 257-262. PubMed Europe PubMed DOI
Nakao,M., Osaka,K., Kato,Y., Fujiki,K. and Yano,T. Molecular cloning of the complement C1r/C1s/MASP2-like serine proteases from the common carp (Cyprinus carpio) Immunogenetics (2001) 52, 255-263. PubMed Europe PubMed DOI
[YEAR:15-2-2001]Wang,Y.M., Wang,S.R. and Tsai,I.H. Serine protease isoforms of Deinagkistrodon acutus venom: cloning, sequencing and phylogenetic analysis Biochem J (15-2-2001) 354, 161-168. PubMed Europe PubMed DOI PMC EPMC

2000

Chen,Y., Shiota,M., Ohuchi,M., Towatari,T., Tashiro,J., Murakami,M., Yano,M., Yang,B. and Kido,H. Mast cell tryptase from pig lungs triggers infection by pneumotropic Sendai and influenza A viruses. Purification and characterization Eur J Biochem (2000) 267, 3189-3197. PubMed Europe PubMed DOI
Gorman,M.J., Andreeva,O.V. and Paskewitz,S.M. Molecular characterization of five serine protease genes cloned from Anopheles gambiae hemolymph Insect Biochem Mol Biol (2000) 30, 35-46. PubMed Europe PubMed DOI
[YEAR:7-3-2000]Matsui,T., Fujimura,Y. and Titani,K. Snake venom proteases affecting hemostasis and thrombosis Biochim Biophys Acta (7-3-2000) 1477, 146-156. PubMed Europe PubMed DOI
Poorafshar,M., Aveskogh,M., Munday,B. and Hellman,L. Identification and structural analysis of four serine proteases in a monotreme, the platypus, Ornithorhynchus anatinus Immunogenetics (2000) 52, 19-28. PubMed Europe PubMed DOI
Serrano,S.M., Sampaio,C.A., Mentele,R., Camargo,A.C. and Fink,E. A novel fibrinogen-clotting enzyme, TL-BJ, from the venom of the snake Bothrops jararaca: purification and characterization Thromb Haemost (2000) 83, 438-444. PubMed Europe PubMed

1999

Andriao-Escarso,S.H., Soares,A.M., Rodrigues,V.M., Mancin,A.C., Reis,M.L., Ballejo,G. and Giglio,J.R. Isolation and characterization of an arginine ester hydrolase from Bothrops jararacussu venom which induces contractions of the isolated rat uterus Biochem Mol Biol Int (1999) 47, 699-706. PubMed Europe PubMed
Lam,W., Coast,G.M. and Rayne,R.C. Isolation and characterisation of two chymotrypsins from the midgut of Locusta migratoria Insect Biochem Mol Biol (1999) 29, 653-660.
Whitworth,S.T., Kordula,T. and Travis,J. Molecular cloning of Soli E2: an elastase-like serine proteinase from the imported red fire ant (Solenopsis invicta) Insect Biochem Mol Biol (1999) 29, 249-254. PubMed Europe PubMed DOI

1998

[YEAR:4-9-1998]Davies,B.J., Pickard,B.S., Steel,M., Morris,R.G. and Lathe,R. Serine proteases in rodent hippocampus J Biol Chem (4-9-1998) 273, 23004-23011. PubMed Europe PubMed DOI
Hajnik,C.A., Goetz,F.W., Hsu,S.Y. and Sokal,N. Characterization of a ribonucleic acid transcript from the brook trout (Salvelinus fontinalis) ovary with structural similarities to mammalian adipsin/complement factor D and tissue kallikrein, and the effects of kallikrein-like serine proteases on follicle contraction Biol Reprod (1998) 58, 887-897. PubMed Europe PubMed DOI
[YEAR:1-6-1998]Lehane,S.M., Assinder,S.J. and Lehane,M.J. Cloning, sequencing, temporal expression and tissue-specificity of two serine proteases from the midgut of the blood-feeding fly Stomoxys calcitrans Eur J Biochem (1-6-1998) 254, 290-296. PubMed Europe PubMed DOI
Taguchi,S., Yamada,S., Kojima,S. and Momose,H. An endogenous target protease, SAM-P26, of Streptomyces protease inhibitor (SSI): Primary structure, enzymatic characterization, and its interaction with SSI J Biochem (1998) 124, 804-810. PubMed Europe PubMed
[YEAR:5-6-1998]Whitworth,S.T., Blum,M.S. and Travis,J. Proteolytic enzymes from larvae of the fire ant, Solenopsis invicta. Isolation and characterization of four serine endopeptidases J Biol Chem (5-6-1998) 273, 14430-14434. PubMed Europe PubMed DOI

