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Literature for peptidase S01.153: elastase-1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: A Assay, S Structure, P Specificity, E Expression, V Review, M Mutation, I Inhibitor, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Jamwal,D., Kumar,P., Meena,K., Yadav,V., Kumar,R., Adlakha,N. and Das,S.
    Human CELA1 has pancreatic elastase-like activity
    Biochimie (2026) 243, 18-20. PubMed  Europe PubMed DOI
    2. 2024
  2. Abdollahi-Najafabadi,M., Farhadian,S., Shareghi,B. and Asgharzadeh,S.
    The investigation of the interaction determination between carbendazim and elastase, using both in vitro and in silico methods
    Spectrochim Acta A Mol Biomol Spectrosc (2024) 319, 124586-124586. PubMed  Europe PubMed DOI
  3. Ge,J., Weng,C., Zhang,X., Zhao,J., Zhang,H., Yuan,D. and Wang,T.
    A Mouse Abdominal Aortic Aneurysm Model by Periadventitial Calcium Chloride and Elastase Infiltration
    J Vis Exp (2024) PubMed  Europe PubMed DOI
    4. 2022
  4. Ahmed,A., Saeed,A., Ejaz,S.A., Aziz,M., Hashmi,M.Z., Channar,P.A., Abbas,Q., Raza,H., Shafiq,Z. and El-Seedi,H.R.
    Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies
    RSC Adv (2022) 12, 11974-11991. PubMed  Europe PubMed DOI  PMC  EPMC  I
  5. Li,H., Gao,Z. and Zhang,S.
    Localization of trypsin, chymotrypsin and elastase in the digestive tract of amphioxus Branchiostoma japonicum with implications to the origin of vertebrate pancreas
    Tissue Cell (2022) 79, 101943-101943. PubMed  Europe PubMed DOI
  6. Xiong,Y., Peng,P., Chen,S.J., Chang,M., Wang,Q., Yin,S.N. and Ren,D.F.
    Preparation, identification, and molecular docking of novel elastase inhibitory peptide from walnut (Juglans regia L.) meal
    Food Chem (Oxf) (2022) 5, 100139-100139. PubMed  Europe PubMed DOI  PMC  EPMC  I
    7. 2021
  7. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins
    Biol Chem (2021) 402, 861-867. PubMed  Europe PubMed DOI
  8. Ghosh,D., Bansode,S., Joshi,R., Kolte,B. and Gacche,R.
    Molecular elucidation of pancreatic elastase inhibition by baicalein
    J Biomol Struct Dyn (2021) , 1-10. PubMed  Europe PubMed DOI  I
  9. Mota,F.A.R., Pereira,S.A.P., Araujo,A.R.T.S. and Saraiva,M.L.M.F.
    Evaluation of Ionic Liquids and Ionic Liquids Active Pharmaceutical Ingredients Inhibition in Elastase Enzyme Activity
    Molecules (2021) 26 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Zheng,D., Wang,J., Li,G., An,L., Qu,Y., Zhang,Q., Ye,W., Zhao,X. and Zhao,Z.
    S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy
    Biochem Biophys Res Commun (2021) 562, 83-88. PubMed  Europe PubMed DOI
    11. 2020
  11. Becerra,D., Jeffs,S., Wojtkiewicz,G. and Ott,H.
    Characterization of an elastase-induced emphysema model in immune-deficient rats
    Eur J Cardiothorac Surg (2020) PubMed  Europe PubMed DOI
  12. Dige,N.C., Mahajan,P.G., Raza,H., Hassan,M., Vanjare,B.D., Hong,H., Lee,K.H., Latip,J. and Seo,S.Y.
    Synthesis and characterization of new 4H-chromene-3-carboxylates ensuring potent elastase inhibition activity along with their molecular docking and chemoinformatics properties
    Bioorg Chem (2020) 100, 103906-103906. PubMed  Europe PubMed DOI  I
  13. Kodama,R.T., Kuniyoshi,A.K., da Silva,C.C.F., Cajado-Carvalho,D., Duzzi,B., Mariano,D.C., Pimenta,D.C., Borges,R., da Silva,W.D. and Portaro,F.C.V.
