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Literature for peptidase S01.079: transmembrane peptidase, serine 3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: M Mutation, T Target, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Rezaie,N., Ghazanfari,S.S., Mousavikia,S.M., Mansour Samaei,N., Oladnabi,M., Sarli,A. and Khosravi,T.
    A novel frameshift variant in the TMPRSS3 gene causes nonsyndromic hearing loss in a consanguineous family
    BMC Med Genomics17, 283-283. PubMed  Europe PubMed DOI
  2. Wang,Y., Liang,Y., Huang,B., Cen,X., Huang,L. and Chen,K.
    [Late-onset hereditary hearing loss caused by TMPRSS3 compound heterozygous mutations]
    Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi38, 679-686. PubMed  Europe PubMed DOI
  3. Zhang,X., Wu,J., Wang,M., Chen,L., Wang,P., Jiang,Q. and Yang,C.
    The role of gene mutations and immune responses in sensorineural hearing loss
    Int Immunopharmacol143, 113515-113515. PubMed  Europe PubMed DOI  V
    4. 2022
  4. Chen,Y.S., Cabrera,E., Tucker,B.J., Shin,T.J., Moawad,J.V., Totten,D.J., Booth,K.T. and Nelson,R.F.
    TMPRSS3 expression is limited in spiral ganglion neurons: implication for successful cochlear implantation
    J Med Genet59, 1219-1226. PubMed  Europe PubMed DOI  V
  5. Wen,J.Y., Fang,Y.Y., Chen,G., He,R.Q., Huang,H.Q., Wang,R.S., Zeng,D.T., Huang,W.J. and Qin,X.G.
    Upregulation of the transmembrane protease serine 3 mRNA level in radioresistant colorectal cancer tissues
    Biomark Med16, 693-715. PubMed  Europe PubMed DOI
    6. 2019
  6. Zhang,Z.W., Pang,B., Chen,Y.C. and Peng,A.Q.
    TMPRSS3 regulates cell viability and apoptosis processes of HEI-OC1 cells via regulation on circ-Slc4a2, miR-182, and AKT cascade
    J Gene Mede3118-e3118. PubMed  Europe PubMed DOI
    7. 2018
  7. Li,S.L., Chen,X., Wu,T., Zhang,X.W., Li,H., Zhang,Y. and Ji,Z.Z.
    Knockdown of TMPRSS3 inhibits gastric cancer cell proliferation, invasion and EMT via regulation of the ERK1/2 and PI3K/Akt pathways
    Biomed Pharmacother107, 841-848. PubMed  Europe PubMed DOI  K  T
  8. Liu,W., Lowenheim,H., Santi,P.A., Glueckert,R., Schrott-Fischer,A. and Rask-Andersen,H.
    Expression of trans-membrane serine protease 3 (TMPRSS3) in the human organ of Corti
    Cell Tissue Res372, 445-456. PubMed  Europe PubMed DOI
  9. Wang,J.Y., Jin,X. and Li,X.F.
    Knockdown of TMPRSS3, a transmembrane serine protease, inhibits proliferation, migration, and invasion in human nasopharyngeal carcinoma cells
    Oncol Res26, 95-101. PubMed  Europe PubMed DOI
    10. 2017
  10. Gao,X., Huang,S.S., Yuan,Y.Y., Xu,J.C., Gu,P., Bai,D., Kang,D.Y., Han,M.Y., Wang,G.J., Zhang,M.G., Li,J. and Dai,P.
    Identification of TMPRSS3 as a significant contributor to autosomal recessive hearing loss in the Chinese population
    Neural Plast2017, 3192090-3192090. PubMed  Europe PubMed DOI  M
    11. 2016
  11. Battelino,S., Klancar,G., Kovac,J., Battelino,T. and Trebusak Podkrajsek,K.
    TMPRSS3 mutations in autosomal recessive nonsyndromic hearing loss
    Eur Arch Otorhinolaryngol273, 1151-1154. PubMed  Europe PubMed DOI  M
  12. Zhang,D., Qiu,S., Wang,Q. and Zheng,J.
    TMPRSS3 modulates ovarian cancer cell proliferation, invasion and metastasis
    Oncol Rep35, 81-88. PubMed  Europe PubMed DOI  T
    13. 2014
  13. Chung,J., Park,S.M., Chang,S.O., Chung,T., Lee,K.Y., Kim,A.R., Park,J.H., Kim,V., Park,W.Y., Oh,S.H., Kim,D., Park,W.J. and Choi,B.Y.
