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Literature for peptidase S01.246: kallikrein-related peptidase 10

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, M Mutation, R Splicing, P Specificity, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Palacios Serrato,E.G., Medina-Abreu,K.H., Oropeza-Martinez,E., Jacinto-Aleman,L.F., Macias-Silva,M. and Tecalco-Cruz,A.C.<br>ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role<br>World J Clin Oncol (2025) 16, 110202-110202. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Luo,Y.C., Lv,Y.L., He,R.X., Shi,X.X. and Jiang,T.<br>Kallikrein-related peptidase 10 predicts prognosis and mediates tumor immunomodulation in colorectal cancer<br>Biochem Biophys Res Commun (2023) 689, 149217-149217. PubMed  Europe PubMed DOI  K
    3. 2022
  3. Ahmad,S.M., Ahmed,B.S., Khidhir,K.G. and Rahman,H.S.<br>Prospective quantitative gene expression analysis of kallikrein-related peptidase KLK10 as a diagnostic biomarker for childhood acute lymphoblastic leukemia<br>PeerJ (2022) 10, e13489-e13489. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Williams,D., Mahmoud,M., Liu,R., Andueza,A., Kumar,S., Kang,D.W., Zhang,J., Tamargo,I., Villa-Roel,N., Baek,K.I., Lee,H., An,Y., Zhang,L., Tate,E.W., Bagchi,P., Pohl,J., Mosnier,L.O., Diamandis,E.P., Mihara,K., Hollenberg,M.D., Dai,Z. and Jo,H.<br>Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis<br>elife (2022) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  5. Zhao,J., Wang,Y., Wang,Y., Gao,J., Wu,X. and Li,H.<br>miR-194-3p represses the docetaxel resistance in colon cancer by targeting KLK10<br>Pathol Res Pract (2022) 236, 153962-153962. PubMed  Europe PubMed DOI
    6. 2020
  6. Wei,H., Dong,C. and Shen,Z.<br>Kallikrein-related peptidase (KLK10) cessation blunts colorectal cancer cell growth and glucose metabolism by regulating the PI3K/Akt/mTOR pathway<br>Neoplasma (2020) 67, 889-897. PubMed  Europe PubMed DOI
    7. 2016
  7. Debela,M., Magdolen,V., Bode,W., Brandstetter,H. and Goettig,P.<br>Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10<br>Biol Chem (2016) 397, 1251-1264. PubMed  Europe PubMed DOI  S
  8. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.<br>Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays<br>Mol Cell Proteomics (2016) 15, 2863-2876. PubMed  Europe PubMed DOI  A
    9. 2013
  9. Lundwall,A.<br>Old genes and new genes: The evolution of the kallikrein locus<br>Thromb Haemost (2013) 110, 469-475. PubMed  Europe PubMed DOI  V
    10. 2012
  10. Clements,J.A., Hooper,J.D. and Dong,Y.<br>The human tissue kallikrein and kallikrein-related peptidase family<br>[ISSN:978-0-12-407742-3] (2012) 3, 2747-2756. DOI
  11. Luo,L.Y. and Diamandis,E.P.<br>Human tissue kallikrein 10<br>[ISSN:978-0-12-407742-3] (2012) 3, 2798-2801. DOI
    12. 2010
  12. Batra,J., Tan,O.L., O'Mara,T., Zammit,R., Nagle,C.M., Clements,J.A., Kedda,M.A. and Spurdle,A.B.<br>Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphisms in ovarian cancer survival<br>Int J Gynecol Cancer (2010) 20, 529-536. PubMed  Europe PubMed DOI
    13. 2009
  13. Angelopoulou,K. and Karagiannis,G.S.<br>The canine kallikrein-related peptidases 9 and 10: structural characterization and expression in mammary cancer<br>Mamm Genome (2009) 20, 758-767. PubMed  Europe PubMed DOI