    A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases
    J Venom Anim Toxins Incl Trop Dis (2020) 26, e20200037-e20200037. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Lee,J.H., Moon,S.H., Hong,Y., Ahn,D.U. and Paik,H.D.
    Anti-elastase and anti-hyaluronidase activity of phosvitin isolated from hen egg yolk
    Br Poult Sci (2020) 61, 17-21. PubMed  Europe PubMed DOI
  15. Li,G., Wei,H., Bi,J., Ding,X., Li,L., Xu,S., Yang,G. and Ren,W.
    Insights into dietary switch in cetaceans: evidence from molecular evolution of proteinases and lipases
    J Mol Evol (2020) PubMed  Europe PubMed DOI
  16. Sadeghi-Kaji,S., Shareghi,B., Saboury,A.A. and Farhadian,S.
    Spermine as a porcine pancreatic elastase activator: spectroscopic and molecular simulation studies
    J Biomol Struct Dyn (2020) 38, 78-88. PubMed  Europe PubMed DOI
  17. Sadeghi-Kaji,S., Shareghi,B., Saboury,A.A. and Farhadian,S.
    Investigating the interaction of porcine pancreatic elastase and propanol: a spectroscopy and molecular simulation study
    Int J Biol Macromol (2020) 146, 687-691. PubMed  Europe PubMed DOI
  18. Toumpanakis,D., Mizi,E., Vassilakopoulou,V., Dettoraki,M., Chatzianastasiou,A., Perlikos,F., Giatra,G., Moscholaki,M., Theocharis,S. and Vassilakopoulos,T.
    Spontaneous Breathing Through Increased Airway Resistance Augments Elastase-Induced Pulmonary Emphysema
    Int J Chron Obstruct Pulmon Dis (2020) 15, 1679-1688. PubMed  Europe PubMed DOI  PMC  EPMC
    19. 2019
  19. Butt,A.R.S., Abbasi,M.A., Aziz-Ur-Rehman, Siddiqui,S.Z., Hassan,M., Raza,H., Shah,S.A.A. and Seo,S.Y.
    Synthesis and structure-activity relationship of elastase inhibiting novel ethylated thiazole-triazole acetamide hybrids: mechanistic insights through kinetics and computational contemplations
    Bioorg Chem (2019) 86, 197-209. PubMed  Europe PubMed DOI  I
  20. Gloyn,A.L.
    Exocrine or endocrine? A circulating pancreatic elastase that regulates glucose homeostasis
    Nat Metab (2019) 1, 853-855. PubMed  Europe PubMed DOI
  21. Hamdani,S.S., Khan,B.A., Saeed,A., Larik,F.A., Hameed,S., Channar,P.A., Ahmad,K., Mughal,E.U., Abbas,Q., Amin,N.U., Ghumro,S.A., Maitlo,H., Hassan,M., Raza,H. and Seo,S.Y.
    Densely substituted piperidines as a new class of elastase inhibitors: synthesis and molecular modeling studies
    Arch Pharm (Weinheim) (2019) 352, e1900061-e1900061. PubMed  Europe PubMed DOI  I
