Literature for peptidase S01.087: TMPRSS13 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Joushomme,A., Desilets,A., Champagne,W., Hassanzadeh,M., Lemieux,G., Gravel-Trudeau,A., Lepage,M., Lafreniere,S., Froehlich,U., List,K., Boudreault,P.L. and Leduc,R. Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency J Enzyme Inhib Med Chem (2025) 40, 2466841-2466841. PubMed Europe PubMed DOI PMC EPMC I
Vegh,B., Kocsis,A., Dobo,J., Balczer,J., Kiss,B., Pal,G. and Gal,P. Efficient production of fully active, SARS-CoV-2-priming, wildtype TMPRSS2 ectodomain via co-expression of HAI-2 allows for both auto- and cross-activation mechanisms Biochem J (2025) 482, 1993-2010. PubMed Europe PubMed DOI

2024

Han,Y., Ma,Y., Wang,Z., Feng,F., Zhou,L., Feng,H., Ma,J., Ye,R. and Zhang,R. TMPRSS13 promotes the cell entry of swine acute diarrhea syndrome coronavirus J Med Virol (2024) 96, e29712-e29712. PubMed Europe PubMed DOI
Jin,Z., Zhang,Y., Chen,W., Li,H., Shi,L., Wang,D., Zhu,R. and Zhang,C. Intracellular autoactivation and surface location of hepsin, TMPRSS2, and TMPRSS13 Life Sci (2024) , 123299-123299. PubMed Europe PubMed DOI

2022

Martin,C.E., Murray,A.S., Mackinder,J.R., Sala-Hamrick,K.E., Flynn,M.G., Lundgren,J.G., Varela,F.A. and List,K. TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region Biol Chem (2022) 403, 969-982. PubMed Europe PubMed DOI

2021

Martin,C.E., Murray,A.S., Sala-Hamrick,K.E., Mackinder,J.R., Harrison,E.C., Lundgren,J.G., Varela,F.A. and List,K. Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization J Biol Chem (2021) 297, 101227-101227. PubMed Europe PubMed DOI PMC EPMC

2020

Murray,A.S., Hyland,T.E., Sala-Hamrick,K.E., Mackinder,J.R., Martin,C.E., Tanabe,L.M., Varela,F.A. and List,K. The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy Oncogene (2020) PubMed Europe PubMed DOI K

2014

Madsen,D.H., Szabo,R., Molinolo,A.A. and Bugge,T.H. TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition Biochem J (2014) 461, 487-495. PubMed Europe PubMed DOI K
Zmora,P., Blazejewska,P., Moldenhauer,A.S., Welsch,K., Nehlmeier,I., Wu,Q., Schneider,H., Pohlmann,S. and Bertram,S. DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry J Virol (2014) 88, 12087-12097. PubMed Europe PubMed DOI

2011

Antalis,T.M., Bugge,T.H. and Wu,Q. Membrane-anchored serine proteases in health and disease Prog Mol Biol Transl Sci (2011) 99, 1-50. PubMed Europe PubMed DOI V

2010

Hashimoto,T., Kato,M., Shimomura,T. and Kitamura,N. TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor FEBS J (2010) 277, 4888-4900. PubMed Europe PubMed DOI
Okumura,Y., Takahashi,E., Yano,M., Ohuchi,M., Daidoji,T., Nakaya,T., Bottcher,E., Garten,W., Klenk,H.D. and Kido,H. Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication J Virol (2010) 84, 5089-5096. PubMed Europe PubMed DOI R

2008

Kido,H. and Okumura,Y. Mspl/Tmprss13 Front Biosci (2008) 13, 754-758. PubMed Europe PubMed DOI V

2003

Szabo,R., Wu,Q., Dickson,R.B., Netzel-Arnett,S., Antalis,T.M. and Bugge,T.H. Type II transmembrane serine proteases Thromb Haemost (2003) 90, 185-193. PubMed Europe PubMed DOI V

2001

[YEAR:19-3-2001]Kim,D.R., Sharmin,S., Inoue,M. and Kido,H. Cloning and expression of novel mosaic serine proteases with and without a transmembrane domain from human lung Biochim Biophys Acta (19-3-2001) 1518, 204-209. PubMed Europe PubMed DOI