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Literature for peptidase S01.246: kallikrein-related peptidase 10

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, M Mutation, R Splicing, P Specificity, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Palacios Serrato,E.G., Medina-Abreu,K.H., Oropeza-Martinez,E., Jacinto-Aleman,L.F., Macias-Silva,M. and Tecalco-Cruz,A.C.
    ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role
    World J Clin Oncol (2025) 16, 110202-110202. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Luo,Y.C., Lv,Y.L., He,R.X., Shi,X.X. and Jiang,T.
    Kallikrein-related peptidase 10 predicts prognosis and mediates tumor immunomodulation in colorectal cancer
    Biochem Biophys Res Commun (2023) 689, 149217-149217. PubMed  Europe PubMed DOI  K
    3. 2022
  3. Ahmad,S.M., Ahmed,B.S., Khidhir,K.G. and Rahman,H.S.
    Prospective quantitative gene expression analysis of kallikrein-related peptidase KLK10 as a diagnostic biomarker for childhood acute lymphoblastic leukemia
    PeerJ (2022) 10, e13489-e13489. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Williams,D., Mahmoud,M., Liu,R., Andueza,A., Kumar,S., Kang,D.W., Zhang,J., Tamargo,I., Villa-Roel,N., Baek,K.I., Lee,H., An,Y., Zhang,L., Tate,E.W., Bagchi,P., Pohl,J., Mosnier,L.O., Diamandis,E.P., Mihara,K., Hollenberg,M.D., Dai,Z. and Jo,H.
    Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis
    elife (2022) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  5. Zhao,J., Wang,Y., Wang,Y., Gao,J., Wu,X. and Li,H.
    miR-194-3p represses the docetaxel resistance in colon cancer by targeting KLK10
    Pathol Res Pract (2022) 236, 153962-153962. PubMed  Europe PubMed DOI
    6. 2020
  6. Wei,H., Dong,C. and Shen,Z.
    Kallikrein-related peptidase (KLK10) cessation blunts colorectal cancer cell growth and glucose metabolism by regulating the PI3K/Akt/mTOR pathway
    Neoplasma (2020) 67, 889-897. PubMed  Europe PubMed DOI
    7. 2016
  7. Debela,M., Magdolen,V., Bode,W., Brandstetter,H. and Goettig,P.
    Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10
    Biol Chem (2016) 397, 1251-1264. PubMed  Europe PubMed DOI  S
  8. Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
    Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
    Mol Cell Proteomics (2016) 15, 2863-2876. PubMed  Europe PubMed DOI  A
    9. 2013
  9. Lundwall,A.
    Old genes and new genes: The evolution of the kallikrein locus
    Thromb Haemost (2013) 110, 469-475. PubMed  Europe PubMed DOI  V
    10. 2012
  10. Clements,J.A., Hooper,J.D. and Dong,Y.
    The human tissue kallikrein and kallikrein-related peptidase family
    [ISSN:978-0-12-407742-3] (2012) 3, 2747-2756. DOI
  11. Luo,L.Y. and Diamandis,E.P.
    Human tissue kallikrein 10
    [ISSN:978-0-12-407742-3] (2012) 3, 2798-2801. DOI
    12. 2010
  12. Batra,J., Tan,O.L., O'Mara,T., Zammit,R., Nagle,C.M., Clements,J.A., Kedda,M.A. and Spurdle,A.B.
    Kallikrein-related peptidase 10 (KLK10) expression and single nucleotide polymorphisms in ovarian cancer survival
    Int J Gynecol Cancer (2010) 20, 529-536. PubMed  Europe PubMed DOI
    13. 2009
  13. Angelopoulou,K. and Karagiannis,G.S.
    The canine kallikrein-related peptidases 9 and 10: structural characterization and expression in mammary cancer