    22. 2018
  22. Socan,J., Kazemi,M., Isaksen,G.V., Brandsdal,B.O. and Aqvist,J.
    Catalytic adaptation of psychrophilic elastase
    Biochemistry (2018) 57, 2984-2993. PubMed  Europe PubMed DOI
    23. 2017
  23. Boros,E., Szabo,A., Zboray,K., Heja,D., Pal,G. and Sahin-Toth,M.
    Overlapping specificity of duplicated human pancreatic elastase 3 isoforms and archetypal porcine elastase 1 provides clues to evolution of digestive enzymes
    J Biol Chem (2017) 292, 2690-2702. PubMed  Europe PubMed DOI  P
  24. Hasdemir,B., Sacan,O., Yasa,H., Kucuk,H.B., Yusufoglu,A.S. and Yanardag,R.
    Synthesis and elastase inhibition activities of novel aryl, substituted aryl, and heteroaryl oxime ester derivatives
    Arch Pharm (Weinheim) (2017) 351 PubMed  Europe PubMed DOI  I
    25. 2016
  25. Stergiou,P.Y., Foukis,A., Gkini,O.A., Bieth,J.G. and Papamichael,E.M.
    Kinetic and computational analysis of the reversible inhibition of porcine pancreatic elastase: a structural and mechanistic approach
    J Enzyme Inhib Med Chem (2016) 31, 131-139. PubMed  Europe PubMed DOI  I
  26. Wong,M.D., Bingham,K., Moss,E., Warn,J.D., Smirnov,I., Bland,K.S., Starcher,B., Franano,F.N. and Burke,S.K.
    Recombinant human elastase treatment of cephalic veins
    Cardiovasc Pharm Open Access (2016) 5 PubMed  Europe PubMed DOI  PMC  EPMC  U
    27. 2015
  27. Hernandez Gonzalez,J.E., Garcia-Fernandez,R. and Valiente,P.A.
    Polar desolvation and position 226 of pancreatic and neutrophil elastases are crucial to their affinity for the Kunitz-type inhibitors ShPI-1 and ShPI-1/K13L
    PLoS ONE (2015) 10, e0137787-e0137787. PubMed  Europe PubMed DOI  PMC  EPMC
    28. 2014
  28. Burke,S.K., Macdonald,K., Moss,E., Bunton,D., Starcher,B., Wong,M.D., Bland,K.S. and Franano,F.N.
    Effects of recombinant human type I pancreatic elastase on human atherosclerotic arteries
    J Cardiovasc Pharmacol (2014) 64, 530-535. PubMed  Europe PubMed DOI
  29. Han,M., Wang,X., Yan,G., Wang,W., Tao,Y., Liu,X., Cao,H. and Yu,X.
    Modification of recombinant elastase expressed in Pichia pastoris by introduction of N-glycosylation sites
    J Biotechnol (2014) 171, 3-7. PubMed  Europe PubMed DOI  E
  30. Liu,S., Young,S.M. and Varisco,B.M.
    Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development
    Am J Physiol Lung Cell Mol Physiol (2014) 306, L1104-L1116. PubMed  Europe PubMed DOI
    31. 2013
  31. Bunger,J.C., Melton-Celsa,A.R. and O'Brien,A.D.
    Shiga toxin type 2dact displays increased binding to globotriaosylceramide in vitro and increased lethality in mice after activation by elastase
    Toxins (Basel) (2013) 5, 2074-2092. PubMed  Europe PubMed DOI
  32. Qasim,M.A., Wang,L., Qasim,S., Lu,S., Lu,W., Wynn,R., Yi,Z.P. and Laskowski,M., Jr.
    Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB)
