Literature for peptidase S01.139: granzyme M

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: I Inhibitor, P Specificity, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2015
  1. Dotiwala,F., Fellay,I., Filgueira,L., Martinvalet,D., Lieberman,J. and Walch,M.
    A high yield and cost-efficient expression system of human granzymes in mammalian cells
    J Vis Expe52911-e52911. PubMed  Europe PubMed DOI  E
  2. 2014
  3. Baschuk,N., Wang,N., Watt,S.V., Halse,H., House,C., Bird,P.I., Strugnell,R., Trapani,J.A., Smyth,M.J. and Andrews,D.M.
    NK cell intrinsic regulation of MIP-1alpha by granzyme M
    Cell Death Dis5, e1115-e1115. PubMed  Europe PubMed DOI
  4. de Poot,S.A. and Bovenschen,N.
    Granzyme M: behind enemy lines
    Cell Death Differ21, 359-368. PubMed  Europe PubMed DOI  V
  5. de Poot,S.A., Lai,K.W., van der Wal,L., Plasman,K., Van Damme,P., Porter,A.C., Gevaert,K. and Bovenschen,N.
    Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis
    Cell Death Differ21, 416-426. PubMed  Europe PubMed DOI
  6. Plasman,K., Maurer-Stroh,S., Gevaert,K. and Van Damme,P.
    Holistic view on the extended substrate specificities of orthologous granzymes
    J Proteome Res13, 1785-1793. PubMed  Europe PubMed DOI  P
  7. Vahedi,F., Fraleigh,N., Vlasschaert,C., McElhaney,J. and Hanifi-Moghaddam,P.
    Human granzymes: related but far apart
    Med Hypotheses83, 688-693. PubMed  Europe PubMed DOI  V
  8. 2013
  9. de Poot,S.A., Lai,K.W., Hovingh,E.S. and Bovenschen,N.
    Granzyme M cannot induce cell death via cleavage of mouse FADD
    Apoptosis18, 533-534. PubMed  Europe PubMed DOI
  10. Schiffer,S., Letzian,S., Jost,E., Mladenov,R., Hristodorov,D., Huhn,M., Fischer,R., Barth,S. and Thepen,T.
    Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells
    Cancer Lett341, 178-185. PubMed  Europe PubMed DOI  U
  11. 2012
  12. Smyth,M.J., Andrews,D.M. and Baschuk,N.
    Granzyme M
    [ISSN:978-0-12-407742-3]3, 2728-2731. DOI
  13. 2011
  14. de Poot,S.A., Westgeest,M., Hostetter,D.R., Van Damme,P., Plasman,K., Demeyer,K., Broekhuizen,R., Gevaert,K., Craik,C.S. and Bovenschen,N.
    Human and mouse granzyme M display divergent and species-specific substrate specificities
    Biochem J437, 431-442. PubMed  Europe PubMed DOI  P
  15. Hollestelle,M.J., Lai,K.W., van Deuren,M., Lenting,P.J., DE Groot,P.G., Sprong,T. and Bovenschen,N.
    Cleavage of von Willebrand factor by granzyme M destroys its factor VIII binding capacity
    PLoS ONE6, e24216-e24216. PubMed  Europe PubMed DOI  P
  16. Khurshid,R., Saleem,M., Akhtar,M.S. and Salim,A.
    Granzyme M: characterization with sites of post-translational modification and specific sites of interaction with substrates and inhibitors
    Mol Biol Rep38, 2953-2960. PubMed  Europe PubMed DOI
  17. 2010
  18. Anthony,D.A., Andrews,D.M., Chow,M., Watt,S.V., House,C., Akira,S., Bird,P.I., Trapani,J.A. and Smyth,M.J.
    A role for granzyme M in TLR4-driven inflammation and endotoxicosis
    J Immunol185, 1794-1803. PubMed  Europe PubMed DOI
  19. Bovenschen,N. and Kummer,J.A.
    Orphan granzymes find a home
    Immunol Rev235, 117-127. PubMed  Europe PubMed DOI  V
  20. de Koning,P.J., Tesselaar,K., Bovenschen,N., Colak,S., Quadir,R., Volman,T.J. and Kummer,J.A.
