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Literature for peptidase S01.176: batroxobin

Summary Alignment Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: A Assay, I Inhibitor, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Jia,Q., Zhu,J., Wu,D., Chen,T. and Hong,C.
    Comparison of Batroxobin Versus the Combination of Batroxobin and Intratympanic Dexamethasone Injection in the Treatment of Sudden Sensorineural Hearing Loss
    Ear Nose Throat J (2024) , 1455613231222381-1455613231222381. PubMed  Europe PubMed DOI
  2. Saladini,L.Y., Magalhaes-Junior,M.J., da Silva,C.C.F., Oliveira,P.G.C., Kodama,R.T., Gomes,L., Nishiyama-Jr,M.Y., Spencer,P.J., da Silva,W.D. and Portaro,F.C.V.
    Evaluation of the Inhibitory Potential of Synthetic Peptides Homologous to CDR3 Regions of a Monoclonal Antibody against Bothropic Venom Serine Proteases
    Int J Mol Sci (2024) 25 PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2021
  3. Lan,D., Song,S., Liu,Y., Jiao,B. and Meng,R.
    Use of Batroxobin in Central and Peripheral Ischemic Vascular Diseases: A Systematic Review
    Front Neurol (2021) 12, 716778-716778. PubMed  Europe PubMed DOI  PMC  EPMC  V
  4. Zhang,Z., Bao,X. and Li,D.
    Batroxobin inhibits astrocyte activation following nigrostriatal pathway injury
    Neural Regen Res (2021) 16, 721-726. PubMed  Europe PubMed DOI
    5. 2019
  5. Ding,J.Y., Pan,L.Q., Hu,Y.Y., Rajah,G.B., Zhou,D., Bai,C.B., Ya,J.Y., Wang,Z.A., Jin,K.X., Guan,J.W., Ding,Y.C., Ji,X.M. and Meng,R.
    Batroxobin in combination with anticoagulation may promote venous sinus recanalization in cerebral venous thrombosis: a real-world experience
    CNS Neurosci Ther (2019) 25, 638-646. PubMed  Europe PubMed DOI  U
  6. Masuda,H., Sato,A., Shizuno,T., Yokoyama,K., Suzuki,Y., Tokunaga,M. and Asahara,T.
    Batroxobin accelerated tissue repair via neutrophil extracellular trap regulation and defibrinogenation in a murine ischemic hindlimb model
    PLoS ONE (2019) 14, e0220898-e0220898. PubMed  Europe PubMed DOI  U
    7. 2018
  7. Amorim,F.G., Menaldo,D.L., Carone,S.E.I., Silva,T.A., Sartim,M.A., de Pauw,E., Quinton,L. and Sampaio,S.V.
    New insights on moojase, a thrombin-like serine protease from Bothrops moojeni snake venom
    Toxins (Basel) (2018) 10 PubMed  Europe PubMed DOI
  8. Choi,S.K., Kim,C.W., Kim,J.T., Seomun,Y., Park,M.S. and Kim,C.O.
    Coagulant effect and tolerability of yeast-produced recombinant batroxobin in healthy adult subjects
    Clin Drug Investig (2018) 38, 829-835. PubMed  Europe PubMed DOI  E
  9. Ding,J., Zhou,D., Hu,Y., Elmadhoun,O., Pan,L., Ya,J., Geng,T., Wang,Z., Ding,Y., Ji,X. and Meng,R.
    The efficacy and safety of batroxobin in combination with anticoagulation on cerebral venous sinus thrombosis
    J Thromb Thrombolysis (2018) 46, 371-378. PubMed  Europe PubMed DOI
  10. Seon,G.M., Lee,M.H., Kwon,B.J., Kim,M.S., Koo,M.A., Seomun,Y., Kim,J.T., Kim,T.H. and Park,J.C.
    Recombinant batroxobin-coated nonwoven chitosan as hemostatic dressing for initial hemorrhage control