    FEBS Lett (2013) 587, 3021-3026. PubMed  Europe PubMed DOI
    33. 2012
  33. Monleon,L.M., Diez-Garcia,F., Zamora,H., Anaya,J., Grande,M., De Diego,J.G. and David Rodriguez,F.
    In vitro evaluation of the antielastase activity of polycyclic beta-lactams
    Bioorg Chem (2012) 45, 29-35. PubMed  Europe PubMed DOI  I
  34. Oliveira,E.B. and Salgado,M.C.O.
    Pancreatic elastases
    [ISSN:978-0-12-407742-3] (2012) 3, 2639-2645. DOI
  35. Qamar,A.A., Burke,S.K., Lafleur,J.D., Ding,B.C., Bland,K.S., Wong,M.D., Gustafson,P.N., Blair,A.T. and Franano,F.N.
    The ability of serum from alpha 1-antitrypsin-deficient patients to inhibit PRT-201, a recombinant human type I pancreatic elastase
    Biotechnol Appl Biochem (2012) 59, 22-28. PubMed  Europe PubMed DOI
  36. Santana,A.B., Lucas,S.D., Goncalves,L.M., Correia,H.F., Cardote,T.A., Guedes,R.C., Iley,J. and Moreira,R.
    N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases
    Bioorg Med Chem Lett (2012) 22, 3993-3997. PubMed  Europe PubMed DOI  I
    37. 2010
  37. Bras,N.F., Goncalves,R., Mateus,N., Fernandes,P.A., Ramos,M.J. and De Freitas,V.
    Inhibition of pancreatic elastase by polyphenolic compounds
    J Agric Food Chem (2010) 58, 10668-10676. PubMed  Europe PubMed DOI  I
  38. Sun,T., Zhang,S. and Ji,G.
    Identification and expression of an elastase homologue in Branchiostoma belcheri with implications to the origin of vertebrate pancreas
    Mol Biol Rep (2010) 37, 3303-3309. PubMed  Europe PubMed DOI
    39. 2009
  39. Rietschel,B., Arrey,T.N., Meyer,B., Bornemann,S., Schuerken,M., Karas,M. and Poetsch,A.
    Elastase digests: new ammunition for shotgun membrane proteomics
    Mol Cell Proteomics (2009) 8, 1029-1043. PubMed  Europe PubMed DOI  PMC  EPMC
  40. Tamada,T., Kinoshita,T., Kurihara,K., Adachi,M., Ohhara,T., Imai,K., Kuroki,R. and Tada,T.
    Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond
    J Am Chem Soc (2009) 131, 11033-11040. PubMed  Europe PubMed DOI  S
    41. 2008
  41. Mulchande,J., Guedes,R.C., Tsang,W.Y., Page,M.I., Moreira,R. and Iley,J.
    Azetidine-2,4-diones (4-oxo-beta-lactams) as scaffolds for designing elastase inhibitors
    J Med Chem (2008) 51, 1783-1790. PubMed  Europe PubMed DOI  I
  42. Nadarajah,D., Atkinson,M.A., Huebner,P. and Starcher,B.
    Enzyme kinetics and characterization of mouse pancreatic elastase
    Connect Tissue Res (2008) 49, 409-415. PubMed  Europe PubMed DOI
  43. Wang,B., Malik,R., Nigg,E.A. and Korner,R.
    Evaluation of the low-specificity protease elastase for large-scale phosphoproteome analysis
    Anal Chem (2008) 80, 9526-9533. PubMed  Europe PubMed DOI  P
    44. 2007
  44. Buzas,G.M.
    Pancreatic elastase: a forgotten Hungarian discovery
    Pancreatology (2007) 7, 546-546. PubMed  Europe PubMed DOI  V
  45. Korkmaz,B., Hajjar,E., Kalupov,T., Reuter,N., Brillard-Bourdet,M., Moreau,T., Juliano,L. and Gauthier,F.
    Influence of charge distribution at the active site surface on the substrate specificity of human neutrophil protease 3 and elastase. A kinetic and molecular modeling analysis
    J Biol Chem (2007) 282, 1989-1997. PubMed  Europe PubMed DOI  P
  46. Oliveira,T.F., Mulchande,J., Moreira,R., Iley,J. and Archer,M.
    Crystallization and preliminary diffraction studies of porcine pancreatic elastase in complex with a novel inhibitor
    Protein Pept Lett (2007) 14, 93-95. PubMed  Europe PubMed  I
  47. Tsang,W.Y., Ahmed,N., Hemming,K. and Page,M.I.
    Reactivity and selectivity in the inhibition of elastase by 3-oxo-beta-sultams and in their hydrolysis
