Literature for peptidase S01.284: HtrA3 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, T Target, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, R Splicing. To select only the references relevant to a single topic, click the link above. See explanation.)

2024

Rosochowicz,M.A., Kulcenty,K. and Suchorska,W.M. Exploring the Role of HtrA Family Genes in Cancer: A Systematic Review Mol Diagn Ther (2024) 28, 347-377. PubMed Europe PubMed DOI V

2023

Tong,Z., Shen,Y., Yuan,Q. and Yu,H. HTRA3 transcriptionally inhibited by FOXP1 suppresses tumorigenesis of osteosarcoma via the PTEN/PI3K/AKT pathway Biochim Biophys Acta Mol Cell Res (2023) 1870, 119553-119553. PubMed Europe PubMed DOI K

2022

Ko,T., Nomura,S., Yamada,S., Fujita,K., Fujita,T., Satoh,M., Oka,C., Katoh,M., Ito,M., Katagiri,M., Sassa,T., Zhang,B., Hatsuse,S., Yamada,T., Harada,M., Toko,H., Amiya,E., Hatano,M., Kinoshita,O., Nawata,K., Abe,H., Ushiku,T., Ono,M., Ikeuchi,M., Morita,H., Aburatani,H. and Komuro,I. Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-beta-IGFBP7 axis Nat Commun (2022) 13, 3275-3275. PubMed Europe PubMed DOI PMC EPMC
Shen,Z., Sun,F., Lu,Y., Yuan,L., Ge,S., Gong,Q. and Shi,H. High temperature requirement A3 attenuates hypoxia/reoxygenation induced injury in H9C2 cells via suppressing inflammatory responses Eur J Pharmacol (2022) 928, 175114-175114. PubMed Europe PubMed DOI K

2021

Fantone,S., Giannubilo,S.R., Marzioni,D. and Tossetta,G. HTRA family proteins in pregnancy outcome Tissue Cell (2021) 72, 101549-101549. PubMed Europe PubMed DOI

2020

Acharya,S., Dutta,S. and Bose,K. A distinct concerted mechanism of structural dynamism defines activity of human serine protease HtrA3 Biochem J (2020) 477, 407-429. PubMed Europe PubMed DOI

2019

Acharya,S., Dutta,S., Chopra,S. and Bose,K. Identification of a distal allosteric ligand binding pocket in HtrA3 Biochem Biophys Res Commun (2019) 516, 1130-1136. PubMed Europe PubMed DOI
Wenta,T., Rychlowski,M., Jurewicz,E., Jarzab,M., Zurawa-Janicka,D., Filipek,A. and Lipinska,B. The HtrA3 protease promotes drug-induced death of lung cancer cells by cleavage of the X-linked inhibitor of apoptosis protein (XIAP) FEBS J (2019) 286, 4579-4596. PubMed Europe PubMed DOI

2018

Sun,M.L., Sun,L.M. and Wang,Y.Q. Peptide selectivity between the PDZ domains of human pregnancy-related serine proteases (HtrA1, HtrA2, HtrA3, and HtrA4) can be reshaped by different halogen probes J Mol Recognit (2018) 31, e2698-e2698. PubMed Europe PubMed DOI I
Wang,Y., Li,Y., Hyett,J., da Silva Costa,F. and Nie,G. HtrA3 isoform-specific ELISAs for early detection of preeclampsia J Biomol Screen (2018) 23, 1092-1099. PubMed Europe PubMed DOI R
Wenta,T., Zurawa-Janicka,D., Rychlowski,M., Jarzab,M., Glaza,P., Lipinska,A., Bienkowska-Szewczyk,K., Herman-Antosiewicz,A., Skorko-Glonek,J. and Lipinska,B. HtrA3 is a cellular partner of cytoskeleton proteins and TCP1alpha chaperonin J Proteomics (2018) 177, 88-111. PubMed Europe PubMed DOI