    A novel mutation of TMPRSS3 related to milder auditory phenotype in Korean postlingual deafness: a possible future implication for a personalized auditory rehabilitation
    J Mol Med (Berl)92, 651-663. PubMed  Europe PubMed DOI  M
  14. Li,Y., Peng,A., Ge,S., Wang,Q. and Liu,J.
    miR-204 suppresses cochlear spiral ganglion neuron survival in vitro by targeting TMPRSS3
    Hear Res314, 60-64. PubMed  Europe PubMed DOI
    15. 2013
  15. Molina,L., Fasquelle,L., Nouvian,R., Salvetat,N., Scott,H.S., Guipponi,M., Molina,F., Puel,J.L. and Delprat,B.
    Tmprss3 loss of function impairs cochlear inner hair cell Kcnma1 channel membrane expression
    Hum Mol Genet22, 1289-1299. PubMed  Europe PubMed DOI
    16. 2012
  16. Lee,K., Khan,S., Islam,A., Ansar,M., Andrade,P.B., Kim,S., Santos-Cortez,R.L., Ahmad,W. and Leal,S.M.
    Novel TMPRSS3 variants in Pakistani families with autosomal recessive non-syndromic hearing impairment
    Clin Genet82, 56-63. PubMed  Europe PubMed DOI  M
    17. 2011
  17. Antalis,T.M., Bugge,T.H. and Wu,Q.
    Membrane-anchored serine proteases in health and disease
    Prog Mol Biol Transl Sci99, 1-50. PubMed  Europe PubMed DOI  V
  18. Fasquelle,L., Scott,H.S., Lenoir,M., Wang,J., Rebillard,G., Gaboyard,S., Venteo,S., Francois,F., Mausset-Bonnefont,A.L., Antonarakis,S.E., Neidhart,E., Chabbert,C., Puel,J.L., Guipponi,M. and Delprat,B.
    Tmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing
    J Biol Chem286, 17383-17397. PubMed  Europe PubMed DOI  K
    19. 2008
  19. Guipponi,M., Toh,M.Y., Tan,J., Park,D., Hanson,K., Ballana,E., Kwong,D., Cannon,P.Z., Wu,Q., Gout,A., Delorenzi,M., Speed,T.P., Smith,R.J., Dahl,H.H., Petersen,M., Teasdale,R.D., Estivill,X., Park,W.J. and Scott,H.S.
    An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss
    Hum Mutat29, 130-141. PubMed  Europe PubMed DOI
  20. Guipponi,M., Antonarakis,S.E. and Scott,H.S.
    TMPRSS3, a type II transmembrane serine protease mutated in non-syndromic autosomal recessive deafness
    Front Biosci13, 1557-1567. PubMed  Europe PubMed DOI  V
    21. 2007
  21. Elbracht,M., Senderek,J., Eggermann,T., Thurmer,C., Park,J., Westhofen,M. and Zerres,K.
    Autosomal recessive postlingual hearing loss (DFNB8): compound heterozygosity for two novel TMPRSS3 mutations in German siblings
    J Med Genet44, e81-e81. PubMed  Europe PubMed DOI  M
    22. 2005
  22. [YEAR:14-7-2005]Wattenhofer,M., Sahin-Calapoglu,N., Andreasen,D., Kalay,E., Caylan,R., Braillard,B., Fowler-Jaeger,N., Reymond,A., Rossier,B.C., Karaguzel,A. and Antonarakis,S.E.