    The cytotoxic protease granzyme M is expressed by lymphocytes of both the innate and adaptive immune system
    Mol Immunol47, 903-911. PubMed  Europe PubMed DOI
  21. Hu,D., Liu,S., Shi,L., Li,C., Wu,L. and Fan,Z.
    Cleavage of survivin by granzyme M triggers degradation of the survivin-X-linked inhibitor of apoptosis protein (XIAP) complex to free caspase activity leading to cytolysis of target tumor cells
    J Biol Chem285, 18326-18335. PubMed  Europe PubMed DOI
  22. van Domselaar,R., Philippen,L.E., Quadir,R., Wiertz,E.J., Kummer,J.A. and Bovenschen,N.
    Noncytotoxic inhibition of cytomegalovirus replication through NK cell protease granzyme M-mediated cleavage of viral phosphoprotein 71
    J Immunol185, 7605-7613. PubMed  Europe PubMed DOI
  23. 2009
  24. Cullen,S.P., Afonina,I.S., Donadini,R., Luthi,A.U., Medema,J.P., Bird,P.I. and Martin,S.J.
    Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing
    J Biol Chem284, 5137-5147. PubMed  Europe PubMed DOI  P
  25. de Koning,P.J., Kummer,J.A. and Bovenschen,N.
    Biology of granzyme M: a serine protease with unique features
    Crit Rev Immunol29, 307-315. PubMed  Europe PubMed
  26. Froelich,C.J., Pardo,J. and Simon,M.M.
    Granule-associated serine proteases: granzymes might not just be killer proteases
    Trends Immunol30, 117-123. PubMed  Europe PubMed DOI  V
  27. Wu,L., Wang,L., Hua,G., Liu,K., Yang,X., Zhai,Y., Bartlam,M., Sun,F. and Fan,Z.
    Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M
    J Immunol183, 421-429. PubMed  Europe PubMed DOI  P
  28. 2008
  29. Bovenschen,N., de Koning,P.J., Quadir,R., Broekhuizen,R., Damen,J.M., Froelich,C.J., Slijper,M. and Kummer,J.A.
    NK Cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network
    J Immunol180, 8184-8191. PubMed  Europe PubMed  P
  30. Chowdhury,D. and Lieberman,J.
    Death by a thousand cuts: granzyme pathways of programmed cell death
    Annu Rev Immunol26, 389-420. PubMed  Europe PubMed DOI  V
  31. 2006
  32. [YEAR:15-7-2006]Lu,H., Hou,Q., Zhao,T., Zhang,H., Zhang,Q., Wu,L. and Fan,Z.
    Granzyme M directly cleaves inhibitor of caspase-activated DNase (CAD) to unleash CAD leading to DNA fragmentation
    J Immunol177, 1171-1178. PubMed  Europe PubMed
  33. 2005
  34. [YEAR:1-9-2005]Pao,L.I., Sumaria,N., Kelly,J.M., van Dommelen,S., Cretney,E., Wallace,M.E., Anthony,D.A., Uldrich,A.P., Godfrey,D.I., Papadimitriou,J.M., Mullbacher,A., Degli-Esposti,M.A. and Smyth,M.J.
    Functional analysis of granzyme M and its role in immunity to infection
    J Immunol175, 3235-3243. PubMed  Europe PubMed
  35. 2004
  36. [YEAR:17-3-2004]Kelly,J.M., Waterhouse,N.J., Cretney,E., Browne,K.A., Ellis,S., Trapani,J.A. and Smyth,M.J.
    Granzyme M mediates a novel form of perforin-dependent cell death
    J Biol Chem279, 22236-22242. PubMed  Europe PubMed DOI
  37. [YEAR:19-11-2004]Mahrus,S., Kisiel,W. and Craik,C.S.
    Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B
    J Biol Chem279, 54275-54282. PubMed  Europe PubMed DOI  P
  38. [YEAR:1-2-2004]Rukamp,B.J., Kam,C.M., Natarajan,S., Bolton,B.W., Smyth,M.J., Kelly,J.M. and Powers,J.C.
    Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates
    Arch Biochem Biophys422, 9-22. PubMed  Europe PubMed DOI  P  I
  39. Smyth,M.J.
    Granzyme M
    [ISSN:0-12-079610-4]2, 1554-1556.  V
  40. 2003
  41. Grossman,W.J., Revell,P.A., Lu,Z.H., Johnson,H., Bredemeyer,A.J. and Ley,T.J.
    The orphan granzymes of humans and mice
    Curr Opin Immunol15, 544-552. PubMed  Europe PubMed DOI  V
  42. [YEAR:1-5-2003]Krenacs,L., Smyth,M.J., Bagdi,E., Krenacs,T., Kopper,L., Rudiger,T., Zettl,A., Muller-Hermelink,H.K., Jaffe,E.S. and Raffeld,M.
