Literature for peptidase S01.025: mast cell peptidase 6 (mouse numbering)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, K Knockout, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Grujic,M., Hellman,L., Gustafson,A.M., Akula,S., Melo,F.R. and Pejler,G.<br>Protective role of mouse mast cell tryptase Mcpt6 in melanoma<br>Pigment Cell Melanoma Res (2020) 33, 579-590. PubMed  Europe PubMed DOI  K
  2. Magnusdottir,E.I., Grujic,M., Bergman,J., Pejler,G. and Lagerstrom,M.C.<br>Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1<br>J Neuroinflammation (2020) 17, 123-123. PubMed  Europe PubMed DOI  PMC  EPMC
  3. 2019
  4. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.<br>Highly selective cleavage of TH2-promoting cytokines by the human and the mouse mast cell tryptases, indicating a potent negative feedback loop on TH2 immunity<br>Int J Mol Sci (2019) 20 PubMed  Europe PubMed DOI  P
  5. Santosh Martin,S., Rabelo Melo,F. and Pejler,G.<br>The absence of tryptase Mcpt6 causes elevated cellular stress in response to modulation of the histone acetylation status in mast cells<br>Cells (2019) 8 PubMed  Europe PubMed DOI  K
  6. 2015
  7. de Souza Junior,D.A., Borges,A.C., Santana,A.C., Oliver,C. and Jamur,M.C.<br>Mast cell proteases 6 and 7 stimulate angiogenesis by inducing endothelial cells to release angiogenic factors<br>PLoS ONE (2015) 10, e0144081-e0144081. PubMed  Europe PubMed DOI
  8. 2014
  9. Cui,Y., Dahlin,J.S., Feinstein,R., Bankova,L.G., Xing,W., Shin,K., Gurish,M.F. and Hallgren,J.<br>Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma<br>J Immunol (2014) 193, 4783-4789. PubMed  Europe PubMed DOI
  10. 2013
  11. Beckett,E.L., Stevens,R.L., Jarnicki,A.G., Kim,R.Y., Hanish,I., Hansbro,N.G., Deane,A., Keely,S., Horvat,J.C., Yang,M., Oliver,B.G., van Rooijen,N., Inman,M.D., Adachi,R., Soberman,R.J., Hamadi,S., Wark,P.A., Foster,P.S. and Hansbro,P.M.<br>A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis<br>J Allergy Clin Immunol (2013) 131, 752-762. PubMed  Europe PubMed DOI  K
  12. Magarinos,N.J., Bryant,K.J., Fosang,A.J., Adachi,R., Stevens,R.L. and McNeil,H.P.<br>Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens<br>J Immunol (2013) 191, 1404-1412. PubMed  Europe PubMed DOI
  13. 2012
  14. Zheng,D. and Stevens,R.L.<br>Mouse mast cell tetramer-forming tryptases<br>[ISSN:978-0-12-407742-3] (2012) 3, 2698-2705. DOI
  15. 2011
  16. Zhang,J., Sun,J., Lindholt,J.S., Sukhova,G.K., Sinnamon,M., Stevens,R.L., Adachi,R., Libby,P., Thompson,R.W. and Shi,G.P.<br>Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation<br>Circ Res (2011) 108, 1316-1327. PubMed  Europe PubMed DOI
  17. 2010
  18. de Vries,V.C., Elgueta,R., Lee,D.M. and Noelle,R.J.<br>Mast cell protease 6 is required for allograft tolerance<br>Transplant Proc (2010) 42, 2759-2762. PubMed  Europe PubMed DOI
  19. 2008
  20. McNeil,H.P., Shin,K., Campbell,I.K., Wicks,I.P., Adachi,R., Lee,D.M. and Stevens,R.L.<br>The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis<br>Arthritis Rheum (2008) 58, 2338-2346. PubMed  Europe PubMed DOI
  21. Shin,K., Watts,G.F., Oettgen,H.C., Friend,D.S., Pemberton,A.D., Gurish,M.F. and Lee,D.M.<br>Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection<br>J Immunol (2008) 180, 4885-4891. PubMed  Europe PubMed
  22. 2007
  23. Abraham,D., Oster,H., Huber,M. and Leitges,M.<br>The expression pattern of three mast cell specific proteases during mouse development<br>Mol Immunol (2007) 44, 732-740. PubMed  Europe PubMed DOI
  24. Stevens,R.L. and Adachi,R.<br>Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity<br>Immunol Rev (2007) 217, 155-167. PubMed  Europe PubMed DOI