    Org Biomol Chem (2007) 5, 3993-4000. PubMed  Europe PubMed DOI  I
    48. 2006
  48. Dementiev,A., Dobo,J. and Gettins,P.G.
    Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase
    J Biol Chem (2006) 281, 3452-3457. PubMed  Europe PubMed DOI  S
  49. Ding,X., Rasmussen,B.F., Petsko,G.A. and Ringe,D.
    Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: exploiting the "glass transition" in protein dynamics
    Bioorg Chem (2006) 34, 410-423. PubMed  Europe PubMed DOI  PMC  EPMC  S
  50. [YEAR:1-7-2006]Kinoshita,T., Yamaguchi,A. and Tada,T.
    Tris(hydroxymethyl)aminomethane induces conformational change and crystal-packing contraction of porcine pancreatic elastase
    Acta Crystallograph Sect F Struct Biol Cryst Commun (1-7-2006) 62, 623-626. PubMed  Europe PubMed DOI  PMC  EPMC  S
  51. Papaleo,E., Riccardi,L., Villa,C., Fantucci,P. and De Gioia,L.
    Flexibility and enzymatic cold-adaptation: a comparative molecular dynamics investigation of the elastase family
    Biochim Biophys Acta (2006) 1764, 1397-1406. PubMed  Europe PubMed DOI
  52. [YEAR:1-12-2006]Szepessy,E. and Sahin-Toth,M.
    Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans
    Pancreatology (1-12-2006) 6, 117-122. PubMed  Europe PubMed DOI  PMC  EPMC
    53. 2005
  53. [YEAR:29-6-2005]Tsang,W.Y., Ahmed,N., Harding,L.P., Hemming,K., Laws,A.P. and Page,M.I.
    Acylation versus sulfonylation in the inhibition of elastase by 3-oxo-beta-sultams
    J Am Chem Soc (29-6-2005) 127, 8946-8947. PubMed  Europe PubMed DOI  I
    54. 2004
  54. Bieth,J.G.
    Pancreatic elastase
    [ISSN:0-12-079610-4] (2004) 2, 1504-1508.  V
  55. [YEAR:8-10-2004]Hietaranta,A., Mustonen,H., Puolakkainen,P., Haapiainen,R. and Kemppainen,E.
    Proinflammatory effects of pancreatic elastase are mediated through TLR4 and NF-kappaB
    Biochem Biophys Res Commun (8-10-2004) 323, 192-196. PubMed  Europe PubMed DOI
  56. [YEAR:1-1-2004]Koizumi,M., Muratani,E., Fujii,K. and Takimoto-Kamimura,M.
    Crystal structure of the complex of porcine pancreatic elastase with TEI-8362
    J Synchrotron Radiat (1-1-2004) 11, 101-104. PubMed  Europe PubMed DOI  S  I
    57. 2003
  57. Ay,J., Hilpert,K., Krauss,N., Schneider-Mergener,J. and Hohne,W.
    Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution
    Acta Crystallogr D Biol Crystallogr (2003) 59, 247-254. PubMed  Europe PubMed DOI  S
  58. [YEAR:15-2-2003]Bousquet,J.A., Duranton,J., Mely,Y. and Bieth,J.G.
    Conformational change in elastase following complexation with alpha1-proteinase inhibitor: a CD investigation
    Biochem J (15-2-2003) 370, 345-349. PubMed  Europe PubMed DOI  PMC  EPMC
  59. [YEAR:6-1-2003]Kinoshita,T., Nakanishi,I., Sato,A. and Tada,T.
    True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor
    Bioorg Med Chem Lett (6-1-2003) 13, 21-24. PubMed  Europe PubMed DOI  S  I
  60. Matern,U., Schleberger,C., Jelakovic,S., Weckesser,J. and Schulz,G.E.
    Binding structure of elastase inhibitor scyptolin A
    Chem Biol (2003) 10, 997-1001. PubMed  Europe PubMed DOI  S  I
    61. 2002
  61. [YEAR:14-6-2002]Katona,G., Wilmouth,R.C., Wright,P.A., Berglund,G.I., Hajdu,J., Neutze,R. and Schofield,C.J.
