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Literature for peptidase S01.025: mast cell peptidase 6 (mouse numbering)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, K Knockout, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Grujic,M., Hellman,L., Gustafson,A.M., Akula,S., Melo,F.R. and Pejler,G.
    Protective role of mouse mast cell tryptase Mcpt6 in melanoma
    Pigment Cell Melanoma Res (2020) 33, 579-590. PubMed  Europe PubMed DOI  K
  2. Magnusdottir,E.I., Grujic,M., Bergman,J., Pejler,G. and Lagerstrom,M.C.
    Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1
    J Neuroinflammation (2020) 17, 123-123. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2019
  3. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Highly selective cleavage of TH2-promoting cytokines by the human and the mouse mast cell tryptases, indicating a potent negative feedback loop on TH2 immunity
    Int J Mol Sci (2019) 20 PubMed  Europe PubMed DOI  P
  4. Santosh Martin,S., Rabelo Melo,F. and Pejler,G.
    The absence of tryptase Mcpt6 causes elevated cellular stress in response to modulation of the histone acetylation status in mast cells
    Cells (2019) 8 PubMed  Europe PubMed DOI  K
    5. 2015
  5. de Souza Junior,D.A., Borges,A.C., Santana,A.C., Oliver,C. and Jamur,M.C.
    Mast cell proteases 6 and 7 stimulate angiogenesis by inducing endothelial cells to release angiogenic factors
    PLoS ONE (2015) 10, e0144081-e0144081. PubMed  Europe PubMed DOI
    6. 2014
  6. Cui,Y., Dahlin,J.S., Feinstein,R., Bankova,L.G., Xing,W., Shin,K., Gurish,M.F. and Hallgren,J.
    Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
    J Immunol (2014) 193, 4783-4789. PubMed  Europe PubMed DOI
    7. 2013
  7. Beckett,E.L., Stevens,R.L., Jarnicki,A.G., Kim,R.Y., Hanish,I., Hansbro,N.G., Deane,A., Keely,S., Horvat,J.C., Yang,M., Oliver,B.G., van Rooijen,N., Inman,M.D., Adachi,R., Soberman,R.J., Hamadi,S., Wark,P.A., Foster,P.S. and Hansbro,P.M.
    A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
    J Allergy Clin Immunol (2013) 131, 752-762. PubMed  Europe PubMed DOI  K
  8. Magarinos,N.J., Bryant,K.J., Fosang,A.J., Adachi,R., Stevens,R.L. and McNeil,H.P.
    Mast cell-restricted, tetramer-forming tryptases induce aggrecanolysis in articular cartilage by activating matrix metalloproteinase-3 and -13 zymogens
    J Immunol (2013) 191, 1404-1412. PubMed  Europe PubMed DOI
    9. 2012
  9. Zheng,D. and Stevens,R.L.
    Mouse mast cell tetramer-forming tryptases
    [ISSN:978-0-12-407742-3] (2012) 3, 2698-2705. DOI
    10. 2011
  10. Zhang,J., Sun,J., Lindholt,J.S., Sukhova,G.K., Sinnamon,M., Stevens,R.L., Adachi,R., Libby,P., Thompson,R.W. and Shi,G.P.
    Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation
    Circ Res (2011) 108, 1316-1327. PubMed  Europe PubMed DOI
    11. 2010
  11. de Vries,V.C., Elgueta,R., Lee,D.M. and Noelle,R.J.
    Mast cell protease 6 is required for allograft tolerance
    Transplant Proc (2010) 42, 2759-2762. PubMed  Europe PubMed DOI
    12. 2008
  12. McNeil,H.P., Shin,K., Campbell,I.K., Wicks,I.P., Adachi,R., Lee,D.M. and Stevens,R.L.
    The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis
    Arthritis Rheum (2008) 58, 2338-2346. PubMed  Europe PubMed DOI
  13. Shin,K., Watts,G.F., Oettgen,H.C., Friend,D.S., Pemberton,A.D., Gurish,M.F. and Lee,D.M.
    Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection
    J Immunol (2008) 180, 4885-4891. PubMed  Europe PubMed
    14. 2007
  14. Abraham,D., Oster,H., Huber,M. and Leitges,M.
    The expression pattern of three mast cell specific proteases during mouse development
    Mol Immunol (2007) 44, 732-740. PubMed  Europe PubMed DOI
  15. Stevens,R.L. and Adachi,R.
    Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity
    Immunol Rev (2007) 217, 155-167. PubMed  Europe PubMed DOI
  16. Thakurdas,S.M., Melicoff,E., Sansores-Garcia,L., Moreira,D.C., Petrova,Y., Stevens,R.L. and Adachi,R.
    The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections
    J Biol Chem (2007) 282, 20809-20815. PubMed  Europe PubMed DOI  K
    17. 2005
  17. Funaba,M., Ikeda,T., Murakami,M., Ogawa,K. and Abe,M.
    Up-regulation of mouse mast cell protease-6 gene by transforming growth factor-beta and activin in mast cell progenitors
    Cell Signal (2005) 17, 121-128. PubMed  Europe PubMed DOI
    18. 2001
  18. [YEAR:19-6-2001]Hallgren,J., Estrada,S., Karlson,U., Alving,K. and Pejler,G.