2017

Wenta,T., Glaza,P., Jarzab,M., Zarzecka,U., Zurawa-Janicka,D., Lesner,A., Skorko-Glonek,J. and Lipinska,B. The role of the LB structural loop and its interactions with the PDZ domain of the human HtrA3 protease Biochim Biophys Acta (2017) 1865, 1141-1151. PubMed Europe PubMed DOI
Wysocka,M., Sychowska,K., Gruba,N., Winiarski,L., Skorenski,M., Psurski,M., Makowska,J., Gieldon,A., Wenta,T., Jarzab,M., Glaza,P., Zdancewicz,J., Sienczyk,M., Lipinska,B. and Lesner,A. Selection of effective HTRA3 activators using combinatorial chemistry ACS Comb Sci (2017) 19, 565-573. PubMed Europe PubMed DOI
Xudong,W., Guiying,Z., Guowen,F. and Yonggang,L. Molecular cloning of the porcine HTRA3 gene and association of a SNP with litter size traits Folia Biol (Praha) (2017) 63, 217-221. PubMed Europe PubMed M
Zurawa-Janicka,D., Wenta,T., Jarzab,M., Skorko-Glonek,J., Glaza,P., Gieldon,A., Ciarkowski,J. and Lipinska,B. Structural insights into the activation mechanisms of human HtrA serine proteases Arch Biochem Biophys (2017) 621, 6-23. PubMed Europe PubMed DOI V

2016

Liu,H., Dou,S.-F., Zhang,X., Wang,Y., Wen,Q.-L. and Mu,Y.-N. Rational improvement of peptide affinity to human pregnancy-related serine protease HtrA3 PDZ domain by introducing a halogen bond to the domain - peptide complex interface Int J Pept Res Ther (2016) 22, 371-376. DOI S

2015

Chatre,L., Biard,D.S., Sarasin,A. and Ricchetti,M. Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome Proc Natl Acad Sci U S A (2015) 112, E2910-E2919. PubMed Europe PubMed DOI
Glaza,P., Osipiuk,J., Wenta,T., Zurawa-Janicka,D., Jarzab,M., Lesner,A., Banecki,B., Skorko-Glonek,J., Joachimiak,A. and Lipinska,B. Structural and functional analysis of human HtrA3 protease and its subdomains PLoS ONE (2015) 10, e0131142-e0131142. PubMed Europe PubMed DOI PMC EPMC S

2014

Chen,Y.Y., Chuang,P.Y., Chen,C.P., Chiu,Y.H., Lo,H.F., Cheong,M.L., Huang,J.Y., Kuo,P.L. and Chen,H. Functional antagonism between high temperature requirement protein A (HtrA) family members regulates trophoblast invasion J Biol Chem (2014) 289, 22958-22968. PubMed Europe PubMed DOI
Singh,H., Nero,T.L., Wang,Y., Parker,M.W. and Nie,G. Activity-modulating monoclonal antibodies to the human serine protease HtrA3 provide novel insights into regulating HtrA proteolytic activities PLoS ONE (2014) 9, e108235-e108235. PubMed Europe PubMed DOI PMC EPMC

2013

Skorko-Glonek,J., Zurawa-Janicka,D., Koper,T., Jarzab,M., Figaj,D., Glaza,P. and Lipinska,B. HtrA protease family as therapeutic targets Curr Pharm Des (2013) 19, 977-1009. PubMed Europe PubMed V

2012

Beleford,D. and Shridhar,V. HtrA3 peptidase [ISSN:978-0-12-407742-3] (2012) 3, 2584-2590. DOI
Singh,H., Makino,S., Endo,Y., Li,Y., Stephens,A.N. and Nie,G. Application of the wheat-germ cell-free translation system to produce high temperature requirement A3 (HtrA3) proteases Biotechniques (2012) 52, 23-28. PubMed Europe PubMed DOI E

2011

Clausen,T., Kaiser,M., Huber,R. and Ehrmann,M. HTRA proteases: regulated proteolysis in protein quality control Nat Rev Mol Cell Biol (2011) 12, 152-162. PubMed Europe PubMed DOI V