    X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution
    J Biol Chem (14-6-2002) 277, 21962-21970. PubMed  Europe PubMed DOI  S
  62. Weiss,M.S., Panjikar,S., Nowak,E. and Tucker,P.A.
    Metal binding to porcine pancreatic elastase: calcium or not calcium
    Acta Crystallogr D Biol Crystallogr (2002) 58, 1407-1412. PubMed  Europe PubMed DOI  S
    63. 2001
  63. Wright,P.A., Wilmouth,R.C., Clifton,I.J. and Schofield,C.J.
    Kinetic and crystallographic analysis of complexes formed between elastase and peptides from beta-casein
    Eur J Biochem (2001) 268, 2969-2974. PubMed  Europe PubMed  S
    64. 2000
  64. Achilles,K., Schneider,M., Schirmeister,T. and Otto,H.H.
    beta-Lactam derivatives as enzyme inhibitors: N-substituted derivatives of (S)-4-oxoazetidine-2-carboxylate as inhibitors of elastase and papain
    Pharmazie (2000) 55, 798-802. PubMed  Europe PubMed  I
  65. [YEAR:15-4-2000]Nakanishi,I., Kinoshita,T., Sato,A. and Tada,T.
    Structure of porcine pancreatic elastase complexed with FR901277, a novel macrocyclic inhibitor of elastases, at 1.6 A resolution
    Biopolymers (15-4-2000) 53, 434-445. PubMed  Europe PubMed DOI  S  I
  66. Talas,U., Dunlop,J., Khalaf,S., Leigh,I.M. and Kelsell,D.P.
    Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism
    J Invest Dermatol (2000) 114, 165-170. PubMed  Europe PubMed DOI  M
  67. Wurtele,M., Hahn,M., Hilpert,K. and Hohne,W.
    Atomic resolution structure of native porcine pancreatic elastase at 1.1 A
    Acta Crystallogr D Biol Crystallogr (2000) 56, 520-523. PubMed  Europe PubMed DOI  S
    68. 1999
  68. [YEAR:6-8-1999]Guyonnet,V., Tluscik,F., Long,P.L., Polanowski,A. and Travis,J.
    Purification and partial characterization of the pancreatic proteolytic enzymes trypsin, chymotrypsin, and elastase from the chicken
    J Chromatogr A (6-8-1999) 852, 217-225. PubMed  Europe PubMed DOI
  69. [YEAR:27-8-1999]Taylor,P., Anderson,V., Dowden,J., Flitsch,S.L., Turner,N.J., Loughran,K. and Walkinshaw,M.D.
    Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes
    J Biol Chem (27-8-1999) 274, 24901-24905. PubMed  Europe PubMed DOI  S  I
    70. 1998
  70. Berglund,G.I., Smalas,A.O., Outzen,H. and Willassen,N.P.
    Purification and characterization of pancreatic elastase from North Atlantic salmon (Salmo salar)
    Mol Mar Biol Biotechnol (1998) 7, 105-114. PubMed  Europe PubMed
  71. Cregge,R.J., Durham,S.L., Farr,R.A., Gallion,S.L., Hare,C.M., Hoffman,R.V., Janusz,M.J., Kim,H.O., Koehl,J.R., Mehdi,S., Metz,W.A., Peet,N.P., Pelton,J.T., Schreuder,H.A., Sunder,S. and Tardif,C.
    Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones
    J Med Chem (1998) 41, 2461-2480. PubMed  Europe PubMed DOI  I
  72. [YEAR:5-3-1998]Packard,B.Z., Komoriya,A., Nanda,V. and Brand,L.