    Mamm Genome (2009) 20, 758-767. PubMed  Europe PubMed DOI
  14. Yoon,H., Blaber,S.I., Debela,M., Goettig,P., Scarisbrick,I.A. and Blaber,M.
    A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15
    Biol Chem (2009) 390, 373-377. PubMed  Europe PubMed DOI
    15. 2008
  15. Clements,J.A.
    Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
    Biol Chem (2008) 389, 1447-1454. PubMed  Europe PubMed DOI  V
    16. 2007
  16. Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
    Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
    Genomics (2007) 89, 429-438. PubMed  Europe PubMed DOI
  17. Kulasingam,V. and Diamandis,E.P.
    Glucocorticoid receptor-mediated expression of kallikrein 10 in human breast cancer cell lines
    Biol Chem (2007) 388, 1113-1119. PubMed  Europe PubMed DOI
  18. Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
    Activation profiles and regulatory cascades of the human kallikrein-related peptidases
    J Biol Chem (2007) 282, 31852-31864. PubMed  Europe PubMed DOI  V
    19. 2006
  19. [YEAR:1-6-2006]Debela,M., Magdolen,V., Schechter,N., Valachova,M., Lottspeich,F., Craik,C.S., Choe,Y., Bode,W. and Goettig,P.
    Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences
    J Biol Chem (1-6-2006) 281, 25678-25688. PubMed  Europe PubMed DOI  P
  20. Feng,B., Xu,W.B., Zheng,M.H., Ma,J.J., Cai,Q., Zhang,Y., Ji,J., Lu,A.G., Qu,Y., Li,J.W., Wang,M.L., Hu,W.G., Liu,B.Y. and Zhu,Z.G.
    Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer
    J Gastroenterol Hepatol (2006) 21, 1596-1603. PubMed  Europe PubMed DOI
    21. 2005
  21. [YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
    A survey of alternative transcripts of human tissue kallikrein genes
    Biochim Biophys Acta (25-5-2005) 1755, 1-14. PubMed  Europe PubMed DOI  R
  22. [YEAR:9-8-2005]Yousef,G.M., White,N.M., Michael,I.P., Cho,J.C., Robb,J.D., Kurlender,L., Khan,S. and Diamandis,E.P.
    Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker
    Tumour Biol (9-8-2005) 26, 227-235. PubMed  Europe PubMed DOI
    23. 2004
  23. Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
    The tissue kallikrein gene cluster
    [ISSN:0-12-079610-4] (2004) 2, 1569-1577.  V
  24. Diamandis,E.P. and Luo,L.Y.
    Human tissue kallikrein 10
    [ISSN:0-12-079610-4] (2004) 2, 1593-1595.  V
    25. 2003
  25. [YEAR:15-2-2003]Luo,L.Y., Katsaros,D., Scorilas,A., Fracchioli,S., Bellino,R., Van Gramberen,M., De Bruijn,H., Henrik,A., Stenman,U.H., Massobrio,M., Van Der Zee,A.G., Vergote,I. and Diamandis,E.P.
    The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis
    Cancer Res (15-2-2003) 63, 807-811. PubMed  Europe PubMed
  26. Luo,L.Y., Grass,L. and Diamandis,E.P.
    Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter
    Clin Chim Acta (2003) 337, 115-126. PubMed  Europe PubMed DOI
  27. [YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.
    Parallel overexpression of seven kallikrein genes in ovarian cancer
    Cancer Res (1-5-2003) 63, 2223-2227. PubMed  Europe PubMed
    28. 2002
  28. [YEAR:1-4-2002]Bharaj,B.B., Luo,L.Y., Jung,K., Stephan,C. and Diamandis,E.P.
    Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast,testicular, and ovarian cancers
    Prostate (1-4-2002) 51, 35-41. PubMed  Europe PubMed DOI  M
  29. [YEAR:5-6-2002]Luo,L.Y., Diamandis,E.P., Look,M.P., Soosaipillai,A.P. and Foekens,J.A.
    Higher expression of human kallikrein 10 in breast cancer tissue predicts tamoxifen resistance
    Br J Cancer (5-6-2002) 86, 1790-1796. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Petraki,C.D., Karavana,V.N., Luo,L.Y. and Diamandis,E.P.
