Literature for peptidase S01.285

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: T Target, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Lin,Y., Liu,Z., Yang,J., Li,X., Hu,Y., Gao,L., Li,X., Bi,Y. and Wang,Y.
    Placental Pathology and HTRA4-Mediated Autophagic Flux Disruption in Selective Fetal Growth Restriction Types I and III: A Morphological and Transcriptomic Study
    FASEB J (2026) 40, e71471-e71471. PubMed  Europe PubMed DOI
  2. 2025
  3. Kong,H., Ma,X., Wang,F., Su,Y., Chang,Y. and Xin,H.
    Htra4 promotes vascular endothelial cell injury and is associated with the early-onset of preeclampsia
    Sci Rep (2025) 15, 11752-11752. PubMed  Europe PubMed DOI  PMC  EPMC
  4. 2024
  5. Donohoe,M.E., Morey,R., Li,Y., Pizzo,D., Kallol,S., Cho,H.Y., Soncin,F. and Parast,M.M.
    Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast
    Am J Pathol (2024) 194, 1162-1170. PubMed  Europe PubMed DOI  K
  6. Rosochowicz,M.A., Kulcenty,K. and Suchorska,W.M.
    Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review
    Mol Diagn Ther (2024) 28, 347-377. PubMed  Europe PubMed DOI  V
  7. 2021
  8. Fantone,S., Giannubilo,S.R., Marzioni,D. and Tossetta,G.
    HTRA family proteins in pregnancy outcome
    Tissue Cell (2021) 72, 101549-101549. PubMed  Europe PubMed DOI
  9. 2019
  10. Kummari,R., Dutta,S., Chaganti,L.K. and Bose,K.
    Discerning the mechanism of action of HtrA4: a serine protease implicated in the cell death pathway
    Biochem J (2019) 476, 1445-1463. PubMed  Europe PubMed DOI
  11. Tseng,E., Yee Teoh,S.S., Wang,Y. and Nie,G.
    Elevated protease HtrA4 in the maternal circulation of preeclampsia may contribute to endothelial barrier disruption by cleaving key junctional protein VE-cadherin
    Placenta (2019) 76, 51-53. PubMed  Europe PubMed DOI
  12. Wenta,T., Jarzab,M., Rychlowski,M., Borysiak,M., Latala,A., Zurawa-Janicka,D., Filipek,A. and Lipinska,B.
    Cellular substrates and pro-apoptotic function of the human HtrA4 protease
    J Proteomics (2019) 209, 103505-103505. PubMed  Europe PubMed DOI
  13. Wenta,T., Rychlowski,M., Jarzab,M. and Lipinska,B.
    HtrA4 Protease promotes chemotherapeutic-dependent cancer cell death
    Cells (2019) 8 PubMed  Europe PubMed DOI
  14. 2018
  15. Sun,M.L., Sun,L.M. and Wang,Y.Q.
    Peptide selectivity between the PDZ domains of human pregnancy-related serine proteases (HtrA1, HtrA2, HtrA3, and HtrA4) can be reshaped by different halogen probes
    J Mol Recognit (2018) 31, e2698-e2698. PubMed  Europe PubMed DOI  I
  16. 2017
  17. Zurawa-Janicka,D., Wenta,T., Jarzab,M., Skorko-Glonek,J., Glaza,P., Gieldon,A., Ciarkowski,J. and Lipinska,B.
    Structural insights into the activation mechanisms of human HtrA serine proteases
    Arch Biochem Biophys (2017) 621, 6-23. PubMed  Europe PubMed DOI  V
  18. 2014
  19. Chen,Y.Y., Chuang,P.Y., Chen,C.P., Chiu,Y.H., Lo,H.F., Cheong,M.L., Huang,J.Y., Kuo,P.L. and Chen,H.
    Functional antagonism between high temperature requirement protein A (HtrA) family members regulates trophoblast invasion
    J Biol Chem (2014) 289, 22958-22968. PubMed  Europe PubMed DOI
  20. 2012
  21. Chien,J. and Shridhar,V.
    HtrA1 peptidase
    [ISSN:978-0-12-407742-3] (2012) 3, 2577-2584. DOI
  22. 2011
  23. Clausen,T., Kaiser,M., Huber,R. and Ehrmann,M.
    HTRA proteases: regulated proteolysis in protein quality control
    Nat Rev Mol Cell Biol (2011) 12, 152-162. PubMed  Europe PubMed DOI  V
  24. 2009
  25. Chien,J., Campioni,M., Shridhar,V. and Baldi,A.
    HtrA serine proteases as potential therapeutic targets in cancer
    Curr Cancer Drug Targets (2009) 9, 451-468. PubMed  Europe PubMed DOI  T
  26. 2004
  27. Dingwall,C. and Holbrook,J.D.
    Human HtrA proteases
    [ISSN:0-12-079610-4] (2004) 2, 1476-1480.  V