    Intramolecular excitonic dimers in protease substrates: modification of the backbone moiety to probe the H-dimer structure
    J Phys.Chem B (5-3-1998) 102, 1820-1827.  A
  73. [YEAR:15-12-1998]Wilmouth,R.C., Westwood,N.J., Anderson,K., Brownlee,W., Claridge,T.D., Clifton,I.J., Pritchard,G.J., Aplin,R.T. and Schofield,C.J.
    Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex
    Biochemistry (15-12-1998) 37, 17506-17513. PubMed  Europe PubMed DOI  I
    74. 1997
  74. Gestin,M., Le Huerou-Luron,I., Wicker-Planquart,C., Le Drean,G., Chaix,J.C., Puigserver,A. and Guilloteau,P.
    Bovine pancreatic preproelastases I and II: Comparison of nucleotide and amino acid sequences and tissue specific expression
    Comp Biochem Physiol B Biochem Mol Biol (1997) 118, 181-187. PubMed  Europe PubMed DOI
  75. [YEAR:1-9-1997]Packard,B.Z., Toptygin,D.D., Komoriya,A. and Brand,L.
    Characterization of fluorescence quenching in bifluorophoric protease substrates
    Biophys Chem (1-9-1997) 67, 167-176. PubMed  Europe PubMed  A
  76. Rao,S.K., Mathrubutham,M., Karteron,A., Sorensen,K. and Cohen,J.R.
    A versatile microassay for elastase using succinylated elastin
    Anal Biochem (1997) 250, 222-227. PubMed  Europe PubMed DOI  A
  77. Rose,S.D. and Macdonald,R.J.
    Evolutionary silencing of the human elastase I gene (ELA1)
    Hum Mol Genet (1997) 6, 897-903. PubMed  Europe PubMed DOI
    78. 1996
  78. [YEAR:10-9-1996]Tsunemi,M., Matsuura,Y., Sakakibara,S. and Katsube,Y.
    Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution
    Biochemistry (10-9-1996) 35, 11570-11576. PubMed  Europe PubMed DOI  S
    79. 1995
  79. Berglund,G.I., Willassen,N.P., Hordvik,A. and Smalas,A.O.
    Structure of native pancreatic elastase from North Atlantic salmon at 1.61 A resolution
    Acta Crystallogr D Biol Crystallogr (1995) 51, 925-937. PubMed  Europe PubMed DOI  S
  80. Berglund,G.I., Smalas,A.O., Hansen,L.K. and Willassen,N.P.
    Crystallization and preliminary X-ray crystallographic studies of native elastase from North Atlantic salmon (Salmo salar)
    Acta Crystallogr D Biol Crystallogr (1995) 51, 393-394. PubMed  Europe PubMed DOI  S
  81. Peisach,E., Casebier,D., Gallion,S.L., Furth,P., Petsko,G.A., Hogan,J.C., Jr. and Ringe,D.
    Interaction of a peptidomimetic aminimide inhibitor with elastase
    Science (1995) 269, 66-69. PubMed  Europe PubMed  S  I
    82. 1994
  82. Mattos,C., Rasmussen,B., Ding,X., Petsko,G.A. and Ringe,D.
    Analogous inhibitors of elastase do not always bind analogously
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    Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin Aalpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates
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    New mechanism-based serine protease inhibitors: inhibition of human leukocyte elastase, porcine pancreatic elastase, human leukocyte cathepsin G, and chymotrypsin by 3-chloroisocoumarin and 3,3-dichlorophthatide
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    Specificity and reactivity of human leukocyte elastase, porcine pancreatic elastase, human granulocyte cathepsin G, and bovine pancreatic chymotrypsin with arylsulfonyl fluorides. Discovery of a new series of potent and specific irreversible elastase inhibitors
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    Studies on reactivity of human leukocyte elastase, cathepsin G, and porcine pancreatic elastase toward peptides including sequences related to the reactive site of alpha 1-protease inhibitor (alpha 1-antitrypsin)
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    Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G. Inhibition with peptide chloromethyl ketones
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    131. 1975
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