    A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein
    Hum Genet117, 528-535. PubMed  Europe PubMed DOI  M
    23. 2004
  23. [YEAR:24-9-2004]Ahmed,Z.M., Li,X.C., Powell,S.D., Riazuddin,S., Young,T.L., Ramzan,K., Ahmad,Z., Luscombe,S., Dhillon,K., MacLaren,L., Ploplis,B., Shotland,L.I., Ives,E., Riazuddin,S., Friedman,T.B., Morell,R.J. and Wilcox,E.R.
    Characterization of a new full length TMPRSS3 isoform and identification of mutant alleles responsible for nonsyndromic recessive deafness in Newfoundland and Pakistan
    BMC Med Genet5, 24-24. PubMed  Europe PubMed DOI
  24. Sawasaki,T., Shigemasa,K., Gu,L., Beard,J.B. and O'Brien,T.J.
    The transmembrane protease serine (TMPRSS3/TADG-12) D variant: a potential candidate for diagnosis and therapeutic intervention in ovarian cancer
    Tumour Biol25, 141-148. PubMed  Europe PubMed DOI
    25. 2003
  25. Lee,Y.J., Park,D., Kim,S.Y. and Park,W.J.
    Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3
    J Med Genet40, 629-631. PubMed  Europe PubMed  M
  26. Szabo,R., Wu,Q., Dickson,R.B., Netzel-Arnett,S., Antalis,T.M. and Bugge,T.H.
    Type II transmembrane serine proteases
    Thromb Haemost90, 185-193. PubMed  Europe PubMed DOI  V
    27. 2002
  27. [YEAR:1-11-2002]Guipponi,M., Vuagniaux,G., Wattenhofer,M., Shibuya,K., Vazquez,M., Dougherty,L., Scamuffa,N., Guida,E., Okui,M., Rossier,C., Hancock,M., Buchet,K., Reymond,A., Hummler,E., Marzella,P.L., Kudoh,J., Shimizu,N., Scott,H.S., Antonarakis,S.E. and Rossier,B.C.
    The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro
    Hum Mol Genet11, 2829-2836. PubMed  Europe PubMed
    28. 2001
  28. Ben-Yosef,T., Wattenhofer,M., Riazuddin,S., Ahmed,Z.M., Scott,H.S., Kudoh,J., Shibuya,K., Antonarakis,S.E., Bonne-Tamir,B., Radhakrishna,U., Naz,S., Ahmed,Z., Riazuddin,S., Pandya,A., Nance,W.E., Wilcox,E.R., Friedman,T.B. and Morell,R.J.
    Novel mutations of TMPRSS3 in four DFNB8/B10 families segregating congenital autosomal recessive deafness
    J Med Genet38, 396-400. PubMed  Europe PubMed
  29. Masmoudi,S., Antonarakis,S.E., Schwede,T., Ghorbel,A.M., Gratri,M., Pappasavas,M.P., Drira,M., Elgaied-Boulila,A., Wattenhofer,M., Rossier,C., Scott,H.S., Ayadi,H. and Guipponi,M.
    Novel missense mutations of TMPRSS3 in two consanguineous Tunisian families with non-syndromic autosomal recessive deafness
    Hum Mutat18, 101-108. PubMed  Europe PubMed DOI
  30. Scott,H.S., Kudoh,J., Wattenhofer,M., Shibuya,K., Berry,A., Chrast,R., Guipponi,M., Wang,J., Kawasaki,K., Asakawa,S., Minoshima,S., Younus,F., Mehdi,S.Q., Radhakrishna,U., Papasavvas,M.P., Gehrig,C., Rossier,C., Korostishevsky,M., Gal,A., Shimizu,N., Bonne-Tamir,B. and Antonarakis,S.E.
    Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness
    Nat Genet27, 59-63. PubMed  Europe PubMed DOI
    31. 2000
  31. [YEAR:15-11-2000]Underwood,L.J., Shigemasa,K., Tanimoto,H., Beard,J.B., Schneider,E.N., Wang,Y., Parmley,T.H. and O'Brien,T.J.
    Ovarian tumor cells express a novel multi-domain cell surface serine protease
    Biochim Biophys Acta1502, 337-350. PubMed  Europe PubMed DOI

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