    Int J Biol Macromol (2018) 113, 757-763. PubMed  Europe PubMed DOI  U
  11. Thelwell,C., Rigsby,P., Locke,M., Bevan,S. and Longstaff,C.
    An international collaborative study to calibrate the WHO 2nd International Standard for Ancrod (15/106) and the WHO Reference Reagent for Batroxobin (15/140): communication from the SSC of the ISTH
    J Thromb Haemost (2018) 16, 1003-1006. PubMed  Europe PubMed DOI  A
    12. 2017
  12. Kim,O.H., Cho,K.S., Seomun,Y., Kim,J.T. and Chung,K.H.
    Acute and repeated dose (28 days) toxicity studies in rats and dogs of recombinant batroxobin, a snake venom thrombin-like enzyme expressed from Pichia pastoris
    Toxicon (2017) 129, 153-163. PubMed  Europe PubMed DOI
  13. Seon,G.M., Lee,M.H., Kwon,B.J., Kim,M.S., Koo,M.A., Kim,D., Seomun,Y., Kim,J.T. and Park,J.C.
    Functional improvement of hemostatic dressing by addition of recombinant batroxobin
    Acta Biomater (2017) 48, 175-185. PubMed  Europe PubMed DOI  U
    14. 2016
  14. Li,D., Tong,L., Kawano,H., Liu,N., Liu,L. and Li,H.P.
    Protective effects of batroxobin on a nigrostriatal pathway injury in mice
    Brain Res Bull (2016) 127, 195-201. PubMed  Europe PubMed DOI  U
    15. 2015
  15. Hu,H.M., Chen,L., Frary,C.E., Chang,C.C., Hui,H., Zhang,H.P., Huang,D.G., Liu,Z.K., Zhao,Y.T., He,S.M., Zhang,X.F., He,B.R. and Hao,D.J.
    The beneficial effect of batroxobin on blood loss reduction in spinal fusion surgery: a prospective, randomized, double-blind, placebo-controlled study
    Arch Orthop Trauma Surg (2015) 135, 491-497. PubMed  Europe PubMed DOI  U
  16. Yu,H., Lin,B., He,Y., Zhang,W. and Xu,Y.
    Batroxobin protects against spinal cord injury in rats by promoting the expression of vascular endothelial growth factor to reduce apoptosis
    Exp Ther Med (2015) 9, 1631-1638. PubMed  Europe PubMed DOI  PMC  EPMC
    17. 2014
  17. You,K.E., Koo,M.A., Lee,D.H., Kwon,B.J., Lee,M.H., Hyon,S.H., Seomun,Y., Kim,J.T. and Park,J.C.
    The effective control of a bleeding injury using a medical adhesive containing batroxobin
    Biomed Mater (2014) 9, 025002-025002. PubMed  Europe PubMed DOI  U
    18. 2013
  18. Fan,H., Liu,X., Tang,H.B., Xiao,P., Wang,Y.Z. and Ju,G.
    Protective effects of batroxobin on spinal cord injury in rats
    Neurosci Bull (2013) 29, 501-508. PubMed  Europe PubMed DOI
  19. Serrano,S.M.T.
    The long road of research on snake venom serine proteinases
    Toxicon (2013) 62, 19-26. PubMed  Europe PubMed DOI
  20. Vu,T.T., Stafford,A.R., Leslie,B.A., Kim,P.Y., Fredenburgh,J.C. and Weitz,J.I.
    Batroxobin binds fibrin with higher affinity and promotes clot expansion to a greater extent than thrombin
    J Biol Chem (2013) 288, 16862-16871. PubMed  Europe PubMed DOI
  21. Zheng,Z.H., Zhu,X.X., Gan,H., Gu,R.L., Wu,Z.N., Meng,Z.Y. and Dou,G.F.
    [Pharmacodynamics and pharmacokinetics of batroxobin in Beagle dog]
    Yao Xue Xue Bao (2013) 48, 1307-1311. PubMed  Europe PubMed
    22. 2012
  22. Markland,F.S., Jr. and Swenson,S.
    Venombin A
    [ISSN:978-0-12-407742-3] (2012) 3, 3025-3034. DOI
  23. Xu,C., Wu,A. and Yue,Y.
    Which is more effective in adolescent idiopathic scoliosis surgery: batroxobin, tranexamic acid or a combination?