    Heparin antagonists are potent inhibitors of mast cell tryptase
    Biochemistry (19-6-2001) 40, 7342-7349. PubMed  Europe PubMed
  19. [YEAR:21-12-2001]Morii,E., Ogihara,H., Oboki,K., Kataoka,T.R., Jippo,T. and Kitamura,Y.
    Effect of MITF on transcription of transmembrane tryptase gene in cultured mast cells of mice
    Biochem Biophys Res Commun (21-12-2001) 289, 1243-1246. PubMed  Europe PubMed DOI
    20. 2000
  20. [YEAR:7-1-2000]Huang,C., Morales,G., Vagi,A., Chanasyk,K., Ferrazzi,M., Burklow,C., Qiu,W.T., Feyfant,E., Sali,A. and Stevens,R.L.
    Formation of enzymatically active, homotypic, and heterotypic tetramers of mouse mast cell tryptases. Dependence on a conserved Trp-rich domain on the surface
    J Biol Chem (7-1-2000) 275, 351-358. PubMed  Europe PubMed DOI  E
    21. 1999
  21. [YEAR:15-3-1999]Jippo,T., Lee,Y.M., Katsu,Y., Tsujino,K., Morii,E., Kim,D.K., Kim,H.M. and Kitamura,Y.
    Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype
    Blood (15-3-1999) 93, 1942-1950. PubMed  Europe PubMed
    22. 1998
  22. Huang,C., Sali,A. and Stevens,R.L.
    Regulation and function of mast cell proteases in inflammation
    J Clin Immunol (1998) 18, 169-183. PubMed  Europe PubMed DOI
  23. [YEAR:15-2-1998]Huang,C., Friend,D.S., Qiu,W.T., Wong,G.W., Morales,G., Hunt,J. and Stevens,R.L.
    Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6
    J Immunol (15-2-1998) 160, 1910-1919. PubMed  Europe PubMed
    24. 1997
  24. Lutzelschwab,C., Pejler,G., Aveskogh,M. and Hellman,L.
    Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations
    J Exp Med (1997) 185, 13-29. PubMed  Europe PubMed DOI  PMC  EPMC
    25. 1996
  25. Ghildyal,N., Friend,D.S., Stevens,R.L., Austen,K.F., Huang,C., Penrose,J.F., Sali,A. and Gurish,M.F.
    Fate of two mast cell tryptases in V3 mastocytosis and normal BALB/c mice undergoing passive systemic anaphylaxis: prolonged retention of exocytosed mMCP-6 in connective tissues, and rapid accumulation of enzymatically active mMCP-7 in the blood
    J Exp Med (1996) 184, 1061-1073. PubMed  Europe PubMed  PMC  EPMC
  26. Morii,E., Tsujimura,T., Jippo,T., Hashimoto,K., Takebayashi,K., Tsujino,K., Nomura,S., Yamamoto,M. and Kitamura,Y.
    Regulation of mouse mast cell protease 6 gene expression by transcription factor encoded by the mi locus
    Blood (1996) 88, 2488-2494. PubMed  Europe PubMed
    27. 1995
  27. Springman,E.B. and Serafin,W.E.
    Structure, genetics, and regulation of expression of secretory endo- and exopeptidases of mouse mast cells
    Clin Allergy Immunol (1995) 6, 169-201.
    28. 1994
  28. Huang,R. and Hellman,L.
    Genes for mast-cell serine protease and their molecular evolution
    Immunogenetics (1994) 40, 397-414. PubMed  Europe PubMed
    29. 1991
  29. [YEAR:25-2-1991]Reynolds,D.S., Gurley,D.S., Austen,K.F. and Serafin,W.E.
    Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass
    J Biol Chem (25-2-1991) 266, 3847-3853. PubMed  Europe PubMed
    30. 1990
  30. Reynolds,D.S., Stevens,R.L., Lane,W.S., Carr,M.H., Austen,K.F. and Serafin,W.E.
    Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases
    Proc Natl Acad Sci U S A (1990) 87, 3230-3234. PubMed  Europe PubMed  PMC  EPMC

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