  14. Yoon,H., Blaber,S.I., Debela,M., Goettig,P., Scarisbrick,I.A. and Blaber,M.<br>A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15<br>Biol Chem (2009) 390, 373-377. PubMed  Europe PubMed DOI
    15. 2008
  15. Clements,J.A.<br>Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?<br>Biol Chem (2008) 389, 1447-1454. PubMed  Europe PubMed DOI  V
    16. 2007
  16. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.<br>Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis<br>Genomics (2007) 89, 429-438. PubMed  Europe PubMed DOI
  17. Kulasingam,V. and Diamandis,E.P.<br>Glucocorticoid receptor-mediated expression of kallikrein 10 in human breast cancer cell lines<br>Biol Chem (2007) 388, 1113-1119. PubMed  Europe PubMed DOI
  18. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.<br>Activation profiles and regulatory cascades of the human kallikrein-related peptidases<br>J Biol Chem (2007) 282, 31852-31864. PubMed  Europe PubMed DOI  V
    19. 2006
  19. [YEAR:1-6-2006]Debela,M., Magdolen,V., Schechter,N., Valachova,M., Lottspeich,F., Craik,C.S., Choe,Y., Bode,W. and Goettig,P.<br>Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences<br>J Biol Chem (1-6-2006) 281, 25678-25688. PubMed  Europe PubMed DOI  P
  20. Feng,B., Xu,W.B., Zheng,M.H., Ma,J.J., Cai,Q., Zhang,Y., Ji,J., Lu,A.G., Qu,Y., Li,J.W., Wang,M.L., Hu,W.G., Liu,B.Y. and Zhu,Z.G.<br>Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer<br>J Gastroenterol Hepatol (2006) 21, 1596-1603. PubMed  Europe PubMed DOI
    21. 2005
  21. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.<br>A survey of alternative transcripts of human tissue kallikrein genes<br>Biochim Biophys Acta (25-5-2005) 1755, 1-14. PubMed  Europe PubMed DOI  R
  22. [YEAR:9-8-2005]Yousef,G.M., White,N.M., Michael,I.P., Cho,J.C., Robb,J.D., Kurlender,L., Khan,S. and Diamandis,E.P.<br>Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker<br>Tumour Biol (9-8-2005) 26, 227-235. PubMed  Europe PubMed DOI
    23. 2004
  23. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.<br>The tissue kallikrein gene cluster<br>[ISSN:0-12-079610-4] (2004) 2, 1569-1577.  V
  24. Diamandis,E.P. and Luo,L.Y.<br>Human tissue kallikrein 10<br>[ISSN:0-12-079610-4] (2004) 2, 1593-1595.  V
    25. 2003
  25. [YEAR:15-2-2003]Luo,L.Y., Katsaros,D., Scorilas,A., Fracchioli,S., Bellino,R., Van Gramberen,M., De Bruijn,H., Henrik,A., Stenman,U.H., Massobrio,M., Van Der Zee,A.G., Vergote,I. and Diamandis,E.P.<br>The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis<br>Cancer Res (15-2-2003) 63, 807-811. PubMed  Europe PubMed
  26. Luo,L.Y., Grass,L. and Diamandis,E.P.<br>Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter<br>Clin Chim Acta (2003) 337, 115-126. PubMed  Europe PubMed DOI
  27. [YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.<br>Parallel overexpression of seven kallikrein genes in ovarian cancer<br>Cancer Res (1-5-2003) 63, 2223-2227. PubMed  Europe PubMed
    28. 2002
  28. [YEAR:1-4-2002]Bharaj,B.B., Luo,L.Y., Jung,K., Stephan,C. and Diamandis,E.P.<br>Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast,testicular, and ovarian cancers<br>Prostate (1-4-2002) 51, 35-41. PubMed  Europe PubMed DOI  M