    Arch Orthop Trauma Surg (2012) 132, 25-31. PubMed  Europe PubMed DOI  I
    24. 2011
  24. Lei,Z., Shi,H.L., Li,L., Tao,Y.G., Yong,L.W., Senga,H., Renchi,Y. and Zhong,C.H.
    Batroxobin mobilizes circulating endothelial progenitor cells in patients with deep vein thrombosis
    Clin Appl Thromb Hemost (2011) 17, 75-79. PubMed  Europe PubMed DOI  U
  25. Wang,J., Zhu,Y.Q., Li,M.H., Zhao,J.G., Tan,H.Q., Wang,J.B., Liu,F. and Cheng,Y.S.
    Batroxobin plus aspirin reduces restenosis after angioplasty for arterial occlusive disease in diabetic patients with lower-limb ischemia
    J Vasc Interv Radiol (2011) 22, 987-994. PubMed  Europe PubMed DOI  U
  26. Yang,Y., Tian,S.J., Wu,L., Huang,D.H. and Wu,W.P.
    Fibrinogen depleting agent batroxobin has a beneficial effect on experimental autoimmune encephalomyelitis
    Cell Mol Neurobiol (2011) 31, 437-448. PubMed  Europe PubMed DOI
    27. 2010
  27. Lou,M.W., Wang,H., Gao,T.J. and Fan,Y.
    [A preliminary clinical study on the treatment of primary hepatic carcinoma by transcatheter arterial perfusion of batroxobin combined with TACE]
    Zhonghua Zhong Liu Za Zhi (2010) 32, 373-376. PubMed  Europe PubMed  U
  28. Magalhaes,H.P.B., de Sena,M.P.T. and Nelson,D.L.
    Kinetic characterization of leucurobin, a coagulant thrombin-like enzyme from the venom of Bothrops leucurus
    Open Toxicol J (2010) 4, 32-38. DOI
  29. Vilca-Quispe,A., Ponce-Soto,L.A., Winck,F.V. and Marangoni,S.
    Isolation and characterization of a new serine protease with thrombin-like activity (TLBm) from the venom of the snake Bothrops marajoensis
    Toxicon (2010) 55, 745-753. PubMed  Europe PubMed DOI
    30. 2009
  30. Wang,H.T., Jiang,W.L., Zhang,Y.N., Sun,Z.F., Sun,Q.F. and Ma,J.
    [Multicentre clinical observation of anticoagulation and thrombolysis for the deep venous thrombosis]
    Zhonghua Yi Xue Za Zhi (2009) 89, 3181-3185. PubMed  Europe PubMed  U
  31. Zeng,Z., Xiao,P., Chen,J. and Wei,Y.
    Are batroxobin agents effective for perioperative hemorrhage in thoracic surgery? A systematic review of randomized controlled trials
    Blood Coagul Fibrinolysis (2009) 20, 101-107. PubMed  Europe PubMed DOI
    32. 2007
  32. Magalhaes,A., Magalhaes,H.P., Richardson,M., Gontijo,S., Ferreira,R.N., Almeida,A.P. and Sanchez,E.F.
    Purification and properties of a coagulant thrombin-like enzyme from the venom of Bothrops leucurus
    Comp Biochem Physiol A Mol Integr Physiol (2007) 146, 565-575. PubMed  Europe PubMed DOI
    33. 2004
  33. Markland,F.S., Jr. and Swenson,S.
    Venombin A
    [ISSN:0-12-079610-4] (2004) 2, 1715-1723.  V
  34. [YEAR:30-7-2004]You,W.K., Choi,W.S., Koh,Y.S., Shin,H.C., Jang,Y. and Chung,K.H.
    Functional characterization of recombinant batroxobin, a snake venom thrombin-like enzyme, expressed from Pichia pastoris
    FEBS Lett (30-7-2004) 571, 67-73. PubMed  Europe PubMed DOI
    35. 1999
  35. [YEAR:15-12-1999]Iwai,S., Okazaki,M., Kiuchi,Y. and Oguchi,K.