2010

Beleford,D., Rattan,R., Chien,J. and Shridhar,V. High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines J Biol Chem (2010) 285, 12011-12027. PubMed Europe PubMed DOI
Bowden,M.A., Drummond,A.E., Fuller,P.J., Salamonsen,L.A., Findlay,J.K. and Nie,G. High-temperature requirement factor A3 (Htra3): a novel serine protease and its potential role in ovarian function and ovarian cancers Mol Cell Endocrinol (2010) 327, 13-18. PubMed Europe PubMed DOI
Singh,H., Makino,S.I., Endo,Y. and Nie,G. Inhibition of HTRA3 stimulates trophoblast invasion during human placental development Placenta (2010) 31, 1085-1092. PubMed Europe PubMed DOI

2009

Bowden,M., Drummond,A.E., Salamonsen,L.A., Findlay,J.K. and Nie,G. Evolutionary conservation of mammalian HTRA3 and its developmental regulation in the rat ovary J Exp Zool B Mol Dev Evol (2009) 312, 701-713. PubMed Europe PubMed DOI
Chien,J., Campioni,M., Shridhar,V. and Baldi,A. HtrA serine proteases as potential therapeutic targets in cancer Curr Cancer Drug Targets (2009) 9, 451-468. PubMed Europe PubMed DOI T
Kim,J.H., Kim,G.Y., Nam,M.K., Kim,S.S. and Rhim,H. Preparation of active human HtrA3 in Eschrichia coli and comparison of proteolytic activity between HtrA1, 2, and 3 Misainmurhag Hoiji (2009) 45, 291-299.

2007

Runyon,S.T., Zhang,Y., Appleton,B.A., Sazinsky,S.L., Wu,P., Pan,B., Wiesmann,C., Skelton,N.J. and Sidhu,S.S. Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3 Protein Sci (2007) 16, 2454-2471. PubMed Europe PubMed DOI PMC EPMC

2006

[YEAR:26-10-2006]Nie,G., Li,Y., Hale,K., Okada,H., Manuelpillai,U., Wallace,E.M. and Salamonsen,L.A. Serine peptidase HTRA3 is closely associated with human placental development and is elevated in pregnancy serum Biol Reprod (26-10-2006) 74, 366-374. PubMed Europe PubMed DOI
[YEAR:10-6-2006]Nie,G., Li,Y., He,H., Findlay,J.K. and Salamonsen,L.A. HtrA3, a serine protease possessing an IGF-binding domain, is selectively expressed at the maternal-fetal interface during placentation in the mouse Placenta (10-6-2006) 27, 491-501. PubMed Europe PubMed DOI

2005

Nie,G., Findlay,J.K. and Salamonsen,L.A. Identification of novel endometrial targets for contraception Contraception (2005) 71, 272-281. PubMed Europe PubMed DOI
Pellegrini,M., Bath,S., Marsden,V.S., Huang,D.C., Metcalf,D., Harris,A.W. and Strasser,A. FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells Blood (2005) 106, 1581-1589. PubMed Europe PubMed DOI PMC EPMC

2004

Dingwall,C. and Holbrook,J.D. Human HtrA proteases [ISSN:0-12-079610-4] (2004) 2, 1476-1480. V
Tocharus,J., Tsuchiya,A., Kajikawa,M., Ueta,Y., Oka,C. and Kawaichi,M. Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling Dev Growth Differ (2004) 46, 257-274. PubMed Europe PubMed DOI

2003

[YEAR:1-4-2003]Nie,G.Y., Hampton,A., Li,Y., Findlay,J.K. and Salamonsen,L.A. Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2 Biochem J (1-4-2003) 371, 39-48. PubMed Europe PubMed DOI PMC EPMC

1998

[YEAR:18-12-1998]Hu,S.I., Carozza,M., Klein,M., Nantermet,P., Luk,D. and Crowl,R.M. Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage J Biol Chem (18-12-1998) 273, 34406-34412. PubMed Europe PubMed DOI