    Human kallikrein 10 expression in normal tissues by immunohistochemistry
    J Histochem Cytochem (2002) 50, 1247-1261. PubMed  Europe PubMed
    31. 2001
  31. Clements,J., Hooper,J., Dong,Y. and Harvey,T.
    The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
    Biol Chem (2001) 382, 5-14. PubMed  Europe PubMed DOI  V
  32. Dhar,S., Bhargava,R., Yunes,M., Li,B., Goyal,J., Naber,S.P., Wazer,D.E. and Band,V.
    Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer
    Clin Cancer Res (2001) 7, 3393-3398. PubMed  Europe PubMed
  33. [YEAR:1-11-2001]Li,B., Goyal,J., Dhar,S., Dimri,G., Evron,E., Sukumar,S., Wazer,D.E. and Band,V.
    CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression
    Cancer Res (1-11-2001) 61, 8014-8021. PubMed  Europe PubMed
  34. Luo,L.Y., Grass,L., Howarth,D.J., Thibault,P., Ong,H. and Diamandis,E.P.
    Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues
    Clin Chem (2001) 47, 237-246. PubMed  Europe PubMed  A
  35. Luo,L.Y., Katsaros,D., Scorilas,A., Fracchioli,S., Piccinno,R., Rigault de la Longrais,I.A., Howarth,D.J. and Diamandis,E.P.
    Prognostic value of human kallikrein 10 expression in epithelial ovarian carcinoma
    Clin Cancer Res (2001) 7, 2372-2379. PubMed  Europe PubMed
  36. Luo,L.Y., Bunting,P., Scorilas,A. and Diamandis,E.P.
    Human kallikrein 10: a novel tumor marker for ovarian carcinoma?
    Clin Chim Acta (2001) 306, 111-118. PubMed  Europe PubMed DOI
  37. [YEAR:20-7-2001]Luo,L.Y., Rajpert-De Meyts,E.R., Jung,K. and Diamandis,E.P.
    Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue
    Br J Cancer (20-7-2001) 85, 220-224. PubMed  Europe PubMed DOI  PMC  EPMC
    38. 2000
  38. Diamandis,E.P., Yousef,G.M., Luo,L.Y., Magklara,A. and Obiezu,C.V.
    The new human kallikrein gene family: implications in carcinogenesis
    Trends Endocrinol Metab (2000) 11, 54-60. PubMed  Europe PubMed DOI
  39. Luo,L.Y., Grass,L. and Diamandis,E.P.
    The normal epithelial cell-specific 1 (NES1) gene is up-regulated by steroid hormones in the breast carcinoma cell line BT-474
    Anticancer Res (2000) 20, 981-986. PubMed  Europe PubMed
    40. 1999
  40. Yousef,G.M., Luo,L.Y. and Diamandis,E.P.
    Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4
    Anticancer Res (1999) 19, 2843-2852. PubMed  Europe PubMed
    41. 1998
  41. [YEAR:1-11-1998]Goyal,J., Smith,K.M., Cowan,J.M., Wazer,D.E., Lee,S.W. and Band,V.
    The role for NES1 serine protease as a novel tumor suppressor
    Cancer Res (1-11-1998) 58, 4782-4786. PubMed  Europe PubMed
    42. 1997
  42. Polikoff,D., Kuo,W.L., Cochran,J.F., Wernick,M., Kowbel,D., Myambo,K. and Collins,C.C.
    Assignment of protease, serine-like 1 (PRSSL1) to human chromosome 19q13 by in situ hybridization and radiation hybrid mapping
    Cytogenet Cell Genet (1997) 79, 147-148. PubMed  Europe PubMed
    43. 1996
  43. [YEAR:15-7-1996]Liu,X.L., Wazer,D.E., Watanabe,K. and Band,V.
    Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression
    Cancer Res (15-7-1996) 56, 3371-3379. PubMed  Europe PubMed

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