1997

Andriao-Escarso,S.H., Sampaio,S.V., Cunha,O.A., Marangoni,S., Oliveira,B. and Giglio,J.R. Isolation and characterization of a new clotting factor from Bothrops jararacussu (jararacucu) venom Toxicon (1997) 35, 1043-1052. PubMed Europe PubMed DOI
Gatehouse,L.N., Shannon,A.L., Burgess,E.P. and Christeller,J.T. Characterization of major midgut proteinase cDNAs from Helicoverpa armigera larvae and changes in gene expression in response to four proteinase inhibitors in the diet Insect Biochem Mol Biol (1997) 27, 929-944. PubMed Europe PubMed DOI
Giovanni-De-Simone,S., Aguiar,A.S., Gimenez,A.R., Novellino,K. and de Moura,R.S. Purification, properties, and N-terminal amino acid sequence of a kallikrein-like enzyme from the venom of Lachesis muta rhombeata (Bushmaster) J Protein Chem (1997) 16, 809-818. PubMed Europe PubMed DOI
Lilley,C.J., Urwin,P.E., Atkinson,H.J. and McPherson,M.J. Characterization of cDNAs encoding serine proteinases from the soybean cyst nematode Heterodera glycines Mol Biochem Parasitol (1997) 89, 195-207. PubMed Europe PubMed DOI
Zhu,Y.C., Oppert,B., Kramer,K.J., McGaughey,W.H. and Dowdy,A.K. cDNAs for a chymotrypsinogen-like protein from two strains of Plodia interpunctella Insect Biochem Mol Biol (1997) 27, 1027-1037. PubMed Europe PubMed DOI

1996

Fisseha,M., Gloudemans,M., Gill,R.E. and Kroos,L. Characterization of the regulatory region of a cell interaction-dependent gene in Myxococcus xanthus J Bacteriol (1996) 178, 2539-2550. PubMed Europe PubMed
Lao,G. and Wilson,D.B. Cloning, sequencing, and expression of a Thermomonospora fusca protease gene in Streptomyces lividans Appl Environ Microbiol (1996) 62, 4256-4259. PubMed Europe PubMed PMC EPMC
Richards,G.P., Zintz,C., Chao,J. and Chao,L. Purification and characterization of salivary kallikrein from an insectivore (Scalopus aquaticus): substrate specificities, immunoreactivity, and kinetic analyses Arch Biochem Biophys (1996) 329, 104-112. PubMed Europe PubMed DOI

1995

Chang,M.C. and Huang,T.F. Characterization of a thrombin-like enzyme, grambin, from the venom of Trimeresurus gramineus and its in vivo antithrombotic effect Toxicon (1995) 33, 1087-1098. PubMed Europe PubMed DOI
Richards,G.P., Chao,J., Chung,P. and Chao,L. Purification and characterization of tissue kallikrein-like proteinases from the black sea bass (Centropristis striata) and the southern frog (Rana berlandieri) Comp Biochem Physiol C Pharmacol Toxicol Endocrinol (1995) 111, 69-82. PubMed Europe PubMed DOI

1993

Bakker,H.M., Tans,G., Yukelson,L.Y., Janssen-Claessen,T.W., Bertina,R.M., Hemker,H.C. and Rosing,J. Protein C activation by an activator purified from the venom of Agkistrodon halys halys Blood Coagul Fibrinolysis (1993) 4, 605-614. PubMed Europe PubMed
Sasaki,T., Hishida,T., Ichikawa,K. and Asari,S. Amino acid sequence of alkaliphilic serine protease from silkworm, Bombyx mori, larval digestive juice FEBS Lett (1993) 320, 35-37. PubMed Europe PubMed DOI
Tans,G. and Rosing,J. Prothrombin activation by snake venom proteases J Toxicol Toxin Rev (1993) 12, 155-173.
Utaisincharoen,P., Mackessy,S.P., Miller,R.A. and Tu,A.T. Complete primary structure and biochemical properties of gilatoxin, a serine protease with kallikrein-like and angiotensin- degrading activities J Biol Chem (1993) 268, 21975-21983. PubMed Europe PubMed

1992

Kido,H., Yokogoshi,Y., Sakai,K., Tashiro,M., Kishino,Y., Fukutomi,A. and Katunuma,N. Isolation and characterization of a novel trypsin-like protease found in rat bronchiolar epithelial Clara cells. A possible activator of the viral fusion glycoprotein J Biol Chem (1992) 267, 13573-13579. PubMed Europe PubMed
Tashiro,M., Yokogoshi,Y., Tobita,K., Seto,J.T., Rott,R. and Kido,H. Tryptase Clara, an activating protease for Sendai virus in rat lungs, is involved in pneumopathogenicity J Virol (1992) 66, 7211-7216. PubMed Europe PubMed PMC EPMC

1989

Williams,V. and White,J. Purification and properties of a procoagulant from peninsula tiger snake (Notechis ater niger) venom Toxicon (1989) 27, 773-779. PubMed Europe PubMed

1988

Sakal,E., Applebaum,S.W. and Birk,Y. Purification and characterization of Locusta migratoria chymotrypsin Int J Pept Protein Res (1988) 32, 590-598. PubMed Europe PubMed

1987

[YEAR:15-6-1987]Evans,B.A., Drinkwater,C.C. and Richards,R.I. Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus J Biol Chem (15-6-1987) 262, 8027-8034. PubMed Europe PubMed
Francis,R.B., Jr. and Seyfert,U. Rapid amidolytic assay of protein C in whole plasma using an activator from the venom of Agkistrodon contortrix Am J Clin Pathol (1987) 87, 619-625. PubMed Europe PubMed

1978

Jany,K.D., Haug,H. and Ishay,J. Trypsin-like endopeptidases from the midguts of the larvae from the hornets of Vespa orientalis and Vespa crabro Insect Biochemistry (1978) 8, 221-230.

1977

Narahashi,Y. and Yoda,K. Alkaline serine proteinases D and E of Streptomyces griseus K-1 J Biochem (1977) 81, 587-597. PubMed Europe PubMed

1976

Narahashi,Y. and Yoda,K. Alkaline proteinase E of Streptomyces griseus K-1 J Biochem (1976) 79, 1119-1122. PubMed Europe PubMed I