Literature for peptidase S01.087: TMPRSS13 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Joushomme,A., Desilets,A., Champagne,W., Hassanzadeh,M., Lemieux,G., Gravel-Trudeau,A., Lepage,M., Lafreniere,S., Froehlich,U., List,K., Boudreault,P.L. and Leduc,R.
    Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
    J Enzyme Inhib Med Chem (2025) 40, 2466841-2466841. PubMed  Europe PubMed DOI  PMC  EPMC  I
  2. Vegh,B., Kocsis,A., Dobo,J., Balczer,J., Kiss,B., Pal,G. and Gal,P.
    Efficient production of fully active, SARS-CoV-2-priming, wildtype TMPRSS2 ectodomain via co-expression of HAI-2 allows for both auto- and cross-activation mechanisms
    Biochem J (2025) 482, 1993-2010. PubMed  Europe PubMed DOI
  3. 2024
  4. Han,Y., Ma,Y., Wang,Z., Feng,F., Zhou,L., Feng,H., Ma,J., Ye,R. and Zhang,R.
    TMPRSS13 promotes the cell entry of swine acute diarrhea syndrome coronavirus
    J Med Virol (2024) 96, e29712-e29712. PubMed  Europe PubMed DOI
  5. Jin,Z., Zhang,Y., Chen,W., Li,H., Shi,L., Wang,D., Zhu,R. and Zhang,C.
    Intracellular autoactivation and surface location of hepsin, TMPRSS2, and TMPRSS13
    Life Sci (2024) , 123299-123299. PubMed  Europe PubMed DOI
  6. 2022
  7. Martin,C.E., Murray,A.S., Mackinder,J.R., Sala-Hamrick,K.E., Flynn,M.G., Lundgren,J.G., Varela,F.A. and List,K.
    TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region
    Biol Chem (2022) 403, 969-982. PubMed  Europe PubMed DOI
  8. 2021
  9. Martin,C.E., Murray,A.S., Sala-Hamrick,K.E., Mackinder,J.R., Harrison,E.C., Lundgren,J.G., Varela,F.A. and List,K.
    Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization
    J Biol Chem (2021) 297, 101227-101227. PubMed  Europe PubMed DOI  PMC  EPMC
  10. 2020
  11. Murray,A.S., Hyland,T.E., Sala-Hamrick,K.E., Mackinder,J.R., Martin,C.E., Tanabe,L.M., Varela,F.A. and List,K.
    The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy
    Oncogene (2020) PubMed  Europe PubMed DOI  K
  12. 2014
  13. Madsen,D.H., Szabo,R., Molinolo,A.A. and Bugge,T.H.
    TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition
    Biochem J (2014) 461, 487-495. PubMed  Europe PubMed DOI  K
  14. Zmora,P., Blazejewska,P., Moldenhauer,A.S., Welsch,K., Nehlmeier,I., Wu,Q., Schneider,H., Pohlmann,S. and Bertram,S.
    DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry
    J Virol (2014) 88, 12087-12097. PubMed  Europe PubMed DOI
  15. 2011
  16. Antalis,T.M., Bugge,T.H. and Wu,Q.
    Membrane-anchored serine proteases in health and disease
    Prog Mol Biol Transl Sci (2011) 99, 1-50. PubMed  Europe PubMed DOI  V
  17. 2010
  18. Hashimoto,T., Kato,M., Shimomura,T. and Kitamura,N.
    TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor
    FEBS J (2010) 277, 4888-4900. PubMed  Europe PubMed DOI
  19. Okumura,Y., Takahashi,E., Yano,M., Ohuchi,M., Daidoji,T., Nakaya,T., Bottcher,E., Garten,W., Klenk,H.D. and Kido,H.
    Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication
    J Virol (2010) 84, 5089-5096. PubMed  Europe PubMed DOI  R
  20. 2008
  21. Kido,H. and Okumura,Y.
    Mspl/Tmprss13
    Front Biosci (2008) 13, 754-758. PubMed  Europe PubMed DOI  V
  22. 2003
  23. Szabo,R., Wu,Q., Dickson,R.B., Netzel-Arnett,S., Antalis,T.M. and Bugge,T.H.
    Type II transmembrane serine proteases
    Thromb Haemost (2003) 90, 185-193. PubMed  Europe PubMed DOI  V
  24. 2001
  25. [YEAR:19-3-2001]Kim,D.R., Sharmin,S., Inoue,M. and Kido,H.
    Cloning and expression of novel mosaic serine proteases with and without a transmembrane domain from human lung
    Biochim Biophys Acta (19-3-2001) 1518, 204-209. PubMed  Europe PubMed DOI