    Changes in mRNA levels of fibrinogen subunit polypeptides in rats defibrinogenated with Batroxobin
    Thromb Res (15-12-1999) 96, 421-426. PubMed  Europe PubMed DOI
    36. 1997
  36. Bell,W.R., Jr.
    Defibrinogenating enzymes
    Drugs (1997) 54 Suppl 3, 18-30. PubMed  Europe PubMed  V
    37. 1995
  37. Lochnit,G. and Geyer,R.
    Carbohydrate structure analysis of batroxobin, a thrombin-like serine protease from Bothrops moojeni venom
    Eur J Biochem (1995) 228, 805-816. PubMed  Europe PubMed DOI
    38. 1992
  38. Tanaka,N., Nakada,H., Itoh,N., Mizuno,Y., Takanishi,M., Kawasaki,T., Tate,S., Inagaki,F. and Yamashina,I.
    Novel structure of the N-acetylgalactosamine containing N-glycosidic carbohydrate chain of batroxobin, a thrombin-like snake venom enzyme
    J Biochem (1992) 112, 68-74. PubMed  Europe PubMed
    39. 1991
  39. Maeda,M., Satoh,S., Suzuki,S., Niwa,M., Itoh,N. and Yamashina,I.
    Expression of cDNA for batroxobin, a thrombin-like snake venom enzyme
    J Biochem (1991) 109, 632-637. PubMed  Europe PubMed  E
    40. 1988
  40. Itoh,N., Tanaka,N., Funakoshi,I., Kawasaki,T., Mihashi,S. and Yamashina,I.
    Organization of the gene for batroxobin, a thrombin-like snake venom enzyme. Homology with the trypsin/kallikrein gene family
    J Biol Chem (1988) 263, 7628-7631. PubMed  Europe PubMed
  41. [YEAR:11-11-1988]Itoh,N., Tanaka,N., Funakoshi,I., Kawasaki,T., Mihashi,S. and Yamashina,I.
    The complete nucleotide sequence of the gene for batroxobin, a thrombin-like snake venom enzyme
    Nucleic Acids Res (11-11-1988) 16, 10377-10378. PubMed  Europe PubMed  PMC  EPMC
    42. 1987
  42. Itoh,N., Tanaka,N., Mihashi,S. and Yamashina,I.
    Molecular cloning and sequence analysis of cDNA for batroxobin, a thrombin-like snake venom enzyme
    J Biol Chem (1987) 262, 3132-3135. PubMed  Europe PubMed
    43. 1986
  43. Sturzebecher,J., Sturzebecher,U. and Markwardt,F.
    Inhibition of batroxobin, a serine proteinase from Bothrops snake venom, by derivatives of benzamidine
    Toxicon (1986) 24, 585-595. PubMed  Europe PubMed  I
    44. 1976
  44. [YEAR:31-8-1976]Aronson,D.L.
    Comparison of the actions of thrombin and the thrombin-like venom enzymes ancrod and batroxobin
    Thromb Haemost (31-8-1976) 36, 9-13. PubMed  Europe PubMed
  45. Holleman,W.H. and Weiss,L.J.
    The thrombin-like enzyme from Bothrops atrox snake venom. Properties of the enzyme purified by affinity chromatography on p-aminobenzamidine substituted agarose
    J Biol Chem (1976) 251, 1663-1669. PubMed  Europe PubMed  I
  46. Stocker,K. and Barlow,G.H.
    The coagulant enzyme from Bothrops atrox venom (batroxobin)
    Methods Enzymol (1976) 45, 214-223. PubMed  Europe PubMed DOI  V
    47. 1973
  47. Barlow,G.H., Lewis,J.L., Finley,R., Martin,D. and Stocker,K.
    Immunochemical identification of ancrod (A38414) and reptilase (defibrase)
    Thromb Res (1973) 2, 17-22.
  48. Latallo,Z.S. and Lopaciuk,S.
    New approach to thrombolytic therapy: the use of Defibrase in connection with streptokinase
    Thromb Diath Haemorrh Suppl (1973) 56, 253-264. PubMed  Europe PubMed
    49. 1971
  49. Funk,C., Gmur,J., Herold,R. and Straub,P.W.
    Reptilase-R - a new reagent in blood coagulation
    Br J Haematol (1971) 21, 43-52. PubMed  Europe PubMed
    50. 1937
  50. Eagle,H.
    The coagulation of blood by snake venoms and its physiologic significance
    J Exp Med (1937) 65, 613-639. PubMed  Europe PubMed  PMC  EPMC

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