    The serine protease granzyme M is preferentially expressed in NK-cell, gamma delta T-cell, and intestinal T-cell lymphomas: evidence of origin from lymphocytes involved in innate immunity
    Blood101, 3590-3593. PubMed  Europe PubMed DOI
  43. [YEAR:5-9-2003]Sattar,R., Ali,S.A. and Abbasi,A.
    Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling
    Biochem Biophys Res Commun308, 726-735. PubMed  Europe PubMed DOI
  44. 2001
  45. [YEAR:15-1-2001]Sayers,T.J., Brooks,A.D., Ward,J.M., Hoshino,T., Bere,W.E., Wiegand,G.W., Kelly,J.M., Smyth,M.J. and Kelley,J.M.
    The restricted expression of granzyme M in human lymphocytes
    J Immunol166, 765-771. PubMed  Europe PubMed
  46. 1999
  47. Taniguchi,M., Tani,N., Suemoto,T., Ishimoto,I., Shiosaka,S. and Yoshida,S.
    High expression of alternative transcript of granzyme M in the mouse retina
    Neurosci Res34, 115-123. PubMed  Europe PubMed DOI
  48. 1996
  49. Kelly,J.M., O'Connor,M.D., Hulett,M.D., Thia,K.Y. and Smyth,M.J.
    Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1
    Immunogenetics44, 340-350. PubMed  Europe PubMed DOI
  50. Smyth,M.J., O'Connor,M.D., Trapani,J.A., Kershaw,M.H. and Brinkworth,R.I.
    A novel substrate-binding pocket interaction restricts the specificity of thehuman NK cell-specific serine protease, Met-ase-1
    J Immunol156, 4174-4181. PubMed  Europe PubMed
  51. Smyth,M.J., O'Connor,M.D. and Trapani,J.A.
    Granzymes: a variety of serine protease specificities encoded by genetically distinct subfamilies
    J Leukoc Biol60, 555-562. PubMed  Europe PubMed  V
  52. 1995
  53. Smyth,M.J., O'Connor,M.D., Kelly,J.M., Ganesvaran,P., Thia,K.Y. and Trapani,J.A.
    Expression of recombinant human MET-ASE-1: A NK cell-specific granzyme
    Biochem Biophys Res Commun217, 675-683. PubMed  Europe PubMed DOI
  54. Smyth,M.J., Hulett,M.D., Thia,K.Y., Young,H.A., Sayers,T.J., Carter,C.R. and Trapani,J.A.
    Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences
    Immunogenetics42, 101-111. PubMed  Europe PubMed
  55. Thia,K.Y., Jenkins,N.A., Gilbert,D.J., Copeland,N.G. and Smyth,M.J.
    The natural killer cell serine protease gene Lmet1 maps to mouse chromosome 10
    Immunogenetics41, 47-49. PubMed  Europe PubMed DOI
  56. 1994
  57. Baker,E., Sutherland,G.R. and Smyth,M.J.
    The gene encoding a human natural killer cell granule serine protease, Met-ase 1, maps to chromosome 19p13.3
    Immunogenetics39, 294-295. PubMed  Europe PubMed
  58. Pilat,D., Fink,T., Obermaier-Skrobanek,B., Zimmer,M., Wekerle,H., Lichter,P. and Jenne,D.E.
    The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3
    Genomics24, 445-450. PubMed  Europe PubMed DOI
  59. 1993
  60. [YEAR:1-12-1993]Smyth,M.J., Sayers,T.J., Wiltrout,T., Powers,J.C. and Trapani,J.A.
    Met-ase: Cloning and distinct chromosomal location of a serine protease preferentially expressed in human natural killer cells
    J Immunol151, 6195-6205. PubMed  Europe PubMed
  61. 1992
  62. [YEAR:5-12-1992]Smyth,M.J., Wiltrout,T., Trapani,J.A., Ottaway,K.S., Sowder,R., Henderson,L.E., Kam,C.M., Powers,J.C., Young,H.A. and Sayers,T.J.
    Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia
    J Biol Chem267, 24418-24425. PubMed  Europe PubMed