  25. Thakurdas,S.M., Melicoff,E., Sansores-Garcia,L., Moreira,D.C., Petrova,Y., Stevens,R.L. and Adachi,R.<br>The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections<br>J Biol Chem (2007) 282, 20809-20815. PubMed  Europe PubMed DOI  K
  26. 2005
  27. Funaba,M., Ikeda,T., Murakami,M., Ogawa,K. and Abe,M.<br>Up-regulation of mouse mast cell protease-6 gene by transforming growth factor-beta and activin in mast cell progenitors<br>Cell Signal (2005) 17, 121-128. PubMed  Europe PubMed DOI
  28. 2001
  29. [YEAR:19-6-2001]Hallgren,J., Estrada,S., Karlson,U., Alving,K. and Pejler,G.<br>Heparin antagonists are potent inhibitors of mast cell tryptase<br>Biochemistry (19-6-2001) 40, 7342-7349. PubMed  Europe PubMed
  30. [YEAR:21-12-2001]Morii,E., Ogihara,H., Oboki,K., Kataoka,T.R., Jippo,T. and Kitamura,Y.<br>Effect of MITF on transcription of transmembrane tryptase gene in cultured mast cells of mice<br>Biochem Biophys Res Commun (21-12-2001) 289, 1243-1246. PubMed  Europe PubMed DOI
  31. 2000
  32. [YEAR:7-1-2000]Huang,C., Morales,G., Vagi,A., Chanasyk,K., Ferrazzi,M., Burklow,C., Qiu,W.T., Feyfant,E., Sali,A. and Stevens,R.L.<br>Formation of enzymatically active, homotypic, and heterotypic tetramers of mouse mast cell tryptases. Dependence on a conserved Trp-rich domain on the surface<br>J Biol Chem (7-1-2000) 275, 351-358. PubMed  Europe PubMed DOI  E
  33. 1999
  34. [YEAR:15-3-1999]Jippo,T., Lee,Y.M., Katsu,Y., Tsujino,K., Morii,E., Kim,D.K., Kim,H.M. and Kitamura,Y.<br>Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype<br>Blood (15-3-1999) 93, 1942-1950. PubMed  Europe PubMed
  35. 1998
  36. Huang,C., Sali,A. and Stevens,R.L.<br>Regulation and function of mast cell proteases in inflammation<br>J Clin Immunol (1998) 18, 169-183. PubMed  Europe PubMed DOI
  37. [YEAR:15-2-1998]Huang,C., Friend,D.S., Qiu,W.T., Wong,G.W., Morales,G., Hunt,J. and Stevens,R.L.<br>Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6<br>J Immunol (15-2-1998) 160, 1910-1919. PubMed  Europe PubMed
  38. 1997
  39. Lutzelschwab,C., Pejler,G., Aveskogh,M. and Hellman,L.<br>Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations<br>J Exp Med (1997) 185, 13-29. PubMed  Europe PubMed DOI  PMC  EPMC
  40. 1996
  41. Ghildyal,N., Friend,D.S., Stevens,R.L., Austen,K.F., Huang,C., Penrose,J.F., Sali,A. and Gurish,M.F.<br>Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood<br>J Exp Med (1996) 184, 1061-1073. PubMed  Europe PubMed  PMC  EPMC
  42. Morii,E., Tsujimura,T., Jippo,T., Hashimoto,K., Takebayashi,K., Tsujino,K., Nomura,S., Yamamoto,M. and Kitamura,Y.<br>Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus<br>Blood (1996) 88, 2488-2494. PubMed  Europe PubMed
  43. 1995
  44. Springman,E.B. and Serafin,W.E.<br>Structure, genetics, and regulation of expression of secretory endo- and exopeptidases of mouse mast cells<br>Clin Allergy Immunol (1995) 6, 169-201.
  45. 1994
  46. Huang,R. and Hellman,L.<br>Genes for mast-cell serine protease and their molecular evolution<br>Immunogenetics (1994) 40, 397-414. PubMed  Europe PubMed
  47. 1991
  48. [YEAR:25-2-1991]Reynolds,D.S., Gurley,D.S., Austen,K.F. and Serafin,W.E.<br>Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass<br>J Biol Chem (25-2-1991) 266, 3847-3853. PubMed  Europe PubMed
  49. 1990
  50. Reynolds,D.S., Stevens,R.L., Lane,W.S., Carr,M.H., Austen,K.F. and Serafin,W.E.<br>Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases<br>Proc Natl Acad Sci U S A (1990) 87, 3230-3234. PubMed  Europe PubMed  PMC  EPMC