  29. [YEAR:5-6-2002]Luo,L.Y., Diamandis,E.P., Look,M.P., Soosaipillai,A.P. and Foekens,J.A.<br>Higher expression of human kallikrein 10 in breast cancer tissue predicts tamoxifen resistance<br>Br J Cancer (5-6-2002) 86, 1790-1796. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Petraki,C.D., Karavana,V.N., Luo,L.Y. and Diamandis,E.P.<br>Human kallikrein 10 expression in normal tissues by immunohistochemistry<br>J Histochem Cytochem (2002) 50, 1247-1261. PubMed  Europe PubMed
    31. 2001
  31. Clements,J., Hooper,J., Dong,Y. and Harvey,T.<br>The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions<br>Biol Chem (2001) 382, 5-14. PubMed  Europe PubMed DOI  V
  32. Dhar,S., Bhargava,R., Yunes,M., Li,B., Goyal,J., Naber,S.P., Wazer,D.E. and Band,V.<br>Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer<br>Clin Cancer Res (2001) 7, 3393-3398. PubMed  Europe PubMed
  33. [YEAR:1-11-2001]Li,B., Goyal,J., Dhar,S., Dimri,G., Evron,E., Sukumar,S., Wazer,D.E. and Band,V.<br>CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression<br>Cancer Res (1-11-2001) 61, 8014-8021. PubMed  Europe PubMed
  34. Luo,L.Y., Grass,L., Howarth,D.J., Thibault,P., Ong,H. and Diamandis,E.P.<br>Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues<br>Clin Chem (2001) 47, 237-246. PubMed  Europe PubMed  A
  35. Luo,L.Y., Katsaros,D., Scorilas,A., Fracchioli,S., Piccinno,R., Rigault de la Longrais,I.A., Howarth,D.J. and Diamandis,E.P.<br>Prognostic value of human kallikrein 10 expression in epithelial ovarian carcinoma<br>Clin Cancer Res (2001) 7, 2372-2379. PubMed  Europe PubMed
  36. Luo,L.Y., Bunting,P., Scorilas,A. and Diamandis,E.P.<br>Human kallikrein 10: a novel tumor marker for ovarian carcinoma?<br>Clin Chim Acta (2001) 306, 111-118. PubMed  Europe PubMed DOI
  37. [YEAR:20-7-2001]Luo,L.Y., Rajpert-De Meyts,E.R., Jung,K. and Diamandis,E.P.<br>Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue<br>Br J Cancer (20-7-2001) 85, 220-224. PubMed  Europe PubMed DOI  PMC  EPMC
    38. 2000
  38. Diamandis,E.P., Yousef,G.M., Luo,L.Y., Magklara,A. and Obiezu,C.V.<br>The new human kallikrein gene family: implications in carcinogenesis<br>Trends Endocrinol Metab (2000) 11, 54-60. PubMed  Europe PubMed DOI
  39. Luo,L.Y., Grass,L. and Diamandis,E.P.<br>The normal epithelial cell-specific 1 (NES1) gene is up-regulated by steroid hormones in the breast carcinoma cell line BT-474<br>Anticancer Res (2000) 20, 981-986. PubMed  Europe PubMed
    40. 1999
  40. Yousef,G.M., Luo,L.Y. and Diamandis,E.P.<br>Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4<br>Anticancer Res (1999) 19, 2843-2852. PubMed  Europe PubMed
    41. 1998
  41. [YEAR:1-11-1998]Goyal,J., Smith,K.M., Cowan,J.M., Wazer,D.E., Lee,S.W. and Band,V.<br>The role for NES1 serine protease as a novel tumor suppressor<br>Cancer Res (1-11-1998) 58, 4782-4786. PubMed  Europe PubMed
    42. 1997
  42. Polikoff,D., Kuo,W.L., Cochran,J.F., Wernick,M., Kowbel,D., Myambo,K. and Collins,C.C.<br>Assignment of protease, serine-like 1 (PRSSL1) to human chromosome 19q13 by in situ hybridization and radiation hybrid mapping<br>Cytogenet Cell Genet (1997) 79, 147-148. PubMed  Europe PubMed
    43. 1996
  43. [YEAR:15-7-1996]Liu,X.L., Wazer,D.E., Watanabe,K. and Band,V.<br>Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression<br>Cancer Res (15-7-1996) 56, 3371-3379. PubMed  Europe PubMed

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